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| NCT ID | NCT02242942 |
| Title | A Study to Compare the Efficacy and Safety of Obinutuzumab + GDC-0199 Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | ROU | POL | NZL | ITA | HRV | GBR | FRA | EST | ESP | DNK | DEU | CHE | CAN | BRA | BGR | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | United States | Details | |
| City of Hope | Duarte | California | 91010 | United States | Details | |
| San Diego Pacific Hematology Assocates | Encinitas | California | 92024-1375 | United States | Details | |
| UC San Diego Health System | La Jolla | California | 92093 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | United States | Details | |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States | Details | |
| Joe Arrington Cancer Center | Lubbock | Texas | 79410 | United States | Details | |
| Hospital Italiano | Buenos Aires | C1181ACH | Argentina | Details | ||
| Liverpool Hospital | Liverpool | New South Wales | 2170 | Australia | Details | |
| Tweed Hospital | Tweed Heads | New South Wales | 2485 | Australia | Details | |
| The Townsville Hospital | Douglas | Queensland | 4814 | Australia | Details | |
| Princess Alexandra Hospital Woolloongabba; Clinical Hematology and Medical Oncology | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Royal Adelaide Hospital; Haematology Clinical Trials | Adelaide | South Australia | 5000 | Australia | Details | |
| Ashford Cancer Centre Research; Internal Medicine/Medical Oncology | Ashford | South Australia | 5035 | Australia | Details | |
| Box Hill Hospital | Box Hill | Victoria | 3128 | Australia | Details | |
| The Northern Hospital | Epping | Victoria | VIC 3076 | Australia | Details | |
| Monash Medical Centre; Haematology | Melbourne | Victoria | 3168 | Australia | Details | |
| Tiroler Landeskrankenanstalten Ges.M.B.H.; Innere Medizin Abt. Für Hämatologie & Onkologie | Innsbruck | 6020 | Austria | Details | ||
| Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Hämatologie & Hämostaseologie | Wien | 1090 | Austria | Details | ||
| Hanusch-Krankenhaus; Iii. Medizinische Abt. | Wien | 1140 | Austria | Details | ||
| Wilhelminenspital; I. Medizinische Abt. | Wien | 1160 | Austria | Details | ||
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | 90035-903 | Brazil | Details | |
| Instituto de Ensino e Pesquisa Sao Lucas - IEP | Sao Paulo | SP | 01236-030 | Brazil | Details | |
| Hospital Sírio-Libanês | Sao Paulo | SP | 01308-050 | Brazil | Details | |
| Hospital das Clinicas - FMUSP | Sao Paulo | SP | 05403-010 | Brazil | Details | |
| Hospital Santa Marcelina | Sao Paulo | SP | 08270-070 | Brazil | Details | |
| UMHAT Dr Georgi Stranski; Hematology | Pleven | 5800 | Bulgaria | Details | ||
| UMHAT " Sveti Georgi" Plovdiv - Clinic of Oncology and Hematology | Plovdiv | 4002 | Bulgaria | Details | ||
| University Hospital Sv.Georgi Clnic of Hematology; Hematology | Plovdiv | 4002 | Bulgaria | Details | ||
| University Multiprofile Hospital For Active Treatment "Sveti Ivan Rilski" EAD; clinical hematology | Sofia | 1431 | Bulgaria | Details | ||
| MHAT Hristo Botev; First Internal Department | Vratsa | 3000 | Bulgaria | Details | ||
| Tom Baker Cancer Centre; Dept of Medicine | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Queen Elizabeth II Health Sciences Centre; Oncology | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| University Hospital Center Zagreb; Haematology Department | Zagreb | 10000 | Croatia | Details | ||
| University Hospital Merkur Clinic for Internal Medicine/ Hematology | Zagreb | 10000 | Croatia | Details | ||
| Herlev Hospital | Herlev | 2730 | Denmark | Details | ||
| Rigshospitalet | København Ø | 2100 | Denmark | Details | ||
| Sjaellands Universitetshospital, Roskilde | Roskilde | 4000 | Denmark | Details | ||
| Sygehus Lillebælt, Vejle | Vejle | 7100 | Denmark | Details | ||
| North Estonia medical Centre; Hematology | Tallinn | 13419 | Estonia | Details | ||
| Tartu Uni Hospital; Hematology - Oncology Clinic | Tartu | 51014 | Estonia | Details | ||
| CHU Besançon - Hôpital Jean Minjoz | Besançon Cedex | 25030 | France | Details | ||
| Institut d'Hématologie de Basse Normandie | Caen | 14000 | France | Details | ||
| Chu Estaing; Hematologie Clinique Adultes | Clermont Ferrand | 63003 | France | Details | ||
