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| NCT ID | NCT02130557 |
| Title | A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Avillion Development 1 Limited |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | SWE | SVK | POL | NOR | NLD | ITA | ISR | HUN | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Pacific Cancer Medical Center, Inc. | Anaheim | California | 92801 | United States | Details | |
| Emory University Hospital | Atlanta | Georgia | 30322 | United States | Details | |
| The Emory Clinic | Atlanta | Georgia | 30322 | United States | Details | |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Kaiser Permanente Hawaii | Honolulu | Hawaii | 96819 | United States | Details | |
| Saint Alphonsus Regional Medical Center, Cancer Care Center | Boise | Idaho | 83706 | United States | Details | |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | United States | Details | |
| Saint Alphonsus Caldwell Cancer Care Center | Caldwell | Idaho | 83605 | United States | Details | |
| Saint Alphonsus Medical Center Nampa | Nampa | Idaho | 83686 | United States | Details | |
| University of Illinois Cancer Center | Chicago | Illinois | 60612 | United States | Details | |
| John H. Stroger, Jr. Hospital of Cook County | Chicago | Illinois | 60621 | United States | Details | |
| Indiana Blood and Marrow Transplantation | Indianapolis | Indiana | 46237 | United States | Details | |
| PHARMACY Department Franciscan St. Francis Health ATTN:Jill Leslie, Pharm D | Indianapolis | Indiana | 46237 | United States | Details | |
| Cancer Center of Acadiana at Lafayette General Medical Center | Lafayette | Louisiana | 70503 | United States | Details | |
| Lafayette General Medical Center | Lafayette | Louisiana | 70503 | United States | Details | |
| LSU Health Sciences Center-Shreveport | Shreveport | Louisiana | 71103 | United States | Details | |
| University Health Shreveport | Shreveport | Louisiana | 71103 | United States | Details | |
| Rcca Md Llc | Bethesda | Maryland | 20817 | United States | Details | |
| University of Massachusetts Memorial Medical Center, ONC/Research Pharmacy | Worcester | Massachusetts | 01655 | United States | Details | |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | United States | Details | |
| St. Joseph Mercy Hospital - Inpatient Pharmacy | Ann Arbor | Michigan | 48106 | United States | Details | |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | United States | Details | |
| St. Joseph Mercy-Brighton | Brighton | Michigan | 48114 | United States | Details | |
| St. Joseph Mercy-Canton | Canton | Michigan | 48188 | United States | Details | |
| Chelsea Community Hospital | Chelsea | Michigan | 48118-1370 | United States | Details | |
| St. John Hospital&Medical Center | Detroit | Michigan | 48236 | United States | Details | |
| St. John Hospital&Medical Center-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | 48236 | United States | Details | |
| Van Elslander Cancer Center, Pharmacy | Grosse Pointe Woods | Michigan | 48236 | United States | Details | |
| Minnesota Oncology Hematology, PA | Edina | Minnesota | 55435 | United States | Details | |
| Park Nicollet Frauenshuh Cancer center | Saint Louis Park | Minnesota | 55426 | United States | Details | |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | United States | Details | |
| North Mississippi Medical Center Hematology and Oncology Clinic | Tupelo | Mississippi | 38801 | United States | Details | |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | United States | Details | |
| NYU Winthrop Hospital - Oncology / Hematology department | Mineola | New York | 11501 | United States | Details | |
| NYU Winthrop Hospital - Pharmacy Department | Mineola | New York | 11501 | United States | Details | |
| Beth Israel Medical Center | New York | New York | 10003 | United States | Details | |
| University of Rochester Investigational Drug Pharmacy | Rochester | New York | 14642 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| FirstHealth Moore Regional Hospital | Pinehurst | North Carolina | 28374 | United States | Details | |
| FirstHealth Outpatient Cancer Center | Pinehurst | North Carolina | 28374 | United States | Details | |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | United States | Details | |
