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| NCT ID | NCT02420821 |
| Title | A Study of MPDL3280A (Anti-Programmed Death Ligand 1 [PD-L1] Antibody) in Combination With Bevacizumab Versus Sunitinib in Patients With Untreated Advanced Renal Cell Carcinoma |
| Acronym | IMmotion151 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | TUR | POL | ITA | GBR | FRA | ESP | DNK | DEU | CZE | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | United States | Details | |
| University of California at Irvine Medical Center; Department of Oncology | Orange | California | 92868 | United States | Details | |
| University of California | San Francisco | California | 94158 | United States | Details | |
| University of Colorado; Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | United States | Details | |
| Rocky Mountain Cancer Center; Medical Oncology | Boulder | Colorado | 80303 | United States | Details | |
| Georgetown U; Lombardi Comp Can | Washington | District of Columbia | 20016-1468 | United States | Details | |
| Lynn Cancer Institute/Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | United States | Details | |
| Florida Cancer Specialists - Port Charlotte | Port Charlotte | Florida | 33980 | United States | Details | |
| Florida Cancer Specialist, North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Piedmont Cancer Institute, PC | Atlanta | Georgia | 30318 | United States | Details | |
| The University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Dana Farber Cancer Inst. | Boston | Massachusetts | 02115 | United States | Details | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
| Comprehensive Cancer Centers of Nevada - Eastern Avenue | Las Vegas | Nevada | 89169 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| New York Oncology Hematology,P.C.-Albany | Albany | New York | 12208 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | United States | Details | |
| Cleveland Clinic Foundation; Taussig Cancer Center | Cleveland | Ohio | 44195 | United States | Details | |
| Northwest Cancer Specialists, P.C. | Tigard | Oregon | 97223 | United States | Details | |
| SCRI Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | United States | Details | |
| Sarah Cannon Cancer Center and Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Vanderbilt Univ Medical Ctr | Nashville | Tennessee | 37232 | United States | Details | |
| Texas Oncology-Baylor Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
| Oncology and Hematology Associates of SW Virginia-Raonoke | Roanoke | Virginia | 24014 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| Lifehouse | Camperdown | New South Wales | 2050 | Australia | Details | |
| Macquarie University Hospital | Macquarie Park | New South Wales | 2109 | Australia | Details | |
| Calvary Mater Newcastle; Medical Oncology | Waratah | New South Wales | 2298 | Australia | Details | |
| Icon Cancer Foundation | South Brisbane | Queensland | 4101 | Australia | Details | |
| Ashford Cancer Center Research | Kurralta Park | South Australia | 5037 | Australia | Details | |
| Austin Hospital; Medical Oncology | Heidelberg | Victoria | 3084 | Australia | Details | |
| St John of God Hospital | Murdoch | Western Australia | 6150 | Australia | Details | |
| University Clinical Centre of the Republic of Srpska | Banja Luka | 78000 | Bosnia and Herzegovina | Details | ||
| Hospital de Caridade de Ijui; Oncologia | Ijui | RS | 98700-000 | Brazil | Details | |
| Santa Casa de Misericordia de Porto Alegre | Porto Alegre | RS | 90050-170 | Brazil | Details | |
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Sao Paulo | SP | 01246-000 | Brazil | Details | |
| Queen Elizabeth II Health Sciences Centre; Oncology | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details | |
| Royal Victoria Hospital | Barrie | Ontario | L4M 6M2 | Canada | Details | |
| Hamilton Health Sciences - Juravinski Cancer Centre | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| London Regional Cancer Centre | London | Ontario | N6A 4L6 | Canada | Details | |
| Lakeridge Health Oshawa; Oncology | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| The Ottawa Hospital Cancer Centre; Oncology | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Cancer Center | Toronto | Ontario | M5G 1Z5 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| CHU de Quebec Hotel-Dieu de Quebec | Quebec City | Quebec | G1R 2J6 | Canada | Details | |
