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| NCT ID | NCT01682083 |
| Title | Dabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD). (COMBI-AD) |
| Acronym | COMBI-AD |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | POL | NZL | NOR | NLD | ITA | ISR | GRC | GBR | FRA | ESP | DNK | DEU | CZE | CHE | CAN | BRA | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Novartis Investigative Site | Birmingham | Alabama | 35243 | United States | Details | |
| Novartis Investigative Site | Tucson | Arizona | 85719 | United States | Details | |
| Novartis Investigative Site | San Francisco | California | 94115 | United States | Details | |
| Novartis Investigative Site | San Francisco | California | 94143 | United States | Details | |
| Novartis Investigative Site | Aurora | Colorado | 80045 | United States | Details | |
| Novartis Investigative Site | Farmington | Connecticut | 06030 | United States | Details | |
| Novartis Investigative Site | Fort Myers | Florida | 33916 | United States | Details | |
| Novartis Investigative Site | Lake Worth | Florida | 33461 | United States | Details | |
| Novartis Investigative Site | Orlando | Florida | 32806 | United States | Details | |
| Novartis Investigative Site | Saint Petersburg | Florida | 33705 | United States | Details | |
| Novartis Investigative Site | Stuart | Florida | 34994 | United States | Details | |
| Novartis Investigative Site | Tampa | Florida | 33612 | United States | Details | |
| Novartis Investigative Site | Atlanta | Georgia | 30322 | United States | Details | |
| Novartis Investigative Site | Atlanta | Georgia | 30341 | United States | Details | |
| Novartis Investigative Site | Indianapolis | Indiana | 46202 | United States | Details | |
| Novartis Investigative Site | Baltimore | Maryland | 21237 | United States | Details | |
| Novartis Investigative Site | Lutherville-Timonium | Maryland | 21093 | United States | Details | |
| Novartis Investigative Site | Boston | Massachusetts | 02114 | United States | Details | |
| Novartis Investigative Site | Ann Arbor | Michigan | 48019 | United States | Details | |
| Novartis Investigative Site | Morristown | New Jersey | 07960 | United States | Details | |
| Novartis Investigative Site | Winston-Salem | North Carolina | 27157 | United States | Details | |
| Novartis Investigative Site | Cincinnati | Ohio | 45242 | United States | Details | |
| Novartis Investigative Site | Columbus | Ohio | 43210 | United States | Details | |
| Novartis Investigative Site | Portland | Oregon | 97213 | United States | Details | |
| Novartis Investigative Site | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Novartis Investigative Site | Nashville | Tennessee | 37203 | United States | Details | |
| Novartis Investigative Site | Nashville | Tennessee | 37232-5536 | United States | Details | |
| Novartis Investigative Site | Dallas | Texas | 75230 | United States | Details | |
| Novartis Investigative Site | Murray | Utah | 84107 | United States | Details | |
| Novartis Investigative Site | Seattle | Washington | 98109 | United States | Details | |
| Novartis Investigative Site | Capital Federal | Buenos Aires | C1426ANZ | Argentina | Details | |
| Novartis Investigative Site | Ciudad Autonoma de Buenos Aires | Buenos Aires | C1050AAK | Argentina | Details | |
| Novartis Investigative Site | Viedma | Río Negro | R8500ACE | Argentina | Details | |
| Novartis Investigative Site | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Novartis Investigative Site | Ciudad Autonoma de Buenos Aires | C1025ABH | Argentina | Details | ||
| Novartis Investigative Site | Ciudad Autonoma de Buenos Aires | C1121ABE | Argentina | Details | ||
| Novartis Investigative Site | Santa Fe | 3000 | Argentina | Details | ||
| Novartis Investigative Site | Gateshead | New South Wales | 2290 | Australia | Details | |
| Novartis Investigative Site | North Sydney | New South Wales | 2060 | Australia | Details | |
| Novartis Investigative Site | Tweed Heads | New South Wales | 2485 | Australia | Details | |
| Novartis Investigative Site | Westmead | New South Wales | 2145 | Australia | Details | |
| Novartis Investigative Site | Greenslopes | Queensland | 4120 | Australia | Details | |
| Novartis Investigative Site | Milton | Queensland | 4064 | Australia | Details | |
