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NCT ID | NCT03274492 |
Title | A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma (POLARIX) |
Acronym | POLARIX |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | Yes |
Sponsors | Hoffmann-La Roche |
Indications | |
Therapies | |
Age Groups: | adult | senior |
Covered Countries | USA | TUR | POL | NZL | ITA | GBR | FRA | ESP | DEU | CZE | CHE | CAN | BRA | BEL | AUT | AUS |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States | Details | |
Southern Cancer Center | Daphne | Alabama | 36526 | United States | Details | |
City of Hope | Duarte | California | 91010 | United States | Details | |
Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | United States | Details | |
Rocky Mountain Cancer Centers, LLP | Aurora | Colorado | 80012 | United States | Details | |
Georgetown University Medical Center | Washington | District of Columbia | 20007 | United States | Details | |
Florida Cancer Specialists - Fort Myers (New Hampshire Ct) | Fort Myers | Florida | 33901-8101 | United States | Details | |
Florida Cancer Specialists & Research Institute | Saint Petersburg | Florida | 33705 | United States | Details | |
Florida Cancer Specialists | West Palm Beach | Florida | 33401 | United States | Details | |
Emory University | Atlanta | Georgia | 30322 | United States | Details | |
Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | United States | Details | |
University of Louisville Hospital | Louisville | Kentucky | 40202 | United States | Details | |
Ochsner Medical Center | New Orleans | Louisiana | 70121 | United States | Details | |
University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
Johns Hopkins University | Baltimore | Maryland | 21287 | United States | Details | |
Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | United States | Details | |
University of Michigan Health System | Ann Arbor | Michigan | 48109 | United States | Details | |
Karmanos Cancer Center | Detroit | Michigan | 48201 | United States | Details | |
Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
Memorial Sloan Kettering Bergen | Montvale | New Jersey | 07645 | United States | Details | |
Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
Memorial Sloan Kettering Cancer Center - Commack | Commack | New York | 11725 | United States | Details | |
Memorial Sloan Kettering Cancer Center at Westchester | Harrison | New York | 10604 | United States | Details | |
New York University Cancer Cen | New York | New York | 10016 | United States | Details | |
Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
University of Rochester Medical Center | Rochester | New York | 14642 | United States | Details | |
University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | United States | Details | |
Levine Cancer Institute - Clincal Trials Administration | Charlotte | North Carolina | 28204 | United States | Details | |
Oncology/Hematology Care Clinical Trials LLC | Cincinnati | Ohio | 45236 | United States | Details | |
University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | United States | Details | |
Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
Oncology Associates of Oregon, P.C | Eugene | Oregon | 97401 | United States | Details | |
Northwest Cancer Specialists - Portland (SW Barnes Rd) | Portland | Oregon | 97225 | United States | Details | |
Oregon HSU | Portland | Oregon | 97239 | United States | Details | |
Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States | Details | |
Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
University of Pittsburgh Medical Center Cancer Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
Medical University of South Carolina Hospital | Charleston | South Carolina | 29425 | United States | Details | |
Prisma Health ? Upstate | Greenville | South Carolina | 29615 | United States | Details | |
Greco-Hainesworth Centers for Research | Chattanooga | Tennessee | 37403 | United States | Details | |
Tennessee Oncology - Nashville | Nashville | Tennessee | 37203 | United States | Details | |
Texas Oncology-Austin Midtown | Austin | Texas | 78705 | United States | Details | |
Texas Oncology San Antonio Medical Center | San Antonio | Texas | 78229 | United States | Details | |
Texas Oncology-Tyler | Tyler | Texas | 75702 | United States | Details | |
University of Utah | Salt Lake City | Utah | 84112 | United States | Details | |
Oncology Associates of Southwest Virginia, Inc. | Blacksburg | Virginia | 24060 | United States | Details | |
Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | United States | Details | |
Seattle Cancer Care Alliance | Seattle | Washington | 98101 | United States | Details | |
West Virginia Uni Med. Center - Robert Byrd Health Science | Morgantown | West Virginia | 26506 | United States | Details | |
Concord Repatriation General Hospital | Concord | New South Wales | 2139 | Australia | Details | |
St George Hospital | Kigarah | New South Wales | 2217 | Australia | Details | |
Prince of Wales Hospital | Randwick | New South Wales | 2031 | Australia | Details | |
Calvary Mater Newcastle | Waratah | New South Wales | 2298 | Australia | Details | |
Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
Princess Alexandra Hospital Woolloongabba | Woolloongabba | Queensland | 4102 | Australia | Details | |
Ashford Cancer Center Research | Kurralta Park | South Australia | 5037 | Australia | Details | |
The University of Adelaide - The Queen Elizabeth Hospital (TQEH) | Woodville South | South Australia | 5011 | Australia | Details | |
Monash Medical Centre | Clayton | Victoria | 3168 | Australia | Details | |
Austin Hospital | Heidelberg | Victoria | 3084 | Australia | Details | |
Paracelsus Medizinischen Privatuniversitaet-Salzburger Landeskliniken (SALK) | Salzburg | 5020 | Austria | Details | ||
Medizinische Universität Wien | Wien | 1090 | Austria | Details | ||
Wiener Gesundheitsverbund ? Klinik Ottakring | Wien | 1160 | Austria | Details | ||
UZ Gent | Gent | 9000 | Belgium | Details | ||
CH Jolimont - Lobbes (Jolimont) | Haine-Saint-Paul | 7100 | Belgium | Details | ||
CHU UCL Mont-Godinne | Mont-godinne | 5530 | Belgium | Details | ||
Hospital Erasto Gaertner | Curitiba | Paraná | 81520-060 | Brazil | Details | |
Hospital das Clinicas - UFRGS | Porto Alegre | Rio Grande Do Sul | Brazil | Details | ||
Centro de Hematologia e Hemoterapia - HEMOCENTRO UNICAMP | Campinas | São Paulo | 13083-878 | Brazil | Details | |
Hospital das Clinicas - FMUSP | Sao Paulo | São Paulo | 05403-000 | Brazil | Details | |
University of Alberta Hospital | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
BC Cancer ? Vancouver | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
CancerCare Manitoba (CCMB) | Winnipeg | Manitoba | MB R3E 0V9 | Canada | Details | |
The Ottawa Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
Sunnybrook Health Sciences Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
CIUSSS de l Est de l Ile de Montreal - Hopital Maisonneuve Rosemont | Montreal | Quebec | H1T 2M4 | Canada | Details | |
CHU de Quebec-Universite Laval | Quebec | G1J 1Z4 | Canada | Details | ||
Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
The First Hospital of Jilin University | Changchun City | 130021 | China | Details | ||
Fujian Provincial Cancer Hospital | Fuzhou City | 350014 | China | Details | ||
Sun Yet-sen University Cancer Center | Guangzhou | 510060 | China | Details | ||
The First Affiliated Hospital of College of Medicine, Zhejiang University | Hangzhou | 310003 | China | Details | ||
Jiangsu Cancer Hospital | Nanjing | 210009 | China | Details | ||
Ruijin Hospital, Shanghai Jiaotong University School of Medicine | Shanghai City | 200025 | China | Details | ||
Shanghai East Hospital, Tongji University | Shanghai City | 200032 | China | Details | ||
Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences | Tianjin City | 300020 | China | Details | ||
Tianjin Medical University Cancer Institute & Hospital | Tianjing | 300060 | China | Details | ||
Union Hospital Tongji Medical College Huazhong University of Science and Technology | Wuhan City | 430022 | China | Details | ||
Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
Fakultni Nemocnice Hradec Kralove (FNHK) | Hradec Kralove | 500 05 | Czechia | Details | ||
Fakultni nemocnice Olomouc | Olomouc | 775 20 | Czechia | Details | ||
Fakultni nemocnice Ostrava | Ostrava - Poruba | 708 52 | Czechia | Details | ||
Fakultni Nemocnice Kralovske Vinohrady (FNKV) | Prague | 100 34 | Czechia | Details | ||
Univerzita Karlova v Praze 1. Lekarska Fakulta | Prague | 128 08 | Czechia | Details | ||
CHU Amiens - Hopital Sud | Amiens | 80054 | France | Details | ||
CHU Angers | Angers | 49933 | France | Details | ||
Centre Hospitalier de La Cote Basque | Bayonne | 64109 | France | Details | ||
Hopital Jean Minjoz | Besancon | 25030 | France | Details | ||
Institut Bergonie | Bordeaux | 33076 | France | Details | ||
Institut d'Hématologie de Basse Normandie | Caen | 14000 | France | Details | ||
