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| NCT ID | NCT02348489 |
| Title | SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Astex Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | SWE | ROU | POL | NLD | ITA | HUN | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CAN | BGR | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Cancer Center | Scottsdale | Arizona | 85259-5499 | United States | Details | |
| Scripps Cancer Center | La Jolla | California | United States | Details | ||
| University of Southern California | Los Angeles | California | 90033 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| University of Kansas Medical Center | Westwood | Kansas | 66160 | United States | Details | |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55454 | United States | Details | |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | United States | Details | |
| John Theurer Cancer Center at Hackensack | Hackensack | New Jersey | 07601 | United States | Details | |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87131 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Weill Cornell Medical College | New York | New York | 10021 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10065 | United States | Details | |
| Stony Brook University Medical Center | Stony Brook | New York | 11790 | United States | Details | |
| Duke Cancer Center | Durham | North Carolina | United States | Details | ||
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | United States | Details | |
| University Hospitals Monarch Medical Center | Cleveland | Ohio | United States | Details | ||
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| Temple University | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Wisconsin | Madison | Wisconsin | 53792 | United States | Details | |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Concord Repatriation General Hospital | Concord | New South Wales | 2139 | Australia | Details | |
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia | Details | |
| Monash Medical Centre | Clayton | Victoria | 3168 | Australia | Details | |
| Austin Health | Heidelberg | Victoria | Australia | Details | ||
| Medizinische Universität Graz | Graz | Styria | Austria | Details | ||
| Hanusch Krankenhaus Wiener Gebietskrankenkasse | Wien | Vienna | Austria | Details | ||
| Grand Hôpital de Charleroi | Charleroi | Hainaut | 6061 | Belgium | Details | |
| UZ Gent | Ghent | Oost-vlaanderen | 9000 | Belgium | Details | |
| Algemeen Ziekenhuis Sint-Jan | Brugge | West-vlaanderen | 8000 | Belgium | Details | |
| UMHAT 'Sveti Georgi' EAD | Plovdiv | Bulgaria | Details | |||
| Multiprofile Hospital for Active Treatment "Sveta Marina'' EAD | Varna | Bulgaria | Details | |||
| Tom Baker Cancer Center | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| University of Alberta Hospital | Edmonton | Alberta | 76B 2B7 | Canada | Details | |
| Vancouver General Hospital | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
| The Ottawa Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Princess Margaret Hospital | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Sunnybrook Health Sciences Centre | Toronto | Ontario | Canada | Details | ||
| Fakultní nemocnice Brno | Brno | Jihormoravsky KRAJ | Czechia | Details | ||
| Všeobecná fakultní nemocnice v Praze | Praha 2 | Praha | Czechia | Details | ||
| Fakultní nemocnice Královské Vinohrady | Praha 10 | Praha 10 | Czechia | Details | ||
| Aarhus University Hospital | Aarhus | 8000 | Denmark | Details | ||
| Rigshospitalet-Copenhagen University Hospital | Copenhagen | Denmark | Details | |||
| Odense University Hospital | Odense | Denmark | Details | |||
| Tampere University Hospital | Tampere | Southern Finland | Finland | Details | ||
| Helsinki University Central Hospital | Helsinki | Finland | Details | |||
| GHR Mulhouse Sud-Alsace | Mulhouse Cedex | Alsace | France | Details | ||
| Hôpital Hôtel-Dieu | Bayonne | Aquitaine | France | Details | ||
| Centre Henri-Becquerel | Rouen Cedex 1 | Haute-normandie | France | Details | ||
| Hôpital Saint Louis | Paris Cedex 10 | Ile-de-france | 75010 | France | Details | |
| CHRU de Limoges - Hôpital Dupuytren | Limoges Cedex | Limousin, Lorraine | 87000 | France | Details | |
| Centre Hospitalier Universitaire de Toulouse | Toulouse cedex 9 | Midi-pyrenees | France | Details | ||
| Hôpital Hôtel-Dieu | Nantes cedex 1 | PAYS DE LA Loire | France | Details | ||
| Institut Paoli Calmettes | Marseille Cedex 9 | Provence Alpes COTE D'azur | France | Details | ||
| Centre Antoine Lacassagne | Nice | Provence Alpes COTE D'azur | France | Details | ||
| Centre Hospitalier Universitaire Grenoble | La Tronche | Rhone-alpes | 38700 | France | Details | |
| Centre Léon Bérard | Lyon Cedex 08 | Rhone-alpes | France | Details | ||
| Centre Hospitalier Lyon Sud | Pierre Bénite Cedex | Rhone-alpes | France | Details | ||
| Universitaetsklinikum Freiburg | Freiburg | Baden-wuerttemberg | Germany | Details | ||
| Universitätsklinikum Ulm | Ulm | Baden-wuerttemberg | Germany | Details | ||
| Schwarzwald-Baar Klinikum Villingen-Schwenningen GmbH | Villingen-Schwenningen | Baden-wuerttemberg | Germany | Details | ||
| Universitätsklinikum Frankfurt Goethe Universität | Frankfurt am Main | Hessen | Germany | Details | ||
| Städtisches Klinikum Braunschweig gGmbH | Braunschweig | Niedersachsen | 38114 | Germany | Details | |
| Marien Hospital Düsseldorf GmbH | Düsseldorf | Nordrhein-westfalen | Germany | Details | ||
