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| NCT ID | NCT03224767 |
| Title | Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Alliance for Clinical Trials in Oncology |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | United States | Details | |
| Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | 95603 | United States | Details | |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | United States | Details | |
| Mills-Peninsula Medical Center | Burlingame | California | 94010 | United States | Details | |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | 95682 | United States | Details | |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | United States | Details | |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | United States | Details | |
| Memorial Medical Center | Modesto | California | 95355 | United States | Details | |
| Palo Alto Medical Foundation-Camino Division | Mountain View | California | 94040 | United States | Details | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | United States | Details | |
| Palo Alto Medical Foundation Health Care | Palo Alto | California | 94301 | United States | Details | |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | 95661 | United States | Details | |
| Sutter Roseville Medical Center | Roseville | California | 95661 | United States | Details | |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | United States | Details | |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | United States | Details | |
| Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | 94086 | United States | Details | |
| Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | 95687 | United States | Details | |
| Sutter Solano Medical Center/Cancer Center | Vallejo | California | 94589 | United States | Details | |
| Smilow Cancer Center/Yale-New Haven Hospital | New Haven | Connecticut | 06510 | United States | Details | |
| Yale University | New Haven | Connecticut | 06520 | United States | Details | |
| Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut | 06611 | United States | Details | |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | United States | Details | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | United States | Details | |
| Tampa General Hospital | Tampa | Florida | 33606 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | United States | Details | |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | United States | Details | |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | United States | Details | |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | United States | Details | |
| Rush University Medical Center | Chicago | Illinois | 60612 | United States | Details | |
| Central Care Cancer Center - Garden City | Garden City | Kansas | 67846 | United States | Details | |
| Central Care Cancer Center - Great Bend | Great Bend | Kansas | 67530 | United States | Details | |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Tufts Medical Center | Boston | Massachusetts | 02111 | United States | Details | |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | United States | Details | |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | United States | Details | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | United States | Details | |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | United States | Details | |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | United States | Details | |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | United States | Details | |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | United States | Details | |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | United States | Details | |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | United States | Details | |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | United States | Details | |
| Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | 49444 | United States | Details | |
| Corewell Health Reed City Hospital | Reed City | Michigan | 49677 | United States | Details | |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | United States | Details | |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | United States | Details | |
| Munson Medical Center | Traverse City | Michigan | 49684 | United States | Details | |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | United States | Details | |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | United States | Details | |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | United States | Details | |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | United States | Details | |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | United States | Details | |
| Unity Hospital | Fridley | Minnesota | 55432 | United States | Details | |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | United States | Details | |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | United States | Details | |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | United States | Details | |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | United States | Details | |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | United States | Details | |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | United States | Details | |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | United States | Details | |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | United States | Details | |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | United States | Details | |
| Regions Hospital | Saint Paul | Minnesota | 55101 | United States | Details | |
| United Hospital | Saint Paul | Minnesota | 55102 | United States | Details | |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | United States | Details | |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | United States | Details | |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | United States | Details | |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | United States | Details | |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | United States | Details | |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | United States | Details | |
| Research Medical Center | Kansas City | Missouri | 64132 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | United States | Details | |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | United States | Details | |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | United States | Details | |
| Great Falls Clinic | Great Falls | Montana | 59405 | United States | Details | |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | United States | Details | |
| Community Medical Center | Missoula | Montana | 59804 | United States | Details | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | United States | Details | |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07101 | United States | Details | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | United States | Details | |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | United States | Details | |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | United States | Details | |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | United States | Details | |
| Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | 73505 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| M D Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Farmington Health Center | Farmington | Utah | 84025 | United States | Details | |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | United States | Details | |
| South Jordan Health Center | South Jordan | Utah | 84009 | United States | Details | |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | United States | Details | |
| FHCC South Lake Union | Seattle | Washington | 98109 | United States | Details | |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | United States | Details | |
| University of Washington Medical Center - Montlake | Seattle | Washington | 98195 | United States | Details | |
| United Hospital Center | Bridgeport | West Virginia | 26330 | United States | Details | |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | United States | Details | |
| Camden Clark Medical Center | Parkersburg | West Virginia | 26101 | United States | Details | |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | United States | Details | |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | United States | Details | |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | United States | Details |