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| NCT ID | NCT03221426 |
| Title | Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | LVA | LTU | ITA | ISR | GBR | FRA | EST | DEU | CAN | BRA | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope ( Site 0005) | Duarte | California | 91010 | United States | Details | |
| Yale Cancer Center ( Site 0016) | New Haven | Connecticut | 06520 | United States | Details | |
| Georgetown University ( Site 0015) | Washington | District of Columbia | 20007 | United States | Details | |
| Northwestern University - Robert H. Lurie Comprehensive Cancer Center ( Site 0018) | Chicago | Illinois | 60611 | United States | Details | |
| The University of Chicago Medical Center ( Site 0004) | Chicago | Illinois | 60637 | United States | Details | |
| Roswell Park Cancer Institute ( Site 0001) | Buffalo | New York | 14263 | United States | Details | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0019) | New York | New York | 10016 | United States | Details | |
| Memorial Sloan Kettering ( Site 0024) | New York | New York | 10065 | United States | Details | |
| Weill Cornell Medical Center ( Site 0023) | New York | New York | 10065 | United States | Details | |
| University of Rochester ( Site 0011) | Rochester | New York | 14642 | United States | Details | |
| Fox Chase Cancer Center ( Site 0006) | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Temple University Hospital ( Site 0026) | Philadelphia | Pennsylvania | 19140 | United States | Details | |
| University of Utah, Huntsman Cancer Institute ( Site 0012) | Salt Lake City | Utah | 84112 | United States | Details | |
| Virginia Cancer Specialists, PC ( Site 0010) | Fairfax | Virginia | 22031 | United States | Details | |
| Institut Jules Bordet ( Site 0480) | Brussels | Bruxelles-Capitale, Region De | 1000 | Belgium | Details | |
| Hopital Erasme ULB ( Site 0484) | Brussels | Bruxelles-Capitale, Region De | 1070 | Belgium | Details | |
| UCL Saint Luc ( Site 0479) | Bruxelles | Bruxelles-Capitale, Region De | 1200 | Belgium | Details | |
| Grand Hopital de Charleroi ( Site 0478) | Charleroi | Hainaut | 6000 | Belgium | Details | |
| CHU de Liege ( Site 0482) | Liège | Liege | 4000 | Belgium | Details | |
| CHU UCL Namur Site de Godinne ( Site 0485) | Yvoir | Namur | 5530 | Belgium | Details | |
| UZ Gent ( Site 0486) | Gent | Oost-Vlaanderen | 9000 | Belgium | Details | |
| UZ Leuven ( Site 0483) | Leuven | Vlaams-Brabant | 3000 | Belgium | Details | |
| AZ Groeninge ( Site 0481) | Kortrijk | West-Vlaanderen | 8500 | Belgium | Details | |
| Instituto do Cancer do Ceara ( Site 0311) | Fortaleza | Ceara | 60430-230 | Brazil | Details | |
| Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 0308) | Porto Alegre | Rio Grande Do Sul | 90610-000 | Brazil | Details | |
| CEPON - Centro de Pesquisas Oncologicas ( Site 0302) | Florianopolis | Santa Catarina | 88034-000 | Brazil | Details | |
| Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 0301) | Barretos | Sao Paulo | 14784-400 | Brazil | Details | |
| Hospital de Base de Sao Jose de Rio Preto ( Site 0304) | Sao Jose Rio Preto | Sao Paulo | 15090-000 | Brazil | Details | |
| Instituto Nacional Do Cancer Jose Alencar Gomes Da Silva ( Site 0307) | Rio de Janeiro | 20230-130 | Brazil | Details | ||
| Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0305) | Sao Paulo | 01246-000 | Brazil | Details | ||
| Hospital Israelita Albert Einstein ( Site 0309) | Sao Paulo | 05652-900 | Brazil | Details | ||
