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| NCT ID | NCT02907359 |
| Title | Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Astex Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | POL | ITA | GBR | FRA | ESP | DNK | DEU | CZE | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | United States | Details | |
| Desert Hematology Oncology Medical Group, Inc. | Rancho Mirage | California | 92270 | United States | Details | |
| Cancer Specialists of North Florida | Fleming Island | Florida | 32003 | United States | Details | |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | United States | Details | |
| Rush University Medical Center | Chicago | Illinois | 60612 | United States | Details | |
| North Shore Medical Center | Evanston | Illinois | 60201 | United States | Details | |
| Franciscan Health Indianapolis | Indianapolis | Indiana | 46237 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| University of Michigan Cancer Center | Ann Arbor | Michigan | 48109 | United States | Details | |
| John Theurer Cancer Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Weill Cornell Medical College | New York | New York | 10065 | United States | Details | |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | United States | Details | |
| Duke Cancer Center | Durham | North Carolina | 27705 | United States | Details | |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | United States | Details | |
| Bon Secours Saint Francis Hospital | Greenville | South Carolina | 29607 | United States | Details | |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | United States | Details | |
| West Virginia University Mary Babb Randolph Cancer Center | Morgantown | West Virginia | 26506 | United States | Details | |
| Ziekenhuis Netwerk Antwerpen Stuivenberg | Antwerp | Belgium | Details | |||
| Algemeen Ziekenhuis Sint-Jan Brugge-Oostende | Brugge | Belgium | Details | |||
| Grand Hôpital de Charleroi - Notre Dame | Charleroi | Belgium | Details | |||
| Tom Baker Cancer Center | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| University of Alberta Hospital | Edmonton | Alberta | T6G 2B7 | Canada | Details | |
| Royal Victoria Regional Health Centre | Barrie | Ontario | L4M 6M2 | Canada | Details | |
| Juravinski Cancer Centre | Hamilton | Ontario | L8V 1C3 | Canada | Details | |
| Princess Margaret Hospital | Toronto | Ontario | M5G 2C1 | Canada | Details | |
| Burnaby Hospital | Burnaby | Canada | Details | |||
| Moncton Hospital | Moncton | Canada | Details | |||
| Maisonneuve-Rosemont Hôpital Service d'Hematologie et d'Oncologie Medicale | Montréal | Canada | Details | |||
| Saskatchewan Cancer Agency | Regina | Canada | Details | |||
| Fakultní nemocnice Brno | Brno | Czechia | Details | |||
| Fakultni Nemocnice Hradec Králové | Hradec Králové | Czechia | Details | |||
| Fakultní nemocnice Ostrava | Ostrava | Czechia | Details | |||
| Onkologická klinika Všeobecná fakultní nemocnice v Praze a 1 | Praha 2 | Czechia | Details | |||
| Fakultní Nemocnice Královské Vinohrady | Praha | Czechia | Details | |||
| Aalborg Universitetshospital | Aalborg | Denmark | Details | |||
| Aarhus Universitetshospital | Aarhus | Denmark | Details | |||
| Rigshospitalet | Copenhagen | Denmark | Details | |||
| Odense University Hospital | Odense | Denmark | Details | |||
| Centre Hospitalier Universitaire | La Tronche | France | Details | |||
| Hôpital Dupuytren | Limoges | France | Details | |||
| GHR Mulhouse Sud-Alsace | Mulhouse Cedex | France | Details | |||
| Hôpital Hôtel-Dieu | Nantes | France | Details | |||
| Centre Antoine Lacassagne | Nice | France | Details | |||
| Hôpital Saint Louis | Paris | France | Details | |||
| Centre Hospitalier Lyon Sud | Pierre-Bénite | France | Details | |||
| Centre Hospitalier Universitaire de Toulouse | Toulouse | France | Details | |||
| Städtisches Klinikum Braunschweig | Braunschweig | Germany | Details | |||
| Marien Hospital Düsseldorf | Düsseldorf | Germany | Details | |||
| Universitaetsklinikum Freiburg | Freiburg | Germany | Details | |||
| Universitätsklinikum Halle | Halle | Germany | Details | |||
| Universitätsklinikum Ulm | Ulm | Germany | Details | |||
