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| NCT ID | NCT02437318 |
| Title | Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment. (SOLAR-1) |
| Acronym | SOLAR-1 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | SWE | ROU | NLD | LBN | ITA | ISR | HUN | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BGR | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ironwood Cancer and Research Centers Chandler 2 | Chandler | Arizona | 85224 | United States | Details | |
| Mayo Clinic - Arizona | Scottsdale | Arizona | 85259 | United States | Details | |
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | United States | Details | |
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010 3000 | United States | Details | |
| Scripps Clinic SC | La Jolla | California | 92037 | United States | Details | |
| Kaiser Permanente - California Southern | San Diego | California | 92120 | United States | Details | |
| University of California San Francisco | San Francisco | California | 94115 | United States | Details | |
| Florida Cancer Specialists FL Cancer Specialists | Fort Myers | Florida | 33901 | United States | Details | |
| Florida Cancer Specialists-North SC | Saint Petersburg | Florida | 33705 | United States | Details | |
| Rush University Medical Center Rush Uni Medical Center | Chicago | Illinois | 60612 | United States | Details | |
| NorthShore University Health System NorthShore University | Evanston | Illinois | 60201 | United States | Details | |
| Edward Cancer Center SC | Naperville | Illinois | 60540 | United States | Details | |
| Fort Wayne Medical Oncology/Hematology, Inc. Dept.of Fort Wayne Med Onc/Hem | Fort Wayne | Indiana | 46815 | United States | Details | |
| St. Francis Health Comprehensive Cancer Center SC | Topeka | Kansas | 66606-169 | United States | Details | |
| Mercy Medical Center SC-2 | Baltimore | Maryland | 21202 | United States | Details | |
| Massachusetts General Hospital Updated Regulatory | Boston | Massachusetts | 02114 | United States | Details | |
| Lahey Clinic | Burlington | Massachusetts | 01805 | United States | Details | |
| Detroit Clinical Research Center | Owosso | Michigan | 48867 | United States | Details | |
| St. Luke's Cancer Institute SC | Kansas City | Missouri | 64111 | United States | Details | |
| St Vincent Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
| Rutgers Cancer Institute of New Jersey SC-2 | New Brunswick | New Jersey | 08903 | United States | Details | |
| University Hospitals of Cleveland Seidman Cancer Center SC | Cleveland | Ohio | 44106 | United States | Details | |
| Good Samaritan Regional Medical Center Good Samaritan Reg Med Ctr | Corvallis | Oregon | 97330 | United States | Details | |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | United States | Details | |
| Prisma Health Upstate SC-2 | Greenville | South Carolina | 29615 | United States | Details | |
| Avera Cancer SC | Sioux Falls | South Dakota | 57105 | United States | Details | |
| Tennessee Oncology SC-3 | Nashville | Tennessee | 37203 | United States | Details | |
| Texas Oncology PA Dallas Presbyterian Hospital SC-1 | Dallas | Texas | 75231 | United States | Details | |
| El Paso, Texas Oncology | El Paso | Texas | 79902 | United States | Details | |
| Mays Cancer Ctr Uthsa Mdacc InstituteForDrugDevelopment(4) | San Antonio | Texas | 78229 | United States | Details | |
| Texas Oncology Northeast Texas | Tyler | Texas | 75702 | United States | Details | |
| Virginia Cancer Specialists SC | Fairfax | Virginia | 22031 | United States | Details | |
| Wenatchee Valley Medical Center SC-2 | Wenatchee | Washington | 98801 | United States | Details | |
| Novartis Investigative Site | Berazategui | Buenos Aires | B1884BBF | Argentina | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1125ABD | Argentina | Details | |
| Novartis Investigative Site | Rio Negro | Viedma | 8500 | Argentina | Details | |
| Novartis Investigative Site | La Rioja | 5300 | Argentina | Details | ||
| Novartis Investigative Site | Wahroonga | New South Wales | 2076 | Australia | Details | |
