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| NCT ID | NCT03273153 |
| Title | A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | NLD | ITA | HUN | GRC | GBR | FRA | ESP | DEU | BRA | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | United States | Details | |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | United States | Details | |
| USC Norris Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| USC Norris Cancer Center; USC Oncology Hematology Newport Beach | Newport Beach | California | 92663 | United States | Details | |
| University of California at Irvine Medical Center; Department of Oncology | Orange | California | 92868 | United States | Details | |
| Stanford Comprehensive Cancer Center | Stanford | California | 94305 | United States | Details | |
| UF Health Cancer Center at Orlando Health | Orlando | Florida | 32824 | United States | Details | |
| Florida Cancer Specialist, North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| Massachusetts General Hospital;Hematology/ Oncology | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan; Michigan Institute for Clinical and Health Research (MICHR) | Ann Arbor | Michigan | 48109 | United States | Details | |
| Dartmouth-Hitchcock Medical Center; Hematology/Oncology | Lebanon | New Hampshire | 03756 | United States | Details | |
| Morristown Medical Center | Morristown | New Jersey | 07962 | United States | Details | |
| Forsythe Memorial Hospital Inc., dba Novant Health Oncology Specialists | Winston-Salem | North Carolina | 27103 | United States | Details | |
| TriHealth Hatton Institute; Surgical Education | Cincinnati | Ohio | 45220 | United States | Details | |
| St. Luke's University Health network | Bethlehem | Pennsylvania | 18015 | United States | Details | |
| Thomas Jefferson University Hospital;Medical Oncology | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| SCRI Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| M.D Anderson Cancer Center; Uni of Texas At Houston | Houston | Texas | 77030 | United States | Details | |
| West Virginia University Hospitals Inc | Morgantown | West Virginia | 26056 | United States | Details | |
| Cairns Base Hospital | Cairns | Queensland | 4870 | Australia | Details | |
| Townsville General Hospital | Douglas | Queensland | 4184 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Tasmania | 7000 | Australia | Details | |
| Fiona Stanley Hospital | Murdoch | Western Australia | 6150 | Australia | Details | |
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| AZ Groeninge | Kortrijk | 8500 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Instituto Nacional de Cancer - INCa; Oncologia | Rio de Janeiro | RJ | 20560-120 | Brazil | Details | |
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | 90035-903 | Brazil | Details | |
| Hopital Avicenne; Dermatologie | Bobigny | 93009 | France | Details | ||
| Hopital Saint Andre CHU De Bordeaux; Dermatologie | Bordeaux | 33075 | France | Details | ||
| Chu Site Du Bocage;Dermatologie | Dijon | 21079 | France | Details | ||
| CHU de Grenoble - Hôpital Nord | Grenoble | 38043 | France | Details | ||
| Centre Hospitalier Le Mans; Dermatologie | Le Mans | 72037 | France | Details | ||
| Hopital Claude Huriez; Sce Dermatologie | Lille | 59037 | France | Details | ||
| Hopital Timone Adultes; Dermatologie | Marseille | 13385 | France | Details | ||
| CHU de Nantes; Cancéro-dermatologie | Nantes | 44093 | France | Details | ||
| Hopital l Archet 2; Ginestriere, Service de; Dermatologie | Nice cedex 3 | 06200 | France | Details | ||
| Groupe Hospitalier Bichat Claude Bernard | Paris | 75018 | France | Details | ||
