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| NCT ID | NCT03093116 |
| Title | A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1) |
| Acronym | TRIDENT-1 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Turning Point Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | child | senior | adult |
| Covered Countries | USA | POL | NLD | ITA | HUN | GBR | FRA | ESP | DNK | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City Of Hope | RECRUITING | Duarte | California | 91010 | United States | Details |
| Adventist Health Glendale | RECRUITING | Glendale | California | 91206 | United States | Details |
| Local Institution - 2136 | NOT_YET_RECRUITING | La Jolla | California | 92037 | United States | Details |
| UC San Diego Health | RECRUITING | La Jolla | California | 92093 | United States | Details |
| Pacific Shores Medical Group | RECRUITING | Long Beach | California | 90813 | United States | Details |
| Local Institution - 1001 | NOT_YET_RECRUITING | Orange | California | 92868 | United States | Details |
| UC Irvine Medical Center | RECRUITING | Orange | California | 92868 | United States | Details |
| St Joseph Heritage Healthcare | RECRUITING | Santa Rosa | California | 95403 | United States | Details |
| Local Institution - 1003 | NOT_YET_RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| University Of Colorado Denver | RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| Georgetown University Medical Center - Lombardi Comprehensive Cancer Center | RECRUITING | Washington | District of Columbia | 20007 | United States | Details |
| The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | RECRUITING | Washington | District of Columbia | 20016 | United States | Details |
| Memorial Healthcare System | RECRUITING | Hollywood | Florida | 33021 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| University Cancer and Blood Center | RECRUITING | Athens | Georgia | 30607 | United States | Details |
| Local Institution - 2134 | COMPLETED | Columbus | Georgia | 31904 | United States | Details |
| University of Chicago | RECRUITING | Chicago | Illinois | 60637 | United States | Details |
| Local Institution - 2142 | COMPLETED | Peoria | Illinois | 61615 | United States | Details |
| Local Institution - 2116 | NOT_YET_RECRUITING | New Orleans | Louisiana | 70121 | United States | Details |
| University of Maryland Medical Center | RECRUITING | Baltimore | Maryland | 21210 | United States | Details |
| Massachusetts General Hospital, | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Local Institution - 1004 | NOT_YET_RECRUITING | Boston | Massachusetts | 02214 | United States | Details |
| Dana Farber Cancer Institute. | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| University Of Michigan | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Karmanos Cancer Institute | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Henry Ford Transplant Institute | RECRUITING | Detroit | Michigan | 48202-2608 | United States | Details |
| Regions Hospital - Cancer Care Center | RECRUITING | Saint Paul | Minnesota | 55101 | United States | Details |
| Central Care Cancer Center | RECRUITING | Bolivar | Missouri | 65613 | United States | Details |
| Washington University Infusion Center Pharmacy | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Rutgers Cancer Institute of New Jersey | RECRUITING | New Brunswick | New Jersey | 08901 | United States | Details |
| Laura & Isaac Perlmutter Cancer Center | RECRUITING | New York | New York | 10016 | United States | Details |
| Local Institution - 1002 | NOT_YET_RECRUITING | New York | New York | 10065 | United States | Details |
| Memorial Sloan Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| Southeastern Medical Oncology Center | RECRUITING | Goldsboro | North Carolina | 27534 | United States | Details |
| Gabrail Cancer Center | RECRUITING | Canton | Ohio | 44718 | United States | Details |
| Trihealth Cancer Institute | RECRUITING | Cincinnati | Ohio | 45220 | United States | Details |