| Novartis Investigative Site | Wooloongabba | Queensland | 4102 | Australia | Details | |
| Novartis Investigative Site | Elizabeth Vale | South Australia | 5112 | Australia | Details | |
| Novartis Investigative Site | Melbourne | Victoria | 3000 | Australia | Details | |
| Novartis Investigative Site | Linz | 4010 | Austria | Details | ||
| Novartis Investigative Site | Vienna | 1090 | Austria | Details | ||
| Novartis Investigative Site | Edegem | Antwerpen | 2650 | Belgium | Details | |
| Novartis Investigative Site | Jette | Brussel | 1090 | Belgium | Details | |
| Novartis Investigative Site | Sint Niklaas | Oost Vlaanderen | 9100 | Belgium | Details | |
| Novartis Investigative Site | Bruxelles | 1000 | Belgium | Details | ||
| Novartis Investigative Site | Libramont | 6800 | Belgium | Details | ||
| Novartis Investigative Site | Ottignies | 1340 | Belgium | Details | ||
| Novartis Investigative Site | Verviers | 4800 | Belgium | Details | ||
| Novartis Investigative Site | Natal | RN | 59075 740 | Brazil | Details | |
| Novartis Investigative Site | Lajeado | RS | 95900-000 | Brazil | Details | |
| Novartis Investigative Site | Sao Paulo | SP | 04014-002 | Brazil | Details | |
| Novartis Investigative Site | Sao Jose do Rio Preto | 15090 000 | Brazil | Details | ||
| Novartis Investigative Site | Sao Paulo | 01236 030 | Brazil | Details | ||
| Novartis Investigative Site | Plovdiv | 4004 | Bulgaria | Details | ||
| Novartis Investigative Site | Sofia | 1756 | Bulgaria | Details | ||
| Novartis Investigative Site | Varna | 9002 | Bulgaria | Details | ||
| Novartis Investigative Site | Varna | 9010 | Bulgaria | Details | ||
| Novartis Investigative Site | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Novartis Investigative Site | Cambridge | Ontario | N1R 3G2 | Canada | Details | |
| Novartis Investigative Site | Ottawa | Ontario | KIH 7W9 | Canada | Details | |
| Novartis Investigative Site | Toronto | Ontario | M5B 1W8 | Canada | Details | |
| Novartis Investigative Site | Quebec | G1S 4L8 | Canada | Details | ||
| Novartis Investigative Site | Temuco | Araucania | 4810469 | Chile | Details | |
| Novartis Investigative Site | Santiago | 8420383 | Chile | Details | ||
| Novartis Investigative Site | Vina del Mar | 2520612 | Chile | Details | ||
| Novartis Investigative Site | Hradec Kralove | Czech Republic | 500 05 | Czechia | Details | |
| Novartis Investigative Site | Praha 4 | Czech Republic | 140 46 | Czechia | Details | |
| Novartis Investigative Site | Zlin | Czech Republic | 762 75 | Czechia | Details | |
| Novartis Investigative Site | Prague 8 | 180 00 | Czechia | Details | ||
| Novartis Investigative Site | Marseille cedex 20 | Bouches Du Rhone | 13915 | France | Details | |
| Novartis Investigative Site | Angers 02 | 49055 | France | Details | ||
| Novartis Investigative Site | Avignon | 84082 | France | Details | ||
| Novartis Investigative Site | Caen | 14021 | France | Details | ||
| Novartis Investigative Site | Clermont Ferrand | 63011 | France | Details | ||
| Novartis Investigative Site | Creteil | 94010 | France | Details | ||
| Novartis Investigative Site | La Roche sur Yon cedex 9 | 85925 | France | Details | ||
| Novartis Investigative Site | Le Chesnay | 78157 | France | Details | ||
| Novartis Investigative Site | Levallois-Perret | 92309 | France | Details | ||
| Novartis Investigative Site | Lyon Cedex 08 | 69373 | France | Details | ||
| Novartis Investigative Site | Montpellier | 34070 | France | Details | ||
| Novartis Investigative Site | Nimes | 30029 | France | Details | ||
| Novartis Investigative Site | Rouen | 76038 | France | Details | ||
| Novartis Investigative Site | Saint-Herblain Cédex | 44805 | France | Details | ||
| Novartis Investigative Site | Toulouse | 31059 | France | Details | ||
| Novartis Investigative Site | Villejuif Cedex | 94800 | France | Details | ||
| Novartis Investigative Site | Recklinghausen | North Rhine-westphalia | 45657 | Germany | Details | |
| Novartis Investigative Site | Leipzig | Sachsen | 04277 | Germany | Details | |
| Novartis Investigative Site | Luebeck | Schleswig-Holstein | 23563 | Germany | Details | |