| Hopital Saint Louis; Dermatologie 1 | Paris | 75475 | France | Details | ||
| Hopital Robert Debre; DERMATOLOGIE | Reims | 51092 | France | Details | ||
| Centre Eugene Marquis; Service d'oncologie | Rennes | 35042 | France | Details | ||
| Hopital Charles Nicolle; Dermatologie Serv. | Rouen | 76031 | France | Details | ||
| Institut Universitaire du Cancer - Oncopole Toulouse (IUCT-O) | Toulouse | 31059 | France | Details | ||
| Institut Gustave Roussy; Dermatologie | Villejuif | 94805 | France | Details | ||
| Universitätsklinikum "Carl Gustav Carus"; Klinik und Poliklinik für Dermatologie | Dresden | 01307 | Germany | Details | ||
| HELIOS Klinikum Erfurt; Klinik für Dermatologie & Allergologie | Erfurt | 99089 | Germany | Details | ||
| Universitatsklinikum Essen; Klinik für Dermatologie | Essen | 45147 | Germany | Details | ||
| Klinik Johann Wolfgang von Goethe Uni; Klinik für Dermatologie, Venerologie und Allergologie | Frankfurt | 60590 | Germany | Details | ||
| SRH Wald-Klinikum Gera; Klinik für Hautkrankheiten und Allergologie | Gera | 07548 | Germany | Details | ||
| Medizinische Hochschule Hannover; Klinik für Dermatologie, Allergologie und Venerologie | Hannover | 30625 | Germany | Details | ||
| UKSH Kiel; Klinik für Dermatologie, Venerologie und Allergologie | Kiel | 24105 | Germany | Details | ||
| Universitatsklinikum Mainz; Klinik und Poliklinik fur Dermatologie | Mainz | 55131 | Germany | Details | ||
| Klinikum Mannheim Klinik fuer Dermatologie, Venerologie und Allergologie | Mannheim | 68167 | Germany | Details | ||
| Johannes Wesling Klinikum Minden; Hämatologie, Onkologie, Hämostaseologie und Palliativmedizin | Minden | 32429 | Germany | Details | ||
| Klinikum der Ludwigs-Maximilians-Universität München; Dermatologie | München | 80337 | Germany | Details | ||
| Fachklinik Hornheide; Dermatologie | Münster | 48157 | Germany | Details | ||
| Zentrum für Dermatoonkologie, Universitäts-Hautklinik Tübingen | Tübingen | 72076 | Germany | Details | ||
| Anticancer Hospital Ag. Savas ; 2Nd Dept. of Oncology - Internal Medicine | Athens | 115 22 | Greece | Details | ||
| Laiko General Hospital Athen | Athens | 115 27 | Greece | Details | ||
| Metropolitan Hospital; Dept. of Oncology | Pireaus | 185 47 | Greece | Details | ||
| Bioclinic Thessaloniki | Thessaloniki | 546 22 | Greece | Details | ||
| Orszagos Onkologiai Intezet; Borgyogyaszati Osztaly | Budapest | 1122 | Hungary | Details | ||
| Pecsi Tudomanyegyetem AOK; Borgyogyaszati Klinika | Pecs | 7632 | Hungary | Details | ||
| University of Szeged Szent-Györgyi Albert Clinical Center; Department of Dermatology and Allergology | Szeged | 6720 | Hungary | Details | ||
| Azienda Osp Uni Seconda Università Degli Studi Di Napoli; Unità Operativa Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| IRCCS Istituto Nazionale Tumori Fondazione Pascale; Oncologia Medica B | Napoli | Campania | 80131 | Italy | Details | |
| A.O. Universitaria Policlinico Di Modena; Ematologia | Modena | Emilia-Romagna | 41124 | Italy | Details | |
| IFO - Istituto Regina Elena; Oncologia Medica | Roma | Lazio | 00144 | Italy | Details | |
| IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A | Genova | Liguria | 16132 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 2 | Milano | Lombardia | 20133 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica | Milano | Lombardia | 20141 | Italy | Details | |
| Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico | Candiolo | Piemonte | 10060 | Italy | Details | |
| A.O.U. Cons. Policlinico Bari - Consorzlale Policlinico; Scienze Biomediche e Oncologia Umana | Bari | Puglia | 70124 | Italy | Details | |
