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Starting April 21, you’ll be asked to log in or sign up for a free account after viewing 10 content pages each month.

Don’t worry—creating an account is quick and easy, and it comes with added benefits! Once logged in, you’ll not only continue accessing the content you already enjoy, but you’ll also unlock exclusive features like interactive donut plots for variant protein effects and variant impacts across the gene.

Stay tuned for these updates, and thank you for being part of our community!
Cancer Knowledgebase logo. White letters 'CKB' in light blue circle next to text Cancer Knowledgebase in black. Under this reads 'Powered by Genomenon' in dark blue text.

CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 50 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.

Basic Search
Explore by Gene Explore by Variant Explore by DrugClass - Available in CKB BOOST Explore by Drug - Available in CKB BOOST Explore by Indication/Tumor Type - Available in CKB BOOST
Advanced Search
Clinical Trial Search - Available in CKB BOOST Evidence Search - Available in CKB BOOST
News
Apr 14, 2025 - It's time for the quarterly update to the CKB CORE gene list! This quarter includes genes related to DNA repair. Also, check out the latest features now available in CORE by signing up for a free account! Have questions or comments? Email us at ckbsupport@genomenon.com. Thank you for all the support!
Mar 3, 2025 - Exciting news for our CKB CORE users! We have new features available in CORE! If you're interested in having access to these features, you can register for a free account here, and then login. Let us know if you have any questions and/or comments by emailing ckbsupport@genomenon.com.
Feb 12, 2025 - Interested in using the Advanced Search options in CKB, but not sure when and how to use them? Then check out this tutorial to learn how you can quickly identify potential treatments and appropriate clinical trials based on specific molecular criteria. Please feel free to reach out to us with any questions/comments or request a live demo! ckbsupport@genomenon.com 
Check out   CKB BOOST for content extending to 2100+ genes.
BOOST CORE
Genes
BOOST CORE
Gene Variants

Explore the Mastermind Genomic Intelligence Platform

Access article information on over 26 million variants, as well as curated germline variant content, and discover valuable gene and variant summary information to streamline your analysis and deepen your insights.

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