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| NCT ID | NCT02920008 |
| Title | Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Astex Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | POL | ITA | HUN | GBR | FRA | ESP | DNK | DEU | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Southern California | Los Angeles | California | 90033 | United States | Details | |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Franciscan Research Center | Indianapolis | Indiana | 46237 | United States | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601-1915 | United States | Details | |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | 87106 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Weill Cornell Medical College | New York | New York | 10021 | United States | Details | |
| Duke Cancer Institute | Durham | North Carolina | 27710 | United States | Details | |
| University of Oklahoma Medical Center | Oklahoma City | Oklahoma | 73104-5418 | United States | Details | |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Temple University Hospital | Philadelphia | Pennsylvania | 19111-2433 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Baylor Research Institute | Dallas | Texas | 75246 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| West Virginia University Hospitals, Inc. | Morgantown | West Virginia | 26506 | United States | Details | |
| AZ Sint-Jan Brugge-Oostende AV | Brugge | 8000 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium | Details | ||
| Universitair Ziekenhuis Gent | Gent | 9000 | Belgium | Details | ||
| Tom Baker Cancer Centre | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| University of Alberta Hospital | Edmonton | Alberta | T6G 2V2 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2C1 | Canada | Details | |
| McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Hopital Maisonneuve Rosemont | Montreal | H1T 2M4 | Canada | Details | ||
| Aarhus University Hospital | Aarhus C | 8000 | Denmark | Details | ||
| Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
| Centre Hospitalier de la Côte Basque | Bayonne | 64100 | France | Details | ||
| Hôpital de la Conception | Marseille | 13385 | France | Details | ||
| CHRU Montpellier - Saint Eloi | Montpellier | 34295 | France | Details | ||
| Groupe Hospitalier de la Région de Mulhouse et Sud Alsace | Mulhouse | 68100 | France | Details | ||
| Hôpital Saint-Louis | Paris | 75475 | France | Details | ||
| CHU Hopitaux de Bordeaux - Hôpital Haut-Lévêque | Pessac | 33604 | France | Details | ||
| Centre Hospitalier Lyon-Sud | Pierre Bénite | 69310 | France | Details | ||
| Centre Henri Becquerel | Rouen cedex 1 | 76038 | France | Details | ||
| Institut Universitaire du Cancer de Toulouse - Oncopole | Toulouse | 31059 | France | Details | ||
| Universitätsklinikum Leipzig | Leipzig | Sachsen | 4103 | Germany | Details | |
| Städtisches Klinikum Braunschweig gGmbH | Braunschweig | 38114 | Germany | Details | ||
| Marien Hospital Düsseldorf GmbH | Düsseldorf | 40479 | Germany | Details | ||
| Universitätsklinikum Halle (Saale) | Halle | 6120 | Germany | Details | ||
| Universitätsklinikum Schleswig-Holstein | Kiel | 24105 | Germany | Details | ||
| Medizinischen Fakultät Mannheim der Universität Heidelberg | Mannheim | Germany | Details | |||
| Klinikum der Universität München | Muenchen | 81377 | Germany | Details | ||
| Universitätsklinikum Ulm | Ulm | 89081 | Germany | Details | ||
| SE ÁOK I. sz. Belgyógyászati Klinika | Budapest | 1083 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Központ | Debrecen | 4032 | Hungary | Details | ||
| Somogy Megyei Kaposi Mór Oktató Kórház | Kaposvar | 7400 | Hungary | Details | ||
| Pecsi Tudomanyegyetem Klinikai Központ | Pécs | Hungary | Details | |||
| Szegedi Tudományegyetem | Szeged | 6725 | Hungary | Details | ||
| IRCCS AOU San Martino - IST | Genova | 16132 | Italy | Details | ||
