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| NCT ID | NCT02775903 |
| Title | An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Subjects With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Subjects With Acute Myeloid Leukemia (AML) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Celgene Corporation |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Yale Cancer Center | New Haven | Connecticut | 06520 | United States | Details | |
| Georgetown University Hospital | Washington | District of Columbia | 20007 | United States | Details | |
| University of Florida | Gainesville | Florida | 32610 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27705 | United States | Details | |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37203 | United States | Details | |
| University of Texas- MD Anderson | Houston | Texas | 77230 | United States | Details | |
| Medizinische Universitat Graz | Graz | 8036 | Austria | Details | ||
| Medizinische Universitat Innsbruck | Innsbruck | 6020 | Austria | Details | ||
| Elisabethinen Hospital Linz | Linz | 4020 | Austria | Details | ||
| Salzburger Landkliniken St. Johanns-Spital | Salzburg | 5020 | Austria | Details | ||
| AKH Wien | Wein | 1090 | Austria | Details | ||
| Hanusch Krankenhaus der Stadt Wien | Wien | 1140 | Austria | Details | ||
| Local Institution - 653 | Wien | 1140 | Austria | Details | ||
| Cliniques Universitaires St-Luc | Brussels | 1200 | Belgium | Details | ||
| Grand Hopital de Charleroi | Charleroi | 6000 | Belgium | Details | ||
| Local Institution - 202 | Gent | 9000 | Belgium | Details | ||
| UH Gent | Gent | 9000 | Belgium | Details | ||
| UH Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Cliniques Universitaires UCL de Mont-Godine | Yvoir | 5530 | Belgium | Details | ||
| University of Alberta | Edmonton | Alberta | T6g2b7 | Canada | Details | |
| CancerCare Manitoba | Winnipeg | Manitoba | R3E 0V9 | Canada | Details | |
| Saint John Regional Hospital | Saint John | New Brunswick | E2L 4L2 | Canada | Details | |
| Ottawa General Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| CHUM - Notre Dame | Montreal | Quebec | H2L 4M1 | Canada | Details | |
| Centre Hospitalier Universitaire d' Angers | Angers | 67091 | France | Details | ||
| Hopital Avicenne | Bobigny Cedex | 93009 | France | Details | ||
| Hopital Henri Mondor | Creteil | 94010 | France | Details | ||
| Centre Hospitalier Universitaire de Grenoble Hopital Albert Michallon | La Tronche | 38700 | France | Details | ||
| Centre Leon Berard | Lyon | 69008 | France | Details | ||
| Local Institution - 261 | Lyon | 69008 | France | Details | ||
| CHRU de Nantes - Hotel Dieu | Nantes | 44093 | France | Details | ||
| Hopital Saint Louis | Paris | 75010 | France | Details | ||
| Local Institution - 251 | Paris | 75010 | France | Details | ||
| CHU Bordeaux | Pessac | 33604 | France | Details | ||
| Local Institution - 254 | Pessac | 33604 | France | Details | ||
| Centre Hospitalier Lyon Sud | Pierre-Bénite Cedex | 69495 | France | Details | ||
| IUCT Oncopole | Toulouse | 31059 Cedex 9 | France | Details | ||
| Local Institution - 604 | Dresden | 01307 | Germany | Details | ||
| Universitatsklinikum Carl Gustav Carus | Dresden | 01307 | Germany | Details | ||
| Local Institution - 603 | Dusseldorf | 40479 | Germany | Details | ||
| Marien Hospital | Dusseldorf | 40479 | Germany | Details | ||
| Universitatsklinikum Essen | Essen | 45122 | Germany | Details | ||
| Klinikum der Johann Wolfgang Goethe Universitat | Frankfurt am Main | 60590 | Germany | Details | ||
| Universitatsklinikum Freiburg | Freiburg | 79106 | Germany | Details | ||
| Medizinische Hochschule HannoverZentrum Innere Medizin | Hannover | 30625 | Germany | Details | ||
| Universitatsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| Klinikum der LMU Campus Grosshadern | Munchen | 1307 | Germany | Details | ||
| Local Institution - 605 | Munchen | 1307 | Germany | Details | ||