| Azienda Ospedaliera SS. Antonio E. Biagio E. Cesare Arrigo di Alessandria | Alessandria | Italy | Details | |||
| Azienda Ospedaliero Universitaria Careggi | Firenze | Italy | Details | |||
| Azienda Ospedaliera Universitaria San Martino | Genova | Italy | Details | |||
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milano | Italy | Details | |||
| AORN A. Cardarelli | Napoli | Italy | Details | |||
| Azienda Ospedaliera Universitaria-Maggiore della Carità di Novara | Novara | Italy | Details | |||
| Azienda Ospedaliera Ospedali Riuniti Marche Nord | Pesaro | Italy | Details | |||
| Ospedale S. Eugenio | Roma | Italy | Details | |||
| NHO Nagoya Medical Center | Nagoya-shi | Aichi | Japan | Details | ||
| Narita Red Cross Hospital | Narita | Chiba | Japan | Details | ||
| University of Fukui Hospital | Yoshida | Fukui | Japan | Details | ||
| Chugoku Central Hospital | Fukuyama-shi | Hiroshima | Japan | Details | ||
| Tokai University Hospital | Isehara | Kanagawa | Japan | Details | ||
| Kitasato University Hospital | Sagamihara-shi | Kanagawa | Japan | Details | ||
| Yokohama Municipal Citizen's Hospital | Yokohama | Kanagawa | Japan | Details | ||
| Nagasaki University Hospital | Nagasaki | Nagasaki-shi | Japan | Details | ||
| Kansai Medical University Hirakata | Hirakata | Osaka | Japan | Details | ||
| Kindai University Hospital | Osakasayama-shi | Osaka | Japan | Details | ||
| Saitama Medical Center | Kawagoe | Saitama | Japan | Details | ||
| Nippon Medical School Hospital | Bunkyō-Ku | Tokyo | Japan | Details | ||
| The Cancer Institute Hospital of Japanese Foundation for Cancer Research | Koto | Tokyo | Japan | Details | ||
| NTT Medical Center Tokyo | Shinagawa | Tokyo | Japan | Details | ||
| National Hospital Organization Disaster Medical Center | Tachikawa | Tokyo | Japan | Details | ||
| National Hospital Organization Kyushu | Fukuoka | Japan | Details | |||
| Fukushima Medical University | Fukushima | Japan | Details | |||
| Gifu Municipal Hospital | Gifu | Japan | Details | |||
| National Hospital Organization Kumamoto Medical Center | Kumamoto | Japan | Details | |||
| Japanese Red Cross Kyoto Daini Hospital | Kyoto | Japan | Details | |||
| University Hospital-Kyoto Prefectural University of Medicine | Kyoto | Japan | Details | |||
| Yamagata University Hospital | Yamagata | Japan | Details | |||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Seoul Saint Mary's Hospital | Seoul | 137-701 | Korea, Republic of | Details | ||
| Ulsan University Hospital | Ulsan | 44033 | Korea, Republic of | Details | ||
| Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie | Lublin | Poland | Details | |||
| Instytut Hematologii i Transfuzjologii | Warszawa | Poland | Details | |||
| Samodzielny Publiczny Centralny Szpital Kliniczny | Warszawa | Poland | Details | |||
| Hospital General Universitario de Alicante | Alicante | Spain | Details | |||
| Hospital Universitari Germans Trias i Pujol | Badalona | Spain | Details | |||
| Fundació Hospital de la Santa Creu i Sant Pau | Barcelona | Spain | Details | |||
| Hospital Universitario Vall d'Hebron | Barcelona | Spain | Details | |||
| Hospital San Pedro de Alcantara | Cáceres | Spain | Details | |||
| Hospital de León | León | Spain | Details | |||
| Hospital General Universitario Gregorio Marañon | Madrid | Spain | Details | |||
| Hospital Universitario 12 de Octubre | Madrid | Spain | Details | |||
| Hospital Universitario Ramón Y Cajal | Madrid | Spain | Details | |||
| Hospital Universitario de Salamanca | Salamanca | Spain | Details | |||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | Spain | Details | |||
| Sahlgrenska Universitetssjukhuset, Östra sjukhuset | Göteborg | Sweden | Details | |||
| Universitetssjukhuset Örebro | Örebro | Sweden | Details | |||
| Medway NHS Foundation Trust | Gillingham | United Kingdom | Details | |||
| The Leeds Teaching Hospitals NHS Trust | Leeds | United Kingdom | Details | |||
| Chelsea and Westminster Hospital NHS Foundation Trust | London | United Kingdom | Details | |||
| Nottingham University Hospitals NHS Trust | Nottingham | United Kingdom | Details |