| Cross Cancer Institute ( Site 0033) | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Moncton Hospital - Horizon Health Network ( Site 0038) | Moncton | New Brunswick | E1C 6Z8 | Canada | Details | |
| Sunnybrook Research Institute ( Site 0032) | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| CISSS de la Monteregie-Centre ( Site 0039) | Greenfield Park | Quebec | J4V 2H1 | Canada | Details | |
| CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0040) | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Jewish General Hospital ( Site 0034) | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0035) | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| CHU de Quebec - Hotel-Dieu de Quebec ( Site 0042) | Quebec | G1R 2J6 | Canada | Details | ||
| Instituto Clinico del Sur. ICOS ( Site 0290) | Temuco | Araucania | 4810469 | Chile | Details | |
| Hospital Regional Rancagua Libertador Bernardo O Higgins ( Site 0299) | Rancagua | Lbtdr Gen Bernardo O Higgins | 2820000 | Chile | Details | |
| Fundacion Arturo Lopez Perez FALP ( Site 0286) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Pontificia Universidad Catolica de Chile ( Site 0285) | Santiago | Region M. De Santiago | 8330032 | Chile | Details | |
| Hospital Clinico Universidad de Chile ( Site 0287) | Santiago | Region M. De Santiago | 8380456 | Chile | Details | |
| Beijing Cancer Hospital ( Site 0221) | Beijing | Beijing | 100142 | China | Details | |
| Zhejiang Cancer Hospital ( Site 0231) | Hangzhou | Zhejiang | 310022 | China | Details | |
| Sir Run Run Shaw Hospital ( Site 0233) | Hangzhou | Zhejiang | 430030 | China | Details | |
| SA Pohja-Eesti Regionaalhaigla ( Site 0526) | Tallinn | Harjumaa | 13419 | Estonia | Details | |
| Hopital Prive Jean Mermoz ( Site 0462) | Lyon | Auvergne | 69008 | France | Details | |
| Institut Paoli Calmettes ( Site 0472) | Marseille | Bouches-du-Rhone | 13009 | France | Details | |
| CHU Reims - Hopital Robert Debre ( Site 0465) | Reims | Champagne-Ardenne | 51092 | France | Details | |
| CHU Brest - Institut de Cancerologie et d Hematologie ( Site 0474) | Brest | Finistere | 29200 | France | Details | |
| CHU Toulouse - Hopital Rangueil ( Site 0470) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Institut du Cancer de Montpellier ( Site 0473) | Montpellier | Herault | 34298 | France | Details | |
| Centre Eugene Marquis ( Site 0466) | Rennes | Ille-et-Vilaine | 35042 | France | Details | |
| Institut de Cancerologie de l Ouest Centre Rene Gauducheau ( Site 0469) | Saint Herblain | Loire-Atlantique | 44805 | France | Details | |
| CHRU Lille - Hopital Claude Huriez ( Site 0461) | Lille | Nord | 59037 | France | Details | |
| CHU Poitiers - Pole Regional de Cancerologie ( Site 0467) | Poitiers | Vienne | 86021 | France | Details | |
| CHU Hopital Saint Antoine ( Site 0471) | Paris | 75012 | France | Details | ||
| Institut Mutualiste Montsouris ( Site 0463) | Paris | 75014 | France | Details | ||
| Klinikum Esslingen GmbH ( Site 0453) | Esslingen | Baden-Wurttemberg | 73730 | Germany | Details | |
| Universitaetsklinikum Freiburg ( Site 0450) | Freiburg | Baden-Wurttemberg | 79106 | Germany | Details | |
| Klinikum der Universitaet in Muenchen ( Site 0446) | Muenchen | Bayern | 81377 | Germany | Details | |
| Medizinische Hochschule Hannover ( Site 0449) | Hannover | Niedersachsen | 30625 | Germany | Details | |
| Kliniken Essen Mitte Gmbh Evang. Huyssens Stiftung ( Site 0445) | Essen | Nordrhein-Westfalen | 45136 | Germany | Details | |
| Medizinische klinilk und Poliklinik Johannes Gutenberg Univ ( Site 0455) | Mainz | Rheinland-Pfalz | 55131 | Germany | Details | |
