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| NCT ID | NCT02186821 |
| Title | Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE) |
| Acronym | SIGNATURE |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| St Joseph Heritage Healthcare St. Joseph Heritage | Santa Rosa | California | 94503 | United States | Details | |
| Sarah Cannon Research Institute | Denver | Colorado | 80218 | United States | Details | |
| Rocky Mountain Cancer Centers Dept of Rocky Mountain (2) | Greenwood Village | Colorado | United States | Details | ||
| Florida Cancer Specialists Florida Cancer Specialists (31 | Fort Myers | Florida | 33901 | United States | Details | |
| Northwestern University Northwestern (6) | Chicago | Illinois | 60611 | United States | Details | |
| Physicians Clinic of Iowa | Cedar Rapids | Iowa | 52403 | United States | Details | |
| Holy Cross Hospital Holy Cross (2) | Silver Spring | Maryland | 20910 | United States | Details | |
| Southeast Nebraska Oncology | Lincoln | Nebraska | 68510 | United States | Details | |
| Comprehensive Cancer Centers of Nevada CCC of Nevada (1) | Las Vegas | Nevada | 89109 | United States | Details | |
| Duke University Medical Center Seeley G. Mudd Bldg. | Durham | North Carolina | 27710 | United States | Details | |
| Wake Forest Baptist Health Health Sciences | Winston-Salem | North Carolina | 27157 | United States | Details | |
| Sanford Hematology Oncology | Fargo | North Dakota | 58122 | United States | Details | |
| Columbus Hematology and Oncology PA Columbus Hem and Onc (2) | Columbus | Ohio | 39705 | United States | Details | |
| Andrew and Patel Associates | Camp Hill | Pennsylvania | 17011 | United States | Details | |
| Rhode Island Hospital Rhode Island Hosp. (2) | Providence | Rhode Island | 02903 | United States | Details | |
| Sanford University of South Dakota Medical Center Sanford Clinical Research | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Oncology Consultants Oncology Group | Houston | Texas | 77024 | United States | Details | |
| MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) | Houston | Texas | 77030 | United States | Details | |
| Utah Cancer Specialists Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Swedish Cancer Institute Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| Aurora Research Institute | Milwaukee | Wisconsin | 53226 | United States | Details |