| Masarykuv onkologicky ustav | Brno | 656 53 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika | Praha 2 | 128 08 | Czechia | Details | ||
| Thomayerova nemocnice | Praha 4 - Krc | 140 59 | Czechia | Details | ||
| Aarhus Universitetshospital; Kræftafdelingen | Aarhus N | 8200 | Denmark | Details | ||
| Herlev Hospital; Afdeling for Kræftbehandling | Herlev | 2730 | Denmark | Details | ||
| Odense Universitetshospital, Onkologisk Afdeling R | Odense C | 5000 | Denmark | Details | ||
| ICO Paul Papin; Oncologie Medicale. | Angers | 49055 | France | Details | ||
| Hopital Saint Andre; Oncologie 2 | Bordeaux | 33075 | France | Details | ||
| Centre Francois Baclesse; Urologie Gynecologie | Caen | 14076 | France | Details | ||
| Centre Oscar Lambret | Lille | 59020 | France | Details | ||
| Centre Léon Bérard | Lyon | 69373 | France | Details | ||
| Institut Paoli Calmettes; Oncologie Medicale | Marseille | 13273 | France | Details | ||
| Centre D'Oncologie de Gentilly; Oncology | Nancy | 54100 | France | Details | ||
| APHP - Hospital Saint Louis | Paris | 75475 | France | Details | ||
| Hopital Europeen Georges Pompidou; Service D'Oncologie Medicale | Paris | 75908 | France | Details | ||
| ICO - Site René Gauducheau | Saint Herblain | 44805 | France | Details | ||
| Institut Gustave Roussy; Departement Oncologie Medicale | Villejuif | 94805 | France | Details | ||
| Universitätsklinikum "Carl Gustav Carus"; Klinik und Poliklinik für Urologie | Dresden | 01307 | Germany | Details | ||
| Universitätsklinikum Essen; Innere Klinik und Poliklinik für Tumorforschung | Essen | 45122 | Germany | Details | ||
| Nationales Centrum für Tumorerkrankungen Heidelberg (NCT); Thoraxklinik Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| Klinikum d.Universität München Campus Großhadern | München | 81377 | Germany | Details | ||
| Universitätsklinikum Tübingen; Klinik für Urologie | Tübingen | 72076 | Germany | Details | ||
| Az. Osp. Cardarelli; Divisione Di Oncologia | Napoli | Campania | 80131 | Italy | Details | |
| IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica | Meldola | Emilia-Romagna | 47014 | Italy | Details | |
| A.O. Universitaria Policlinico Di Modena; Oncologia | Modena | Emilia-Romagna | 41100 | Italy | Details | |
| Azienda Ospedaliera San Camillo Forlanini; Oncologia Medica | Roma | Lazio | 00152 | Italy | Details | |
| Irccs Ospedale San Raffaele;Oncologia Medica | Milano | Lombardia | 20132 | Italy | Details | |
| Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia | Milano | Lombardia | 20162 | Italy | Details | |
| Fondazione IRCCS Policlinico San Matteo, Oncologia | Pavia | Lombardia | 27100 | Italy | Details | |
| Azienda USL8 Arezzo-Presidio Ospedaliero 1 San Donato;U.O.C. Oncologia | Arezzo | Toscana | 52100 | Italy | Details | |
| Nagoya University Hospital; Urology | Aichi | 466-8560 | Japan | Details | ||
| Chiba Cancer Center | Chiba | 260-8717 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| Gunma University Hospital | Gunma | 371-8511 | Japan | Details | ||
| Hokkaido University Hospital | Hokkaido | 060-8648 | Japan | Details | ||
| University of Tsukuba Hospital; Urology | Ibaraki | 305-8576 | Japan | Details | ||
| Iwate Medical University Hospital | Iwate | 028-3695 | Japan | Details | ||
| Yokohama City University Hospital | Kanagawa | 236-0004 | Japan | Details | ||
| Kitasato University Hospital | Kanagawa | 252-0375 | Japan | Details | ||
| Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
| Niigata University Medical & Dental Hospital | Niigata | 951-8520 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| Osaka International Cancer Institute; Urology | Osaka | 541-8567 | Japan | Details | ||
| Osaka Metropolitan University Hospital | Osaka | 545-8586 | Japan | Details | ||
| Osaka University Hospital | Osaka | 565-0871 | Japan | Details | ||
| Kindai University Hospital | Osaka | 589-8511 | Japan | Details | ||
| Tokushima University Hospital | Tokushima | 770-8503 | Japan | Details | ||
| Toranomon Hospital | Tokyo | 105-8470 | Japan | Details | ||