| Novartis Investigative Site | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Novartis Investigative Site | Adelaide | South Australia | 5000 | Australia | Details | |
| Novartis Investigative Site | Box Hill | Victoria | 3128 | Australia | Details | |
| Novartis Investigative Site | Heidelberg | Victoria | 3084 | Australia | Details | |
| Novartis Investigative Site | Melbourne | Victoria | 3004 | Australia | Details | |
| Novartis Investigative Site | Nedlands | Western Australia | 6009 | Australia | Details | |
| Novartis Investigative Site | Graz | 8036 | Austria | Details | ||
| Novartis Investigative Site | Innsbruck | 6020 | Austria | Details | ||
| Novartis Investigative Site | Linz | A-4010 | Austria | Details | ||
| Novartis Investigative Site | Salzburg | A-5020 | Austria | Details | ||
| Novartis Investigative Site | Wels | A-4600 | Austria | Details | ||
| Novartis Investigative Site | Wien | 1090 | Austria | Details | ||
| Novartis Investigative Site | Wien | A-1030 | Austria | Details | ||
| Novartis Investigative Site | Wien | A-1220 | Austria | Details | ||
| Novartis Investigative Site | Brussels | 1200 | Belgium | Details | ||
| Novartis Investigative Site | Leuven | 3000 | Belgium | Details | ||
| Novartis Investigative Site | Liege | 4000 | Belgium | Details | ||
| Novartis Investigative Site | Wilrijk | 2610 | Belgium | Details | ||
| Novartis Investigative Site | Goiania | Goiás | 74605-030 | Brazil | Details | |
| Novartis Investigative Site | Curitiba | Paraná | 81520-060 | Brazil | Details | |
| Novartis Investigative Site | Ijui | Rio Grande Do Sul | 98700-000 | Brazil | Details | |
| Novartis Investigative Site | Rio De Janeiro | 22 260-020 | Brazil | Details | ||
| Novartis Investigative Site | São Paulo | 01323-900 | Brazil | Details | ||
| Novartis Investigative Site | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Novartis Investigative Site | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| Novartis Investigative Site | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| Novartis Investigative Site | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Novartis Investigative Site | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Novartis Investigative Site | Montreal | Quebec | H2W 1S6 | Canada | Details | |
| Novartis Investigative Site | Quebec | G1R 2J6 | Canada | Details | ||
| Novartis Investigative Site | Brno | 656 53 | Czechia | Details | ||
| Novartis Investigative Site | Hradec Kralove | 500 05 | Czechia | Details | ||
| Novartis Investigative Site | Olomouc | 775 20 | Czechia | Details | ||
| Novartis Investigative Site | Praha 10 | 100 34 | Czechia | Details | ||
| Novartis Investigative Site | Praha 2 | 128 08 | Czechia | Details | ||
| Novartis Investigative Site | Zlin | 76275 | Czechia | Details | ||
| Novartis Investigative Site | Arhus C | 8000 | Denmark | Details | ||
| Novartis Investigative Site | Herlev | 2730 | Denmark | Details | ||
| Novartis Investigative Site | Odense | 5000 C | Denmark | Details | ||
| Novartis Investigative Site | Bordeaux | 33075 | France | Details | ||
| Novartis Investigative Site | Boulogne-Billancourt | 92100 | France | Details | ||
| Novartis Investigative Site | Brest cedex | 29609 | France | Details | ||
| Novartis Investigative Site | Dijon | 21079 | France | Details | ||
| Novartis Investigative Site | Grenoble | 38043 | France | Details | ||
| Novartis Investigative Site | Lille | 59037 | France | Details | ||
| Novartis Investigative Site | Marseille cedex 5 | 13385 | France | Details | ||
| Novartis Investigative Site | Montpellier cedex 5 | 34295 | France | Details | ||
| Novartis Investigative Site | Nice | 06202 | France | Details | ||
| Novartis Investigative Site | Paris Cedex 10 | 75475 | France | Details | ||
| Novartis Investigative Site | Paris | 75006 | France | Details | ||
| Novartis Investigative Site | Pierre-Benite cedex | 69495 | France | Details | ||
| Novartis Investigative Site | Reims Cedex | 51092 | France | Details | ||
| Novartis Investigative Site | Rennes Cedex | 35042 | France | Details | ||
| Novartis Investigative Site | Toulouse cedex 9 | 31059 | France | Details | ||
| Novartis Investigative Site | Tours Cedex 9 | 37044 | France | Details | ||
| Novartis Investigative Site | Villejuif cedex | 94805 | France | Details | ||
| Novartis Investigative Site | Freiburg | Baden-Wuerttemberg | 79104 | Germany | Details | |