| Universitaetsklinikum Carl Gustav Carus der TU Dresden ( Site 0448) | Dresden | Sachsen | 01307 | Germany | Details | |
| Haematologisch-Onkologische Praxis Eppendorf Facharztzentrum Eppendorf - Hope ( Site 0454) | Hamburg | 20249 | Germany | Details | ||
| Integra Cancer Institute ( Site 0262) | Guatemala | 01010 | Guatemala | Details | ||
| Grupo Medico Angeles ( Site 0261) | Guatemala | 01015 | Guatemala | Details | ||
| Centro Medico Integral De Cancerología (CEMIC) ( Site 0260) | Quetzaltenango | 09002 | Guatemala | Details | ||
| Soroka University M.C ( Site 0385) | Beer Sheva | HaDarom | 8410101 | Israel | Details | |
| Meir medical center ( Site 0386) | Kfar Saba | HaMerkaz | 4428164 | Israel | Details | |
| Sourasky Medical Center. ( Site 0382) | Tel-Aviv | Tell Abib | 6423906 | Israel | Details | |
| Rambam Health Care Campus ( Site 0381) | Haifa | 31096 | Israel | Details | ||
| Hadassah Medical Center. Ein Kerem ( Site 0383) | Jerusalem | 9112001 | Israel | Details | ||
| Rabin-Medical Center ( Site 0384) | Petah Tikva | 4941492 | Israel | Details | ||
| Sheba Medical center ( Site 0387) | Ramat Gan | 5265601 | Israel | Details | ||
| IRCCS Istituto Oncologico Veneto ( Site 0431) | Padova | Abruzzo | 35128 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0430) | Milano | Lombardia | 20133 | Italy | Details | |
| Istituto Clinico Humanitas Research Hospital ( Site 0432) | Rozzano | Milano | 20089 | Italy | Details | |
| IRCCS Policlinico San Donato ( Site 0433) | San Donato Milanese | Milano | 20097 | Italy | Details | |
| Azienda Ospedaliero Universitaria di Modena Policlinico ( Site 0429) | Modena | 41125 | Italy | Details | ||
| Seconda Universita Napoli ( Site 0436) | Napoli | 80131 | Italy | Details | ||
| A.O.U. Santa Maria della Misericordia di Udine ( Site 0434) | Udine | 33100 | Italy | Details | ||
| Aichi Cancer Center Hospital ( Site 0165) | Nagoya | Aichi | 464-8681 | Japan | Details | |
| National Cancer Center Hospital East ( Site 0178) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center ( Site 0186) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Hokkaido University Hospital ( Site 0160) | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Hyogo Cancer Center ( Site 0182) | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Kobe University Hospital ( Site 0188) | Kobe | Hyogo | 650-0017 | Japan | Details | |
| Kobe City Medical Center General Hospital ( Site 0181) | Kobe | Hyogo | 650-0047 | Japan | Details | |
| Ibaraki Prefectural Central Hospital ( Site 0177) | Kasama | Ibaraki | 309-1793 | Japan | Details | |
| Iwate Medical University Hospital ( Site 0184) | Shiwa-gun | Iwate | 028-3695 | Japan | Details | |
| St. Marianna University School of Medicine Hospital ( Site 0187) | Kawasaki | Kanagawa | 216-8511 | Japan | Details | |
| Kanagawa Cancer Center ( Site 0167) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Kansai Medical University Hospital ( Site 0190) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| Osaka University Hospital ( Site 0162) | Suita | Osaka | 565-0871 | Japan | Details | |
| Osaka Medical College Hospital ( Site 0168) | Takatsuki | Osaka | 569-8686 | Japan | Details | |
| Saitama Cancer Center ( Site 0170) | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Shizuoka Cancer Center Hospital and Research Institute ( Site 0176) | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| Chiba Cancer Center ( Site 0180) | Chiba | 260-8717 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center ( Site 0172) | Fukuoka | 811-1395 | Japan | Details | ||
