RVU120
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| Drug Name | RVU120 |
| Trade Name | |
| Synonyms | SEL120|SEL 120-34|SEL120-34A|RVU 120|RVU-120 |
| Drug Descriptions |
RVU120 (SEL120) selectively inhibits CDK8, resulting in decreased STAT5 and STAT1 phosphorylation and downstream signaling, and potentially leading to reduced tumor cell growth (PMID: 28422713). |
| DrugClasses | CDK8 Inhibitor 5 |
| CAS Registry Number | 1609522-33-9 |
| NCIT ID | C165747 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Ruxolitinib + RVU120 | RVU120 Ruxolitinib | 0 | 1 |
| RVU120 | RVU120 | 0 | 4 |
| RVU120 + Venetoclax | RVU120 Venetoclax | 0 | 1 |
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