| Cleveland Clinic Main Campus | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| The Ohio State University Wexner Medical Center | RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| Local Institution - 2119 | NOT_YET_RECRUITING | Toledo | Ohio | 43614 | United States | Details |
| Fox Chase Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19111-2497 | United States | Details |
| Baptist Memorial Hospital Baptist Cancer Center | RECRUITING | Memphis | Tennessee | 38120 | United States | Details |
| UT Southwestern Medical Center | RECRUITING | Dallas | Texas | 75390 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Oncology Consultants, P.A. | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Lumi Research | RECRUITING | Kingwood | Texas | 77339 | United States | Details |
| Virginia Cancer Specialists, PC | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| University of Washington-Seattle Cancer Care Alliance | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Local Institution - 2141 | NOT_YET_RECRUITING | Tacoma | Washington | 98405 | United States | Details |
| ThedaCare | RECRUITING | Appleton | Wisconsin | 54911 | United States | Details |
| Chris O'Brien LifeHouse | RECRUITING | Camperdown | New South Wales | 2050 | Australia | Details |
| Flinders Medical Centre | RECRUITING | Adelaide | South Australia | 5042 | Australia | Details |
| Peter MacCallum Cancer Centre | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| Peter MacCallum Cancer Centre - East Melbourne | RECRUITING | East Melbourne | 3002 | Australia | Details | |
| Uza (University Hospital Antwerp) | RECRUITING | Antwerp | 2650 | Belgium | Details | |
| UZ Leuven PHARMACY CLINICAL TRIALS | RECRUITING | Leuven | 3000 | Belgium | Details | |
| Cross Cancer Institute. | RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| Local Institution - 2205 | WITHDRAWN | Vancouver | British Columbia | V5Z 4E7 | Canada | Details |
| Local Institution - 6503 | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| William Osler Health System | RECRUITING | Ontario | L6R 37R | Canada | Details | |
| The Ottawa Hospital | RECRUITING | Ottawa | K1H 8L6 | Canada | Details | |
| Local Institution - 6702 | COMPLETED | Beijing | Beijing | 100021 | China | Details |
| Beijing Cancer Hospital | RECRUITING | Beijing | Beijing | 100142 | China | Details |
| Daping Hospital, the Third Affiliated Hospital of Third Military Medical University /Cancer Center | RECRUITING | Daping | Chongqing | 00000 | China | Details |
| Local Institution - 6719 | COMPLETED | Fuzhou | Fujian | 000000 | China | Details |
| The First Affiliated hospital of Xiamen University-oncology | RECRUITING | Xiamen | Fujian | 361003 | China | Details |
| Guangdong Provincial People'S Hospital | RECRUITING | Guangzhou | Guangdong | 510120 | China | Details |
| The First Affiliated Hospital of Guangzhou Medical University-Pneumology department | RECRUITING | Guangzhou | Guangdong | 510120 | China | Details |
| Local Institution - 6505 | ACTIVE_NOT_RECRUITING | Shenzhen | Guangdong | 518053 | China | Details |
| The Affiliated Tumor Hospital of Harbin Medical University | RECRUITING | Harbin | Heilongjiang | 150081 | China | Details |
| Local Institution - 6504 | ACTIVE_NOT_RECRUITING | Shatin | Hong Kong | 999077 | China | Details |
| Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology/Cancer Center Department | RECRUITING | Wuhan | Hubei | 430022 | China | Details |
| Local Institution - 6705 | COMPLETED | Changsha | Hunan | 410011 | China | Details |
| Hunan Cancer Hospital-thoracic oncology II | RECRUITING | Changsha | Hunan | 410013 | China | Details |
| Nanjing Drum Tower hospital | RECRUITING | Nanjing | Jiangsu | 210008 | China | Details |
| XuZhou Central Hospital/Oncology Department | RECRUITING | Xuzhou City | Jiangsu | 00000 | China | Details |
| Jilin Cancer Hospital/Medical Oncology Department | RECRUITING | Changchun | Jilin | 130012 | China | Details |
| Jilin Cancer Hospital/Medical Oncology Department | RECRUITING | Changchun | Jilin | 130012 | China | Details |