CH Metropole de Savoie | CHAMBERY Cedex | 73011 | France | Details | ||
Hopital Henri Mondor | Creteil | 94010 | France | Details | ||
CHU de Dijon - Hopital le Bocage | Dijon | 21000 | France | Details | ||
L'Union Mutualiste de la Gestion des Eaux Claires - Institut Daniel Hollard | Grenoble | 38000 | France | Details | ||
CHD Vendée | La Roche Sur Yon | 85025 | France | Details | ||
Hôpital Albert Michallon | La Tronche | 38700 | France | Details | ||
Clinique Victor Hugo - Centre Jean Bernard | Le Mans Cedex 02 | 72015 | France | Details | ||
Hôpital Saint Vincent de Paul | Lille | 59000 | France | Details | ||
Hopital Claude Huriez | Lille | 59037 | France | Details | ||
Hopital Uni Ire Dupuytren | Limoges | 87042 | France | Details | ||
Centre Leon Berard | Lyon | 69008 | France | Details | ||
CHU Montpellier - Saint ELOI | Montpellier | 34295 | France | Details | ||
CHU de Nantes - Hotel Dieu | Nantes | 44093 | France | Details | ||
Centre Antoine Lacassagne | Nice | 06189 | France | Details | ||
CHU de Nîmes - Hôpital Carémeau | Nimes | 30029 | France | Details | ||
Hôpital Saint-Louis | Paris | 75475 | France | Details | ||
Gh Necker Enfants Malades | Paris | 75743 | France | Details | ||
Hopital Saint Jean | Perpignan | 66046 | France | Details | ||
Hopital Haut-Leveque - Centre Francois Magendie | Pessac | 33604 | France | Details | ||
CHU Lyon Sud - Service Hématologie | Pierre Benite | 69310 | France | Details | ||
CHU de Poitiers | Poitiers | 86021 | France | Details | ||
Centre Hospitalier de Quimper Cornouaille (CHIC) | Quimper Cedex | 29107 | France | Details | ||
Hopital Pontchaillou | Rennes | 35033 | France | Details | ||
Centre Henri Becquerel | Rouen | 76038 | France | Details | ||
Centre Hospitalier de Saint Brieuc - Hôpital Yves Le Foll | St Brieuc | 22027 | France | Details | ||
Pôle de Cancérologie ? CHU de Saint?Etienne' | St Priest en Jarez | 42270 | France | Details | ||
Chru de Strasbourg | Strasbourg | 67091 | France | Details | ||
Institut Universitaire du Cancer - Oncopole Toulouse (IUCT-O) | Toulouse | 31059 | France | Details | ||
CHU Bretonneau | Tours | 37044 | France | Details | ||
CHU de Brabois | Vandoeuvre Les Nancy | 54511 | France | Details | ||
CH Bretagne Atlantique | Vannes Cedex | 56017 | France | Details | ||
Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
Vivantes Klinikum Am Urban | Berlin | 10967 | Germany | Details | ||
Städtisches Klinikum Dessau | Dessau-Roßlau | 06847 | Germany | Details | ||
Universitätsklinikum Essen | Essen | 45147 | Germany | Details | ||
Universitaetsklinikum Halle (Saale) | Halle | 06120 | Germany | Details | ||
Universitaetsklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
InVO - Institut für Versorgungsforschung in der Onkologie GbR | Koblenz | 56068 | Germany | Details | ||
Universitatsklinikum Munster | Münster | 48149 | Germany | Details | ||
Azienda Ospedaliera Papa Giovanni XXIII | Bergamo | Abruzzo | 24060 | Italy | Details | |
Universita degli Studi Di Brescia - Azienda Ospedaliera Spedali Civili di Brescia | Brescia | Abruzzo | Italy | Details | ||
Universita degli Studi di Roma ''La Sapienza" - Clinica Ematologica | Rome | Abruzzo | Italy | Details | ||
AUSL di Reggio Emilia, IRCCS, P.O. Arcispedale Santa Maria Nuova | Reggio Emilia | Emilia-Romagna | Italy | Details | ||
IRCCS AOU San Martino - IST | Genova | Liguria | 16132 | Italy | Details | |
Istituto Nazionale dei Tumori | Monza | Lombardia | 20052 | Italy | Details | |
Azienda Ospedaliero Universitaria Maggiore della Carita di Novara | Novara | Piemonte | 28100 | Italy | Details | |
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino | Torino | Piemonte | 00126 | Italy | Details | |
Aichi Cancer Center | Aichi | 464-8681 | Japan | Details | ||
Chiba Cancer Center | Chiba | 260-8717 | Japan | Details | ||
National Cancer Center Hospital East | Chiba | 277-8577 | Japan | Details | ||
Chiba University Hospital | Chuo-ku | 260-8670 | Japan | Details | ||
National Hospital Organization Kyushu Cancer Center | Fukuoka | 811-1395 | Japan | Details | ||
Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
Hokkaido University Hospital | Hokkaido | 060-8648 | Japan | Details | ||
Kobe City Medical Center General Hospital | Hyogo | 650-0047 | Japan | Details | ||
Tokai University Hospital | Isehara-shi | 259-1193 | Japan | Details | ||
Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
University Hospital Kyoto Prefectural University of Medicine | Kyoto | 602-8566 | Japan | Details | ||
Tohoku University Hospital | Miyagi | 980-8574 | Japan | Details | ||
