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| NCT ID | NCT01698918 |
| Title | Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer |
| Acronym | BOLERO-4 |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | TUR | NLD | HUN | GBR | FRA | ESP | BRA | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center SC-2 | Birmingham | Alabama | 35294 | United States | Details | |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | United States | Details | |
| Loma Linda University Loma Linda | Loma Linda | California | 92354 | United States | Details | |
| Breastlink Medical Group Dept. of BreastlinkResearchGrp | Long Beach | California | 90806 | United States | Details | |
| Oncology Specialists, SC Advocate Medical Group-Niles | Park Ridge | Illinois | 60068-0736 | United States | Details | |
| St. Francis Health Comprehensive Cancer Center | Topeka | Kansas | 66606-169 | United States | Details | |
| Norton Healthcare Inc SC | Louisville | Kentucky | 40202 | United States | Details | |
| Baystate Medical Center SC-2 | Springfield | Massachusetts | 01199 | United States | Details | |
| Saint Barnabas Medical Center CancerCenter of Saint Barnabas | Livingston | New Jersey | 07039 | United States | Details | |
| University of New Mexico Hospital SC | Albuquerque | New Mexico | 87106 | United States | Details | |
| Broome Oncology SC | Johnson City | New York | 13790 | United States | Details | |
| Columbia University Medical Center- New York Presbyterian Columbia | New York | New York | 10032 | United States | Details | |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | United States | Details | |
| East Texas Hematology Clinic SC | Lufkin | Texas | 75904 | United States | Details | |
| Utah Cancer Specialists Dept.of Utah Cancer Spec. (3) | Salt Lake City | Utah | 84106 | United States | Details | |
| Novartis Investigative Site | Santa Rosa | La Pampa | 6300 | Argentina | Details | |
| Novartis Investigative Site | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Novartis Investigative Site | Porto Alegre | RS | 90035-003 | Brazil | Details | |
| Novartis Investigative Site | Sao Paulo | SP | 01317-002 | Brazil | Details | |
| Novartis Investigative Site | Sao Paulo | SP | 04014-002 | Brazil | Details | |
| Novartis Investigative Site | Besancon cedex | 25030 | France | Details | ||
| Novartis Investigative Site | Bordeaux | 33076 | France | Details | ||
| Novartis Investigative Site | Hyères | 83400 | France | Details | ||
| Novartis Investigative Site | Le Chesnay | 78157 | France | Details | ||
| Novartis Investigative Site | Lyon | 69373 | France | Details | ||
| Novartis Investigative Site | Nancy | 54000 | France | Details | ||
| Novartis Investigative Site | Nantes Cedex | 44277 | France | Details | ||
| Novartis Investigative Site | Kecskemet | Bacs Kiskun | 6000 | Hungary | Details | |
| Novartis Investigative Site | Gyula | 5700 | Hungary | Details | ||
| Novartis Investigative Site | Szekszard | 7100 | Hungary | Details | ||
| Novartis Investigative Site | Nagoya-city | Aichi | 467-8602 | Japan | Details | |
| Novartis Investigative Site | Sapporo-city | Hokkaido | 003-0804 | Japan | Details | |
| Novartis Investigative Site | Shiwa-gun | Iwate | 028-3695 | Japan | Details | |
| Novartis Investigative Site | Kawasaki-city | Kanagawa | 216-8511 | Japan | Details | |
| Novartis Investigative Site | Kumamoto City | Kumamoto | 860-8556 | Japan | Details | |
| Novartis Investigative Site | Seoul | 01812 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 06273 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Maastricht | AZ | 5800 | Netherlands | Details | |
| Novartis Investigative Site | Lisboa | 1400-038 | Portugal | Details | ||
| Novartis Investigative Site | Lisboa | 1649-035 | Portugal | Details | ||
| Novartis Investigative Site | Porto | 4200-072 | Portugal | Details | ||
| Novartis Investigative Site | Salamanca | Castilla Y Leon | 37007 | Spain | Details | |
| Novartis Investigative Site | Valencia | Comunidad Valenciana | 46010 | Spain | Details | |
| Novartis Investigative Site | La Coruna | Galicia | 15006 | Spain | Details | |
| Novartis Investigative Site | Bangkok | 10330 | Thailand | Details | ||
| Novartis Investigative Site | Bangkok | 10400 | Thailand | Details | ||
| Novartis Investigative Site | Bangkok | 10700 | Thailand | Details | ||
| Novartis Investigative Site | Antalya | 07059 | Turkey | Details | ||
| Novartis Investigative Site | Istanbul | 34303 | Turkey | Details | ||
| Novartis Investigative Site | Izmir | 35040 | Turkey | Details | ||
| Novartis Investigative Site | Bath | BA1 3NG | United Kingdom | Details |