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| NCT ID | NCT01939223 |
| Title | COlorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo?Controlled Phase-III STudy (COAST) |
| Acronym | COAST |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Bayer |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | ITA | ISR | GBR | FRA | ESP | DEU | CAN | BRA | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Laguna Hills | California | 92653 | United States | Details | ||
| Los Angeles | California | 90033 | United States | Details | ||
| Los Angeles | California | 90089 | United States | Details | ||
| Los Angeles | California | 90095 | United States | Details | ||
| New Haven | Connecticut | 06520-8064 | United States | Details | ||
| New Orleans | Louisiana | 70121 | United States | Details | ||
| Baltimore | Maryland | 21201-1595 | United States | Details | ||
| Detroit | Michigan | 48202 | United States | Details | ||
| Rochester | Minnesota | 55905 | United States | Details | ||
| Omaha | Nebraska | 68106 | United States | Details | ||
| New Brunswick | New Jersey | 08903-2681 | United States | Details | ||
| Buffalo | New York | 14263-0001 | United States | Details | ||
| New York | New York | 10021 | United States | Details | ||
| Syracuse | New York | 13210 | United States | Details | ||
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Philadelphia | Pennsylvania | 19104 | United States | Details | ||
| Chattanooga | Tennessee | 37421 | United States | Details | ||
| Germantown | Tennessee | 38138 | United States | Details | ||
| Dallas | Texas | 75390 | United States | Details | ||
| Richmond | Virginia | 23298-0037 | United States | Details | ||
| Kirkland | Washington | 98034 | United States | Details | ||
| Seattle | Washington | 98101 | United States | Details | ||
| Seattle | Washington | 98109 | United States | Details | ||
| Liverpool | New South Wales | 2170 | Australia | Details | ||
| East Melbourne | Victoria | 3002 | Australia | Details | ||
| Bentleigh East | 3165 | Australia | Details | |||
| Malvern | 3144 | Australia | Details | |||
| Edegem | 2650 | Belgium | Details | |||
| Leuven | 3000 | Belgium | Details | |||
| Liege | 4000 | Belgium | Details | |||
| Belo Horizonte | Minas Gerais | 30110-090 | Brazil | Details | ||
| Porto Alegre | Rio Grande do Sul | Brazil | Details | |||
| São José do Rio Preto | Sao Paulo | Brazil | Details | |||
| São Paulo | Sao Paulo | 01246-000 | Brazil | Details | ||
| Edmonton | Alberta | T6G 1Z2 | Canada | Details | ||
| Toronto | Ontario | M5G 1X8 | Canada | Details | ||
| Sherbrooke | Quebec | J1H 5N4 | Canada | Details | ||
| Montreal | H2W 1S6 | Canada | Details | |||
| Fujian Medical University Union Hospital | Fuzhou | Fujian | 350001 | China | Details | |
| Guangzhou | Guangdong | 510060 | China | Details | ||
| Guangzhou | Guangdong | 510655 | China | Details | ||
| Harbin | Heilongjiang | China | Details | |||
| Wuhan | Hubei | 430033 | China | Details | ||
| Changsha | Hunan | 410008 | China | Details | ||
| Xi'an | Shaanxi | 710032 | China | Details | ||
| Xi'an | Shaanxi | 710038 | China | Details | ||
| Kunming | Yunnan | 650118 | China | Details | ||
| Hangzhou | Zhejiang | 310009 | China | Details | ||
| Hangzhou | Zhejiang | 310016 | China | Details | ||
| Beijing | 100021 | China | Details | |||
| Beijing | 100071 | China | Details | |||
| Beijing | 100142 | China | Details | |||
