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| NCT ID | NCT02147990 |
| Title | TIGER-2: A Phase 2, Open-label, Multicenter, Safety and Efficacy Study of Oral CO-1686 as 2nd Line EGFR-directed TKI in Patients With Mutant EGFR Non-small Cell Lung Cancer (NSCLC) |
| Acronym | NSCLC |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Clovis Oncology, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | GBR | FRA | ESP | DEU | CHE | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCLA Medical Center | Alhambra | California | 91801 | United States | Details | |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | United States | Details | |
| Saint Jude Heritage Healthcare | Fullerton | California | 92835 | United States | Details | |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92093 | United States | Details | |
| Northridge Hospital Medical Center | Northridge | California | 91328 | United States | Details | |
| Cancer Care Associates | Redondo Beach | California | 90277 | United States | Details | |
| University of California Davis Medical Center | Sacramento | California | 95817 | United States | Details | |
| University of California San Francisco | San Francisco | California | 94115 | United States | Details | |
| Coastal Integrative Cancer Care | San Luis Obispo | California | 93401 | United States | Details | |
| Saint Mary's Regional Cancer Center | Grand Junction | Colorado | 81501-6132 | United States | Details | |
| Rocky Mountain Cancer Centers, LLP | Lone Tree | Colorado | 80218 | United States | Details | |
| Yale University School of Medicine | New Haven | Connecticut | 32135 | United States | Details | |
| Advanced Medical Specialties | Miami | Florida | 33176 | United States | Details | |
| Cleveland Clinic Florida | Weston | Florida | 33331 | United States | Details | |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | United States | Details | |
| University of Illinois Chicago | Chicago | Illinois | 60612 | United States | Details | |
| Illinois Cancer Specialists | Niles | Illinois | 60714 | United States | Details | |
| Beth Israel Comprehensive Cancer Center | Boston | Massachusetts | 02215 | United States | Details | |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | United States | Details | |
| Minnesota Oncology Hematology, P.A | Minneapolis | Minnesota | 55404 | United States | Details | |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Montefiore Medical Center | Bronx | New York | 10461 | United States | Details | |
| New York Oncology Hematology, PC | Latham | New York | 12110-2188 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | United States | Details | |
| Texas Oncology P.A. | Amarillo | Texas | 79106 | United States | Details | |
| USO - Texas Oncology P.A. | Arlington | Texas | 76014 | United States | Details | |
| Texas Oncology-Austin Central | Austin | Texas | 78705 | United States | Details | |
| Texas Oncology-Beaumont | Beaumont | Texas | 77702 | United States | Details | |
| Texas Oncology P.A. | Bedford | Texas | 76022 | United States | Details | |
| Texas Oncology P.A. | Dallas | Texas | 75246 | United States | Details | |
| Texas Oncology P.A. | Flower Mound | Texas | 75028 | United States | Details | |
| The Methodist Hospital | Houston | Texas | 77030 | United States | Details | |
| Texas Oncology - Plano East | Plano | Texas | 75075-7787 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98686 | United States | Details | |
| Yakima Valley Memorial Hospital, North Star Lodge | Yakima | Washington | 98902 | United States | Details | |
| Icon Cancer Centre | South Brisbane | New South Wales | 4101 | Australia | Details | |
| Royal North Shore Hospital | Sydney | New South Wales | 2065 | Australia | Details | |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
| Flinders Medical Centre | Bedford Park | South Australia | 5042 | Australia | Details | |
| Princess Margaret Hospital | Toronto | Ontario | M5G 2L7 | Canada | Details | |
| Centre Hospitalier Regional Universitaire (CHRU) de Besancon - L'Hopital Jean Minjoz | Besançon | Franche-comte | 25030 cedex | France | Details | |
| Hôpital Tenon | Paris | Ile-de-france | 75020 | France | Details | |
| Institut Gustave Roussy | Villejuif | Ile-de-France | 94805 | France | Details | |
| Institut de Cancérologie de l'Ouest - René Gauducheau | Saint Herblain cedex | PAYS DE LA Loire | France | Details | ||
| Centre Hospitalier Lyon Sud | Pierre Bénité cedex | Rhone-alpes | 69495 | France | Details | |
| Centre Hospitalier Universitaire Côte de Nacre | Caen | France | Details | |||
| Centre Hospitalier Universitaire Hôpital Nord | Marseille Cedex 20 | 13915 | France | Details | ||
| Asklepios Fachkliniken München-Gauting | Gauting | Bayern | 82131 | Germany | Details | |
| Klinikum Innenstadt LMU | München | Bayern | 80336 | Germany | Details | |
| Goethe-Universität Frankfurt am Main | Frankfurt am Main | Hessen | 60590 | Germany | Details | |
| Pius Hospital Oldenburg | Oldenburg | Niedersachsen | 26121 | Germany | Details | |
| Universitaetsklinikum Bonn - Zentrum fuer Innere Medizin - Medizinische Klinik und Poliklink III | Bonn | Nordrhein-westfalen | 53127 | Germany | Details | |
| Universitätsklinikum Essen | Essen | Nordrhein-westfalen | 45122 | Germany | Details | |
| Universitätsklinikum Köln | Köln | Nordrhein-westfalen | 50937 | Germany | Details | |
| LungenClinic Großhansdorf GmbH | Großhansdorf | Schleswig-holstein | 22927 | Germany | Details | |
| Evangelische Lungenklinik Berlin | Berlin | 13125 | Germany | Details | ||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Chungbuk National University Hospital | Chungju | Chungcheongbuk-do | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | Gyeonggi-do | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Incheon | Gyeonggi-do | 405-760 | Korea, Republic of | Details | |
| Dong-A University Hospital | Busan | Korea, Republic of | Details | |||
| Inha University Hospital | Incheon | 400-711 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul National University Hospital | Seoul | Korea, Republic of | Details | |||
| Seoul Saint Mary's Hospital | Seoul | Korea, Republic of | Details | |||
| Severance Hospital, Yonsei University Health System | Seoul | Korea, Republic of | Details | |||
| Antoni van Leeuwenhoek Hospital | Amsterdam | Noord-holland | 1066 CX | Netherlands | Details | |
| Vrije Universiteit Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
| Hospital Universitario Virgen del Rocio | Seville | Sevilla | 41013 | Spain | Details | |
| Hospital Universitari Germans Trias i Pujol | Badalona | Spain | Details | |||
| Hospital Vall d´Hebrón | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Quirón Dexeus | Barcelona | Spain | Details | |||
| Hospital Universitario La Paz | Madrid | Spain | Details | |||
| Centre Hospitalier Universitaire Vaudoise | Lausanne | Vaud | 1011 | Switzerland | Details | |
| Taipei Veterans General Hospital | Taipei | Taipei CITY | 11217 | Taiwan | Details | |
| Chang Gung Memorial Hospital Linkou | Taoyuan | Tao-Yuan | 33305 | Taiwan | Details | |
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Cambridge University Hospitals NHS Foundation Trust | Cambridge | England | CB2 0QQ | United Kingdom | Details | |
| Guy's and Saint Thomas NHS Foundation Trust | London | Greater London | SE1 9RT | United Kingdom | Details | |
| Royal Marsden Hospital | London | Greater London | SW3 6JJ | United Kingdom | Details | |
| Royal Marsden NHS Trust | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| University College Hospital | London | NW1 2PQ | United Kingdom | Details |