| Novartis Investigative Site | Heidelberg | Baden-Wuerttemberg | 69120 | Germany | Details | |
| Novartis Investigative Site | Heilbronn | Baden-Wuerttemberg | 74078 | Germany | Details | |
| Novartis Investigative Site | Mannheim | Baden-Wuerttemberg | 68167 | Germany | Details | |
| Novartis Investigative Site | Tuebingen | Baden-Wuerttemberg | 72076 | Germany | Details | |
| Novartis Investigative Site | Ulm | Baden-Wuerttemberg | 89081 | Germany | Details | |
| Novartis Investigative Site | Muenchen | Bayern | 80337 | Germany | Details | |
| Novartis Investigative Site | Muenchen | Bayern | 80804 | Germany | Details | |
| Novartis Investigative Site | Nuernberg | Bayern | 90419 | Germany | Details | |
| Novartis Investigative Site | Regensburg | Bayern | 93053 | Germany | Details | |
| Novartis Investigative Site | Wuerzburg | Bayern | 97080 | Germany | Details | |
| Novartis Investigative Site | Darmstadt | Hessen | 64297 | Germany | Details | |
| Novartis Investigative Site | Kassel | Hessen | 34125 | Germany | Details | |
| Novartis Investigative Site | Marburg | Hessen | 35043 | Germany | Details | |
| Novartis Investigative Site | Wiesbaden | Hessen | 65199 | Germany | Details | |
| Novartis Investigative Site | Schwerin | Mecklenburg-Vorpommern | 19049 | Germany | Details | |
| Novartis Investigative Site | Buxtehude | Niedersachsen | 21614 | Germany | Details | |
| Novartis Investigative Site | Hannover | Niedersachsen | 30625 | Germany | Details | |
| Novartis Investigative Site | Aachen | Nordrhein-Westfalen | 52074 | Germany | Details | |
| Novartis Investigative Site | Bochum | Nordrhein-Westfalen | 44791 | Germany | Details | |
| Novartis Investigative Site | Bonn | Nordrhein-Westfalen | 53127 | Germany | Details | |
| Novartis Investigative Site | Essen | Nordrhein-Westfalen | 45122 | Germany | Details | |
| Novartis Investigative Site | Koeln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| Novartis Investigative Site | Muenster | Nordrhein-Westfalen | 48149 | Germany | Details | |
| Novartis Investigative Site | Mainz | Rheinland-Pfalz | 55131 | Germany | Details | |
| Novartis Investigative Site | Homburg | Saarland | 66421 | Germany | Details | |
| Novartis Investigative Site | Magdeburg | Sachsen-Anhalt | 39120 | Germany | Details | |
| Novartis Investigative Site | Quedlinburg | Sachsen-Anhalt | 06484 | Germany | Details | |
| Novartis Investigative Site | Kiel | Schleswig-Holstein | 24105 | Germany | Details | |
| Novartis Investigative Site | Luebeck | Schleswig-Holstein | 23538 | Germany | Details | |
| Novartis Investigative Site | Erfurt | Thueringen | 99089 | Germany | Details | |
| Novartis Investigative Site | Gera | Thueringen | 07548 | Germany | Details | |
| Novartis Investigative Site | Berlin | 10117 | Germany | Details | ||
| Novartis Investigative Site | Berlin | 10249 | Germany | Details | ||
| Novartis Investigative Site | Berlin | 13585 | Germany | Details | ||
| Novartis Investigative Site | Athens | 11527 | Greece | Details | ||
| Novartis Investigative Site | Thessaloniki | 54622 | Greece | Details | ||
| Novartis Investigative Site | Thessaloniki | 564 29 | Greece | Details | ||
| Novartis Investigative Site | Jerusalem | 91120 | Israel | Details | ||
| Novartis Investigative Site | Ramat Gan | 52621 | Israel | Details | ||
| Novartis Investigative Site | Roma | Lazio | 00167 | Italy | Details | |
| Novartis Investigative Site | Genova | Liguria | 16132 | Italy | Details | |
| Novartis Investigative Site | Bergamo | Lombardia | 24127 | Italy | Details | |
| Novartis Investigative Site | Milano | Lombardia | 20133 | Italy | Details | |
| Novartis Investigative Site | Milano | Lombardia | 20141 | Italy | Details | |
| Novartis Investigative Site | Candiolo | Piemonte | 10060 | Italy | Details | |
| Novartis Investigative Site | Pisa | Toscana | 56126 | Italy | Details | |
| Novartis Investigative Site | Padova | Veneto | 35128 | Italy | Details | |
| Novartis Investigative Site | Shizuoka | 411-8777 | Japan | Details | ||
| Novartis Investigative Site | Tokyo | 104-0045 | Japan | Details | ||
| Novartis Investigative Site | Amsterdam | 1066 CX | Netherlands | Details | ||
| Novartis Investigative Site | Amsterdam | 1081 HV | Netherlands | Details | ||
| Novartis Investigative Site | Groningen | 9713 GZ | Netherlands | Details | ||
| Novartis Investigative Site | Leeuwarden | 8934 AD | Netherlands | Details | ||
