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| NCT ID | NCT03016312 |
| Title | IMbassador250: A Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide in Participants With Metastatic Castration-Resistant Prostrate Cancer (mCRPC) After Failure of an Androgen Synthesis Inhibitor And Failure of, Ineligibility For, or Refusal of a Taxane Regimen |
| Acronym | IMbassador250 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | ITA | HUN | GRC | GBR | FRA | ESP | DNK | DEU | CZE | CHE | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope Medical Grp Inc. | Duarte | California | 91010 | United States | Details | |
| University of California San Diego | La Jolla | California | 92037-1337 | United States | Details | |
| Kaiser Permanente San Diego - Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| UC Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| Pacific Hematology Oncology Associates | San Francisco | California | 94115 | United States | Details | |
| University of Colorado; Division of Medical Oncology | Aurora | Colorado | 80021 | United States | Details | |
| Yale School of Medicine | New Haven | Connecticut | 06510-3206 | United States | Details | |
| Stamford Hospital; BCC, MOHR | Stamford | Connecticut | 06904 | United States | Details | |
| Lynn Cancer Institute/Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | United States | Details | |
| SCRI Florida Cancer Specialists South | Fort Myers | Florida | 33916 | United States | Details | |
| Miami Cancer Institute of Baptist Health, Inc. | Miami | Florida | 33176 | United States | Details | |
| Florida Cancer Specialist, North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Investigative Clin Rsch of IN | Indianapolis | Indiana | 46260 | United States | Details | |
| Associates in Oncology/Hematology P.C. | Rockville | Maryland | 20850 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Karmanos Cancer Institute.. | Detroit | Michigan | 48201 | United States | Details | |
| Nebraska Cancer Specialists; Oncology Hematology West, PC | Omaha | Nebraska | 68130 | United States | Details | |
| Urology Cancer Center & GU Research Network | Omaha | Nebraska | 68130 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89128 | United States | Details | |
| MSKCC at Basking Ridge | Basking Ridge | New Jersey | 07920 | United States | Details | |
| New York Oncology Hematology, P.C. | Albany | New York | 12208 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45230 | United States | Details | |
| James Cancer Hospital;Solove Research Institute | Columbus | Ohio | 43210 | United States | Details | |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| Allegheny Cancer Center | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
| University of Pittsburgh Cancer Institute; Division of Medical Oncology | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Miriam Hospital | Providence | Rhode Island | 02906 | United States | Details | |
| Charleston Oncology, P .A | Charleston | South Carolina | 29414 | United States | Details | |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | United States | Details | |
| Sarah Cannon Research Institute / Tennessee Oncology | Chattanooga | Tennessee | 37404 | United States | Details | |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology - Methodist Dallas Cancer Center | Dallas | Texas | 75203 | United States | Details | |
| Texas Oncology, P.A. - Fort Worth | Fort Worth | Texas | 76104 | United States | Details | |
| Texas Oncology - Memorial City | Houston | Texas | 77024 | United States | Details | |
| Texas Oncology-Tyler | Irving | Texas | 75063 | United States | Details | |
| Virginia Cancer Specialists - Alexandria | Alexandria | Virginia | 22304 | United States | Details | |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | United States | Details | |
| Eastern Health; Cancer Services | Box Hill | New South Wales | 3128 | Australia | Details | |
| Concord Repatriation General Hospital; Concord Cancer Centre | Concord | New South Wales | 2139 | Australia | Details | |
| Macquarie University Hospital | Macquarie Park | New South Wales | 2113 | Australia | Details | |
| Royal Brisbane & Women's Hosp; Cancer Care Serv | Herston | Queensland | 4029 | Australia | Details | |
| Adelaide Cancer Centre | Kurralta Park | South Australia | 5037 | Australia | Details | |
| Monash Medical Centre; Oncology | Clayton | Victoria | 3168 | Australia | Details | |
| LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie | Graz | 8036 | Austria | Details | ||
| Ordensklinikum Linz Elisabethinen; Abteilung für Urologie und Andrologie | Linz | 4020 | Austria | Details | ||
| Medizinische Universität Wien; Universitätsklinik für Urologie | Wien | 1090 | Austria | Details | ||