| Hopital Henri Mondor | Creteil | 94000 | France | Details | ||
| CHU de Dijon - Hopital le Bocage | Dijon | 21000 | France | Details | ||
| CHU de Grenoble | Grenoble | 38043 | France | Details | ||
| Centre Jean Bernard | Le Mans | 72015 | France | Details | ||
| Centre Leon Berard; Departement Oncologie Medicale | Lyon | 69373 | France | Details | ||
| Hôpital Saint Eloi; Service d?Hématologie et Oncologie Clinique - Recherche Clinique | Montpellier | 34295 | France | Details | ||
| Hopital Hotel Dieu Et Hme;Hopital De Jour | Nantes | 44093 | France | Details | ||
| Hopital Saint Louis ; Service d Oncologie Medicale Fougere 6 (Pr Misset) | Paris | 75475 | France | Details | ||
| Hopital Pontchaillou; Hematologie Clinique | Rennes | 35033 | France | Details | ||
| Centre Henri Becquerel; Hematologie | Rouen | 76038 | France | Details | ||
| CH de Toulon Hôpital Sainte Musse | Toulon | 83056 | France | Details | ||
| Institut Gustave Roussy - Hematologie | Villejuif | 94805 | France | Details | ||
| Uniklinik RWTH Aachen; Klinik IV; Klinik Hämatologie, Onkologie, Hämostaseologie und Stamm. | Aachen | 52074 | Germany | Details | ||
| Gesundheitszentrum St. Marien GmbH; Med. II, Hämatologie/Onkologie | Amberg | 92224 | Germany | Details | ||
| Charite - Universitätsmedizin Berlin | Berlin | 12203 | Germany | Details | ||
| Charite - Campus Virchow-Klinikum | Berlin | 13353 | Germany | Details | ||
| BAG Freiberg-Richter, Jacobasch, Illmer, Wolf; Gemeinschaftspraxis Hämatologie-Onkologie | Dresden | 01307 | Germany | Details | ||
| Uniklinikum "Carl Gustav Carus"; Med. Klinik 1; Hämatologie, Zelltherapie und Medizinische Onkologie | Dresden | 01307 | Germany | Details | ||
| Universitätsklinikum Essen; Klinik für Hämatologie | Essen | 45122 | Germany | Details | ||
| Klinik Esslingen; Klinik für Allgemeine Innere Medizin, Onkologie/Haematologie | Esslingen | 73730 | Germany | Details | ||
| Klinikum Frankfurt/Oder | Frankfurt/Oder | 15236 | Germany | Details | ||
| Uniklinikum Freiburg | Freiburg | 79106 | Germany | Details | ||
| Uni Göttingen, Georg-August-Universität; Klinik für Hämatologie und Medizinische Onkologie | Göttingen | 37075 | Germany | Details | ||
| Universitaetsklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| Stiftung Kathol. Krankenhaus Marienhospital Herne Klinik Mitte | Herne | 44625 | Germany | Details | ||
| Praxisklinik für Hämatologie und Onkologie Koblenz | Koblenz | 56068 | Germany | Details | ||
| Universitätsklinikum Köln; Innere Medizin I; Onkologie, Hämatologie | Köln | 50931 | Germany | Details | ||
| Tagesklinik Landshut; Hämatologie/Onkologie | Landshut | 84028 | Germany | Details | ||
| Klinikum rechts der Isar der Technischen Universität München | Munchen | 81675 | Germany | Details | ||
| Klinikum Schwäbisch Gmünd | Mutlangen | 73557 | Germany | Details | ||
| Kliniken Maria Hilf GmbH Innere Medizin I | Mönchengladbach | 41063 | Germany | Details | ||
| München Klinik Schwabing; Klinik für Hämatologie, Onkologie, Immunologie | München | 80804 | Germany | Details | ||
| Klinikum der Universität München, Campus Großhadern; Medizinische Klinik und Poliklinik III | München | 81377 | Germany | Details | ||
| Gemeinschaftspraxis Dr. med. Holger Klaproth | Neunkirchen/Saar | 66538 | Germany | Details | ||
| Brüderkrankenhaus St. Josef Paderborn | Paderborn | 33098 | Germany | Details | ||
| Krankenhaus Barmherzige Bruder Regensburg | Regensburg | 93049 | Germany | Details | ||
| Marienhospital | Stuttgart | 70199 | Germany | Details | ||
| Robert-Bosch-Krankenhaus | Stuttgart | 70376 | Germany | Details | ||
| Universitätsklinikum Tübingen | Tübingen | 72076 | Germany | Details | ||
| Universtitätsklinikum Ulm; Klinik für Innere Medizin III | Ulm | 89081 | Germany | Details | ||
| Medizinisches Versorgungszentrum Nuklearmedizin-Strahlentherapie-Onkologie | Weiden | 92367 | Germany | Details | ||
| Arcispedale S. Anna; Sezione Di Ematologia | Ferrara | Emilia-Romagna | 44100 | Italy | Details | |
| Ospedali Riuniti Papardo-Piemonte; Struttura Complessa Di Ematologia | Messina | Lazio | 98158 | Italy | Details | |
| Uni Cattolica; Divisione Di Ematologia | Roma | Lazio | 00168 | Italy | Details | |
| AOU Città della Salute e della Scienza di Torino - Presidio Le Molinette | Torino | Lazio | 10126 | Italy | Details | |
