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| NCT ID | NCT03260322 |
| Title | A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Astellas Pharma Global Development, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | GBR | ESP | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Honor Health Research Institute | Scottsdale | Arizona | 85258 | United States | Details | |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | United States | Details | |
| University of California Los Angeles | Los Angeles | California | 90095 | United States | Details | |
| University of California, Davis | Sacramento | California | 95817 | United States | Details | |
| University of California, San Francisco | San Francisco | California | 94115 | United States | Details | |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | United States | Details | |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| University of Kansas Cancer Center | Fairway | Kansas | 66205 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| University Hospital of Cleveland | Cleveland | Ohio | 44106 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Mary Crowley Research Center | Dallas | Texas | 75251 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-3522 | United States | Details | |
| Site CA15004 | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Site CA15003 | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Site CA15001 | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Site CA15002 | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Site IT39004 | Ancona | Italy | Details | |||
| Site IT39002 | Milano | Italy | Details | |||
| Site IT39003 | Milano | Italy | Details | |||
| Site IT39008 | Milano | Italy | Details | |||
| Site IT39009 | Milano | Italy | Details | |||
| Site IT39010 | Modena | Italy | Details | |||
| Site IT39005 | Monza | Italy | Details | |||
| Site IT39011 | Negrar | Italy | Details | |||
| Site JP81001 | Chuo-ku | Japan | Details | |||
| Site KR82004 | Goyang-si | Gyeonggi-do | 410-769 | Korea, Republic of | Details | |
| Site KR82005 | Seongnam-Si | Gyeonggi-do | 013620 | Korea, Republic of | Details | |
| Site KR82001 | Seoul | 03080 | Korea, Republic of | Details | ||
| SIte KR82002 | Seoul | 120-752 | Korea, Republic of | Details | ||
| Site KR82006 | Seoul | Korea, Republic of | Details | |||
| Site PT35101 | Lisboa | Portugal | Details | |||
| Site PT35106 | Porto | Portugal | Details | |||
| Site ES34002 | Barcelona | Spain | Details | |||
| Site ES34003 | Barcelona | Spain | Details | |||
| Site ES34009 | Barcelona | Spain | Details | |||
| Site ES34010 | Barcelona | Spain | Details | |||
| Site ES34001 | Madrid | Spain | Details | |||
| Site ES34006 | Madrid | Spain | Details | |||
| Site ES34013 | Madrid | Spain | Details | |||
| Site ES34014 | Valencia | Spain | Details | |||
| Site TW88602 | Taichung | 00404 | Taiwan | Details | ||
| Site TW88601 | Tainan | Taiwan | Details | |||
| Site TW88603 | Taipei City | Taiwan | Details | |||
| Site GB44003 | London | United Kingdom | Details | |||
| Site GB44006 | London | United Kingdom | Details | |||
| Site GB44004 | Newcastle upon Tyne | United Kingdom | Details | |||
| Site GB44005 | Sutton Surry | United Kingdom | Details |