| Beijing | 100730 | China | Details | |||
| Shanghai | 200030 | China | Details | |||
| Shanghai | 200032 | China | Details | |||
| Shanghai | 200127 | China | Details | |||
| Bordeaux | 33076 | France | Details | |||
| Brest | 29285 | France | Details | |||
| Clermont-Ferrand | 63000 | France | Details | |||
| LYON Cedex 08 | 69373 | France | Details | |||
| Marseille | 13385 | France | Details | |||
| Paris | 75651 | France | Details | |||
| Poitiers Cedex | 86021 | France | Details | |||
| Tours | 37044 | France | Details | |||
| Villejuif | 94800 | France | Details | |||
| München | Bayern | 81377 | Germany | Details | ||
| Frankfurt | Hessen | 60590 | Germany | Details | ||
| Oldenburg | Niedersachsen | 26133 | Germany | Details | ||
| Mainz | Rheinland-Pfalz | 55131 | Germany | Details | ||
| Berlin | 12200 | Germany | Details | |||
| Haifa | 3109601 | Israel | Details | |||
| Ramat Gan | 52482 | Israel | Details | |||
| Tel Aviv | 64239 | Israel | Details | |||
| Napoli | Campania | 80131 | Italy | Details | ||
| Reggio Emilia | Emilia-Romagna | 42123 | Italy | Details | ||
| Udine | Friuli-Venezia Giulia | 33100 | Italy | Details | ||
| Roma | Lazio | 00189 | Italy | Details | ||
| Brescia | Lombardia | 25124 | Italy | Details | ||
| Milano | Lombardia | 20089 | Italy | Details | ||
| Milano | Lombardia | 20133 | Italy | Details | ||
| Milano | Lombardia | 20141 | Italy | Details | ||
| Foggia | Puglia | 71013 | Italy | Details | ||
| Firenze | Toscana | 50134 | Italy | Details | ||
| Pisa | Toscana | 56126 | Italy | Details | ||
| Kashiwa | Chiba | 277-8577 | Japan | Details | ||
| Sapporo | Hokkaido | 006-8555 | Japan | Details | ||
| Sapporo | Hokkaido | 060-0004 | Japan | Details | ||
| Sapporo | Hokkaido | 060-8648 | Japan | Details | ||
| Akashi | Hyogo | 673-8558 | Japan | Details | ||
| Amagasaki | Hyogo | 660-8511 | Japan | Details | ||
| Kobe | Hyogo | 650-0047 | Japan | Details | ||
| Kasama | Ibaraki | 309-1793 | Japan | Details | ||
| Yokohama | Kanagawa | 241-8515 | Japan | Details | ||
| Suita | Osaka | 565-0871 | Japan | Details | ||
| Takatsuki | Osaka | 569-8686 | Japan | Details | ||
| Sunto | Shizuoka | 411-8777 | Japan | Details | ||
| Shimotsuke | Tochigi | 329-0498 | Japan | Details | ||
| Koto-ku | Tokyo | 135-8550 | Japan | Details | ||
| Minato-ku | Tokyo | 105-8471 | Japan | Details | ||
| Mitaka | Tokyo | 181-8611 | Japan | Details | ||
| Shinagawa | Tokyo | 142-8666 | Japan | Details | ||
| Shinjuku-ku | Tokyo | 160-8582 | Japan | Details | ||
| Fukuoka | 810-8563 | Japan | Details | |||
| Fukuoka | 811-1395 | Japan | Details | |||
| Fukuoka | 812-8582 | Japan | Details | |||
| Almada | 2801-951 | Portugal | Details | |||
| Porto | 4200-072 | Portugal | Details | |||
| Santa Maria da Feira | 4520-531 | Portugal | Details | |||
| Alicante | 03010 | Spain | Details | |||
| Badajoz | 06080 | Spain | Details | |||
| Barcelona | 08036 | Spain | Details | |||
| Córdoba | 14004 | Spain | Details | |||
| Madrid | 28007 | Spain | Details | |||
| Madrid | 28034 | Spain | Details | |||
| Madrid | 28040 | Spain | Details | |||
| Valencia | 46009 | Spain | Details | |||
| Valencia | 46013 | Spain | Details | |||
| Royal Marsden NHS Trust (Surrey) | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Bristol | BS2 8ED | United Kingdom | Details | |||
| London | SW3 6JJ | United Kingdom | Details | |||
| London | WC1E 6BT | United Kingdom | Details |