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| NCT ID | NCT01774786 |
| Title | A Study of Perjeta (Pertuzumab) in Combination With Herceptin (Trastuzumab) and Chemotherapy in Patients With HER2-Positive Metastatic Gastroesophageal Junction or Gastric Cancer |
| Acronym | JACOB |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | TUR | ROU | POL | NLD | ITA | HUN | HRV | FIN | ESP | DEU | CHE | CAN | BRA | BGR | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Florida Cancer Specialists - SCRI; Pharmacy | Fort Myers | Florida | 33901 | United States | Details | |
| University Of Chicago Medical Center; Section Of Hematology/Oncology | Chicago | Illinois | 60637 | United States | Details | |
| Indiana University Health; Goshen Center for Cancer Care | Goshen | Indiana | 46526 | United States | Details | |
| Comprehensive Cancer Centers of Nevada - Eastern Avenue | Las Vegas | Nevada | 89169 | United States | Details | |
| New York Oncology Hematology, P.C. | Albany | New York | 12206 | United States | Details | |
| Queens Medical Associates | Fresh Meadows | New York | 11366 | United States | Details | |
| Weill Medical College of Cornell University; Division of Hematology & Medical Oncology | New York | New York | 10065 | United States | Details | |
| Oncology Hematology Care | Cincinnati | Ohio | 45219 | United States | Details | |
| Medical University of South Carolina; Hollings Cancer Center | Charleston | South Carolina | 29425 | United States | Details | |
| Tennessee Oncology PLLC - Nashville (20th Ave) | Nashville | Tennessee | 37203 | United States | Details | |
| Royal Brisbane Womens Hosp; Division of Oncology | Herston | Queensland | 4029 | Australia | Details | |
| Monash Medical Centre; Oncology | Clayton | Victoria | 3168 | Australia | Details | |
| Austin Health; Cancer Clinical Trial Centre | Heidelberg | Victoria | 3084 | Australia | Details | |
| Sir Charles Gairdner Hospital; Medical Oncology | Perth | Western Australia | 6009 | Australia | Details | |
| Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt. | Salzburg | 5020 | Austria | Details | ||
| Krankenhaus St. Vinzenz Der Barmherzigen Schwestern Zams; Abt. Für Innere Medizin | Zams | 6511 | Austria | Details | ||
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| Clinicas Oncologicas Integradas - COI | Rio De Janeiro | RJ | 22290-160 | Brazil | Details | |
| Hospital Nossa Senhora da Conceicao | Porto Alegre | RS | 91350-200 | Brazil | Details | |
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | Brazil | Details | ||
| Centro de Pesquisas Oncologicas - CEPON | Florianopolis | SC | 88034-000 | Brazil | Details | |
| Hospital Sirio Libanes; Centro de Oncologia | Sao Paulo | SP | 01308-050 | Brazil | Details | |
| Clinica de Oncologia Medica | Sao Paulo | SP | 01406100 | Brazil | Details | |
| Hospital A. C. Camargo; Oncologia | Sao Paulo | SP | 01509-010 | Brazil | Details | |
| Universidade Federal de Sao Paulo - UNIFESP*X | Sao Paulo | SP | 22793-080 | Brazil | Details | |
| Complex Oncological Center - Plovdiv, EOOD | Plovdiv | 4004 | Bulgaria | Details | ||
| MHAT Serdika | Sofia | 1301 | Bulgaria | Details | ||
| SHATOD Dr. Marko Antonov Markov-Varna, EOOD; Department of Medicinall Onchotherapy and Palliative | Varna | 9010 | Bulgaria | Details | ||
| Hamilton Health Sciences - Juravinski Cancer Centre | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| London Regional Cancer Centre | London | Ontario | N6A 4L6 | Canada | Details | |
| Health Sciences North | Sudbury | Ontario | P3E 5J1 | Canada | Details | |
| Toronto East General Hospital; Haematology/Oncology | Toronto | Ontario | M4C 3E7 | Canada | Details | |
| Sunnybrook Health Science Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Mount Sinai Hospital; Oncology | Toronto | Ontario | M5G 1X5 | Canada | Details | |
| McGill University; Glen Site; Oncology | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Cancer Hospital Chinese Academy of Medical Sciences. | Beijing | 100021 | China | Details | ||
| The Affiliated Hospital of Military Medical Sciences(The 307th Hospital of Chinese PLA) | Beijing | 100071 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| the First Hospital of Jilin University | Changchun | 130021 | China | Details | ||