| Ospedale San Raffaele | Milano | Lombardia | 20132 | Italy | Details | |
| Az. Osp. S. Maria; Dept. Di Oncologia Medica | Terni | Umbria | 05100 | Italy | Details | |
| Ospedale dell' Angelo; U.O. Ematologia | Venezia Mestre | Veneto | 30174 | Italy | Details | |
| Hospital General de Culiacan | Culiacan | Sinaloa | 80230 | Mexico | Details | |
| Canterbury Health Laboratories; Haematology | Christchurch | 8011 | New Zealand | Details | ||
| Dunedin Hospital | Dunedin | New Zealand | Details | |||
| Midcentral District Health Board | Palmerston North | 4442 | New Zealand | Details | ||
| Wellington Hospital | Wellington | 6012 | New Zealand | Details | ||
| Uniwersytecki Szpital Kliniczny w Bia?ymstoku, Klinika Hematologii z Pododdzia?em Chorob Naczyn | Bialystok | 15-2 | Poland | Details | ||
| Samodzielny Public Zaklad | Chorzów | 41-500 | Poland | Details | ||
| Wojewódzki Szpital Specjalistyczny im.Miko?ajaKopernika;KlinikaHematologiiUniwersytetuMedycznego | Lodz | 9351 | Poland | Details | ||
| Wojewodzki Szpital Specjalistyczny im. J. Korczaka; Oddzia? Chorób Wewnetrznych/Hematologiczny | Slupsk | 76-200 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny Nr 1 we Wroc?awiu; Klinika Hematologii | Wroclaw | 5036 | Poland | Details | ||
| Fundeni Clinical Inst. ; Hematology Dept | Bucharest | 022328 | Romania | Details | ||
| Institutul Regional de Oncologie Iasi; Clinica de Hematologie | Iasi | 700483 | Romania | Details | ||
| Spitalul Clinic Judetean de Urgenta Targu-Mures; compartiment Hematologie | Targu-mures | 540136 | Romania | Details | ||
| SBEI of HPE ?Bashkir State Medical University? of MoH RF | UFA | Baskortostan | 450000 | Russian Federation | Details | |
| Moscow State Budgetary Healthcare Institution | Moscow | Moskovskaja Oblast | 123182 | Russian Federation | Details | |
| Regional Clinical Hospital N.A. Semashko; Hematology | Nizhny Novgorod | Niznij Novgorod | 603126 | Russian Federation | Details | |
| Rostov State Medical Uni ; Hematology | Rostov-na-donu | Rostov | 344022 | Russian Federation | Details | |
| Republican Clinical Oncologic Dispensary of Republic Of Tatarstan | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| Penza Regional Oncology Dispensary | Penza | 440071 | Russian Federation | Details | ||
| Clinical MSCh No1 | Perm | 614077 | Russian Federation | Details | ||
| Complejo Hospitalario de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitario de Canarias;servicio de Hematologia | La Laguna | Tenerife | 38320 | Spain | Details | |
| Hospital del Mar; Servicio de Hematologia | Barcelona | 08003 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron; Servicio de Hematologia | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic i Provincial; Servicio de Hematología y Oncología | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario de la Princesa; Servicio de Hematologia | Madrid | 28006 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Ramón y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Univ. 12 de Octubre; Servicio de Hematologia | Madrid | 28041 | Spain | Details | ||
| Hospital Clinico Universitario de Salamanca;Servicio de Hematologia | Salamanca | 37007 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Complejo Hospitalario de Toledo- H. Virgen de la Salud; Servicio de Hematología | Toledo | 45004 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia | Valencia | 46010 | Spain | Details | ||
| Hospital Arnau de Vilanova (Valencia) Servicio de Hematologia | Valencia | 46015 | Spain | Details | ||
| Inselspital Bern; Hämatologie und Hämatologisches Zentrallabor | Bern | 3010 | Switzerland | Details | ||
| Luzerner Kantonsspital, Hämatologie | Luzern | 6000 | Switzerland | Details | ||
| Universitätsspital Zürich Medizin Hämatologie; Klinik für Hämatologie | Zürich | 8091 | Switzerland | Details | ||
| Birmingham Heartlands Hospital | Birmingham | B9 5SS | United Kingdom | Details | ||
| Boston Pilgrim Hospital | Boston,Lincolnshire | PE21 9QS | United Kingdom | Details | ||
| Western General Hospital; Department of Haematology | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| Lincoln County Hospital | Lincoln | LN2 5QY | United Kingdom | Details | ||
| University Hospital Southampton NHS Foundation Trust | Southhampton | SO16 6YD | United Kingdom | Details |