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| NCT ID | NCT02322281 |
| Title | TIGER-3 Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet Chemotherapy |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Clovis Oncology, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | United States | Details | |
| City of Hope Cancer Center | Duarte | California | 91010 | United States | Details | |
| Saint Joseph Heritage Healthcare | Fullerton | California | 92835 | United States | Details | |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92093-0698 | United States | Details | |
| Cancer Care Associates Medical Group, Inc. | Redondo Beach | California | 90277 | United States | Details | |
| Sutter Cancer Center | Sacramento | California | 95816 | United States | Details | |
| University of California, San Francisco Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | United States | Details | |
| Central Coast Medical Oncology Corporation | Santa Maria | California | 93454 | United States | Details | |
| University of California at Los Angeles | Santa Monica | California | 90404 | United States | Details | |
| Stanford University School of Medicine | Stanford | California | 94305 | United States | Details | |
| The Oncology Institute of Hope and Innovation | Whittier | California | 90603 | United States | Details | |
| Sylvester Comprehensive Cancer Center (UMHC) | Deerfield Beach | Florida | 33442 | United States | Details | |
| University of Florida Health Science Center | Gainesville | Florida | 32608 | United States | Details | |
| Memorial Healthcare System | Pembroke Pines | Florida | 33028 | United States | Details | |
| Northside Hospital | Atlanta | Georgia | 30341 | United States | Details | |
| North Shore University Health System | Evanston | Illinois | 60201 | United States | Details | |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | United States | Details | |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | United States | Details | |
| Regional Cancer Care Associates, LLC | East Brunswick | New Jersey | 08816 | United States | Details | |
| Regional Cancer Care Associates | Morristown | New Jersey | 07962 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| The Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | United States | Details | |
| Providence Health and Services | Portland | Oregon | 97223 | United States | Details | |
| Oregon Health & Science University (OHSU) - Knight Cancer Institute | Portland | Oregon | 97239 | United States | Details | |
| University of Pittsburgh Cancer Institute (UPMC) | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22903 | United States | Details | |
| Virginia Cancer Institute | Richmond | Virginia | 23230 | United States | Details | |
| Royal North Shore Hospital | Saint Leonards | New South Wales | 2065 | Australia | Details | |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
| Flinders Medical Centre | Bedford Park | South Australia | 5042 | Australia | Details | |
| Hopital Hautepierre (CHU) de Strasbourg | Strasbourg | Alsace | 67091 | France | Details | |
| Centre François Baclesse | Caen | Basse-Normandie | 14076 | France | Details | |
| Centre Hospitalier Universitaire de Rennes, Hôpital Pontchaillou | Rennes | Bretagne | 35033 | France | Details | |
| Centre Hospitalier Intercommunal Créteil | Créteil | Ile-de-France | 94010 | France | Details | |
| Hôpital Bichat-Claude Bernard | Paris | Ile-de-France | 75018 | France | Details | |
| CHRU de Limoges - Hôpital Dupuytren | Limoges | Limousin | 87042 | France | Details | |
| CHRU de Lille - Hôpital Calmette | Lille | Nord Pas-de-Calais | 59037 | France | Details | |
| L'Assistance Publique - Hopitaux de Marseille | Marseille | Provence Alpes Cote D'Azur | 13009 | France | Details | |
| Centre Léon Bérard | Lyon | 69373 | France | Details | ||
| Asklepios Fachkliniken München-Gauting | Gauting | Baden-Wuerttemberg | 82131 | Germany | Details | |
| Thoraxklinik Heidelberg gGmbH | Heidelberg | Baden-Wuerttemberg | 69126 | Germany | Details | |
| LMU - Klinikum der Universität München | München | Bayern | 80336 | Germany | Details | |
| Pius Hospital Oldenburg | Oldenburg | Niedersachen | 26121 | Germany | Details | |
| Johannes-Wesling-Klinikum Minden | Minden | Nordrhein-westfalen | 32429 | Germany | Details | |
| LungenClinic Großhansdorf GmbH | Großhansdorf | Schleswig-Holstein | 22927 | Germany | Details | |
| A.O.U. San Luigi Gonzaga di Orbassano | Orbassano | Torino | 10043 | Italy | Details | |
| Azienda Ospedaliero-Universitaria Careggi | Firenze | 50139 | Italy | Details | ||
| IRCCS Azienda Ospedaliera Universitaria San Martino - IST | Genova | 16132 | Italy | Details | ||
| Ospedale Civile di Livorno | Livorno | 57124 | Italy | Details | ||
| Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| Azienda Ospedaliera di Perugia | Perugia | 06132 | Italy | Details | ||
| Chungbuk National University Hospital | Cheongju-si | Cheungcheongbuk-do | 361-712 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 463-707 | Korea, Republic of | Details | |
| The Catholic University of Korea Saint Vincent's Hospital | Suwon | Gyeonggi | 442-723 | Korea, Republic of | Details | |
| Chonnam National University Hwasun Hospital | Hwasun-gun | Jeollanam-do | 519-809 | Korea, Republic of | Details | |
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 138-736 | Korea, Republic of | Details | ||
| Academisch Ziekenhuis Maastricht | Maastricht | Limburg | 6229 HX | Netherlands | Details | |
| Antoni van Leeuwenhoek Hospital | Amsterdam | Noord-Holland | 1066 CX | Netherlands | Details | |
| Universitair Medisch Centrum Groningen | Groningen | 9700 RB | Netherlands | Details | ||
| Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital de Mataró | Mataró | Barcelona | 08034 | Spain | Details | |
| Institut Universitari Dexeus | Barcelona | 08028 | Spain | Details | ||
| Hospital Universitari Vall D'Hebron | Barcelona | 08035 | Spain | Details | ||
| Fundacion Jimenez Diaz (Clinica de la Concepcion) (UAM -FJD) | Madrid | 28040 | Spain | Details | ||
| Hospital Regional Universitario Carlos Haya | Málaga | 29010 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Cheng-Kung University Hospital | Tainan | 70403 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| University College London Hospitals | London | England | NW1 2BU | United Kingdom | Details | |
| Guy's and Saint Thomas NHS Foundation Trust | London | England | SE1 9RT | United Kingdom | Details | |
| Royal Marsden NHS Trust | London | England | SW3 6JJ | United Kingdom | Details | |
| The Christie NHS Foundation Trust | Manchester | England | M20 4BX | United Kingdom | Details |