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| NCT ID | NCT00471497 |
| Title | A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) (ENESTnd) |
| Acronym | ENESTnd |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | SVK | POL | NOR | NLD | ITA | HUN | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CHE | CAN | BRA | BEL | AUT | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of California at Los Angeles Dept. of Hematology Clinic | Los Angeles | California | 90095 | United States | Details | |
| Kaiser Permanente - California Southern Dept of Kaiser South 3 | San Diego | California | 92120 | United States | Details | |
| Kaiser Permanente - California Northern Vallejo Med Center/Med Offices | Vallejo | California | 94589 | United States | Details | |
| Kaiser Permanente - California Northern Kaiser Med | Vallejo | California | 94609 | United States | Details | |
| Rocky Mountain Cancer Centers RMCC - Colorado Springs | Greenwood Village | Colorado | United States | Details | ||
| Florida Cancer Specialists Dept. FloridaCancerSpecialists | Fort Myers | Florida | 33901 | United States | Details | |
| Advanced Medical Specialties Research Dept. | Miami | Florida | 33176 | United States | Details | |
| Cancer Centers of Florida PA Cancer Centers of FL | Ocoee | Florida | 34761 | United States | Details | |
| Florida Retina Institute Flordia Cancer Affilates | Orlando | Florida | 32804 | United States | Details | |
| University of Chicago Section of Hematology/Oncology | Chicago | Illinois | 60637 | United States | Details | |
| Indiana Blood and Marrow Institute Dept. of Indiana Blood&Marrow | Beech Grove | Indiana | 46107 | United States | Details | |
| University of Iowa Hospitals and Clinics Dept.of U of Iowa Hosp&Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| Kansas City Cancer Center KCCC Business Office | Overland Park | Kansas | 66210 | United States | Details | |
| LSU HEALTH SCIENCES CENTER/ LSU SCHOOL OF MEDICINE Feist-Weiller Cancer Center | New Orleans | Louisiana | 70115 | United States | Details | |
| Michigan State University / Breslin Cancer Center Breslin Cancer Center | Lansing | Michigan | 48824 | United States | Details | |
| Missouri Cancer Associates Dept. of Boone Hospital Center | Columbia | Missouri | 65201 | United States | Details | |
| Hematology Oncology Consultants, Inc. Deptof Hem. Onc.Consunsultants | Saint Louis | Missouri | 63136 | United States | Details | |
| Hackensack University Medical Center Department of Research | Hackensack | New Jersey | 07601 | United States | Details | |
| Memorial Sloan Kettering Cancer Center Clinical Trials Office | New York | New York | 10021 | United States | Details | |
| University of North Carolina UNC Lineberger Cancer Center | Chapel Hill | North Carolina | 27514 | United States | Details | |
| Wake Forest University Health Sciences Dept. of Industry Research | Winston-Salem | North Carolina | 27157 | United States | Details | |
| University of Cincinnati / Barrett Cancer Center Dept.of Internal Med. | Cincinnati | Ohio | 45219 | United States | Details | |
| Cleveland Clinic Foundation CCF | Cleveland | Ohio | 44195 | United States | Details | |
| Northwest Cancer Specialists Compass Oncology -BKM | Portland | Oregon | 97210 | United States | Details | |
| Cancer Centers of the Carolinas CC of C -Eastside | Greenville | South Carolina | 29605 | United States | Details | |
| Chattanooga Oncology and Hematology Assoicates, PC Chattanooga Oncology | Chattanooga | Tennessee | 37404 | United States | Details | |