| UC Health Physicians Office South, | West Chester | Ohio | 45069 | United States | Details | |
| MUSC University Hospital | Charleston | South Carolina | 29425 | United States | Details | |
| MUSC University of South Carolina, Investigational Drug Services | Charleston | South Carolina | 29425 | United States | Details | |
| MUSC-Hollings Cancer Center | Charleston | South Carolina | 29425 | United States | Details | |
| GHS Cancer Institute | Easley | South Carolina | 29640 | United States | Details | |
| GHS Cancer Institute | Greenville | South Carolina | 29605 | United States | Details | |
| GHS Cancer Institute | Greenville | South Carolina | 29615 | United States | Details | |
| GHS Cancer Institute | Greer | South Carolina | 29650 | United States | Details | |
| GHS Cancer Institute | Seneca | South Carolina | 29672 | United States | Details | |
| GHS Cancer Institute | Spartanburg | South Carolina | 29307 | United States | Details | |
| The University of Texas, MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Utah Cancer Specialists | Murray | Utah | 84157 | United States | Details | |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Huntsman Cancer Hospital | Salt Lake City | Utah | 84112 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| HSHS St. Vincent Hospital Regional Cancer Center at HSHS St. Vincent Hospital | Green Bay | Wisconsin | 54301 | United States | Details | |
| HSHS St. Vincent Hospital | Green Bay | Wisconsin | 54301 | United States | Details | |
| HSHS St. Vincent Hospital Regional Cancer Center at HSHS St. Mary's Hospital Medical Center | Green Bay | Wisconsin | 54303 | United States | Details | |
| Froedtert Hospital and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| St George Hospital - Hematology Department | Kogarah | New South Wales | 2217 | Australia | Details | |
| Eastern Clinical Research Unit, Level 2 | Box Hill | Victoria | 3128 | Australia | Details | |
| UZ Ghent (University Hospital Ghent) | Ghent | 9000 | Belgium | Details | ||
| Department of Haematology at UZ Leuven (7 th Floor) | Leuven | 3000 | Belgium | Details | ||
| Hematology Department of CHU de Liège | Liège | 4000 | Belgium | Details | ||
| Hematology Department CHR Verviers | Verviers | 4800 | Belgium | Details | ||
| Horizon Health Network - The Moncton Hospital | Moncton | New Brunswick | E1C 6Z8 | Canada | Details | |
| Juravinski Cancer Centre | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| Lakeridge Health | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Hopital Maisonneuve-Rosemont | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Saskatoon Cancer Centre | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| CHU de Québec - Université Laval | Quebec | G1J 1Z4 | Canada | Details | ||
| Fakultní Nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
| Fakultní Nemocnice Hradec Králové | Hradec Králové | 500 05 | Czechia | Details | ||
| Fakultní nemocnice Olomouc | Olomouc | 775 20 | Czechia | Details | ||
| Všeobecná fakultní Nemocnice v Praze | Prague | 128 08 | Czechia | Details | ||
| Aalborg University Hospital | Aalborg | 9000 | Denmark | Details | ||
| Aarhus University Hospital | Aarhus | 8000 | Denmark | Details | ||
| Roskilde Hospital | Roskilde | 4000 | Denmark | Details | ||
| Helsinki University Central Hospital | Helsinki | 00029 HUS | Finland | Details | ||
| Oncologie Centre de Radiotherapie | Strasbourg | NC | 67000 | France | Details | |
| Institut Bergonié | Bordeaux | 33076 | France | Details | ||
| private Practice of Pr Philippe Rousselot | Le Chesnay | 78157 | France | Details | ||
| private Practice of Dr. Viviane Dubruille | Nantes cedex 1 | 44093 | France | Details | ||
| Hôpital L'Archet 1-CHU Nice | Nice | 06202 | France | Details | ||
| Institut de Cancérologie du Gard - Hématologie Clinique | Nimes | 30029 | France | Details | ||
| Pr Mauricette Michallet Centre Hospitalier Lyon Sud | Pierre Bénite | 69495 | France | Details | ||
| INSERM CIC 1402 - CHU Poitiers | Poitiers | 86021 | France | Details | ||
| Institut Universitaire du Cancer de Toulouse - Oncopole | Toulouse cedex 9 | 31059 | France | Details | ||
| Universitätsklinikum Bonn | Bonn | RP | 53105 | Germany | Details | |
