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| NCT ID | NCT01989676 |
| Title | A Study Of PF-05280014 [Trastuzumab-Pfizer] Or Herceptin® [Trastuzumab-EU] Plus Paclitaxel In HER2 Positive First Line Metastatic Breast Cancer Treatment (REFLECTIONS B327-02) |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Pfizer |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SVK | ROU | POL | LVA | HUN | GRC | CZE | BRA | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Cancer Center of Central Connecticut | Plainville | Connecticut | 06062 | United States | Details | |
| Cancer Center of Central Connecticut | Southington | Connecticut | 06489 | United States | Details | |
| Florida Cancer Research Institute | Boca Raton | Florida | 33428 | United States | Details | |
| Florida Cancer Research Institute | Plantation | Florida | 33324 | United States | Details | |
| COIBA - Centro de Oncologia e Investigacion Buenos Aires | Berazategui | Buenos Aires | B1884BBF | Argentina | Details | |
| Instituto De Oncologia De Rosario | Rosario | Santa FE | S2000KZE | Argentina | Details | |
| Centro Medico San Roque | San Miguel de Tucuman | Tucuman | T4000IAK | Argentina | Details | |
| Sanatorio de la Providencia | C.a.b.a | C1050AAK | Argentina | Details | ||
| CRIO - Centro Regional Integrado de Oncologia | Fortaleza | CE | 60336-045 | Brazil | Details | |
| Associacao de Combate ao Cancer em Goias - Hospital Araujo Jorge | Goiania | GO | 74605070 | Brazil | Details | |
| Liga Paranaense de Combate ao Cancer - Hospital Erasto Gaertner | Curitiba | Parana | 81520-060 | Brazil | Details | |
| Instituto do Cancer de Londrina - Hospital do Cancer de Londrina - HCL | Londrina | Parana | 86015-520 | Brazil | Details | |
| Hospital Bruno Born (Sociedade Beneficencia e Caridade de Lajeado) | Lajeado | RIO Grande DO SUL | 95900-000 | Brazil | Details | |
| Associacao Hospital de Caridade Ijui | Ijui | RS | 98700-000 | Brazil | Details | |
| Centro de Pesquisa em Oncologia - Uniao Brasileira de Educacao e Assistencia | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral | Itajai | Santa Catarina | 88301-215 | Brazil | Details | |
| Fundacao Pio XII - Hospital de Cancer de Barretos | Barretos | SAO Paulo | 14784-400 | Brazil | Details | |
| Centro de Pesquisas Oncologicas de Santa Catarina - CEPON | Florianopolis | SC | 88034-000 | Brazil | Details | |
| Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral | Itajai | SC | 88301-220 | Brazil | Details | |
| CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Faculdade de Medicina do ABC | Santo Andre | SP | 09060-650 | Brazil | Details | |
| CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Faculdade de Medicina do ABC | Santo Andre | SP | 09060-870 | Brazil | Details | |
| Clinica Alemana de Temuco | Temuco | Region DE LA Araucania | 4810297 | Chile | Details | |
| Centro de Investigacion Clinica SIM | Temuco | Region DE LA Araucania | 4810469 | Chile | Details | |
| Administrative office | Temuco | Region DE LA Araucania | 4810561 | Chile | Details | |
| Fresenius Kabi Chile Therapia iv | Santiago | RM | 7780050 | Chile | Details | |
| Hospital Clinico Vina Del Mar | Vina del Mar | V Region | 2520612 | Chile | Details | |
| Instituto Oncologico, Clinica Renaca | Vina del Mar | V Region | 2540364 | Chile | Details | |
| Hospital Naval Almirante Nef | V Region | Chile | Details | |||
| Instituto Oncologico Clinica Renaca | V Region | Chile | Details | |||
| Onkologicka klinika VFN a 1. LF UK, Fakultni poliklinika | Praha 2 | 128 08 | Czechia | Details | ||
| General Hospital of Chania "O Agios Georgios" | Chania | Crete | 73300 | Greece | Details | |
| Interbalkan European Medical Center | Pylaia | Thessaloniki | 57001 | Greece | Details | |
| General Hospital of Athens "Hippokration" | Athens | 11527 | Greece | Details | ||
| Bacs-Kiskun Megyei Korhaz, Onkoradiologiai Kozpont | Kecskemet | 6000 | Hungary | Details | ||