| Kyushu University Hospital ( Site 0173) | Fukuoka | 812-8582 | Japan | Details | ||
| Gifu University Hospital ( Site 0166) | Gifu | 501-1194 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital ( Site 0171) | Hiroshima | 730-8518 | Japan | Details | ||
| Kochi Health Sciences Center ( Site 0189) | Kochi | 781-8555 | Japan | Details | ||
| Kumamoto University Hospital ( Site 0164) | Kumamoto | 860-8556 | Japan | Details | ||
| Niigata Cancer Center Hospital ( Site 0169) | Niigata | 951-8566 | Japan | Details | ||
| Osaka International Cancer Institute ( Site 0161) | Osaka | 541-8567 | Japan | Details | ||
| Osaka General Medical Center ( Site 0159) | Osaka | 558-8558 | Japan | Details | ||
| National Cancer Center Hospital ( Site 0179) | Tokyo | 104-0045 | Japan | Details | ||
| Tokyo Metropolitan Komagome Hospital ( Site 0183) | Tokyo | 113-8677 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR ( Site 0185) | Tokyo | 135-8550 | Japan | Details | ||
| Toyama Prefectural Central Hospital ( Site 0163) | Toyama | 930-8550 | Japan | Details | ||
| Chonnam National University Hwasun Hospital ( Site 0083) | Hwasun Gun | Jeonranamdo | 58128 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital ( Site 0085) | Seongnam-si | Kyonggi-do | 13620 | Korea, Republic of | Details | |
| Kyungpook National University Chilgok Hospital ( Site 0089) | Daegu | Taegu-Kwangyokshi | 41404 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center ( Site 0087) | Incheon | 21565 | Korea, Republic of | Details | ||
| Korea University Anam Hospital ( Site 0084) | Seoul | 02841 | Korea, Republic of | Details | ||
| Seoul National University Hospital -SNUH- ( Site 0080) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System ( Site 0081) | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center ( Site 0082) | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital ( Site 0088) | Seoul | 06273 | Korea, Republic of | Details | ||
| SMG-SNU BORAMAE Medical Center ( Site 0086) | Seoul | 07061 | Korea, Republic of | Details | ||
| Riga East Clinical University Hospital ( Site 0550) | Riga | 1079 | Latvia | Details | ||
| LSMUL Kauno Klinikos ( Site 0570) | Kaunas | 50161 | Lithuania | Details | ||
| Nacionalinis Vezio Institutas ( Site 0569) | Vilnius | 08406 | Lithuania | Details | ||
| Vilniaus Universiteto Ligonine Santaros Klinikos ( Site 0568) | Vilnius | 08460 | Lithuania | Details | ||
| Hospital Kuala Lumpur ( Site 0146) | Kuala Lumpur | 50586 | Malaysia | Details | ||
| University Malaya Medical Centre ( Site 0143) | Kuala Lumpur | 59100 | Malaysia | Details | ||
| St. Luke s Medical Center ( Site 0622) | Quezon City | National Capital Region | 1102 | Philippines | Details | |
| Wojewodzki Szpital Specjalistyczny we Wroclawiu ( Site 0358) | Wroclaw | Dolnoslaskie | 51-124 | Poland | Details | |
| Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 0351) | Lublin | Lubelskie | 20-080 | Poland | Details | |
| Szpital Uniwersytecki w Krakowie ( Site 0352) | Krakow | Malopolskie | 31-501 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0349) | Warszawa | Mazowieckie | 02-034 | Poland | Details | |
| Mazowiecki Szpital Onkologiczny ( Site 0363) | Wieliszew | Mazowieckie | 05-135 | Poland | Details | |
| Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0353) | Koscierzyna | Pomorskie | 83-400 | Poland | Details | |
| Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 0354) | Bielsko-Biala | Slaskie | 43-300 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0361) | Gliwice | Slaskie | 44-101 | Poland | Details | |