| Tennessee Oncology Dept. of Centennial Medical | Nashville | Tennessee | 37203 | United States | Details | |
| Texas Cancer Center ( Medical City Dallas Hospital) | Dallas | Texas | 75230 | United States | Details | |
| Cancer Care Centers of South Texas HOAST CCC of So.TX- Medical Center | San Antonio | Texas | 78229 | United States | Details | |
| Tyler Cancer Center | Tyler | Texas | 75702 | United States | Details | |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1221ADC | Argentina | Details | |
| Novartis Investigative Site | La Plata | Buenos Aires | B1902AVG | Argentina | Details | |
| Novartis Investigative Site | Salzburg | 5020 | Austria | Details | ||
| Novartis Investigative Site | Wien | A-1090 | Austria | Details | ||
| Novartis Investigative Site | Bruxelles | 1000 | Belgium | Details | ||
| Novartis Investigative Site | Charleroi | 6000 | Belgium | Details | ||
| Novartis Investigative Site | Gent | 9000 | Belgium | Details | ||
| Novartis Investigative Site | Leuven | 3000 | Belgium | Details | ||
| Novartis Investigative Site | Yvoir | 5530 | Belgium | Details | ||
| Novartis Investigative Site | Brasilia | DF | 70330-150 | Brazil | Details | |
| Novartis Investigative Site | Curitiba | PR | 80060-900 | Brazil | Details | |
| Novartis Investigative Site | Rio de Janeiro | RJ | 20211-030 | Brazil | Details | |
| Novartis Investigative Site | Campinas | SP | 13083-970 | Brazil | Details | |
| Novartis Investigative Site | Jau | SP | 17210-080 | Brazil | Details | |
| Novartis Investigative Site | Sao Paulo | SP | 05403 000 | Brazil | Details | |
| Novartis Investigative Site | São Paulo | SP | 01224-000 | Brazil | Details | |
| Novartis Investigative Site | São Paulo | SP | 01401-901 | Brazil | Details | |
| Novartis Investigative Site | Vancouver | British Columbia | V5Z 4E3 | Canada | Details | |
| Novartis Investigative Site | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Novartis Investigative Site | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Novartis Investigative Site | Quebec | G1J 1Z4 | Canada | Details | ||
| Novartis Investigative Site | Quebec | G1R 2J6 | Canada | Details | ||
| Novartis Investigative Site | Bogota | Cundinamarca | 110111 | Colombia | Details | |
| Novartis Investigative Site | Bogota | 110001 | Colombia | Details | ||
| Novartis Investigative Site | Praha 2 | Czech Republic | 128 20 | Czechia | Details | |
| Novartis Investigative Site | Olomouc | CZE | 775 20 | Czechia | Details | |
| Novartis Investigative Site | Copenhagen | DK-2100 | Denmark | Details | ||
| Novartis Investigative Site | Vejle | DK-7100 | Denmark | Details | ||
| Novartis Investigative Site | Cairo | Egypt | Details | |||
| Novartis Investigative Site | HUS Helsinki | FIN-00029 | Finland | Details | ||
| Novartis Investigative Site | Turku | FIN-20521 | Finland | Details | ||
| Novartis Investigative Site | Paris Cedex 10 | Cedex 10 | 75475 | France | Details | |
| Novartis Investigative Site | Caen | Cedex | 14033 | France | Details | |
| Novartis Investigative Site | Saint Priest en Jarez | Loire | 42270 | France | Details | |
| Novartis Investigative Site | Angers Cedex 1 | 49033 | France | Details | ||
| Novartis Investigative Site | Bordeaux | 33076 | France | Details | ||
| Novartis Investigative Site | Creteil | 94010 | France | Details | ||
| Novartis Investigative Site | Grenoble | 38043 | France | Details | ||
| Novartis Investigative Site | Lille | 59037 | France | Details | ||
| Novartis Investigative Site | Marseille | 13273 | France | Details | ||