| Onze Lieve Vrouwziekenhuis Aalst | Aalst | 9300 | Belgium | Details | ||
| UZ Gent | Gent | 9000 | Belgium | Details | ||
| CHU Sart-Tilman | Liège | 4000 | Belgium | Details | ||
| Tom Baker Cancer Centre-Calgary | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Kingston General Hospital | Kingston | Ontario | K7L 2V7 | Canada | Details | |
| Lakeridge Health Oshawa; Oncology | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| Princess Margaret Cancer Center | Toronto | Ontario | M5G 1Z5 | Canada | Details | |
| Hopital Charles Lemoyne; Centre Integre de Lutte Contre Le Cancer de La Monteregie | Greenfield Park | Quebec | J4V 2H1 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Centre Hospitalier Universitaire de Sherbrooke - Hopital Fleurimont | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| CHU de Québec - Université Laval - Hôtel-Dieu de Québec | Quebec | G1J 1Z4 | Canada | Details | ||
| Friendship Hospital, Capital Medical University | Beijing | 100050 | China | Details | ||
| Jiangsu Cancer Hospital | Nanjing City | 211100 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Zhongshan Hospital Fudan University | Shanghai | 200032 | China | Details | ||
| Masarykuv onkologicky ustav | Brno | 656 53 | Czechia | Details | ||
| Fakultni nemocnice u sv. Anny v Brne | Brno | 656 91 | Czechia | Details | ||
| Thomayerova nemocnice | Praha 4 - Krc | 140 59 | Czechia | Details | ||
| Aalborg Universitetshospital; Onkologisk Afdeling | Aalborg | 9000 | Denmark | Details | ||
| Herlev Hospital; Afdeling for Kræftbehandling | Herlev | 2730 | Denmark | Details | ||
| Odense Universitetshospital, Onkologisk Afdeling R | Odense C | 5000 | Denmark | Details | ||
| Institut Sainte-Catherine; Oncologie | Avignon | 84082 | France | Details | ||
| Centre Francois Baclesse; Oncologie | Caen | 14076 | France | Details | ||
| Hopital Louis Pasteur; Medecine B | Colmar | 68024 | France | Details | ||
| Centre Oscar Lambret; Chir Cancerologie General | Lille | 59000 | France | Details | ||
| Clinique Chenieux; Oncology | Limoges | 87039 | France | Details | ||
| Hopital Saint Louis, Service D Oncologie Medicale | Paris | 75475 | France | Details | ||
| Hopital d'Instruction des Armees de Begin | Saint-Mande | 94160 | France | Details | ||
| Institut Claudius Regaud; Departement Oncologie Medicale | Toulouse | 31059 | France | Details | ||
| Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Universitätsklinikum Freiburg; Chirurgische Klinik; Abteilung Urologie | Freiburg | 79106 | Germany | Details | ||
| Medizinische Hochschule Hannover; Klinik für Urologie und Onkologische Urologie | Hannover | 30625 | Germany | Details | ||
| Universitätsklinikum Münster, Klinik für Urologie und Kinderurologie | Münster | 48149 | Germany | Details | ||
| Universitätsklinikum Tübingen; Klinik für Urologie | Tübingen | 72076 | Germany | Details | ||
| Urologisches Zentrum Euregio; Würselen, Urologische Praxis am Wasserturm | Würselen | 52146 | Germany | Details | ||
| Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine | Athens | 115 22 | Greece | Details | ||
| Alexandras Hospital; Dept. of Clin. Therapeutics, Athens Uni School of Medicine | Athens | 115 28 | Greece | Details | ||
| Athens Medical Center; Dept. of Oncology | Athens | 151 25 | Greece | Details | ||
| IASO General Hospital of Athens | Athens | 155 62 | Greece | Details | ||
| Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept. | Kifisia | 145 64 | Greece | Details | ||
| University Hospital of Patras Medical Oncology | Patras | 265 04 | Greece | Details | ||
| Papageorgiou General Hospital; Medical Oncology | Thessaloniki | 564 29 | Greece | Details | ||
| Semmelwies University of Medicine; Urology Dept. | Budapest | 1082 | Hungary | Details | ||
| Orszagos Onkologiai Intezet; "C" Belgyógyászati-Onkológiai és Klinikai Farmakológiai Osztály | Budapest | 1122 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Kozpont ; Department of Oncology | Debrecen | 4032 | Hungary | Details | ||
| ISTITUTO NAZIONALE TUMORI IRCCS FONDAZIONE G. PASCALE; Dipartimento Uro-Ginecologico | Napoli | Campania | 80131 | Italy | Details | |
| A.O. Universitaria Policlinico Di Modena; Oncologia | Modena | Emilia-Romagna | 41124 | Italy | Details | |
| Azienda Ospedaliera San Camillo Forlanini; Oncologia Medica | Roma | Lazio | 00152 | Italy | Details | |
| IRCCS AOU San Martino - IST; Oncologia Medica 1 | Genova | Liguria | 16132 | Italy | Details | |
| A.O. Istituti Ospitalieri - Cremona; S.C. Oncologia | Cremona | Lombardia | 26100 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 2 | Milano | Lombardia | 20133 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO); Cure Mediche | Milano | Lombardia | 20141 | Italy | Details | |