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico | Milano | 20122 | Italy | Details | ||
| Ospedale San Raffaele - Milano | Milano | 20132 | Italy | Details | ||
| A.O.R.N. "A. Cardarelli" | Napoli | 80131 | Italy | Details | ||
| A.S.U Integrata di Udine - Presidio Ospedaliero Santa Maria della Misericordia | Udine | 33100 | Italy | Details | ||
| Akita University Hospital | Akita-shi | 010-8543 | Japan | Details | ||
| Chugoku Central Hospital | Fukuyama-Shi | 720-0001 | Japan | Details | ||
| Tokai University Hospital | Isehara-shi | 259-1193 | Japan | Details | ||
| Saitama Medical Center | Kawagoe-Shi | 350-8550 | Japan | Details | ||
| Kobe City Medical Center General Hospital | Kobe-shi | 650-0047 | Japan | Details | ||
| Japanese Red Cross Kyoto Daini Hospital | Kyoto-shi | 602-8026 | Japan | Details | ||
| University Hospital, Kyoto Prefectural University of Medicine | Kyoto-shi | 602-8566 | Japan | Details | ||
| Gunmaken Saiseikai Maebashi Hospital | Maebashi-shi | 371-0821 | Japan | Details | ||
| Nagasaki University Hospital | Nagasaki-shi | 852-8501 | Japan | Details | ||
| The Japanese Red Cross Nagasaki Genbaku Hospital | Nagasaki-Shi | 852-8511 | Japan | Details | ||
| Kindai University Hospital | Osakasayama-Shi | 589-8511 | Japan | Details | ||
| Saga University Hospital | Saga-shi | 849-8501 | Japan | Details | ||
| NTT Medical Center Tokyo | Shinagawa-Ku | 141-8625 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| National Hospital Organization Disaster Medical Center | Tachikawa-Shi | 190-0014 | Japan | Details | ||
| Yamagata University Hospital | Yamagata-Shi | 990-9585 | Japan | Details | ||
| University of Fukui Hospital | Yoshida-Gun | 910-1193 | Japan | Details | ||
| Pusan National University Hospital | Busan | 49241 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 3080 | Korea, Republic of | Details | ||
| Severance Hospital | Seoul | 3722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 5505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 6351 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Seoul St. Mary's Hospital | Seoul | 6591 | Korea, Republic of | Details | ||
| Ulsan University Hospital (UUH) | Ulsan | 44033 | Korea, Republic of | Details | ||
| Instytut Hematologii i Transfuzjologi | Warszawa | 02-776 | Poland | Details | ||
| Hospital Clínic de Barcelona | Barcelona | 8036 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau | Barcelona | 8041 | Spain | Details | ||
| Hospital Duran i Reynals | Barcelona | 8907 | Spain | Details | ||
| Vall d'Hebron Institut d'Oncologia | Barcelona | Spain | Details | |||
| Hospital San Pedro de Alcántara | Cáceres | 10003 | Spain | Details | ||
| Hospital Universitario Reina Sofía | Córdoba | 14004 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañón | Madrid | 28007 | Spain | Details | ||
| Hospital Universitario Central de Asturias | Oviedo | 33011 | Spain | Details | ||
| Hospital Universitario Virgen del Rocío | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitario Dr. Peset | Valencia | 46017 | Spain | Details | ||
| Hospital Universitari i Politècnic La Fe | Valencia | 46026 | Spain | Details | ||
| Sahlgrenska University Hospital | Göteborg | 413 45 | Sweden | Details | ||
| Khmelnytskyi Regional Hospital | Khmelnytskyi | 29000 | Ukraine | Details | ||
| Poltava Regional Clinical Hospital named after M. V. Sklifosovskoho | Poltava | 36011 | Ukraine | Details | ||
| Heart of England NHS Foundation Trust - Heartlands Hospital | Birmingham | B9 5SS | United Kingdom | Details | ||
| University Hospitals Bristol NHS Foundation Trust - Bristol Haematology and Oncology Centre | Bristol | BS2 8ED | United Kingdom | Details | ||
| East Kent Hospitals University NHS Foundation Trust - Kent and Canterbury Hospital | Canterbury | CT1 3NG | United Kingdom | Details | ||
| St. James's University Hospital | Leeds | LS9 7TF | United Kingdom | Details |