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| NCT ID | NCT01828112 |
| Title | LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | TUR | NLD | LBN | ITA | ISR | IRL | GBR | FRA | ESP | DEU | CHE | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Cancer Specialists of North Florida | Jacksonville | Florida | 32256 | United States | Details | |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | United States | Details | |
| Loyola University Medical Center | Marywood | Illinois | 60153 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | United States | Details | |
| Novartis Investigative Site | Bruxelles | 1000 | Belgium | Details | ||
| Novartis Investigative Site | Bruxelles | 1200 | Belgium | Details | ||
| Novartis Investigative Site | Edegem | 2650 | Belgium | Details | ||
| Novartis Investigative Site | Leuven | 3000 | Belgium | Details | ||
| Novartis Investigative Site | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Novartis Investigative Site | Marseille cedex 20 | Bouches Du Rhone | 13915 | France | Details | |
| Novartis Investigative Site | Besancon cedex | 25030 | France | Details | ||
| Novartis Investigative Site | Brest | 29609 | France | Details | ||
| Novartis Investigative Site | Caen | 14021 | France | Details | ||
| Novartis Investigative Site | Le Mans | 72000 | France | Details | ||
| Novartis Investigative Site | Mulhouse cedex | 68070 | France | Details | ||
| Novartis Investigative Site | Paris | 75970 | France | Details | ||
| Novartis Investigative Site | Strasbourg | F 67085 | France | Details | ||
| Novartis Investigative Site | Suresnes | 92150 | France | Details | ||
| Novartis Investigative Site | Bad Berka | 99438 | Germany | Details | ||
| Novartis Investigative Site | Essen | 45147 | Germany | Details | ||
| Novartis Investigative Site | Esslingen | 73730 | Germany | Details | ||
| Novartis Investigative Site | Frankfurt | 60590 | Germany | Details | ||
| Novartis Investigative Site | Heidelberg | 69120 | Germany | Details | ||
| Novartis Investigative Site | Koeln | 51109 | Germany | Details | ||
| Novartis Investigative Site | Tuebingen | 72076 | Germany | Details | ||
| Novartis Investigative Site | Ulm | 89081 | Germany | Details | ||
| Novartis Investigative Site | Hong Kong | Hong Kong | Details | |||
| Novartis Investigative Site | Pokfulam | Hong Kong | Details | |||
| Novartis Investigative Site | Limerick | Co Limerick | V94 YX29 | Ireland | Details | |
| Novartis Investigative Site | Dublin 4 | DO4 | Ireland | Details | ||
| Novartis Investigative Site | Kfar Saba | 44281 | Israel | Details | ||
| Novartis Investigative Site | Ramat Gan | 52621 | Israel | Details | ||
| Novartis Investigative Site | Avellino | AV | 83100 | Italy | Details | |
| Novartis Investigative Site | Monza | MB | 20900 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20132 | Italy | Details | |
| Novartis Investigative Site | Perugia | PG | 06129 | Italy | Details | |
| Novartis Investigative Site | Pisa | PI | 56124 | Italy | Details | |
| Novartis Investigative Site | Aviano | PN | 33081 | Italy | Details | |
| Novartis Investigative Site | Reggio Emilia | RE | 42123 | Italy | Details | |
| Novartis Investigative Site | Roma | RM | 00189 | Italy | Details | |
| Novartis Investigative Site | Orbassano | TO | 10043 | Italy | Details | |
| Novartis Investigative Site | Verona | VR | 37126 | Italy | Details | |
| Novartis Investigative Site | Nagoya | Aichi | 464 8681 | Japan | Details | |
| Novartis Investigative Site | Kashiwa | Chiba | 277 8577 | Japan | Details | |
| Novartis Investigative Site | Fukuoka city | Fukuoka | 812-8582 | Japan | Details | |
| Novartis Investigative Site | Fukuoka-city | Fukuoka | 811-1395 | Japan | Details | |
| Novartis Investigative Site | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Novartis Investigative Site | Okayama-city | Okayama | 700-8558 | Japan | Details | |
| Novartis Investigative Site | Hirakata-city | Osaka | 573-1191 | Japan | Details | |
| Novartis Investigative Site | Osaka Sayama | Osaka | 589 8511 | Japan | Details | |
| Novartis Investigative Site | Osaka-city | Osaka | 541-8567 | Japan | Details | |
| Novartis Investigative Site | Takatsuki | Osaka | 569-8686 | Japan | Details | |
| Novartis Investigative Site | Koto ku | Tokyo | 135 8550 | Japan | Details | |
| Novartis Investigative Site | Niigata | 951 8520 | Japan | Details | ||
| Novartis Investigative Site | Seoul | Seocho Gu | 06591 | Korea, Republic of | Details | |
| Novartis Investigative Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 03722 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 05505 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Ashrafieh | 166830 | Lebanon | Details | ||
| Novartis Investigative Site | Groningen | 9713 GZ | Netherlands | Details | ||
| Novartis Investigative Site | Lisboa | 1649 035 | Portugal | Details | ||
| Novartis Investigative Site | Moscow Region Istra Village | 143423 | Russian Federation | Details | ||
| Novartis Investigative Site | Moscow | 115478 | Russian Federation | Details | ||
| Novartis Investigative Site | Saint Petersburg | 197022 | Russian Federation | Details | ||
| Novartis Investigative Site | Singapore | 119074 | Singapore | Details | ||
| Novartis Investigative Site | Singapore | 168583 | Singapore | Details | ||
| Novartis Investigative Site | Sevilla | Andalucia | 41009 | Spain | Details | |
| Novartis Investigative Site | Sevilla | Andalucia | 41013 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Cataluna | 08028 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Catalunya | 08035 | Spain | Details | |
| Novartis Investigative Site | Valencia | Comunidad Valenciana | 46010 | Spain | Details | |
| Novartis Investigative Site | La Coruna | Galicia | 15006 | Spain | Details | |
| Novartis Investigative Site | Santiago De Compostela | Galicia | 15706 | Spain | Details | |
| Novartis Investigative Site | Madrid | 28034 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28041 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28046 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28222 | Spain | Details | ||
| Novartis Investigative Site | Luzern | 6000 | Switzerland | Details | ||
| Novartis Investigative Site | St Gallen | 9007 | Switzerland | Details | ||
| Novartis Investigative Site | Istanbul | TUR | 34098 | Turkey | Details | |
| Novartis Investigative Site | Ankara | 06230 | Turkey | Details | ||
| Novartis Investigative Site | Pendik Istanbul | 34899 | Turkey | Details | ||
| Novartis Investigative Site | Cheltenham | Gloucestershire | GL53 7AN | United Kingdom | Details | |
| Novartis Investigative Site | Aberdeen | Grampian Region | AB25 2ZN | United Kingdom | Details | |
| Novartis Investigative Site | Leicester | LE1 5WW | United Kingdom | Details | ||
| Novartis Investigative Site | London | SE1 9RT | United Kingdom | Details | ||
| Novartis Investigative Site | Southampton | SO30 3JB | United Kingdom | Details | ||
| Oklahoma Cancer Specialists and Research Institute | Tulsa | Oklahoma | 74136 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| Texas Oncology Cancer Care and Research Center | Waco | Texas | 76712 | United States | Details | |
| Texas Oncology-Sugarland | Sugar Land | Texas | 77479 | United States | Details | |
| Uni Of Iowa Hospitals And Clinics | Iowa | Iowa | 52242 | United States | Details | |
| University Of Miami | Miami | Florida | 33136 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details |
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