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Gene | ROS1 |
Variant | Q1797H |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 Q1797H lies within fibronectin type-III domain 9 of the Ros1 protein (UniProt.org). Q1797H has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 Q1797H |
Transcript | NM_002944.3 |
gDNA | chr6:g.117326390C>A |
cDNA | c.5391G>T |
Protein | p.Q1797H |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.3 | chr6:g.117326390C>A | c.5391G>T | p.Q1797H | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117326390C>A | c.5391G>T | p.Q1797H | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117326390C>A | c.5391G>T | p.Q1797H | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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