| Borsod-Abauj-Zemplen Megyei Korhaz, es Egyetemi Oktatokorhaz, Klinikai Onkologiai es Sugarterapias | Miskolc | 3526 | Hungary | Details | ||
| Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz - Rendelointezet, Megyei Onkologiai Kozpont | Szolnok | 5000 | Hungary | Details | ||
| Markusovszky Egyetemi Oktatokorhaz | Szombathely | 9700 | Hungary | Details | ||
| Department of Medicine New Block | Visakhapatnam | Andhra Pradesh | 530002 | India | Details | |
| Manipal Hospital | Bengaluru | Karnataka | 560017 | India | Details | |
| Manipal Centre for Clinical Research | Manipal | Karnataka | 576104 | India | Details | |
| Tata Memorial Centre, Tata Memorial Hospital | Mumbai | Maharashtra | 400012 | India | Details | |
| Shatabdi Super Speciality Hospital | Nashik | Maharashtra | 422 005 | India | Details | |
| Advanced Centre for Treatment Research and Education in Cancer (ACTREC) | Navi Mumbai | Maharashtra | 401210 | India | Details | |
| Deenanath Mangeshkar Hospital & Research Centre | Pune | Maharashtra | 411 004 | India | Details | |
| Sahyadri Clinical Research & Development Centre | Pune | Maharashtra | 411004 | India | Details | |
| Sahyadri Speciality Hospital | Pune | Maharashtra | 411004 | India | Details | |
| Acharya Harihar Regional Cancer Center | Cuttack | Odisha | 753007 | India | Details | |
| Acharya Tulsi Regional Cancer Treatment and Research Institute | Bikaner | Rajasthan | 334003 | India | Details | |
| Meenakshi Mission Hospital and Research Centre | Madurai | Tamil NADU | 625107 | India | Details | |
| MNJ Institute of Oncology & Regional Cancer Center | Hyderabad | Telangana | 500004 | India | Details | |
| National Hospital Organization Nagoya Medical Center | Nagoya | Aichi | 460-0001 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center | Fukuoka-Shi | Fukuoka | 811-1395 | Japan | Details | |
| Japan Community Health care Organization Kurume General Hospital | Kurume-city | Fukuoka | 830-0013 | Japan | Details | |
| Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Kumamoto University Hospital | Kumamoto-city | Kumamoto | 8608556 | Japan | Details | |
| Saitama Cancer Center Hospital | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital | Bunkyo-ku | Tokyo | 113-8677 | Japan | Details | |
| National Hospital Organization Tokyo Medical Center | Meguro-Ku | Tokyo | 152-8902 | Japan | Details | |
| Showa University Hospital | Shinagawa-ku | Tokyo | 142-8666 | Japan | Details | |
| Chiba Cancer Center | Chiba | 260-8717 | Japan | Details | ||
| Hakuaikai Medical Corporation Sagara Hospital | Kagoshima | 892-0833 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Nakanoshima Osaka Breast Clinic | Osaka | 553-0003 | Japan | Details | ||
| Osaka Breast Clinic | Osaka | 553-0003 | Japan | Details | ||
| Shizuoka General Hospital | Shizuoka | 420-8527 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju-si | Chungcheongbuk-do | 28644 | Korea, Republic of | Details | |
| Ulsan University Hospital | Ulsan | Korea | 44033 | Korea, Republic of | Details | |
| Pusan National University Hospital | Busan | 49241 | Korea, Republic of | Details | ||
| Kyungpook National University Chilgok Hospital | Daegu | 41404 | Korea, Republic of | Details | ||
| National Cancer Centre | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| P.Stradins Clinical University Hospital | Riga | LV 1002 | Latvia | Details | ||
| Instituto Nacional de Cancerologia | Mexico City | Distrito Federal | 14080 | Mexico | Details | |
| Consultorio dentro de la Torre Medica Dalinde (Oncologia Medica) | Mexico | Distrito Federal | 06760 | Mexico | Details | |
| Inter Hosp S.A. de C.V. "Centro Medico Dalinde" | Mexico | Distrito Federal | 06760 | Mexico | Details | |
| Oaxaca Site Management Organization S.C. | Oaxaca | 68000 | Mexico | Details | ||
| Cancerologia de Queretaro S.C. | Queretaro | 76090 | Mexico | Details | ||
| Hospital Militar Central | Lima | 11 | Peru | Details | ||
| INNPARES | Lima | 11 | Peru | Details | ||