| Local Institution - 6714 | RECRUITING | Changchun | Jilin | 130021 | China | Details |
| Local Institution - 6742 | RECRUITING | Shenyang | Liaoning | 110801 | China | Details |
| Tangdu Hospital | RECRUITING | Xi'an | Shan3xi | 710038 | China | Details |
| Shanxi Bethune Hospital | RECRUITING | Taiyuan | Shanxi | 030032 | China | Details |
| Sichuan Cancer Hospital/Medical Oncology Department | RECRUITING | Chengdu City | Sichuan | 00000 | China | Details |
| Local Institution - 6716 | RECRUITING | Chongqing | Sichuan | 400030 | China | Details |
| Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University | RECRUITING | Hangzhou | Zhejiang | 310016 | China | Details |
| Zhejiang Cancer Hospital-Oncology | RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| The Third Xiangya Hospital of Central South University/Department of Respiratory and Critical Care Medicine | RECRUITING | Changsha | 00000 | China | Details | |
| West China Hospital Sichuan University/Lung cancer center | RECRUITING | Chengdu | 00000 | China | Details | |
| The First Affiliated Hospital - Zhejiang University School of Medicine | RECRUITING | Hangzhou | 310003 | China | Details | |
| Local Institution - 6704 | RECRUITING | Hefei | 230001 | China | Details | |
| Shanghai Chest Hospital | RECRUITING | Shanghai | 200030 | China | Details | |
| Shanghai Chest Hospital | RECRUITING | Shanghai | 200030 | China | Details | |
| Weifang People's Hospital/Medical Oncology Department | RECRUITING | Weifang City | 00000 | China | Details | |
| Henan Cancer Hospital/The 1st pneumology department | RECRUITING | Zhengzhou | 00000 | China | Details | |
| Local Institution - 4901 | COMPLETED | Copenhagen | 2100 | Denmark | Details | |
| Hopital De La Timone | RECRUITING | Marseille | Bouches-du-Rhône | 13005 | France | Details |
| Local Institution - 4207 | COMPLETED | Brest | 29200 | France | Details | |
| Centre Georges-Francois Leclerc | RECRUITING | Dijon Cedex | 21079 | France | Details | |
| Centre Hospitalier Universitarie Grenoble Alpes (Chuga) | RECRUITING | Grenoble Cedex 9 | 38043 | France | Details | |
| Local Institution - 4205 | RECRUITING | Nice | 06189 | France | Details | |
| Local Institution - 4208 | RECRUITING | Poitiers | 86000 | France | Details | |
| Local Institution - 4203 | COMPLETED | St Mande | 94163 | France | Details | |
| Institute Gustave Roussy | RECRUITING | Villejuif | 98405 | France | Details | |
| Local Institution - 4704 | COMPLETED | Berlin | 13125 | Germany | Details | |
| University Clinic Carl Gustav Carus | RECRUITING | Dresden | 01307 | Germany | Details | |
| University Hospital Heidelberg | RECRUITING | Heidelberg | 69120 | Germany | Details | |
| Centrum für Integrierte Onkologie - Universitaetsklinikum Koeln | RECRUITING | Koln | 50937 | Germany | Details | |
| Local Institution - 6502 | ACTIVE_NOT_RECRUITING | Hong Kong | 0 | Hong Kong | Details | |
| Local Institution - 6501 | ACTIVE_NOT_RECRUITING | Hong Kong | Hong Kong | Details | ||
| Semmelweis Egyetem | RECRUITING | Budapest | 1083 | Hungary | Details | |
| Local Institution - 5103 | RECRUITING | Budapest | 1121 | Hungary | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | RECRUITING | Milano | MI | 20133 | Italy | Details |
| Local Institution - 4306 | RECRUITING | Milano | 20122 | Italy | Details | |
| Local Institution - 4307 | WITHDRAWN | Palermo | 90146 | Italy | Details | |
| Centro di Riferimento Oncologico | RECRUITING | Pordenone | 33081 | Italy | Details | |
| Local Institution - 4304 | NOT_YET_RECRUITING | Ravenna | 48121 | Italy | Details | |
| Arcispedale Santa Maria Nuova | RECRUITING | Reggio Emilia | 42123 | Italy | Details | |
| IRCCS Istituto Regina Elena Oncologia Medica 2 | RECRUITING | Roma | 144 | Italy | Details | |
| Azienda Ospedaliera Santa Maria Terni | RECRUITING | Terni | 05100 | Italy | Details | |
| Local Institution - 6609 | RECRUITING | Toon | Ehime | 791-0295 | Japan | Details |
| Local Institution - 6607 | RECRUITING | Sapporo-shi | Hokkaido | 0608648 | Japan | Details |
| Local Institution - 6603 | RECRUITING | Yokohama | Kanagawa | 2418515 | Japan | Details |