| Novartis Investigative Site | Maastricht | 6229 HX | Netherlands | Details | ||
| Novartis Investigative Site | Nijmegen | 6525 GA | Netherlands | Details | ||
| Novartis Investigative Site | Rotterdam | 3015 GD | Netherlands | Details | ||
| Novartis Investigative Site | Auckland | 0622 | New Zealand | Details | ||
| Novartis Investigative Site | Alesund | 6026 | Norway | Details | ||
| Novartis Investigative Site | Oslo | 0310 | Norway | Details | ||
| Novartis Investigative Site | Gdansk | 80-215 | Poland | Details | ||
| Novartis Investigative Site | Konin | 62-500 | Poland | Details | ||
| Novartis Investigative Site | Poznan | 60-693 | Poland | Details | ||
| Novartis Investigative Site | Warszawa | 02-781 | Poland | Details | ||
| Novartis Investigative Site | Warszawa | 04-125 | Poland | Details | ||
| Novartis Investigative Site | Chelyabinsk | 454087 | Russian Federation | Details | ||
| Novartis Investigative Site | Moscow | 115478 | Russian Federation | Details | ||
| Novartis Investigative Site | Moscow | 143423 | Russian Federation | Details | ||
| Novartis Investigative Site | Ryazan | 390011 | Russian Federation | Details | ||
| Novartis Investigative Site | St. Petersburg | 191104 | Russian Federation | Details | ||
| Novartis Investigative Site | St. Petersburg | 197758 | Russian Federation | Details | ||
| Novartis Investigative Site | St. Petersburg | Russian Federation | Details | |||
| Novartis Investigative Site | Volgograd | 400138 | Russian Federation | Details | ||
| Novartis Investigative Site | Badalona | 08916 | Spain | Details | ||
| Novartis Investigative Site | Barcelona | 08035 | Spain | Details | ||
| Novartis Investigative Site | Barcelona | 08036 | Spain | Details | ||
| Novartis Investigative Site | Cartagena | 30202 | Spain | Details | ||
| Novartis Investigative Site | Las Palmas De Gran Canaria | 35016 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28034 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28041 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28046 | Spain | Details | ||
| Novartis Investigative Site | Malaga | 29010 | Spain | Details | ||
| Novartis Investigative Site | Palma de Mallorca | 07198 | Spain | Details | ||
| Novartis Investigative Site | Pamplona | 31008 | Spain | Details | ||
| Novartis Investigative Site | San Sebastian | 20014 | Spain | Details | ||
| Novartis Investigative Site | Santander | 39008 | Spain | Details | ||
| Novartis Investigative Site | Sevilla | 41014 | Spain | Details | ||
| Novartis Investigative Site | Valencia | 46014 | Spain | Details | ||
| Novartis Investigative Site | Goteborg | SE-413 45 | Sweden | Details | ||
| Novartis Investigative Site | Lund | SE-221 85 | Sweden | Details | ||
| Novartis Investigative Site | Stockholm | SE-171 76 | Sweden | Details | ||
| Novartis Investigative Site | Uppsala | SE-751 85 | Sweden | Details | ||
| Novartis Investigative Site | Basel | 4031 | Switzerland | Details | ||
| Novartis Investigative Site | Chur | 7000 | Switzerland | Details | ||
| Novartis Investigative Site | Zurich | 8091 | Switzerland | Details | ||
| Novartis Investigative Site | Taichung | 404 | Taiwan | Details | ||
| Novartis Investigative Site | Taipei | 100 | Taiwan | Details | ||
| Novartis Investigative Site | Taoyuan | 333 | Taiwan | Details | ||
| Novartis Investigative Site | Northwood | Middlesex | HA6 2RN | United Kingdom | Details | |
| Novartis Investigative Site | Exeter | EX2 5DW | United Kingdom | Details | ||
| Novartis Investigative Site | Glasgow | G12 0YN | United Kingdom | Details | ||
| Novartis Investigative Site | Guildford | GU2 7XX | United Kingdom | Details | ||
| Novartis Investigative Site | Leeds | LS9 7TF | United Kingdom | Details | ||
| Novartis Investigative Site | London | NW3 2QG | United Kingdom | Details | ||
| Novartis Investigative Site | London | SW3 6JJ | United Kingdom | Details | ||
| Novartis Investigative Site | London | W1G 6AD | United Kingdom | Details | ||
| Novartis Investigative Site | Manchester | M20 4BX | United Kingdom | Details | ||
| Novartis Investigative Site | Newcastle upon Tyne | NE7 7DN | United Kingdom | Details | ||
| Novartis Investigative Site | Norwich | NR4 7UY | United Kingdom | Details | ||
| Novartis Investigative Site | Preston | PR2 9HT | United Kingdom | Details | ||
| Novartis Investigative Site | Southampton | SO16 6YD | United Kingdom | Details |