| Irccs Ist. Tumori Giovanni Paolo Ii; Dipartimento Oncologia Medica | Bari | Puglia | 70124 | Italy | Details | |
| IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia | San Giovanni Rotondo | Puglia | 71013 | Italy | Details | |
| Ospedale Area Aretina Nord; U.O.C. Oncologia | Arezzo | Toscana | 52100 | Italy | Details | |
| IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Prima | Padova | Veneto | 35128 | Italy | Details | |
| Nagoya City University Hospital | Aichi | 467-8602 | Japan | Details | ||
| National Cancer Center East | Chiba | 277-8577 | Japan | Details | ||
| Toho University Sakura Medical Center | Chiba | 285-8741 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| National Hospital Organization Hokkaido Cancer Center | Hokkaido | 003-0804 | Japan | Details | ||
| Yokohama City University Medical Center | Kanagawa | 232-0024 | Japan | Details | ||
| Kitasato University Hospital | Kanagawa | 252-0375 | Japan | Details | ||
| University Hospital Kyoto Prefectural University of Medicine | Kyoto | 602-8566 | Japan | Details | ||
| Nara Medical University Hospital | Nara | 634-8522 | Japan | Details | ||
| Niigata University Medical & Dental Hospital | Niigata | 951-8520 | Japan | Details | ||
| Kansai Medical University Hospital | Osaka | 573-1191 | Japan | Details | ||
| Toranomon Hospital | Tokyo | 105-8470 | Japan | Details | ||
| The Jikei University Hospital | Tokyo | 105-8471 | Japan | Details | ||
| Nippon Medical School Hospital | Tokyo | 113-8603 | Japan | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Woj. Wielospec. Centrum Onkologii i Traumatologii | ?ód? | 93-513 | Poland | Details | ||
| Medical University of Bialystok; Oncology clinic | Bialystok | 15-027 | Poland | Details | ||
| Przychodnia Lekarska KOMED, Roman Karaszewski | Konin | 62-500 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii | Kraków | 30-688 | Poland | Details | ||
| SPZOZ Opolskie Centrum Onkologii im. Prof. Tadeusza Koszarawskiego | Opole | 45-061 | Poland | Details | ||
| Europejskie Centrum Zdrowia Otwock Szpital im. Fryderyka Chopina, Klinika Onkologii | Otwock | 05-400 | Poland | Details | ||
| Szpital Sw. Elzbiety - Mokotowskie Centrum Medyczne Sp. z o.o. | Warszawa | 02-616 | Poland | Details | ||
| Wojewodzki Szpital; Specjalistyczny ul. | Wroclaw | 51-124 | Poland | Details | ||
| Russian Scientific Center of Roentgenoradiology | Moscow | Moskovskaja Oblast | 117997 | Russian Federation | Details | |
| P.A. Herzen Oncological Inst. ; Oncology | Moscow | Moskovskaja Oblast | 125248 | Russian Federation | Details | |
| SBEI HPE "The First St.Petersburg State Medical University n.a. acad. I.P.Pavlova"of MoH of RF | Sankt-peterburg | Sankt Petersburg | 197022 | Russian Federation | Details | |
| Institut Catala d?Oncologia Hospital Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| Insititut Catala D'Oncologia | Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details | |
| Corporacio Sanitaria Parc Tauli; Servicio de Oncologia | Sabadell | Barcelona | 8208 | Spain | Details | |
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Clinica Universitaria de Navarra; Servicio de Oncologia | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitari Vall d'Hebron; Oncology | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic i Provincial; Servicio de Oncología | Barcelona | 08036 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau; Servicio de Oncologia | Barcelona | 08041 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico San Carlos; Servicio de Oncologia | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Inselspital Bern; Universitätsklinik für Medizinische Onkologie, Klinische Forschungseinheit | Bern | 3010 | Switzerland | Details | ||
| Kantonsspital St. Gallen; Onkologie/Hämatologie | St. Gallen | 9007 | Switzerland | Details | ||
| Taichung Veterans General Hospital; Division of Urology | Taichung | 407 | Taiwan | Details | ||
| National Taiwan University Hospital, Department of Urology | Taipei | 10048 | Taiwan | Details | ||
| TAIPEI VETERANS GENERAL HOSPITAL, Urology | Taipei | 11217 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-LinKou; Urology | Taoyuan | 333 | Taiwan | Details | ||
| Royal Blackburn Hospital | Blackburn | BB2 3HH | United Kingdom | Details | ||
| Leicester Royal Infirmary | Leicester | LE1 5WW | United Kingdom | Details | ||
| Barts and the London NHS Trust. | London | EC1A 7BE | United Kingdom | Details | ||
| Sarah Cannon Research Institute | London | W1G 6AD | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Royal Marsden Hospital; Institute of Cancer Research | Sutton | SM2 5PT | United Kingdom | Details |