| Resocentro | Lima | 18 | Peru | Details | ||
| Clinica Anglo Americana | Lima | 27 | Peru | Details | ||
| Instituto de Oncologia y Radioterapia de la Clinica Ricardo Palma | Lima | 27 | Peru | Details | ||
| Radiologos S.R.L. | Lima | 27 | Peru | Details | ||
| Instituto Nacional de Enfermedades Neoplasicas | Lima | 34 | Peru | Details | ||
| Siglo XXI | Lima | 41 | Peru | Details | ||
| Resocentro | Lima | Lima 18 | Peru | Details | ||
| Siglo XXI | Lima | Lima 41 | Peru | Details | ||
| Cebu Doctors' University Hospital | Cebu City | Cebu | 6000 | Philippines | Details | |
| Cardinal Santos Medical Center | San Juan City | Mentro Manila | 1502 | Philippines | Details | |
| Manila Doctors Hospital | Manila | Metro Manila | 1000 | Philippines | Details | |
| Veterans Memorial Medical Center | Quezon City | Metro Manila | 1110 | Philippines | Details | |
| University of Philippines Manila-Philippine General Hospital | Manila | NCR | 1000 | Philippines | Details | |
| The Medical City | Pasig City | NCR | 1605 | Philippines | Details | |
| St. Luke's Medical Center | Quezon City | NCR | 1102 | Philippines | Details | |
| The Research Institute at Perpetual Succor Hospital | Cebu City | Region VII | 6000 | Philippines | Details | |
| Manila Doctors Hospital | Manila | 1000 | Philippines | Details | ||
| COPERNICUS Podmiot Leczniczy Sp. z o.o. Wojewodzkie Centrum Onkologii | Gdansk | 80-219 | Poland | Details | ||
| Szpitale Pomorskie Sp. z o.o. Oddzial Onkologii i Radioterapii | Gdynia | 81-519 | Poland | Details | ||
| Centrum Terapii Wspolczesnej | Lodz | 90-242 | Poland | Details | ||
| SPZOZ MSW z Warminsko-Mazurskim Centrum Onkologii w Olsztynie, Oddzial Kliniczny Chemioterapii | Olsztyn | 10-228 | Poland | Details | ||
| MRUKMED. Lekarz Beata Madej Mruk i Partner. Sp. p. Oddzial nr 1 w Rzeszowie | Rzeszow | 35-085 | Poland | Details | ||
| Magodent Sp. z o.o. Oddzial Onkologii Klinicznej/Chemioterapii | Warszawa | 03-291 | Poland | Details | ||
| Hospital de Braga | Braga | 4710 243 | Portugal | Details | ||
| Hospital CUF Descobertas | Lisboa | 1998-018 | Portugal | Details | ||
| Institutul Oncologic Prof. Dr. Ion Chiricuta | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| S.C. Medisprof S.R.L | Cluj-Napoca | Cluj | 400641 | Romania | Details | |
| Centrul de Oncologie Sf. Nectarie | Craiova | Dolj | 200347 | Romania | Details | |
| SC Oncolab SRL, Oncologie | Craiova | Jud Dolj | 200385 | Romania | Details | |
| Spitalul Universitar de Urgenta, Departamentul Oncologie Medicala | Bucuresti | 050098 | Romania | Details | ||
| Spitalul Clinic Judetean de Urgenta Sibiu | Sibiu | 550245 | Romania | Details | ||
| Spitalul Judetean de Urgenta "Sf.Ioan cel Nou", Sectia Oncologie | Suceava | 720237 | Romania | Details | ||
| Spitalul Clinic Municipal de Urgenta Timisoara, Sectia Clinica Oncologie Medicala | Timisoara | 300595 | Romania | Details | ||
| Republic Clinical Hospital of Emergency Care | Grozny | Chechenkaya Republic | 364020 | Russian Federation | Details | |
| State Healthcare Institution Kursk Regional Oncological Dispensary of the Healthcare Committee | Kislino Settlement | Kursk | 305524 | Russian Federation | Details | |
| State Budgetary Healthcare Institution "Leningrad Regional Oncological Dispensary" | Kuzmolovo, Vsevolozhskiy | Leningrad Region | 188663 | Russian Federation | Details | |
| FSBSI Russian Cancer Research Center n.a. N.N.Blokhin | Moscow | NAP | 115478 | Russian Federation | Details | |
| GBUZ of Perm region "Perm regional oncology dispensary" | Perm | NAP | 614066 | Russian Federation | Details | |
| Federal State Budgetary Institution ¿National Medical Research Oncology Centre named after N.N. | Saint-Petersburg | Pos.pesochny | 197758 | Russian Federation | Details | |
| State Healthcare Institution, Republican Clinical Oncology Dispensary of the Ministry of | Ufa | Republic OF Bashkortostan | 450054 | Russian Federation | Details | |