| Klinikum rechts der Isar der TU Munchen | Munchen | 81675 | Germany | Details | ||
| Universitatsklinikum Ulm | Ulm | 89081 | Germany | Details | ||
| AO Spedali Civili di Brescia | Brecia | 25123 | Italy | Details | ||
| Azienda Ospedaliero-Universitaria Careggi | Firenze | 50134 | Italy | Details | ||
| Ospedale Niguarda Milano | Milano | 20162 | Italy | Details | ||
| Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello | Palermo | 33100 | Italy | Details | ||
| I.R.C.C.S. Policlinico San Matteo - Universita di Pavia | Pavia | 27100 | Italy | Details | ||
| Local Institution - 302 | Pavia | 27100 | Italy | Details | ||
| Azienda Ospedaliera Bianchi-Melacrino-Morelli | Roma | 133 | Italy | Details | ||
| Local Institution - 303 | Roma | 133 | Italy | Details | ||
| Policlinico Agostino Gemelli - Istituto di Ematologia | Roma | 89100 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Policlinico Tor Vergata | Rome | 133 | Italy | Details | ||
| Local Institution - 304 | Rome | 133 | Italy | Details | ||
| Azienda Ospedaliero-Universitaria Santa Maria della Misericordia die Udine | Udine | 30174 | Italy | Details | ||
| Universita degli Studi dell'Insubria - Ospedale di Circolo e Fondazione Macchi - Varese | Varese | 21100 | Italy | Details | ||
| VU University Medical Center | Amsterdam | 1081 HV | Netherlands | Details | ||
| Oddzial Hematologii Onkologicznej Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologicz | Brzozow | 36-200 | Poland | Details | ||
| Katedra i Klinika Hematologii i Transplantologii Uniwersyteckie Centrum Kliniczne | Gdansk | 80-211 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny nr 1 Klinika Hematoonkologii i Transplantacji Szpiku | Lubin | 20-081 | Poland | Details | ||
| Oddzial Hematologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej MSW | Olsztyn | 10-228 | Poland | Details | ||
| Klinika Hematologii Nowotworow Krwi i Transplantacji Szpiku | Wroclaw | 50-367 | Poland | Details | ||
| Hospitais da Universidade de Coimbra | Coimbra | 3000-076 | Portugal | Details | ||
| Instituto Portugues de Oncologia de Lisboa Francisco Gentil EPE | Lisbon | 1099-023 | Portugal | Details | ||
| Ipo Instituto Portugues De Oncologia Porto | Porto | 4200-072 | Portugal | Details | ||
| Local Institution - 502 | Porto | 4200-072 | Portugal | Details | ||
| Hospital de Sao Joao | Porto | 4200 | Portugal | Details | ||
| Hospital Universitario Vall D hebron | Barcelona | 28040 | Spain | Details | ||
| Hospital Clinic I Provincial de Barcelona | Barcelona | 8036 | Spain | Details | ||
| Complejo Hospitalario San Pedro de Alcantara | Caceres | 10003 | Spain | Details | ||
| Hospital Universitario La Princesa | Madrid | 28006 | Spain | Details | ||
| Hospital Gregorio Maranon | Madrid | 37007 | Spain | Details | ||
| Local Institution - 555 | Madrid | 37007 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria | Malaga | 29010 | Spain | Details | ||
| Hospital Son Llatzer | Palma de Mallorca | 7198 | Spain | Details | ||
| Hospital Universitario de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hospital Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitario La Fe | Valencia | 46009 | Spain | Details | ||
| Local Institution - 559 | Valencia | 46009 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| University Hospital Birmingham | Birmingham | B15 2TH | United Kingdom | Details | ||
| St James University Hospital | Leeds | LS1 3EX | United Kingdom | Details | ||
| University College London Hospital | London Bloomsbury | WC1E 6AU | United Kingdom | Details | ||
| St Bartholomews Hospital | London | EC1 7BE | United Kingdom | Details | ||
| Kings College Hospital | London | SE5 9RS | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| John Radcliffe Hospital | Oxford | OX3 9DU | United Kingdom | Details | ||
| Local Institution - 453 | Oxford | OX3 9DU | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | Sutton | SM2 5PT | United Kingdom | Details |