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| NCT ID | NCT03213691 |
| Title | Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Children's Hospital of Alabama | Birmingham | Alabama | 35233 | United States | Details | |
| Banner Children's at Desert | Mesa | Arizona | 85202 | United States | Details | |
| Phoenix Childrens Hospital | Phoenix | Arizona | 85016 | United States | Details | |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202-3591 | United States | Details | |
| Kaiser Permanente Downey Medical Center | Downey | California | 90242 | United States | Details | |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | United States | Details | |
| Miller Children's and Women's Hospital Long Beach | Long Beach | California | 90806 | United States | Details | |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| Mattel Children's Hospital UCLA | Los Angeles | California | 90095 | United States | Details | |
| Valley Children's Hospital | Madera | California | 93636 | United States | Details | |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | United States | Details | |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | United States | Details | |
| Lucile Packard Children's Hospital Stanford University | Palo Alto | California | 94304 | United States | Details | |
| UCSF Medical Center-Mission Bay | San Francisco | California | 94158 | United States | Details | |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | United States | Details | |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Denver | Colorado | 80218 | United States | Details | |
| Yale University | New Haven | Connecticut | 06520 | United States | Details | |
| Alfred I duPont Hospital for Children | Wilmington | Delaware | 19803 | United States | Details | |
| Children's National Medical Center | Washington | District of Columbia | 20010 | United States | Details | |
| University of Florida Health Science Center - Gainesville | Gainesville | Florida | 32610 | United States | Details | |
| Nemours Children's Clinic-Jacksonville | Jacksonville | Florida | 32207 | United States | Details | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | United States | Details | |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | United States | Details | |
| Arnold Palmer Hospital for Children | Orlando | Florida | 32806 | United States | Details | |
| Nemours Children's Hospital | Orlando | Florida | 32827 | United States | Details | |
| Nemours Children's Clinic - Pensacola | Pensacola | Florida | 32504 | United States | Details | |
| Johns Hopkins All Children's Hospital | Saint Petersburg | Florida | 33701 | United States | Details | |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Tampa | Florida | 33607 | United States | Details | |
| Saint Mary's Hospital | West Palm Beach | Florida | 33407 | United States | Details | |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital | Atlanta | Georgia | 30329 | United States | Details | |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | United States | Details | |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | United States | Details | |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | United States | Details | |
| Lurie Children's Hospital-Chicago | Chicago | Illinois | 60611 | United States | Details | |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | United States | Details | |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | United States | Details | |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | United States | Details | |
| Blank Children's Hospital | Des Moines | Iowa | 50309 | United States | Details | |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | United States | Details | |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | United States | Details | |
| Children's Hospital New Orleans | New Orleans | Louisiana | 70118 | United States | Details | |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | United States | Details | |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | United States | Details | |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | United States | Details | |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| C S Mott Children's Hospital | Ann Arbor | Michigan | 48109 | United States | Details | |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Minneapolis | Minnesota | 55404 | United States | Details | |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | United States | Details | |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States | Details | |
| Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | United States | Details | |
| Cardinal Glennon Children's Medical Center | Saint Louis | Missouri | 63104 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Mercy Hospital Saint Louis | Saint Louis | Missouri | 63141 | United States | Details | |
| Children's Hospital and Medical Center of Omaha | Omaha | Nebraska | 68114 | United States | Details | |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | United States | Details | |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | United States | Details | |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | 89135 | United States | Details | |
| Summerlin Hospital Medical Center | Las Vegas | Nevada | 89144 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Morristown Medical Center | Morristown | New Jersey | 07960 | United States | Details | |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| The Steven and Alexandra Cohen Children's Medical Center of New York | New Hyde Park | New York | 11040 | United States | Details | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | United States | Details | |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | United States | Details | |
| Mission Hospital | Asheville | North Carolina | 28801 | United States | Details | |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | United States | Details | |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | United States | Details | |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States | Details | |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | United States | Details | |
| Dayton Children's Hospital | Dayton | Ohio | 45404 | United States | Details | |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo | Ohio | 43606 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Legacy Emanuel Children's Hospital | Portland | Oregon | 97227 | United States | Details | |
| Oregon Health and Science University | Portland | Oregon | 97239 | United States | Details | |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | United States | Details | |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| BI-LO Charities Children's Cancer Center | Greenville | South Carolina | 29605 | United States | Details | |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | United States | Details | |
| East Tennessee Childrens Hospital | Knoxville | Tennessee | 37916 | United States | Details | |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105 | United States | Details | |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | United States | Details | |
| Dell Children's Medical Center of Central Texas | Austin | Texas | 78723 | United States | Details | |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | United States | Details | |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | United States | Details | |
| Cook Children's Medical Center | Fort Worth | Texas | 76104 | United States | Details | |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | United States | Details | |
| M D Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Children's Hospital of San Antonio | San Antonio | Texas | 78207 | United States | Details | |
| Methodist Children's Hospital of South Texas | San Antonio | Texas | 78229 | United States | Details | |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | United States | Details | |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | United States | Details | |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | United States | Details | |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23507 | United States | Details | |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | United States | Details | |
| Seattle Children's Hospital | Seattle | Washington | 98105 | United States | Details | |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99204 | United States | Details | |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | United States | Details | |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | United States | Details | |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | United States | Details | |
| Children's Hospital of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| San Jorge Children's Hospital | San Juan | 00912 | Puerto Rico | Details | ||
| University Pediatric Hospital | San Juan | 00926 | Puerto Rico | Details |