| Azienda Ospedaliero - Universitaria Pisana U.O. Oncologia Medica 2 Universitaria - Polo Oncologico | Pisa | Toscana | 56126 | Italy | Details | |
| IOV - Istituto Oncologico Veneto IRCCS | Padova | Veneto | 35128 | Italy | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Antoni Van Leeuwenhoek Ziekenhuis; Inwendige Geneeskunde | Amsterdam | 1066 CX | Netherlands | Details | ||
| Amphia Ziekenhuis, locatie Langendijk;Oncology | Breda | 4818 CK | Netherlands | Details | ||
| Erasmus Mc - Daniel Den Hoed Kliniek; Interne Oncologie | Rotterdam | 3015AA | Netherlands | Details | ||
| Zuyderland ziekenhuis locatie Geleen | Sittard-Geleen | 6162 BG | Netherlands | Details | ||
| Copernicus Podmiot Medyczny Sp. z o.o. Wojewodzkie Centrum Onkologii | Gdansk | 80-219 | Poland | Details | ||
| COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej | Lublin | 20-090 | Poland | Details | ||
| Szpital Kliniczny im. Heliodora Święcickiego UM w Poznaniu. | Poznań | 60-780 | Poland | Details | ||
| Zachodniopomorskie Centrum Onkologii, Osrodek Innowacyjnosci, Rozwoju i Badan Klinicznych | Szczecin | 71-730 | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| Dolnośląskie Centrum Onkologii, Pulmonologii i Hematologii | Wrocław | 53-413 | Poland | Details | ||
| Moscow City Oncology Hospital #62 | Moscovskaya Oblast | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin" | Moscow | 115478 | Russian Federation | Details | ||
| FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov" | Saint-Petersburg | Russian Federation | Details | |||
| St. Petersburg Oncology Hospital | St Petersburg | 198255 | Russian Federation | Details | ||
| Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario Son Espases; Servicio de Oncologia | Palma De Mallorca | Islas Baleares | 07014 | Spain | Details | |
| Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia | Santiago de Compostela | LA Coruña | 15706 | Spain | Details | |
| Hospital Universitario Materno Infantil de Gran Canaria; Servicio de Oncologia | Las Palmas de Gran Canaria | LAS Palmas | 35016 | Spain | Details | |
| Clinica Universitaria de Navarra; Servicio de oncología | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic i Provincial; Servicio de Oncología | Barcelona | 08036 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | Madrid | 28007 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario La Paz; Servicio de Oncologia | Madrid | 28046 | Spain | Details | ||
| Hospital Universitario Virgen Macarena; Servicio de Oncologia | Sevilla | 41009 | Spain | Details | ||
| Instituto Valenciano Oncologia; Oncologia Medica | Valencia | 46009 | Spain | Details | ||
| Hospital General Universitario de Valencia; Servicio de oncologia | Valencia | 46014 | Spain | Details | ||
| Hospital Universitario Miguel Servet; Servicio Oncologia | Zaragoza | 50009 | Spain | Details | ||
| BRISTOL ONCOLOGY CENTRE; CLINICAL TRIALS UNIT; R & D department | Bristol | BS2 8HW | United Kingdom | Details | ||
| Western General Hospital; Edinburgh Cancer Center | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| Leicester Royal Infirmary; Dept. of Medical Oncology | Leicester | LE1 5WW | United Kingdom | Details | ||
| University College London Hospital | London | NW1 - 2PG | United Kingdom | Details | ||
| Guys & St Thomas Hospital; Department of Oncology | London | SE1 9RT | United Kingdom | Details | ||
| University Hospitals of North Midlands NHS Trust-Royal Stoke University Hospital | Stoke-On-Trent | ST4 6QG | United Kingdom | Details | ||
| Singleton Hospital; Pharmacy | Swansea | SA2 8QA | United Kingdom | Details | ||
| Royal Cornwall Hospital | Truro | TR1 3LQ | United Kingdom | Details |