| Novartis Investigative Site | Aschaffenburg | 63739 | Germany | Details | ||
| Novartis Investigative Site | Frankfurt | 60389 | Germany | Details | ||
| Novartis Investigative Site | Friedrichshafen | 88045 | Germany | Details | ||
| Novartis Investigative Site | Hannover | 30625 | Germany | Details | ||
| Novartis Investigative Site | Homburg | 66421 | Germany | Details | ||
| Novartis Investigative Site | Kiel | 24105 | Germany | Details | ||
| Novartis Investigative Site | Mainz | 55131 | Germany | Details | ||
| Novartis Investigative Site | Potsdam | 14467 | Germany | Details | ||
| Novartis Investigative Site | Rostock | 18059 | Germany | Details | ||
| Novartis Investigative Site | Ulm | 89081 | Germany | Details | ||
| Novartis Investigative Site | Velbert | 42551 | Germany | Details | ||
| Novartis Investigative Site | Thessaloniki | GR | 564 29 | Greece | Details | |
| Novartis Investigative Site | Athens | 115 28 | Greece | Details | ||
| Novartis Investigative Site | Athens | 18547 | Greece | Details | ||
| Novartis Investigative Site | Hong Kong | Hong Kong | Details | |||
| Novartis Investigative Site | Budapest | 1134 | Hungary | Details | ||
| Novartis Investigative Site | Budapest | H 1122 | Hungary | Details | ||
| Novartis Investigative Site | Nyiregyhaza | 4400 | Hungary | Details | ||
| Novartis Investigative Site | Szekszard | 7100 | Hungary | Details | ||
| Novartis Investigative Site | Vijayawada | Andhra Pradesh | 520002 | India | Details | |
| Novartis Investigative Site | Nagpur - Maharashtra | Maharashtra | 440010 | India | Details | |
| Novartis Investigative Site | Mumbai | 400 012 | India | Details | ||
| Novartis Investigative Site | Beer-Sheva | 8457108 | Israel | Details | ||
| Novartis Investigative Site | Haifa | 3109601 | Israel | Details | ||
| Novartis Investigative Site | Petach Tikva | 4941492 | Israel | Details | ||
| Novartis Investigative Site | Ramat Gan | 52621 | Israel | Details | ||
| Novartis Investigative Site | Tel Aviv | 6423906 | Israel | Details | ||
| Novartis Investigative Site | Ancona | AN | 60126 | Italy | Details | |
| Novartis Investigative Site | Chieti | CH | 66100 | Italy | Details | |
| Novartis Investigative Site | Meldola | FC | 47014 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20133 | Italy | Details | |
| Novartis Investigative Site | Palermo | PA | 90127 | Italy | Details | |
| Novartis Investigative Site | Padova | PD | 35100 | Italy | Details | |
| Novartis Investigative Site | Pontedera | PI | 56025 | Italy | Details | |
| Novartis Investigative Site | Aviano | PN | 33081 | Italy | Details | |
| Novartis Investigative Site | Rionero in Vulture | PZ | 85028 | Italy | Details | |
| Novartis Investigative Site | Roma | RM | 00155 | Italy | Details | |
| Novartis Investigative Site | Sassari | SS | 07100 | Italy | Details | |
| Novartis Investigative Site | Savona | SV | 17100 | Italy | Details | |
| Novartis Investigative Site | Torino | TO | 10126 | Italy | Details | |
| Novartis Investigative Site | Negrar | VR | 37024 | Italy | Details | |
| Novartis Investigative Site | Nagoya | Aichi | 464 8681 | Japan | Details | |
| Novartis Investigative Site | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Novartis Investigative Site | Maebashi city | Gunma | 371 8511 | Japan | Details | |
| Novartis Investigative Site | Sapporo-city | Hokkaido | 003-0804 | Japan | Details | |
| Novartis Investigative Site | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Novartis Investigative Site | Kagoshima-city | Kagoshima | 892-0833 | Japan | Details | |
| Novartis Investigative Site | Isehara | Kanagawa | 259-1193 | Japan | Details | |
| Novartis Investigative Site | Yokohama-city | Kanagawa | 241-8515 | Japan | Details | |
| Novartis Investigative Site | Kumamoto City | Kumamoto | 860-8556 | Japan | Details | |
| Novartis Investigative Site | Osaka-city | Osaka | 540-0006 | Japan | Details | |
| Novartis Investigative Site | Osaka-city | Osaka | 541-8567 | Japan | Details | |
| Novartis Investigative Site | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Novartis Investigative Site | Chuo ku | Tokyo | 104-8560 | Japan | Details | |
