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| NCT ID | NCT02273973 |
| Title | Study of Neoadjuvant Letrozole + GDC-0032 Versus Letrozole + Placebo in Post-Menopausal Women With Breast Cancer (LORELEI) |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Genentech, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | POL | ITA | HUN | GBR | FRA | ESP | DEU | CZE | CHE | BRA | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Breastlink Med Group Inc | Santa Ana | California | 92705 | United States | Details | |
| MGH Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| MSKCC at Basking Ridge | Basking Ridge | New Jersey | 07920 | United States | Details | |
| MSKCC @ Commack | Commack | New York | 11725 | United States | Details | |
| MSKCC @ West Harrison | Harrison | New York | 10604 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center; Hematology/Oncology | New York | New York | 10065 | United States | Details | |
| MSKC @ Rockville | Rockville Centre | New York | 11570 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Kinghorn Cancer Centre; St Vincents Hospital | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Newcastle Mater Misericordiae Hospital; Oncology | Waratah | New South Wales | 2298 | Australia | Details | |
| Victorian Breast and Oncology Care | East Melbourne | Victoria | Australia | Details | ||
| Cabrini Medical Centre; Oncology | Malvern | Victoria | 3144 | Australia | Details | |
| Fiona Stanley Hospital | Murdoch | Western Australia | 6150 | Australia | Details | |
| Lkh-Univ. Klinikum Graz; Klinik Für Gynäkologie | Graz | 8036 | Austria | Details | ||
| LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie | Graz | 8036 | Austria | Details | ||
| Tiroler Landeskrankenanstalten Ges.M.B.H.; Abt. Für Gynäkologie | Innsbruck | 6020 | Austria | Details | ||
| Ordensklinikum Linz Barmherzige Schwestern ; Abt. f. Allgemein- und Viszeralchirurgie | Linz | 4010 | Austria | Details | ||
| Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt. | Salzburg | 5020 | Austria | Details | ||
| Brustzentrum - Ordination Dr. Wette | St. Veit/Glan | 9300 | Austria | Details | ||
| Klinikum Kreuzschwestern Wels; Iii. Interne Abt. | Wels | 4600 | Austria | Details | ||
| Medizinische Universität Wien; Univ.Klinik für Chirurgie - Abt. für Allgemeinchirurgie | Wien | 1090 | Austria | Details | ||
| Medizinische Universität Wien; Univ.Klinik für Frauenheilkunde - Klinik für Gynäkologie | Wien | 1090 | Austria | Details | ||
| Krankenhaus Der Stadt Wien-Hietzing; Abt. Für Gynäkologie U. Geburtshilfe | Wien | 1130 | Austria | Details | ||
| Institut Jules Bordet | Brussels | 1000 | Belgium | Details | ||
| CHU Brugmann (Victor Horta) | Bruxelles | 1020 | Belgium | Details | ||
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| UZ Antwerpen | Edegem | 2650 | Belgium | Details | ||
| Clinique Ste-Elisabeth | Namur | 5000 | Belgium | Details | ||
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Clinica de Neoplasias Litoral | Itajai | SC | 88301-220 | Brazil | Details | |
| Hospital de Cancer de Barretos | Barretos | SP | 14784-400 | Brazil | Details | |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Sao Paulo | SP | 01246-000 | Brazil | Details | |
| Instituto Brasileiro De Controle Do Câncer - IBCC; Laboratório De Patologia | São Paulo | SP | 03102-002 | Brazil | Details | |
| Hospital Clinico Vina del Mar | Viña del Mar | 2520612 | Chile | Details | ||
| Fakultni Nemocnice Hradec Kralove; Dept of Radiotherapy & Oncology | Hradec Kralove | 500 05 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| MULTISCAN, s.r.o., Radiologicke centrum Pardubice | Pardubice | 532 03 | Czechia | Details | ||
| Oblastni nemocnice Pribram | Pribram | 261 01 | Czechia | Details | ||