| Tokyo Medical and Dental University Hospital | Tokyo | 113-8519 | Japan | Details | ||
| Nippon Medical School Hospital | Tokyo | 113-8603 | Japan | Details | ||
| The Cancer Institute Hospital, JFCR; Urology | Tokyo | 135-8550 | Japan | Details | ||
| Keio University Hospital | Tokyo | 160-8582 | Japan | Details | ||
| Tokyo Women's Medical University | Tokyo | 162-0054 | Japan | Details | ||
| Chungnam National University Hospital | Daejeon | 35015 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 003-722 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| Cancerología | Queretaro | 76090 | Mexico | Details | ||
| Centro Oncologico Estatal ISSEMYM | Toluca | 50180 | Mexico | Details | ||
| Centrum Onkologii Ziemi Lubelskiej im. św. Jana z Dukli | Lublin | 20-090 | Poland | Details | ||
| Szpital Kliniczny; Przemienienia Panskiego;Uniwersytetu Medyczny im.; Karola Marcinkowskiego w Pozna | Poznan | 60-569 | Poland | Details | ||
| Saint Elizabeth's Hospital | Warsaw | 02-616 | Poland | Details | ||
| MAGODENT Sp. z o.o. | Warsaw | 04-125 | Poland | Details | ||
| ALTAI REGIONAL ONCOLOGICAL CENTER; "Nadezhda" Clinic | Barnaul | Altaj | 656049 | Russian Federation | Details | |
| GBUZ Nizhegorodskay Region: Clinical Diagnostic Center | Nizhni Novgorod | Niznij Novgorod | 603001 | Russian Federation | Details | |
| P.A. Herzen Oncological Inst. ; Oncology | Moscow | 125284 | Russian Federation | Details | ||
| City Clinical Oncology Hospital | Moscow | 143423 | Russian Federation | Details | ||
| National University Hospital | Singapore | 117599 | Singapore | Details | ||
| National Cancer Centre; Medical Oncology | Singapore | 169610 | Singapore | Details | ||
| Corporacio Sanitaria Parc Tauli; Servicio de Oncologia | Sabadell | Barcelona | 8208 | Spain | Details | |
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic i Provincial; Servicio de Oncología | Barcelona | 08036 | Spain | Details | ||
| Hospital Duran i Reynals; Oncologia | Barcelona | 08907 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | Madrid | 28007 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Taichung Veterans General Hospital; Division of Urology | Taichung | 407 | Taiwan | Details | ||
| National Taiwan Uni Hospital; Dept of Oncology | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Medical Foundation-Linkou, Urinary Oncology | Taoyuan | 333 | Taiwan | Details | ||
| Chulalongkorn Hospital; Medical Oncology | Bangkok | 10330 | Thailand | Details | ||
| Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc | Bangkok | 10400 | Thailand | Details | ||
| Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology | Bangkok | 10700 | Thailand | Details | ||
| Maharaj Nakorn Chiangmai Hospital; Department of Surgery/ Urology unit | Chiangmai | 50200 | Thailand | Details | ||
| Songklanagarind Hospital; Department of Oncology | Songkhla | 90110 | Thailand | Details | ||
| Hacettepe University Medical Faculty | Ankara | 06100 | Turkey | Details | ||
| Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department | Edirne | 22770 | Turkey | Details | ||
| Istanbul Uni Cerrahpasa Medical Faculty Hospital; Medical Oncology | Istanbul | 34300 | Turkey | Details | ||
| Clatterbridge Cancer Centre | Bebington | CH63 4JY | United Kingdom | Details | ||
| Queen Elizabeth Hospital | Birmingham | B15 2TH | United Kingdom | Details | ||
| Royal Blackburn Hospital | Blackburn | BB2 3HH | United Kingdom | Details | ||
| Addenbrookes Nhs Trust; Oncology Clinical Trials Unit | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Barts Health NHS Trust - St Bartholomew's Hospital | London | EC1A 7BE | United Kingdom | Details | ||
| Royal Free Hospital; Dept of Oncology | London | NW3 2QG | United Kingdom | Details | ||
| Christie Hospital Nhs Trust; Medical Oncology | Manchester | M2O 4BX | United Kingdom | Details | ||
| Churchill Hospital; Oxford Cancer and Haematology Centre | Oxford | OX3 7LJ | United Kingdom | Details | ||
| Southampton General Hospital; Medical Oncology | Southampton | SO16 6YD | United Kingdom | Details | ||
| Royal Marsden Hospital; Dept of Medical Oncology | Sutton | SM2 5PT | United Kingdom | Details | ||
| Singleton Hospital; Pharmacy Department | Swansea | SA2 8QA | United Kingdom | Details |