| SPZOZ WSS nr 3 w Rybniku ( Site 0357) | Rybnik | Slaskie | 44-200 | Poland | Details | |
| Kaluga Regional Clinical Oncology Center ( Site 0345) | Kaluga | Kaluzskaja Oblast | 248007 | Russian Federation | Details | |
| SBHI Leningrad Regional Clinical Hospital ( Site 0496) | Saint Petersburg | Leningradskaya Oblast | 194291 | Russian Federation | Details | |
| National Medical and Surgical Center n.a. N.I.Pirogov ( Site 0338) | Moscow | Moskva | 105203 | Russian Federation | Details | |
| Blokhin National Medical Oncology ( Site 0494) | Moscow | Moskva | 115478 | Russian Federation | Details | |
| Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0344) | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| Leningrad Regional Oncology Center ( Site 0335) | Saint-Petersburg | Sankt-Peterburg | 188663 | Russian Federation | Details | |
| City clinical oncological dispensary ( Site 0336) | Sankt-Petersburg | Sankt-Peterburg | 198255 | Russian Federation | Details | |
| Tomsk Scientific Research Institute of Oncology ( Site 0337) | Tomsk | Tomskaya Oblast | 634028 | Russian Federation | Details | |
| National University Hospital ( Site 0095) | Singapore | Central Singapore | 119074 | Singapore | Details | |
| National Cancer Centre Singapore ( Site 0097) | Singapore | Central Singapore | 169610 | Singapore | Details | |
| Oncocare Cancer Centre ( Site 0096) | Singapore | Central Singapore | 258499 | Singapore | Details | |
| Taipei Medical University Shuang Ho Hospital ( Site 0068) | New Taipei | 235 | Taiwan | Details | ||
| National Cheng Kung University Hospital ( Site 0067) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital ( Site 0063) | Taipei | 10002 | Taiwan | Details | ||
| Mackay Memorial Hospital ( Site 0065) | Taipei | 104 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center ( Site 0066) | Taipei | 11259 | Taiwan | Details | ||
| Chang Gung Medical Foundation. Linkou ( Site 0064) | Taoyuan | 333 | Taiwan | Details | ||
| City Clinical Hosp.4 of DCC ( Site 0325) | Dnipro | Dnipropetrovska Oblast | 49102 | Ukraine | Details | |
| MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional Council ( Site 0589) | Kryviy Rih | Dnipropetrovska Oblast | 50048 | Ukraine | Details | |
| Ivano-Frankivsk Regional Oncology Clinical Dispensary ( Site 0321) | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
| Communal non profit enterprise Regional Clinical Oncology Center ( Site 0591) | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details | |
| National Cancer Institute of the MoH of Ukraine ( Site 0319) | Kyiv | Kyivska Oblast | 03022 | Ukraine | Details | |
| Kyiv City Clinical Oncology Center ( Site 0590) | Kyiv | Kyivska Oblast | 03115 | Ukraine | Details | |
| University Hospitals Bristol NHS Foundation Trust ( Site 0407) | Bristol | Bristol, City Of | BS2 8ED | United Kingdom | Details | |
| Ninewells Hospital and Medical School ( Site 0406) | Dundee | Dundee City | DD1 9SY | United Kingdom | Details | |
| Royal Free London NHS Foundation Trust ( Site 0403) | London | London, City Of | NW3 2QG | United Kingdom | Details | |
| The Royal Marsden Foundation Trust ( Site 0405) | London | London, City Of | SW3 6JJ | United Kingdom | Details | |
| Imperial College Healthcare NHS Trust ( Site 0402) | London | London, City Of | W2 1NY | United Kingdom | Details | |
| Royal Marsden NHS Foundation Trust ( Site 0400) | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| The Christie NHS Foundation Trust ( Site 0397) | Manchester | M20 4BX | United Kingdom | Details |