| Novartis Investigative Site | Nantes | 44035 | France | Details | ||
| Novartis Investigative Site | Nice Cedex | 06202 | France | Details | ||
| Novartis Investigative Site | Pierre Benite Cedex | 69495 | France | Details | ||
| Novartis Investigative Site | Poitiers | 86000 | France | Details | ||
| Novartis Investigative Site | Rennes | 35019 | France | Details | ||
| Novartis Investigative Site | Toulouse | 31059 | France | Details | ||
| Novartis Investigative Site | Vandoeuvre les Nancy | 54511 | France | Details | ||
| Novartis Investigative Site | Mannheim | Baden-Wuerttemberg | 68305 | Germany | Details | |
| Novartis Investigative Site | Berlin | 13353 | Germany | Details | ||
| Novartis Investigative Site | Duesseldorf | 40225 | Germany | Details | ||
| Novartis Investigative Site | Eisenach | 99817 | Germany | Details | ||
| Novartis Investigative Site | Frankfurt | 60590 | Germany | Details | ||
| Novartis Investigative Site | Hamburg | 20246 | Germany | Details | ||
| Novartis Investigative Site | Kiel | 24105 | Germany | Details | ||
| Novartis Investigative Site | Koeln | 50937 | Germany | Details | ||
| Novartis Investigative Site | Leipzig | 04103 | Germany | Details | ||
| Novartis Investigative Site | Muenchen | 81675 | Germany | Details | ||
| Novartis Investigative Site | Ulm | 89081 | Germany | Details | ||
| Novartis Investigative Site | Hong Kong | Hong Kong | Details | |||
| Novartis Investigative Site | Budapest | 1097 | Hungary | Details | ||
| Novartis Investigative Site | Alessandria | AL | 15100 | Italy | Details | |
| Novartis Investigative Site | Ancona | AN | 60126 | Italy | Details | |
| Novartis Investigative Site | Bergamo | BG | 24127 | Italy | Details | |
| Novartis Investigative Site | Bologna | BO | 40138 | Italy | Details | |
| Novartis Investigative Site | Catania | CT | 95123 | Italy | Details | |
| Novartis Investigative Site | Firenze | FI | 50134 | Italy | Details | |
| Novartis Investigative Site | Genova | GE | 16132 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20162 | Italy | Details | |
| Novartis Investigative Site | Pescara | PE | 65124 | Italy | Details | |
| Novartis Investigative Site | Pisa | PI | 56126 | Italy | Details | |
| Novartis Investigative Site | Pavia | PV | 27100 | Italy | Details | |
| Novartis Investigative Site | Reggio Calabria | RC | 89124 | Italy | Details | |
| Novartis Investigative Site | Roma | RM | 00133 | Italy | Details | |
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| Novartis Investigative Site | Roma | RM | 00161 | Italy | Details | |
| Novartis Investigative Site | Siena | SI | 53100 | Italy | Details | |
| Novartis Investigative Site | Udine | UD | 33100 | Italy | Details | |
| Novartis Investigative Site | Napoli | 80131 | Italy | Details | ||
| Novartis Investigative Site | Napoli | 80132 | Italy | Details | ||
| Novartis Investigative Site | Perugia | 06129 | Italy | Details | ||
| Novartis Investigative Site | Nagoya | Aichi | 453-8511 | Japan | Details | |
| Novartis Investigative Site | Nagoya | Aichi | 466 8560 | Japan | Details | |
| Novartis Investigative Site | Maebashi city | Gunma | 371 8511 | Japan | Details | |
| Novartis Investigative Site | Maebashi | Gunma | 371-0821 | Japan | Details | |
| Novartis Investigative Site | Sapporo city | Hokkaido | 060 8648 | Japan | Details | |
| Novartis Investigative Site | Sapporo | Hokkaido | 003-0006 | Japan | Details | |
| Novartis Investigative Site | Nishinomiya | Hyogo | 663 8501 | Japan | Details | |
| Novartis Investigative Site | Tsukuba city | Ibaraki | 305-8576 | Japan | Details | |