| Jilin Cancer Hospital | Changchun | 132013 | China | Details | ||
| Changzhou First People's Hospital | Changzhou | 213003 | China | Details | ||
| Third Affiliated Hospital of Third Military Medical University | ChongQing | 400042 | China | Details | ||
| Fuzhou General Hospital, PLA Nanjing Military Area Command | Fuzhou | 110016 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou | 510060 | China | Details | ||
| Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University | Hangzhou | 310016 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| The 1st Affiliated Hospital of Nanchang Unversity | Nanchang | 330006 | China | Details | ||
| The 81st Hospital of P.L.A. | Nanjing City | 210002 | China | Details | ||
| Affiliated Hospital of Nantong University | Nantong | 226001 | China | Details | ||
| Zhongshan Hospital Fudan University | Shanghai | 200032 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai | 200120 | China | Details | ||
| General Hospital of Shenyang Military Command of PLA | Shenyang | 110016 | China | Details | ||
| Hebei Medical University Fourth Hospital;(Tumor Hospital of Hebei Province) | Shijiazhuang | 050035 | China | Details | ||
| The First Affiliated Hospital of The Fourth Military Medical University (Xijing Hospital) | Xi'an | 710032 | China | Details | ||
| The Affiliated Hospital of Xuzhou Medical College | Xuzhou | 221000 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| The First Affiliated Hospital of Zhengzhou University | Zhengzhou | 450052 | China | Details | ||
| Clinical Hospital Centre Zagreb | Zagreb | 10000 | Croatia | Details | ||
| Clinical Hospital Sisters of Mercy | Zagreb | 10000 | Croatia | Details | ||
| Hospital Oncologia; Oncology | Salvador | 01101 | El Salvador | Details | ||
| Docrates Cance Center | Helsinki | 00180 | Finland | Details | ||
| Turku Uni Central Hospital; Oncology Clinics | Turku | 20520 | Finland | Details | ||
| Charité-Universitätsm. Berlin; Med. Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunolo. | Berlin | 10117 | Germany | Details | ||
| Universitätsklinikum Essen; Innere Klinik und Poliklinik für Tumorforschung | Essen | 45122 | Germany | Details | ||
| Kliniken Essen-Mitte, Evang. Huyssens-Stiftung, Klinik für Internistische Onkologie / Haematologie | Essen | 45136 | Germany | Details | ||
| Klinik Esslingen; Klinik für Allgemeine Innere Medizin, Onkologie/Haematologie | Esslingen | 73730 | Germany | Details | ||
| Universitätsklinikum Hamburg-Eppendorf; Hubertus Wald Tumorzentrum | Hamburg | 20246 | Germany | Details | ||
| Universitaetsklinikum Leipzig, Universitaeres Krebszentrum Leipzig (UCCL) | Leipzig | 04103 | Germany | Details | ||
| Klinikum Ludwigsburg; Studiensekretariat | Ludwigsburg | 71640 | Germany | Details | ||
| Universitätsmedizin der Johannes Gutenberg-Universität Mainz; II. Medizinische Klinik | Mainz | 55131 | Germany | Details | ||
| Universitätsklinikum Mannheim, Tagestherapiezentrum, Interdisziplinäres Tumorzentrum | Mannheim | 68167 | Germany | Details | ||
| Philipps-Universität Marburg; Klinik für Innere Med.; Schwerpunkt Hämatologie/Onkologie/Immunologie | Marburg | 35043 | Germany | Details | ||
| Universitätsklinikum Ulm; Zentrum für Innere Medizin Klinik für Innere Medizin I | Ulm | 89081 | Germany | Details | ||
| Medical Solution; Hematology | Guatemala | 01-010 | Guatemala | Details | ||
| Semmelweis Egyetem Onkologiai Központ | Budapest | 1083 | Hungary | Details | ||
| Orszagos Onkologiai Intezet; B Belgyogyaszati Osztaly | Budapest | 1122 | Hungary | Details | ||
| Debreceni Egyetem, Klinikai Kozpont, Onkologiai Klinika | Debrecen | 4032 | Hungary | Details | ||
| Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz;Sugarterapias Klinikai Onkologiai Intez | Miskolc | 3526 | Hungary | Details | ||
| Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika | Szeged | 6720 | Hungary | Details | ||
| Seconda Universita' Degli Studi; Divsione Di Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica | Bologna | Emilia-Romagna | 40138 | Italy | Details | |
| AUSL - IRCCS Santa Maria Nuova; U.O. Day Hospital di Oncologia | Reggio Emilia | Emilia-Romagna | 42100 | Italy | Details | |
| Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia | Udine | Friuli-Venezia Giulia | 33100 | Italy | Details | |
| Policlinico Universitario Agostino Gemelli | Roma | Lazio | 00168 | Italy | Details | |
| Asst Papa Giovanni XXIII; Oncologia Medica | Bergamo | Lombardia | 24127 | Italy | Details | |
| Irccs Ospedale San Raffaele | Milano | Lombardia | 20132 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica | Milano | Lombardia | 20141 | Italy | Details | |
| Ospedali Riuniti Di Ancona; Oncology | Ancona | Marche | 60121 | Italy | Details | |
| Ospedale Casa Sollievo Della Sofferenza IRCCS | San Giovanni Rotondo | Puglia | 71013 | Italy | Details | |
| Azlenda Ospendaliero-Universitaria Pisana; C.O. Oncologia 2 | Pisa | Toscana | 56100 | Italy | Details | |
| Ospedale Misericordia E Dolce; Oncologia Medica | Prato | Toscana | 59100 | Italy | Details | |
| Aichi Cancer Center Hospital; Clinical Oncology | Aichi | 464-8681 | Japan | Details | ||
| Nagoya university Hospital; Gastroenterological Surgery 2 | Aichi | 466-8560 | Japan | Details | ||
| National Cancer Center Hospital East; Gastroenterology | Chiba | 277-8577 | Japan | Details | ||
| National Hospital Organization Shikoku Cancer Center; Gastroenterology | Ehime | 791-0280 | Japan | Details | ||
| Kyushu University Hospital; Surgery and Science | Fukuoka | 812-8582 | Japan | Details | ||
| Gifu University Hospital; Digestive Surgery | Gifu | 501-1194 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital; Surgery | Hiroshima | 730-8518 | Japan | Details | ||
| Kobe city Medical center General Hospital; Medical Oncology | Hyogo | 650-0047 | Japan | Details | ||
| St.Marianna University School of Medicine hospital; Medical Oncology | Kanagawa | 216-8511 | Japan | Details | ||
| Kanagawa Cancer Center; Gastrointestinal Surgery | Kanagawa | 241-8515 | Japan | Details | ||
| Osaka International Cancer Institute;; Medical oncology and Gastrointestinal oncology | Osaka | 541-8567 | Japan | Details | ||
| Osaka General Medical Center; Gastroenterological Surgery | Osaka | 558-8558 | Japan | Details | ||
| Saitama Cancer Center; Gastroenterology | Saitama | 362-0806 | Japan | Details | ||
| National Cancer Center Hospital; Gastrointestinal Oncology | Tokyo | 104-0045 | Japan | Details | ||
| Toyama University Hospital;Gastroenterology and Hematology | Toyama | 930-0194 | Japan | Details | ||
| Kazakh Scientific Research Institution Of Oncology and Radiology; Chemotherapy department | Almaty | 050022 | Kazakhstan | Details | ||
| Kyungpook National University Medical Center | Daegu | 41404 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | (0)6351 | Korea, Republic of | Details | ||
| Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology | Seoul | 03080 | Korea, Republic of | Details | ||
| Yonsei Medical Center; Dept. of Medicine , Division of Hemato-Oncology | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center; Medical Oncology | Seoul | 05505 | Korea, Republic of | Details | ||
| Seoul St Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Hospital Universiti Sains Malaysia [Neurology] | Kubang Kerian | Kelantan | 16150 | Malaysia | Details | |
| Hospital Kuala Lumpur; Jabatan Radioterapi dan Onkologi | Kuala Lumpur | 50586 | Malaysia | Details | ||
| University Malaya Medical Centre; Clinical Oncology Unit, | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Hospital Wanita dan Kanak-Kanak Sabah | Sabah | 88996 | Malaysia | Details | ||
| Hospital Angeles Metropolitano; Room 220 | Mexico City | Mexico CITY (federal District) | 06760 | Mexico | Details | |
| Inst. Nacional de Cancerologia; Investigacion Clinica | Mexico City | 14000 | Mexico | Details | ||
| Oaxaca Site Management Organization | Oaxaca | 68000 | Mexico | Details | ||
| Academisch Medisch Centrum Universiteit Amsterdam | Amsterdam | 1105 AZ | Netherlands | Details | ||
| Clinical Hospital; Oncology Department | Bitola | 7000 | North Macedonia | Details | ||
| University Clinic for Radiotherapy and Oncology | Skopje | 1000 | North Macedonia | Details | ||
| Medical Research Centre | Panama | Panama | Details | |||