| Local Institution - 6605 | RECRUITING | Osaka-shi | Osaka | 5340021 | Japan | Details |
| Local Institution - 6604 | RECRUITING | Chuo-ku | Tokyo | 1040045 | Japan | Details |
| Local Institution - 6606 | RECRUITING | Yonago | Tottori | 683-8504 | Japan | Details |
| National Cancer Center Hospital East | RECRUITING | Kashiwa | 277-8577 | Japan | Details | |
| Local Institution - 6608 | RECRUITING | Nagoya-shi | 466-8560 | Japan | Details | |
| Local Institution - 6602 | RECRUITING | Osaka | 5418567 | Japan | Details | |
| Local Institution - 3003 | NOT_YET_RECRUITING | Seoul | Gangnam-gu | 06351 | Korea, Republic of | Details |
| Chonnam National University Hwasun Hospital | RECRUITING | Hwasun-eup, Hwasun-gun | Jeonnam | 519-763 | Korea, Republic of | Details |
| Local Institution - 3002 | WITHDRAWN | Seoul | Seoul Teugbyeolsi | 03080 | Korea, Republic of | Details |
| Seoul National University Hospital | RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 03080 | Korea, Republic of | Details |
| Samsung Medical Center | RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 06351 | Korea, Republic of | Details |
| Chungbuk National University Hospital | RECRUITING | Cheongju-si | 28644 | Korea, Republic of | Details | |
| Local Institution - 3001 | NOT_YET_RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Yonsei University Health System, Severance Hospital | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Local Institution - 6307 | COMPLETED | Seoul | 05030 | Korea, Republic of | Details | |
| Asan Medical Center | RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Seoul Saint Mary's Hospital | RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| The Netherlands Cancer Institute | RECRUITING | Amsterdam | 1066 CX | Netherlands | Details | |
| Universitair Medisch Centrum Groningen | RECRUITING | Groningen | 9713 GZ | Netherlands | Details | |
| Ośrodek Badań Klinicznych Wczesnych Faz, Uniwersyteckie Centrum Kliniczne | RECRUITING | Gdańsk | 80-214 | Poland | Details | |
| Local Institution - 4604 | COMPLETED | Lublin | 20-609 | Poland | Details | |
| Local Institution - 4605 | COMPLETED | Poznań | 60-693 | Poland | Details | |
| Local Institution - 4603 | COMPLETED | Szczecin | 70-784 | Poland | Details | |
| Klinika Nowotworow Pluca i Klatki Piersiowej | RECRUITING | Warszawa | 02-781 | Poland | Details | |
| National University Hospital | RECRUITING | Singapore | 119074 | Singapore | Details | |
| National Cancer Center Singapore | RECRUITING | Singapore | 169610 | Singapore | Details | |
| Hospital Universitario Dexeus - Grupo Quironsalud | RECRUITING | Barcelona | 08028 | Spain | Details | |
| Hospital Unversitario Val D'Hebrón | RECRUITING | Barcelona | 8035 | Spain | Details | |
| Fundacion Md Anderson | RECRUITING | Madrid | 28033 | Spain | Details | |
| START Madrid-FJD | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario 12 De Octubre | RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital Universitario HM Sanchinarro CIOCC | RECRUITING | Madrid | 28050 | Spain | Details | |
| Local Institution - 4108 | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Instituto Valenciano de Oncología (IVO) - Unidad de Investigación Clínica FINCIVO | RECRUITING | Valencia | 46009 | Spain | Details | |
| Local Institution - 6201 | ACTIVE_NOT_RECRUITING | Taiepi | 100 | Taiwan | Details | |
| Local Institution - 6203 | ACTIVE_NOT_RECRUITING | Tainan | 704 | Taiwan | Details | |
| Local Institution - 6202 | COMPLETED | Taipei | 10449 | Taiwan | Details | |
| The Royal Marsden NHS Foundation Trust | RECRUITING | London | SW3 6JJ | United Kingdom | Details | |
| Local Institution - 4402 | COMPLETED | London | W12 OHS | United Kingdom | Details | |
| Sarah Cannon Research Institute Central Office | RECRUITING | London | W1G 6AD | United Kingdom | Details | |
| The Christie NHS Foundation Trust | RECRUITING | Manchester | M20 4BX | United Kingdom | Details | |
| The Royal Marsden NHS Foundation Trust | RECRUITING | Sutton | SM2 5PT | United Kingdom | Details |