| Hospital Oncologia; Oncology | Salvador | 01101 | El Salvador | Details | ||
| Centre Jean Perrin; Division De Recherche Clinique | Clermont Ferrand | 63011 | France | Details | ||
| Centre Jean Bernard | Le Mans | 72015 | France | Details | ||
| Institut Curie; Oncologie Medicale | Paris | 75231 | France | Details | ||
| Hopital Saint Louis; Service Onco Thoracique | Paris | 75475 | France | Details | ||
| Centre Rene Huguenin; ONCOLOGIE GENETIQUE | Saint Cloud | 92210 | France | Details | ||
| CHI de Toulon - Hôpital Sainte Musse | Toulon | 83056 | France | Details | ||
| Institut de Cancérologie de Lorraine | Vandoeuvre-Les-Nancy | 54519 | France | Details | ||
| Praxisklinik Krebsheilkunde für Frauen / Brustzentrum (Dres. Kittel/Klare) | Berlin | 10367 | Germany | Details | ||
| Studienzentrum Berlin City | Berlin | 14169 | Germany | Details | ||
| Onkologische Schwerpunktpraxis Bielefeld | Bielefeld | 33604 | Germany | Details | ||
| Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden | Dresden | 01307 | Germany | Details | ||
| Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum | Essen | 45136 | Germany | Details | ||
| Evangelische Kliniken Gelsenkirchen GmbH; Brustzentrum | Gelsenkirchen | 45879 | Germany | Details | ||
| Universitätsklinikum Hamburg-Eppendorf (UKE); Klinik und Poliklinik für Gynäkologie | Hamburg | 20246 | Germany | Details | ||
| Medizinische Hochschule Hannover, Klinik für Frauenheilkunde und Geburtshilfe | Hannover | 30625 | Germany | Details | ||
| Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Frauenheilkunde und Geburtshilfe | Lübeck | 23538 | Germany | Details | ||
| Rotkreuzklinikum München; Frauenklinik | Muenchen | 80637 | Germany | Details | ||
| Universitätsklinikum Münster; Klinik für Frauenheilkunde und Geburtshilfe | Münster | 48149 | Germany | Details | ||
| Universitätsklinikum Ulm Am Michelsberg; Frauenklinik | Ulm | 89075 | Germany | Details | ||
| Marien-Hospital Witten; Frauenklinik Brustzentrum | Witten | 58452 | Germany | Details | ||
| Grupo Angeles | Guatemala City | 01015 | Guatemala | Details | ||
| Centro Oncológico Sixtino / Centro Oncológico SA | Guatemala | 01010 | Guatemala | Details | ||
| Szent Margit Hospital; Dept. of Oncology | Budapest | 1032 | Hungary | Details | ||
| Debreceni Egyetem, Klinikai Kozpont, Onkologiai Klinika | Debrecen | 4032 | Hungary | Details | ||
| Bacs-Kiskun Megyei Korhaz, SZTE AOK Oktato Korhaza, Onkoradiologiai Kozpont | Kecskemet | 6000 | Hungary | Details | ||
| B-A-Z County Hospital | Miskolc | 3526 | Hungary | Details | ||
| Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika | Szeged | 6720 | Hungary | Details | ||
| Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica | Bologna | Emilia-Romagna | 40138 | Italy | Details | |
| Ospedale degli Infermi | Rimini | Emilia-Romagna | 47923 | Italy | Details | |
| Uni Degli Studi Di Genova ; Clinica Di Medicina Interna Ad Indirizzo Oncologico | Genova | Liguria | 16132 | Italy | Details | |
| ASST DI CREMONA; Dip. Medicina - S.C. Oncologia | Cremona | Lombardia | 26100 | Italy | Details | |
| Ospedale Per Acuti Mater Salutis Di Legnago | Legnago | Lombardia | 37045 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | Milano | Lombardia | 20133 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO); Ricerca Di Senologia Medica | Milano | Lombardia | 20141 | Italy | Details | |
| National Cancer Center; Medical Oncology | Gyeonggi-do | 410-769 | Korea, Republic of | Details | ||
| Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology | Seoul | 03080 | Korea, Republic of | Details | ||
| Yonsei University Severance Hospital; Medical Oncology | Seoul | 120-752 | Korea, Republic of | Details | ||
