CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 50 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.
News
Oct 12, 2026
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It's time for the next quarterly update to the CORE gene list! This quarter we are highlighting the tumor suppressor genes. If you have any questions/comments, please feel free to reach out to us at ckbsupport@genomenon.com!
Jul 24, 2026
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We're excited to announce that CKB now has its own LinkedIn page! Follow us at https://www.linkedin.com/showcase/cancer-knowledgebase-ckb/ for updates on precision oncology, including variant interpretation, therapeutic evidence, clinical trials, and more! Thank you to our users for all your support and please feel free to reach out to us at ckbsupport@genomenon.com with any feedback and/or questions.
Explore the Mastermind Genomic Intelligence Platform
Access article information on over 26 million variants, as well as curated germline variant content,
and discover valuable gene and variant summary information to streamline your analysis and deepen your insights.
Comparison of CKB Offerings
KEY FEATURES
CKB BOOSTTM
Access 50 genes & related content
Access 2200+ genes & related content
Scalable & flexible content integration for 2200+ genes
Genes
(50 Genes)
(2200+ Genes)
Gene Variants
Therapies
Limited
Global Drug Approvals
Drug Classes
Limited
Clinical Trials
Limited
Efficacy Evidence
Variant Tier Coding
(AMP/CAP/ASCO)
(AMP/CAP/ASCO)
Advanced Search Capability
System Integration
More about our plans
The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a
select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via
gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2200
cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes
while enabling a robust browse-like feature when the desired content is unknown.
Downloadable data from CKB is available using the FLEX version. CKB FLEX delivers CKB content as a
flat file or JSON, enabling CKB data integration.
Visit
CKB BOOST
for more information.
Contact: ckbsupport@genomenon.com
CKB BOOST
for more information.
Contact: ckbsupport@genomenon.com