Osaka Metropolitan University Hospital | Osaka | 545-8586 | Japan | Details | ||
Osaka University Hospital | Osaka | 565-0871 | Japan | Details | ||
Kindai University Hospital | Osaka | 589-8511 | Japan | Details | ||
Jichi Medical University Hospital | Tochigi | 329-0498 | Japan | Details | ||
National Cancer Center Hospital | Tokyo | 104-0045 | Japan | Details | ||
The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
Pusan National University Hospital | Busan | 49241 | Korea, Republic of | Details | ||
National Cancer Center | Gyeonggi-do | 410-769 | Korea, Republic of | Details | ||
Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
Severance Hospital | Seoul | 03722 | Korea, Republic of | Details | ||
Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
Pusan National University Yangsan Hospital | Yangsan | Korea, Republic of | Details | |||
Auckland City Hospital, Cancer and Blood Research | Auckland | 1023 | New Zealand | Details | ||
Canterbury Health Laboratories | Christchurch | 8140 | New Zealand | Details | ||
Waikato Hospital | Hamilton | 3240 | New Zealand | Details | ||
Wojewódzki Szpital Specjalistyczny im. M. Kopernika | ?ód? | 93-510 | Poland | Details | ||
Samodzielny Publiczny Zak?ad Opieki Zdrowotnej Zespó? Szpitali Miejskich w Chorzowie | Chorzów | 41-500 | Poland | Details | ||
PRATIA MCM Kraków | Kraków | 30-727 | Poland | Details | ||
SPZOZ Ministerstwa Spraw Wewn?trznych i Administracji w Poznaniu | Pozna? | 60-631 | Poland | Details | ||
Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy | Warszawa | 04-141 | Poland | Details | ||
Leningrad Regional Clinical Hospital | St Petersburg | Sankt Petersburg | 194291 | Russian Federation | Details | |
Complejo Hospitalario de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
Hospital Clinic Barcelona | Barcelona | 08036 | Spain | Details | ||
Hospital de la Santa Creu i Sant Pau | Barcelona | 08041 | Spain | Details | ||
Institut Catala d Oncologia Hospitalet | Barcelona | 08908 | Spain | Details | ||
Hospital San Pedro de Alcantara | Caceres | 10003 | Spain | Details | ||
Hospital Universitari Dr. Josep Trueta | Girona | 17007 | Spain | Details | ||
Hospital Universitario La Paz | Madrid | 280146 | Spain | Details | ||
Fundación Jimenez Díaz | Madrid | 28040 | Spain | Details | ||
Hospital Quiron Madrid | Madrid | 28233 | Spain | Details | ||
Hospital Universitario Virgen de la Victoria | Malaga | 29010 | Spain | Details | ||
Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
Universitätsspital Basel Gynäkologie - Onkologie | Basel | 4031 | Switzerland | Details | ||
Kaohsiung Medical University Hospital, Cancer Center | Kaohsiung | 807 | Taiwan | Details | ||
China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
Chi-Mei Hospital, Liouying | Tainan | 736 | Taiwan | Details | ||
National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
Taipei Veterans General Hospital | Taipei | 11211 | Taiwan | Details | ||
Ankara University Faculty of Medicine Cebeci Hospital | Ankara | 06700 | Turkey | Details | ||
Ege Üniversitesi Tip Fakültesi | Lzmir | 35100 | Turkey | Details | ||
Dokuz Eylul Universitesi Tip Fakultesi | Lzmir | 35340 | Turkey | Details | ||
Communal Institution 'Cherkassy Regional Oncology Dispensary' of the Cherkassy Regional Council | Cherkassy | Chernihiv Governorate | Ukraine | Details | ||
MNE Lviv Territorial Medical Association Clinical Hospital for Palliative Care | Lviv | Chernihiv Governorate | 79007 | Ukraine | Details | |
Khmelnytskyi Regional Hospital | Khmelnytskyi | Kharkiv Governorate | 29000 | Ukraine | Details | |
Feofaniya Center of Haematology and Chemotherapy of Haemoblastosis | Kyiv | Volhynian Governorate | 03143 | Ukraine | Details | |
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital | Cambridge | CB2 0QQ | United Kingdom | Details | ||
East Kent Hospitals University NHS Foundation Trust | Canterbury | CT1 3NG | United Kingdom | Details | ||
University Hospitals of Leicester NHS Trust - Leicester Royal Infirmary | Leicester | LE1 5WW | United Kingdom | Details | ||
Barts Health NHS Trust | London | EC1A 7BE | United Kingdom | Details | ||
The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
The Newcastle upon Tyne Hospitals NHS Foundation Trust. Freeman Hospital | Newcastle upon Tyne | NE7 7DN | United Kingdom | Details | ||
Nottingham City Hospital | Nottingham | NG5 1PB | United Kingdom | Details | ||
Oxford University Hospitals NHS Foundation Trust | Oxford | OX3 7LE | United Kingdom | Details |