| Uniklinikum Aachen | Aachen | 52074 | Germany | Details | ||
| Charité, CVK, Med. Klinik m.S Hämatologie und Onkologie | Berlin | 13353 | Germany | Details | ||
| Universitätsklinikum Freiburg, Klinik für Innere Medizin I | Freiburg | 79106 | Germany | Details | ||
| Universitätsklinikum Hamburg-Eppendorf, Onkologisches Zentrum | Hamburg | 20251 | Germany | Details | ||
| Universitätsklinikum Jena, Klinik für Innere Medizin II | Jena Lobeda-Ost | 07747 | Germany | Details | ||
| Schwerpunktpraxis für Hämatologie und Onkologie | Magdeburg | 39104 | Germany | Details | ||
| Semmelweis Egyetem I. Belgyógyászat | Budapest | 1083 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Központ, Belgyógyászati Inézet Hematológiai Tanszék | Debrecen | 4032 | Hungary | Details | ||
| Petz Aladár Megyei OktatóKórház, II. Belgyógyászati Osztály és Haematológiai Részleg | Györ | 9023 | Hungary | Details | ||
| Somogy Megyei Kaposi Mór Oktató Kórház | Kaposvár | 7400 | Hungary | Details | ||
| Szegedi Tudományegyetem, AOK, Szent-Györgyi Albert Klinikai Központ, II. sz. | Szeged | 6725 | Hungary | Details | ||
| Jász-Nagykun-Szolnok Megyei Hetényi, Géza Kórház-Rendelőintézet | Szolnok | 5000 | Hungary | Details | ||
| Hematology Department, Rambam Medical Centre | Haifa | 31096 | Israel | Details | ||
| Hematology Div. Davidoff Cancer Center, Rabin Medical Center | Petah-Tikva | 49100 | Israel | Details | ||
| Azienda Ospedaliero-Universitaria "Policlinico - Vittorio Emanuele" - P.O. G. Rodolico | Catania | CT | 95123 | Italy | Details | |
| USC Ematologia, A. O. Papa Giovanni XXIII | Bergamo | 24127 | Italy | Details | ||
| Policlinico S. Orsola - Malpighi, | Bologna | 40138 | Italy | Details | ||
| A.O. Brozu - P.O. Armando Businco | Cagliari | 09121 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Careggi | Firenze | 50134 | Italy | Details | ||
| IRCCS - AOU San Martino_IST, Ematologia 1 | Genova | 16132 | Italy | Details | ||
| Istituto Scientifico San Raffaele | Milano | 20132 | Italy | Details | ||
| Unità di Ricerca Clinica, U.O. Ematologia Adulti | Monza | 20900 | Italy | Details | ||
| A.O.U. Policlinico Università degli Studi di Napoli "Federico II" | Napoli | 80131 | Italy | Details | ||
| Dipartimento di ematologia | Reggio Calabria | 89124 | Italy | Details | ||
| ASL Roma 2 - Ospedale Sant'Eugenio | Roma | 00144 | Italy | Details | ||
| Hallym University Sacred Heart Hospital | Anyang-si | 14068 | Korea, Republic of | Details | ||
| Dong A University Hospital | Busan | 49201 | Korea, Republic of | Details | ||
| Keimyung University Dongsan Hospital | Daegu | 41931 | Korea, Republic of | Details | ||
| Chonbuk National University Hospital | Jeonju | 54907 | Korea, Republic of | Details | ||
| Kangbuk Samsung Hospital | Seoul | 03181 | Korea, Republic of | Details | ||
| Seoul St. Mary's Hospital of the Catholic University of Korea | Seoul | 06591 | Korea, Republic of | Details | ||
| Hospital Angeles del Pedregal (S.A. de C.V.) | Mexico City | DF | 10700 | Mexico | Details | |
| Monterrey International Research Center | Monterrey | Nuevo LEON | 64000 | Mexico | Details | |
| VU University Medical Center | Amsterdam | Noord Holland | 1081 HV | Netherlands | Details | |
| Klinische Farrnacologie en Apotheek | Amsterdam | Noord-holland | 1081 BT | Netherlands | Details | |
| Haukeland University Hospital Department of Hematology | Bergen | 5021 | Norway | Details | ||
| St. Olavs Hospital | Trondheim | 7006 | Norway | Details | ||
| Klinika Hematologii i Transplantologii Uniwersyteckie Centrum Kliniczne | Gdansk | Pomorskie | 80-214 | Poland | Details | |
| SPZOZ ZSM w Chorzowie Oddzial Hematologiczny | Chorzow | 41-500 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny im. A Mielęckiego, ŚUM w Katowicach | Katowice | 40032 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Hematologii | Kraków | 31501 | Poland | Details | ||
| SPSK, Klinika Hematoonkologii i Transplantacji Szpiku w Lublinie | Lublin | 20081 | Poland | Details | ||
| Universytet Medyczny im. Piastów Śląskich we Wrocławiu Katedra i | Wrocław | 50-367 | Poland | Details | ||
| Wojewódzki Szpital Specjalistyczny im M. Kopernika, Klinika Hematologii Uniwersytetu Medycznego | Łódź | 93510 | Poland | Details | ||