| GBUZ Republican Clinical Hospital n.a. G.F. Kuvatova | Ufa | Republic OF Baskortostan | 450005 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of the Ministry of Healthcare of Baskortostan Republic | Ufa | Republic OF Baskortostan | 450054 | Russian Federation | Details | |
| State Budgetary Healthcare Institution ''Republic Oncological Dispensary'' | Petrozavodsk | Republic OF Karelia | 185002 | Russian Federation | Details | |
| State budget institution of healthcare of Mordovia Republic "Republic Oncology Dispensary" | Saransk | Republic OF Mordovia | 430032 | Russian Federation | Details | |
| Rostov Research Institute of Oncology | Rostov-on-Don | Rostov Region | 344037 | Russian Federation | Details | |
| Private medical institution Euromedservice | Pushkin | Saint Petersburg | 196603 | Russian Federation | Details | |
| Saint-Petersburg Clinical Research Center of Specialized Types of Medical Care (Oncology) | Poselok Pesochny | Saint-petersburg | 197758 | Russian Federation | Details | |
| LLC Medekspert | Kislovodsk | Stavropol Region | 357700 | Russian Federation | Details | |
| Federal State Budgetary Healthcare Institution of "Clinical Hospital #101 of Federal Medical and | Lermontov | Stavropol Region | 357340 | Russian Federation | Details | |
| Centre of Specialized kinds of Medical Care of Pyatigorsk city | Pyatigorsk | Stavropol Region | 357502 | Russian Federation | Details | |
| State Budgetary Healthcare Institution of Stavropol Region Pyatigorsk Oncology Dispensary | Pyatigorsk | Stavropol Region | 357502 | Russian Federation | Details | |
| LLC Novaya Clinica | Pyatigorsk | Stavropol Region | 357519 | Russian Federation | Details | |
| Pyatigorsk City Hospital #2 | Pyatigorsk | Stavropol Region | 357538 | Russian Federation | Details | |
| Stavropol Regional Hospital for War Veterans | Pyatigorsk | Stavropol Region | 357563 | Russian Federation | Details | |
| State Budgetary Healthcare Institution Volgograd Regional Clinical Oncology Dispensary | Volzhskiy | Volgograd Region | 404130 | Russian Federation | Details | |
| GBUZ Arkhangelsk Regional Clinical Oncological dispensary | Arkhangelsk | 163045 | Russian Federation | Details | ||
| State Budgetary Healthcare Institution "Chelyabinsk Regional Clinical Oncological Dispensary" | Chelyabinsk | 454087 | Russian Federation | Details | ||
| "Regional Budgetary Healthcare Institution ""Ivanovo Regional Oncology Dispensary""" | Ivanovo | 153040 | Russian Federation | Details | ||
| SBIH of Kaluga Region "Kaluga Regional Clinical Oncology Dispensary" | Kaluga | 248007 | Russian Federation | Details | ||
| GBUZ "Regional Oncology Dispensary #2" | Magnitogorsk | 455001 | Russian Federation | Details | ||
| Federal State Budgetary Institution "Russian Oncological Scientific Center n.a. N.N. Blokhin" of | Moscow | 115478 | Russian Federation | Details | ||
| LLC VitaMed | Moscow | 121309 | Russian Federation | Details | ||
| LLC VitaMed | Moscow | 129515 | Russian Federation | Details | ||
| State Budgetary Healthcare Institution "Nizhniy Novgorod Regional Oncological Dispensary" | Nizhniy Novgorod | 603081 | Russian Federation | Details | ||
| "BIH of Omsk Region ""Clinical oncological dispensary""" | Omsk | 644046 | Russian Federation | Details | ||
| Budgetary Institution of Healthcare of Orel region "Orel oncological dispensary" | Orel | 302020 | Russian Federation | Details | ||
| SBEI HPE RyazSMU of MoH of the Russian Federation based on SBI of Ryazan Region "Regional CLinical | Ryazan | 390011 | Russian Federation | Details | ||
| SBEI of HPE "First Saint Petersburg State Medical University | Saint Petersburg | 197022 | Russian Federation | Details | ||
| SBI "North-Western State Medical University n.a. I. I. Mechnikov" of the MoH of the Russian | Saint-Petersburg | 195067 | Russian Federation | Details | ||
| Non-state healthcare agency Road Clinical Hospital PLC Russian Railways | Saint-Petersburg | 195271 | Russian Federation | Details | ||