| Novartis Investigative Site | Kanazawa-city | Ishikawa | 920-8641 | Japan | Details | |
| Novartis Investigative Site | Kumamoto City | Kumamoto | 860-8556 | Japan | Details | |
| Novartis Investigative Site | Tsu-city | Mie | 514-8507 | Japan | Details | |
| Novartis Investigative Site | Nagasaki-city | Nagasaki | 852-8501 | Japan | Details | |
| Novartis Investigative Site | Osaka Sayama | Osaka | 589 8511 | Japan | Details | |
| Novartis Investigative Site | Suita city | Osaka | 565 0871 | Japan | Details | |
| Novartis Investigative Site | Hidaka-city | Saitama | 350-1298 | Japan | Details | |
| Novartis Investigative Site | Hamamatsu-city | Shizuoka | 431-3192 | Japan | Details | |
| Novartis Investigative Site | Shimotsuke | Tochigi | 329-0498 | Japan | Details | |
| Novartis Investigative Site | Bunkyo ku | Tokyo | 113 8655 | Japan | Details | |
| Novartis Investigative Site | Bunkyo-ku | Tokyo | 113-8519 | Japan | Details | |
| Novartis Investigative Site | Chuo ku | Tokyo | 104 0045 | Japan | Details | |
| Novartis Investigative Site | Shinagawa ku | Tokyo | 141 8625 | Japan | Details | |
| Novartis Investigative Site | Shinjuku-ku | Tokyo | 160 8582 | Japan | Details | |
| Novartis Investigative Site | Shinjuku-ku | Tokyo | 160-0023 | Japan | Details | |
| Novartis Investigative Site | Akita | 010-8543 | Japan | Details | ||
| Novartis Investigative Site | Chiba | 260 8677 | Japan | Details | ||
| Novartis Investigative Site | Hiroshima | 734-8551 | Japan | Details | ||
| Novartis Investigative Site | Niigata | 951 8520 | Japan | Details | ||
| Novartis Investigative Site | Osaka | 545-8586 | Japan | Details | ||
| Novartis Investigative Site | Saitama | 330 8503 | Japan | Details | ||
| Novartis Investigative Site | Seoul | Korea | 05505 | Korea, Republic of | Details | |
| Novartis Investigative Site | Seoul | Seocho Gu | 06591 | Korea, Republic of | Details | |
| Novartis Investigative Site | Jeollanam-do | 519763 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Taegu | 41944 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Selangor | 68000 | Malaysia | Details | ||
| Novartis Investigative Site | Mexico | Distrito Federal | 06726 | Mexico | Details | |
| Novartis Investigative Site | Monterrey | Nuevo Leon | 64460 | Mexico | Details | |
| Novartis Investigative Site | Amsterdam | 1081 HV | Netherlands | Details | ||
| Novartis Investigative Site | Oslo | NO-0310 | Norway | Details | ||
| Novartis Investigative Site | Trondheim | 7006 | Norway | Details | ||
| Novartis Investigative Site | Katowice | 40032 | Poland | Details | ||
| Novartis Investigative Site | Lublin | 20-081 | Poland | Details | ||
| Novartis Investigative Site | Rzeszow | 35 055 | Poland | Details | ||
| Novartis Investigative Site | Warszawa | 02-097 | Poland | Details | ||
| Novartis Investigative Site | Wroclaw | 50-367 | Poland | Details | ||
| Novartis Investigative Site | Moscow | 125167 | Russian Federation | Details | ||
| Novartis Investigative Site | Novosibirsk | 630051 | Russian Federation | Details | ||
| Novartis Investigative Site | Saint Petersburg | 197022 | Russian Federation | Details | ||
| Novartis Investigative Site | Singapore | 119228 | Singapore | Details | ||
| Novartis Investigative Site | Singapore | 169608 | Singapore | Details | ||
| Novartis Investigative Site | Bratislava | Slovak Republic | 833 10 | Slovakia | Details | |
| Novartis Investigative Site | Bratislava | 85107 | Slovakia | Details | ||
| Novartis Investigative Site | Bloemfontein | 9301 | South Africa | Details | ||