| Centro Medico Monte Carmelo | Arequipa | 04001 | Peru | Details | ||
| Hospital Sabogal; Oncology | Callao | 02 | Peru | Details | ||
| Hosp Nacion Edgardo Rebagliati; Oncologia Medica | Jesus Maria | Lima 11 | Peru | Details | ||
| Clinica Internacional, Sede San Borja; Unidad de Investigacion de Clínica Internacional | Lima | Lima 41 | Peru | Details | ||
| Clinica San Borja | Lima | Lima 41 | Peru | Details | ||
| Bialostockie Ctr Onkologii; Oddzial Chemioterapii Dziennej | Bialystok | 15-027 | Poland | Details | ||
| Szpital Specjalistyczny Podkarpacki Ośrodek Onkologiczny | Brzozów | 36-200 | Poland | Details | ||
| Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii | Bydgoszcz | 85-796 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Kliniki Onkologii | Kraków | 30-688 | Poland | Details | ||
| SPZOZ Opolskie Centrum Onkologii im. Prof. Tadeusza Koszarawskiego | Opole | 45-060 | Poland | Details | ||
| NZOZ Centrum Medyczne HCP Sp. z o.o. | Poznan | 61-485 | Poland | Details | ||
| Wojewódzki Szpital Specjalistyczny Nr 3 | Rybnik | 44-200 | Poland | Details | ||
| Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie; Klinika Gastroenterologii Onkologicznej | Warszawa | 02-781 | Poland | Details | ||
| Cardiomed Medical Center | Cluj-Napoca | 400015 | Romania | Details | ||
| Oncology Center Sf. Nectarie | Craiova | 200347 | Romania | Details | ||
| Euroclinic Center of Oncology SRL | Iasi | 700106 | Romania | Details | ||
| Clinical Oncology Dispensary of Ministry of Health of Tatarstan | Kazan | 420029 | Russian Federation | Details | ||
| Clinical Oncology Dispensary; Chemotherapy | Omsk | 644013 | Russian Federation | Details | ||
| SBI for HPE "Ryazan State Medical University n.a. I.P. Pavlov" of MoH of RF | Ryazan | 390011 | Russian Federation | Details | ||
| SBI of Healthcare Samara Regional Clinical Oncology Dispensary | Samara | 443031 | Russian Federation | Details | ||
| Hospital General Universitario de Elche; Servicio de Oncologia | Elche | Alicante | 03203 | Spain | Details | |
| Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Hospital del Mar; Servicio de Oncologia | Barcelona | 08003 | Spain | Details | ||
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau; Servicio de Oncologia | Barcelona | 08041 | Spain | Details | ||
| Hospital Duran i Reynals; Oncologia | Barcelona | 08907 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| CHUV; Departement d'Oncologie | Lausanne | 1011 | Switzerland | Details | ||
| Luzerner Kantonsspital; Medizinische Onkologie | Luzern | 6004 | Switzerland | Details | ||
| Taichung Veterans General Hospital; Dept of Surgery | Taichung | 407 | Taiwan | Details | ||
| National Cheng Kung University Hospital; Oncology | Tainan | 00704 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei City | 112 | Taiwan | Details | ||
| National Taiwan Uni Hospital; Dept of Oncology | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Medical Foundation - Linkou; Division of Hematology- Oncology | Taoyuan | 333 | Taiwan | Details | ||
| Rajavithi Hospital; Division of Medical Oncology | Bangkok | 10400 | Thailand | Details | ||
| Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc | Bangkok | 10400 | Thailand | Details | ||
| Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology | Bangkok | 10700 | Thailand | Details | ||
| Khonkaen Hospital | Khonkaen | 40000 | Thailand | Details | ||
| Songklanagarind Hospital; Department of Oncology | Songkhla | 90110 | Thailand | Details | ||
| Ankara Uni School of Medicine; Medical Oncology | Ankara | 06590 | Turkey | Details | ||
| Akdeniz University Medical Faculty; Medical Oncology Department | Antalya | 07070 | Turkey | Details | ||
| Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department | Edirne | 22770 | Turkey | Details | ||
| Ataturk University Medical Faculty Yakutiye Research Hospital Medical Oncology Department | Erzurum | 25240 | Turkey | Details | ||
| Istanbul Uni Cerrahpasa Medical Faculty Hospital; Medical Oncology | Istanbul | 34300 | Turkey | Details | ||
| TC Necmettin Erbakan University Meram Medical Faculty Hospital | Konya | 42080 | Turkey | Details | ||
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | Malatya | 44280 | Turkey | Details |