| Saint-Petersburg State Budgetary Healthcare Institution "Oncological Dispensary of Moscow District" | Saint-Petersburg | 196247 | Russian Federation | Details | ||
| Non-State Healthcare Institution "Road Clinical Hospital at Saratov II Station" | Saratov | 410004 | Russian Federation | Details | ||
| State Budgetary Healthcare Institution of Stavropol region "Stavropol regional clinical oncology | Stavropol | 355047 | Russian Federation | Details | ||
| Institute for Oncology and Radiology of Serbia | Belgrade | 11000 | Serbia | Details | ||
| Military Medical Academy | Belgrade | 11000 | Serbia | Details | ||
| Clinic of Oncology-Clinical Center Nis | Nis | 18000 | Serbia | Details | ||
| Oncology Institute of Vojvodina | Sremska Kamenica | 21204 | Serbia | Details | ||
| Onkologicky ustav sv. Alzbety, s.r.o. | Bratislava | 812 50 | Slovakia | Details | ||
| Narodny Onkologicky Ustav | Bratislava | 833 10 | Slovakia | Details | ||
| GVI Oncology, Langenhoven Drive Oncology Centre | Port Elizabeth | Eastern CAPE | 6045 | South Africa | Details | |
| wits Clinical Research | Joannesburg | Gauteng | 2193 | South Africa | Details | |
| The Medical Oncology Centre of Rosebank | Johannesburg | Gauteng | 2196 | South Africa | Details | |
| Sandton Oncology Centre | Johannesburg | Gauteng | 2199 | South Africa | Details | |
| *Department of Medical Oncology, University of Pretoria & Steve Biko Academic Hospitals Complex | Pretoria | Gauteng | 0002 | South Africa | Details | |
| Eastleigh Breast Care Centre | Pretoria | Gauteng | 0081 | South Africa | Details | |
| Cape Town Oncology Trials | Kraaifontein | Western CAPE | 7570 | South Africa | Details | |
| GVI Rondebosch Oncology Centre-Rondebosch Medical Centre | Rondebosch | Western CAPE | 7700 | South Africa | Details | |
| National Cancer Institute | Ratchathewi | Bangkok | 10400 | Thailand | Details | |
| Udonthani Cancer Hospital | Amphur Muang | Udonthani | 41330 | Thailand | Details | |
| Faculty of Medicine, Chulongkorn University, Medical Oncology Unit | Bangkok | 10330 | Thailand | Details | ||
| Baskent University School of Medicine Adana Hospital | Adana | 01120 | Turkey | Details | ||
| Hacettepe Universitesi Tip Fakultesi | Ankara | 06100 | Turkey | Details | ||
| Uludag Universitesi Tip Fakultesi Ic Hastaliklari Anabilim Dali | Bursa | 16059 | Turkey | Details | ||
| Dicle University Medical Faculty | Diyarbakir | 21080 | Turkey | Details | ||
| Gaziantep University Medical Faculty | Gaziantep | 27310 | Turkey | Details | ||
| Istanbul Universitesi Onkoloji Enstitusu | Istanbul | 34093 | Turkey | Details | ||
| Municipal Institution "Chernivtsi Regional Clinical Oncology Center", Outpatient Department | Chernivtsi | 58013 | Ukraine | Details | ||
| Municipal Non-Profit Enterprise City Clinical Hospital No.4of Dnipro Regional Council, Department of | Dnipro | 49102 | Ukraine | Details | ||
| SI Institute of Medical Radiology n.a.S.P. Ilrygoriev of National Academy of Medical Science of | Kharkiv | 61024 | Ukraine | Details | ||
| Communal Non-Profit Enterprise "Regional Center of Oncology" | Kharkiv | 61070 | Ukraine | Details | ||
| Khmelnytskyi Regional Oncologic Dispensary | Khmelnytskyi | 29009 | Ukraine | Details | ||
| Municipal Enterprise 'Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional Council' | Kryvyi Rih | 50048 | Ukraine | Details | ||
| Municipal Non-Profit Enterprise of Kyiv Regional Council "Kyiv Regional Oncology Dispensary" | Kyiv | 04107 | Ukraine | Details | ||
| Lviv State Oncologic Regional Treatment and Diagnostic Center | Lviv | 79031 | Ukraine | Details | ||
| Municipal Institution Odesa Regional Clinical Hospital, Mammology Center | Odesa | 65025 | Ukraine | Details | ||
| Zakarpattia Regional Clinical Oncological Center | Uzhgorod | 88014 | Ukraine | Details | ||
| Municipal Non-profit Enterprise Podilsk Regional Oncology Centre of Vinnytsia Regional Council | Vinnytsia | 21029 | Ukraine | Details |