| Samsung Medical Centre; Division of Hematology/Oncology | Seoul | 135-710 | Korea, Republic of | Details | ||
| Centro Estatal de Cancerología | Chihuahua | 31000 | Mexico | Details | ||
| Instituto Nacional De Cancerologia; Oncology; Tumores Mamarios | Distrito Federal | 14000 | Mexico | Details | ||
| Consultorio de Medicina Especializada; Dentro de Condominio San Francisco | Mexico City | 03100 | Mexico | Details | ||
| Centro Oncologico America | Panama | 0834-02723 | Panama | Details | ||
| Hospital Nacional Cayetano Heredia; Hematology - Oncology | Lima | 31 | Peru | Details | ||
| Oncosalud Sac; Oncología | Lima | 41 | Peru | Details | ||
| Clinica Internacional, Sede San Borja; Unidad de Investigacion de Clínica Internacional | Lima | Lima 41 | Peru | Details | ||
| Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii | Bydgoszcz | 85-796 | Poland | Details | ||
| Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii | Gdańsk | 80-952 | Poland | Details | ||
| Wojewódzki Szpital Specjalistyczny im. M. Kopernika; Oddział Chemioterapii | Lodz | 93-513 | Poland | Details | ||
| Europejskie Centrum Zdrowia Otwock Szpital im. Fryderyka Chopina, Klinika Onkologii | Otwock | 05-400 | Poland | Details | ||
| Wielkopolskie Centrum Onkologii; im. Marii Skłodowskiej-Curie | Poznan | 61-866 | Poland | Details | ||
| Cent.Onkologii-Instytut im. M. S-Curie, Klinika Now. Piersi i Chirurgii Rekon | Warszawa | 02-781 | Poland | Details | ||
| IPO de Lisboa; Servico de Oncologia Medica | Lisboa | 1099-023 | Portugal | Details | ||
| Centro Clinico Champalimaud; Oncologia Medica | Lisboa | 1400-038 | Portugal | Details | ||
| IPO do Porto; Servico de Oncologia Medica | Porto | 4200-072 | Portugal | Details | ||
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia | Santiago de Compostela | LA Coruña | 15706 | Spain | Details | |
| Instituto Universitario Dexeus; Servicio de Oncología | Barcelona | 08028 | Spain | Details | ||
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Institut Catala d Oncologia Hospital Duran i Reynals | Barcelona | 08908 | Spain | Details | ||
| Hospital San Pedro De Alcantara; Servicio de Oncologia | Caceres | 10003 | Spain | Details | ||
| Hospital Provincial de Castellon; Servicio de Oncologia | Castellon | 12002 | Spain | Details | ||
| Hospital Universitari de Girona Dr. Josep Trueta; Servicio de Oncologia | Girona | 17007 | Spain | Details | ||
| Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia | Jaen | 23007 | Spain | Details | ||
| Hospital Universitari Arnau de Vilanova de Lleida; Servicio de Oncologia | Lerida | 25198 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Centro Integral Oncologico Clara Campal (CIOCC); Dirección Médica | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario de Fuenlabrada; Servicio de Oncologia | Madrid | 28943 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Hospital Clinico Universitario; Oncologia | Valencia | 46010 | Spain | Details | ||
| Hospital Arnau de Vilanova (Valencia) Servicio de Oncologia | Valencia | 46015 | Spain | Details | ||
| Fundación IVO | Valencia | 46980 | Spain | Details | ||
| Kantonsspital Baden; Frauenklinik | Baden | 5405 | Switzerland | Details | ||
| Kantonsspital Graubünden;Onkologie und Hämatologie | Chur | 7000 | Switzerland | Details | ||
| Fondazione Oncologia Lago Maggiore | Locarno | 6600 | Switzerland | Details | ||
| Royal Bournemouth General Hospital; Oncology | Bournemouth | BH7 7DW | United Kingdom | Details | ||
| Frimley Park Hospital; Breast Resaerch Team | Camberley | GU16 7UJ | United Kingdom | Details | ||
| Beatson West of Scotland Cancer Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| Christie Hospital | Manchester | M20 3BG | United Kingdom | Details |