| Novartis Investigative Site | Cape Town | 7925 | South Africa | Details | ||
| Novartis Investigative Site | Parktown | 2193 | South Africa | Details | ||
| Novartis Investigative Site | Pretoria | 0001 | South Africa | Details | ||
| Novartis Investigative Site | Pretoria | 0027 | South Africa | Details | ||
| Novartis Investigative Site | Elche | Alicante | 03203 | Spain | Details | |
| Novartis Investigative Site | Granada | Andalucia | 18014 | Spain | Details | |
| Novartis Investigative Site | Malaga | Andalucia | 29010 | Spain | Details | |
| Novartis Investigative Site | Santander | Cantabria | 39008 | Spain | Details | |
| Novartis Investigative Site | Salamanca | Castilla Y Leon | 37007 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Catalunya | 08035 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Catalunya | 08036 | Spain | Details | |
| Novartis Investigative Site | Hospitalet de LLobregat | Catalunya | 08907 | Spain | Details | |
| Novartis Investigative Site | Valencia | Comunidad Valenciana | 46010 | Spain | Details | |
| Novartis Investigative Site | La Coruna | Galicia | 15006 | Spain | Details | |
| Novartis Investigative Site | Santiago de Compostela | Galicia | 15706 | Spain | Details | |
| Novartis Investigative Site | Bilbao | Pais Vasco | 48013 | Spain | Details | |
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| Novartis Investigative Site | La Laguna | Santa Cruz De Tenerife | 38320 | Spain | Details | |
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| Novartis Investigative Site | Zaragoza | 50009 | Spain | Details | ||
| Novartis Investigative Site | Göteborg | SE-413 45 | Sweden | Details | ||
| Novartis Investigative Site | Huddinge | SE-14186 | Sweden | Details | ||
| Novartis Investigative Site | Lulea | SE 971 80 | Sweden | Details | ||
| Novartis Investigative Site | Lund | SE-221 85 | Sweden | Details | ||
| Novartis Investigative Site | Orebro | SE-701 85 | Sweden | Details | ||
| Novartis Investigative Site | Stockholm | SE-171 76 | Sweden | Details | ||
| Novartis Investigative Site | Sundsvall | SE-851 86 | Sweden | Details | ||
| Novartis Investigative Site | Umeå | SE-901 85 | Sweden | Details | ||
| Novartis Investigative Site | Uppsala | SE-751 85 | Sweden | Details | ||
| Novartis Investigative Site | Geneve | 1205 | Switzerland | Details | ||
| Novartis Investigative Site | Kaohsiung City | 83301 | Taiwan | Details | ||
| Novartis Investigative Site | Taipei | 10002 | Taiwan | Details | ||
| Novartis Investigative Site | Taoyuan | 33305 | Taiwan | Details | ||
| Novartis Investigative Site | Bangkok | 10330 | Thailand | Details | ||
| Novartis Investigative Site | Bangkok | 10400 | Thailand | Details | ||
| Novartis Investigative Site | Bangkok | 10700 | Thailand | Details | ||
| Novartis Investigative Site | Istanbul | TUR | 34098 | Turkey | Details | |
| Novartis Investigative Site | Adana | 01330 | Turkey | Details | ||
| Novartis Investigative Site | Ankara | 06500 | Turkey | Details | ||
| Novartis Investigative Site | Izmir | 35340 | Turkey | Details | ||
| Novartis Investigative Site | Glasgow | G12 OYN | United Kingdom | Details | ||
| Novartis Investigative Site | Leeds | LS9 7TF | United Kingdom | Details | ||
| Novartis Investigative Site | Liverpool | L7 8XP | United Kingdom | Details | ||
| Novartis Investigative Site | London | W12 0HS | United Kingdom | Details | ||
| Novartis Investigative Site | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Novartis Investigative Site | Caracas | Distrito Capital | 1010 | Venezuela | Details |