| Universitätsklinikum Schleswig-Holstein | Kiel | Schleswig-holstein | Germany | Details | ||
| Bacs-Kiskun Megyei Korhaz | Kecskemét | Bacs-kiskun | Hungary | Details | ||
| Semmelweis Egyetem | Budapest | 1085 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Kozpont | Debrecen | 4032 | Hungary | Details | ||
| Somogy Megyei Kaposi Mór Oktató Kórház | Kaposvár | 7400 | Hungary | Details | ||
| Azienda Ospedaliera Ospedali Riuniti Marche Nord | Pesaro | Pesaro E Urbino | Italy | Details | ||
| IRCCS Centro di Riferimento Oncologico di Basilicata di Rionero in Vulture | Rionero in Vulture | Potenza | Italy | Details | ||
| Azienda Ospedaliero-Univesitaria San Luigi Gonzaga | Orbassano | Torino | Italy | Details | ||
| Azienda Ospedaliera SS. Antonio E. Biagio E. Cesare Arrigo di Alessandria | Alessandria | Italy | Details | |||
| Azienda Ospedaliero-Universitaria di Bologna - Policlinico S.Orsola-Malpighi | Bologna | Italy | Details | |||
| Azienda Ospedaliera Ospedale di Busto Arsizio | Busto Arsizio | 21052 | Italy | Details | ||
| Azienda Ospedaliera-Universitaria Vittorio Emanuele-Ferrarotto-Santo Bambino | Catania | Italy | Details | |||
| IRCCS Azienda Ospedaliera Universitaria San Martino - IST | Genova | Italy | Details | |||
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico | Milano | Italy | Details | |||
| Azienda Ospedaliero-Universitaria Policlinico di Modena | Modena | Italy | Details | |||
| AORN A. Cardarelli | Napoli | Italy | Details | |||
| Azienda Policlinico Umberto I di Roma | Roma | Italy | Details | |||
| Azienda Ospedaliero Universitaria S. Maria della Misericordia di Udine | Udine | Italy | Details | |||
| Chubu | Japan | Details | ||||
| Chugoku | Japan | Details | ||||
| Kanto | Japan | Details | ||||
| Kinki | Japan | Details | ||||
| Kyushu | Japan | Details | ||||
| Tohoku | Japan | Details | ||||
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | Korea, Republic of | Details | ||
| Chonnam National University Hwasun Hospital | Hwasun | Jeollanam-do | Korea, Republic of | Details | ||
| Seoul National University Hospital | Jongno Gu | Seoul | Korea, Republic of | Details | ||
| Inje University Busan Paik Hospital | Busan | Korea, Republic of | Details | |||
| Kyungpook National University Hospital | Daegu | Korea, Republic of | Details | |||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Samsung Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul Saint Mary's Hospital | Seoul | Korea, Republic of | Details | |||
| Severance Hospital, Yonsei University Health System | Seoul | Korea, Republic of | Details | |||
| Ulsan University Hospital | Ulsan | Korea, Republic of | Details | |||
| Universitair Medisch Centrum Utrecht | Utrecht | Netherlands | Details | |||
| Samodzielny Publiczny Szpital Kliniczny Nr 1 we Wroclawiu | Wroclaw | Dolnoslaskie | Poland | Details | ||
| Wojewodzki Szpital Specjalistyczny im. M. Kopernika | Lódz | Lodzkie | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie | Lublin | Lubelskie | Poland | Details | ||
| Instytut Hematologii i Transfuzjologii | Warszawa | Mazowieckie | Poland | Details | ||
| Samodzielny Publiczny Centralny Szpital Kliniczny | Warszawa | Mazowieckie | Poland | Details | ||
| Szpital Wojewódzki w Opolu - Samodzielny Publiczny Zaklad Opieki Zdrowotnej | Opole | Opolskie | Poland | Details | ||
| Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespól Szpitali Miejskich | Chorzów | Slaskie | Poland | Details | ||
| Spitalul Clinic Judetean de Urgenta Tirgu-Mures | Targu-Mures | Mures | Romania | Details | ||
| Institutul Regional de Oncologie Iasi | Iasi | Romania | Details | |||
| Sverdlovsk Regional Clinical Hospital #1 | Ekaterinburg | Russian Federation | Details | |||
| Ryazan Regional Clinical Hospital | Ryazan | Russian Federation | Details | |||
| Saratov State Medical University | Saratov | Russian Federation | Details | |||
| Clinical Center of Serbia | Belgrade | Serbia | Details | |||
| Clinical Centre of Vojvodina | Novi Sad | Serbia | Details | |||
| Hospital Universitario Central de Asturias | Oviedo | Asturias | Spain | Details | ||
| Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona | Spain | Details | ||
| Hospital Vall d´Hebrón | Barcelona | Spain | Details | |||
| Hospital San Pedro de Alcantara | Caceres | Spain | Details | |||
| Hospital General Virgen de las Nieves | Granada | Spain | Details | |||
| Hospital General Universitario Gregorio Marañon | Madrid | Spain | Details | |||
| Hospital Universitario 12 de Octubre | Madrid | Spain | Details | |||
| Hospital Clínico Universitario de Salamanca | Salamanca | Spain | Details | |||
| Hospital Universitario Virgen del Rocio | Sevilla | Spain | Details | |||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | 46026 | Spain | Details | ||
| Skånes Universitetssjukhus i Lund | Lund | Skane | Sweden | Details | ||
| Karolinska University Hospital Huddinge | Stockholm | Sweden | Details | |||
| Chang Gung Medical Foundation-LinKou Branch | Tao-Yuan | Taoyuan | Taiwan | Details | ||
| China Medical University Hospital | Taichung | Taiwan | Details | |||
| Mackay Memorial Hospital | Taipei | Taiwan | Details | |||
| National Taiwan University Hospital | Taipei | Taiwan | Details | |||
| Taipei Veterans General Hospital | Taipei | Taiwan | Details | |||
| Chelsea and Westminster Hospital NHS Foundation Trust | London | England | United Kingdom | Details | ||
| King's College Hospital | London | England | United Kingdom | Details | ||
| Medway Maritime Hospital | Gillingham | Kent | United Kingdom | Details |