| National University Hospital, Main Building | Singapore | 119228 | Singapore | Details | ||
| Singapore General Hospital | Singapore | 169608 | Singapore | Details | ||
| Tan Tock Seng Hospital | Singapore | 308433 | Singapore | Details | ||
| Univerzitná Nemocnica Bratislava-Nemocnica sv. Cyrila a Metoda | Bratislava | 851 07 | Slovakia | Details | ||
| The Medical Oncology Centre of Rosebank | Johannesburg | Gauteng | 2196 | South Africa | Details | |
| Department of Medical Oncology, University of Pretoria and Steve Biko | Pretoria | Gauteng | 0002 | South Africa | Details | |
| Groenkloof Life hospital. | Pretoria | Gauteng | 0181 | South Africa | Details | |
| Department of Haematology | Cape Town | Western CAPE | 7935 | South Africa | Details | |
| Hospital (Universitari(o)) Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario La Princesa | Madrid | Málaga | 28006 | Spain | Details | |
| Hospital Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario Gregorio Marañón | Madrid | 28007 | Spain | Details | ||
| Hospital Ramón y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hospital Virgen de la Salud | Toledo | 45004 | Spain | Details | ||
| Hospital Clínico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Linköping University Hospital | Linköping | SE-581 85 | Sweden | Details | ||
| Skåne University Hospital | Lund | SE-221 85 | Sweden | Details | ||
| Karolinska University Hospital Solna | Stockholm | SE-171 76 | Sweden | Details | ||
| Norrlands University Hospital | Umeå | SE-901 85 | Sweden | Details | ||
| Akademiska Hospital | Uppsala | SE-751 85 | Sweden | Details | ||
| China Medical University Hospital | Taichung city | R.o.c. | 40447 | Taiwan | Details | |
| Chi-Mei Medical Center | Tainan City | R.o.c. | 710 | Taiwan | Details | |
| Mackay Memorial Hospital | Taipei City | R.o.c. | 10449 | Taiwan | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung City | 807 | Taiwan | Details | ||
| Division of Hematology, Department of Internal Medicine, Maharaj Nakorn Chiang Mai Hospital | Muang | Chiang MAI | 50200 | Thailand | Details | |
| King Chulalongkorn Memorial Hospital | Bangkok | 10330 | Thailand | Details | ||
| Phramongkutklao Hospital | Bangkok | 10400 | Thailand | Details | ||
| Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital | Bangkok | 10700 | Thailand | Details | ||
| MI "Cherkasy Regional Oncological Dispensary " of Cherkasy Regional Council | Cherkasy | 18009 | Ukraine | Details | ||
| Regional Clinical Hospital in Ivano-Frankivsk, Hematology Department | Ivano-Frankivsk | 76008 | Ukraine | Details | ||
| Khmelnytskyi Regional Hospital, Hematology Department | Khmelnytskyi | 29000 | Ukraine | Details | ||
| State Institution "National research center for radiation medicine of NAMS of Ukraine", | Kyiv | 03115 | Ukraine | Details | ||
| State Institution "National research center for radiation medicine of NAMS of Ukraine" | Kyiv | 03115 | Ukraine | Details | ||
| transplantation department of hemotology and transplantology division within Clinical Radiology | Kyiv | 03115 | Ukraine | Details | ||
| Chair of internal medicine #2. | Kyiv | 04112 | Ukraine | Details | ||
| Kyiv City Clinical Hospital #9, Hematology department #1, | Kyiv | 04112 | Ukraine | Details | ||
| State Institution "Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine" | Lviv | 79044 | Ukraine | Details | ||
| Catherine Lewis Centre, Hammersmith Hospital | London | Greater London | W12 0HS | United Kingdom | Details | |
| Linda McCartney Centre | Liverpool | Merseyside | L7 8XP | United Kingdom | Details | |
| Department of Clinical Haematology | Nottingham | Nottinghamshire | NG5 1PB | United Kingdom | Details | |
| Cancer & Haematology Centre, Churchill Hospital | Oxford | Oxfordshire | OX3 7LE | United Kingdom | Details | |
| Department of Haematology The Royal Hallamshire Hospital | Sheffield | South Yorkshire | S10 2JF | United Kingdom | Details | |
| Heartlands Hospital | Birmingham | WEST Midlands | B9 5SS | United Kingdom | Details | |
| St James's Institute of Oncology | Leeds | WEST Yorkshire | LS9 7TF | United Kingdom | Details | |
| Department of Haematology | Cardiff | CF14 4XW | United Kingdom | Details | ||
| The Hope Clinical Trials Facility | Leicester | LE1 5WW | United Kingdom | Details |