| Novartis Investigative Site | Minato ku | Tokyo | 105-8470 | Japan | Details | |
| Novartis Investigative Site | Bundang Gu | Gyeonggi Do | 13620 | Korea, Republic of | Details | |
| Novartis Investigative Site | Gyeonggi do | Korea | 10408 | Korea, Republic of | Details | |
| Novartis Investigative Site | Seoul | Korea | 05505 | Korea, Republic of | Details | |
| Novartis Investigative Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 03722 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Novartis Investigative Site | Ashrafieh | 166830 | Lebanon | Details | ||
| Novartis Investigative Site | Beirut | 10999 | Lebanon | Details | ||
| Novartis Investigative Site | Saida | 652 | Lebanon | Details | ||
| Novartis Investigative Site | Monterrey NL | Monterrey | 64320 | Mexico | Details | |
| Novartis Investigative Site | San Luis Potosi | 78200 | Mexico | Details | ||
| Novartis Investigative Site | Venray | CE | 5801 | Netherlands | Details | |
| Novartis Investigative Site | Terneuzen | 4535 PA | Netherlands | Details | ||
| Novartis Investigative Site | San Borja | Lima | 41 | Peru | Details | |
| Novartis Investigative Site | Surquillo | Lima | 34 | Peru | Details | |
| Novartis Investigative Site | Lima | LIMA 27 | Peru | Details | ||
| Novartis Investigative Site | Floresti | Cluj | 407280 | Romania | Details | |
| Novartis Investigative Site | Craiova | Dolj | 200347 | Romania | Details | |
| Novartis Investigative Site | Iasi | 700483 | Romania | Details | ||
| Novartis Investigative Site | Arkhangelsk | 163045 | Russian Federation | Details | ||
| Novartis Investigative Site | Ryazan | 390011 | Russian Federation | Details | ||
| Novartis Investigative Site | St Petersburg | 197758 | Russian Federation | Details | ||
| Novartis Investigative Site | Sevilla | Andalucia | 41013 | Spain | Details | |
| Novartis Investigative Site | Jerez | Cadiz | 11407 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Cataluna | 08024 | Spain | Details | |
| Novartis Investigative Site | Badalona | Catalunya | 08916 | Spain | Details | |
| Novartis Investigative Site | Alicante | Comunidad Valenciana | 03010 | Spain | Details | |
| Novartis Investigative Site | Castellon | Comunidad Valenciana | 12002 | Spain | Details | |
| Novartis Investigative Site | Valencia | Comunidad Valenciana | 46010 | Spain | Details | |
| Novartis Investigative Site | Badajoz | Extremadura | 06080 | Spain | Details | |
| Novartis Investigative Site | Caceres | Extremadura | 10003 | Spain | Details | |
| Novartis Investigative Site | Santiago de Compostela | Galicia | 15706 | Spain | Details | |
| Novartis Investigative Site | Palma De Mallorca | Islas Baleares | 07120 | Spain | Details | |
| Novartis Investigative Site | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
| Novartis Investigative Site | El Palmar | Murcia | 30120 | Spain | Details | |
| Novartis Investigative Site | La Laguna | Santa Cruz De Tenerife | 38320 | Spain | Details | |
| Novartis Investigative Site | Madrid | 28034 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28040 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28041 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28046 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28050 | Spain | Details | ||
| Novartis Investigative Site | Gavle | SE-801 87 | Sweden | Details | ||
| Novartis Investigative Site | Oerebro | 70185 | Sweden | Details | ||
| Novartis Investigative Site | Vasteras | 721 89 | Sweden | Details | ||
| Novartis Investigative Site | Taipei | 10002 | Taiwan | Details | ||
| Novartis Investigative Site | Taipei | 11217 | Taiwan | Details | ||
| Novartis Investigative Site | Bangkok | THA | 10330 | Thailand | Details | |
| Novartis Investigative Site | Bangkok | 10700 | Thailand | Details | ||
| Novartis Investigative Site | Plymouth | Devon | PL6 8DH | United Kingdom | Details | |
| Novartis Investigative Site | Leicester | LE1 5WW | United Kingdom | Details | ||
| Novartis Investigative Site | London | SE1 9RT | United Kingdom | Details |