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| NCT ID | NCT02610777 |
| Title | An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Millennium Pharmaceuticals, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | NLD | ITA | ISR | IRL | FRA | ESP | DEU | CZE | CAN | BGR | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | United States | Details | |
| Greenville Health System | Little Rock | Arkansas | 72201 | United States | Details | |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | United States | Details | |
| Compassionate Cancer Care Medical Group Incorporated | Riverside | California | 92501 | United States | Details | |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | United States | Details | |
| Smilow Cancer Center at Yale New Haven Hospital | New Haven | Connecticut | 06510 | United States | Details | |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | United States | Details | |
| H Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | United States | Details | |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Johns Hopkins University | Baltimore | Maryland | 21287 | United States | Details | |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | United States | Details | |
| Monter Cancer Center | Lake Success | New York | 11042 | United States | Details | |
| Weill Cornell Medical College | New York | New York | 10021 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| University of Rochester Medical Center | Rochester | New York | 14603 | United States | Details | |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Cancer Care Center of South Texas | New Braunfels | Texas | 78130 | United States | Details | |
| Nebraska Cancer Specialists | The Woodlands | Texas | 77380 | United States | Details | |
| Texas Oncology - Waco, TX | Tyler | Texas | 76712 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22903 | United States | Details | |
| Medical Oncology Associates | Spokane | Washington | 99208 | United States | Details | |
| Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | United States | Details | |
| AZ Sint-Jan AV | Brugge | West-Vlaanderen | 8400 | Belgium | Details | |
| Grand Hopital de Charleroi asbl | Charleroi | 6000 | Belgium | Details | ||
| Cliniques Universitaires UCL de Mont-Godinne | Yvoir | 5500 | Belgium | Details | ||
| University Multiprofile Hospital for Active Treatment Sv Ivan Rilski EAD | Sofia | 1113 | Bulgaria | Details | ||
| Specialized Hospital for Active Treatment of Haematological Diseases - Sofia | Sofia | 1756 | Bulgaria | Details | ||
| University Multi-Profile Hospital for Active Treatment Dr Georgi Stranski | Sofia | 1756 | Bulgaria | Details | ||
| Sunnybrook Health Science Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Hospital | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Fakultni Nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
| Fakultni Nemocnice Kralovske Vinohrady | Praha 10 | 10034 | Czechia | Details | ||
| CHU de GRENOBLE | Grenoble | 38700 | France | Details | ||
| CHRU Lille | Lille | 59000 | France | Details | ||
| Hopital Saint Louis | Paris | 75010 | France | Details | ||
| Marien Hospital Akademisches Lehrkrankenhaus | Dusseldorf | 40479 | Germany | Details | ||
| Universitatsklinikum Ulm | Ulm | 89081 | Germany | Details | ||
| Tallaght Hospital | Dublin | 24 | Ireland | Details | ||
| University Hospital Galway | Galway | Ireland | Details | |||
| Shaare Zedek Medical Center | Jerusalem | 9103102 | Israel | Details | ||
| ZIV Medical Center | Safed | 13100 | Israel | Details | ||
| Tel Aviv Sourasky Medical Center | Tel Aviv | 13100 | Israel | Details | ||
| Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Careggi | Firenze | 50139 | Italy | Details | ||
| Azienda Ospedaliera Bianchi Melacrino Morelli | Reggio Calabria | 89100 | Italy | Details | ||
| Azienda Ospedaliero Universitaria San Giovanni Battista Di Torino | Torino | 10126 | Italy | Details | ||
| Zuyderland Medisch Centrum | Sittard | 6162 BG | Netherlands | Details | ||
| Hospital Universitario Son Espases | Palma de Mallorca | Baleares | 7010 | Spain | Details | |
| Hospital Universitario Quironsalud Madrid | Pozuelo De Alarcon | Madrid | 28223 | Spain | Details | |
| Hospital Universitario Germans Trias i Pujol | Badalona | 8916 | Spain | Details | ||
| ICO I'Hospitalet Hospital Duran i Reynals Instituto Catalan de Oncologia de Hospitalet (ICO) | Barcelona | 08908 | Spain | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 8036 | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Regional Universitario de Malaga - Hospital Universitario Virgen de la Victoria | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | 46026 | Spain | Details |