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| NCT ID | NCT03301220 |
| Title | A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Janssen Research & Development, LLC |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | SWE | POL | NOR | NLD | ITA | ISR | HUN | GRC | GBR | FRA | ESP | DNK | DEU | CZE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Arizona Oncology Associates, PC - HAL | Phoenix | Arizona | 85016 | United States | Details | |
| Innovative Clinical Research Inc | Whittier | California | 90805 | United States | Details | |
| Miami Cancer Institute | Miami | Florida | 33176 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215-5418 | United States | Details | |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
| VA Southern Nevada Healthcare | North Las Vegas | Nevada | 89086 | United States | Details | |
| New York Oncology Hematology | Albany | New York | 12206 | United States | Details | |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | United States | Details | |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | United States | Details | |
| Levine Cancer Institute, Carolinas HealthCare System | Charlotte | North Carolina | 28204 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| The Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
| OHSU/CHM | Portland | Oregon | 97239 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Texas Oncology P A | Austin | Texas | 78705 | United States | Details | |
| VA North Texas Health Care System | Dallas | Texas | 75216 | United States | Details | |
| Texas Oncology P A | Tyler | Texas | 75702 | United States | Details | |
| University of Washington | Seattle | Washington | 90805 | United States | Details | |
| Hospital Aleman | Buenos Aires | C1118AAT | Argentina | Details | ||
| Hospital Italiano de Buenos Aires | Buenos Aires | C1199ABD | Argentina | Details | ||
| CEMIC Saavedra | Ciudad de Buenos Aires | 1431 | Argentina | Details | ||
| Hospital Privado - Centro Medico de Cordoba | Cordoba | X5016KEH | Argentina | Details | ||
| Hospital Italiano de La Plata | La Plata | B1900AXI | Argentina | Details | ||
| Sanatorio Britanico de Rosario | Rosario | 2000 | Argentina | Details | ||
| Austin Hospital | Heidelberg | 3150 or 3084 | Australia | Details | ||
| Calvary Mater Newcastle Hospital | Waratah | 2298 | Australia | Details | ||
| The Perth Blood Institute | West Perth | 6005 | Australia | Details | ||
| Queen Elizabeth Hospital | Woodville | 5011 | Australia | Details | ||
| ZNA | Antwerpen | 2060 | Belgium | Details | ||
| AZ St.-Jan Brugge-Oostende AV | Brugge | 8000 | Belgium | Details | ||
| UZBrussel | Brussel | 1090 | Belgium | Details | ||
| UZ Gent | Gent | 9000 | Belgium | Details | ||
| Virga Jessa Ziekenhuis | Hasselt | 3500 | Belgium | Details | ||
| Az Groeninge | Kortrijk | 8500 | Belgium | Details | ||
| Centro de Pesquisa e Ensino em Oncologia de Santa Catarina CEPEN | Florianopolis | 88034-000 | Brazil | Details | ||
| Universidade Federal de Goias - Hospital das Clinicas da UFG | Goiania | 74605-020 | Brazil | Details | ||
| Instituto Joinvilense de Hematologia e Oncologia Ltda Centro de Hematologia e Oncologia | Joinville | 89201-260 | Brazil | Details | ||
| Hospital das Clinicas de Porto Alegre | Porto Alegre | 90035-003 | Brazil | Details | ||
| Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI) | Rio de Janeiro | 22775 001 | Brazil | Details | ||
| Hospital Sao Rafael | Salvador | 41235-190 | Brazil | Details | ||
| Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base | Sao Jose do Rio Preto | 15090-000 | Brazil | Details | ||
| Instituto de Ensino e Pesquisa São Lucas | Sao Paulo | 01236-030 | Brazil | Details | ||
| Clinica Sao Germano | São Paulo | 01455 010 | Brazil | Details | ||
| Hospital Santa Cruz | São Paulo | 04122-000 | Brazil | Details | ||
| Arthur J. E. Child Comprehensive Cancer Centre | Calgary | Alberta | T2N 5G2 | Canada | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Lakeridge Health Oshawa | Oshawa | Ontario | L1G-2B9 | Canada | Details | |
| Fakultni nemocnice Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
| Fakultni Nemocnice Ostrava | Ostrava | 70852 | Czechia | Details | ||
| Fakultni nemocnice Plzen, Hemato-onkologicke oddeleni | Plzen | 323 00 | Czechia | Details | ||
| Vseobecna fakultni nemocnice v Praze - I. interni klinika - klinika hematologie | Praha 2 | 128 08 | Czechia | Details | ||
| Aarhus University Hospital | Aarhus N. | 8200 | Denmark | Details | ||
| Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
| Odense Universitetshospital | Odense C | 5000 | Denmark | Details | ||
| Ålborg Universitetshospital | Ålborg | 9000 | Denmark | Details | ||
| CHU de Limoges - Fédération Hépatologie | Limoges | 87000 | France | Details | ||
| Chu Hotel Dieu | Nantes cedex 01 | 44035 | France | Details | ||
| CHU de Bordeaux - Hospital Haut-Leveque | Pessac cedex | 33604 | France | Details | ||
| Centre hospitalier Lyon-Sud | Pierre Benite cedex | 69495 | France | Details | ||
| CHU De Poitiers | Poitiers | 86021 | France | Details | ||
| l'Hôpital Pontchaillou | Rennes | 35033 | France | Details | ||
| CHU Bretonneau | Tours Cedex 9 | 37044 | France | Details | ||
| Helios Kliniken Berlin Buch Gmbh | Berlin | 13125 | Germany | Details | ||
| St. Barbara-Klinik Hamm GmbH | Hamm | 59073 | Germany | Details | ||
| Universitaetsklinikum Heidelberg Medizinische Klinik V | Heidelberg | 69120 | Germany | Details | ||
| Medizinische Klinik A | Muenster | 48149 | Germany | Details | ||
| Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II, | Tübingen | 72076 | Germany | Details | ||
| Universitaetsklinikum Ulm | Ulm | 89081 | Germany | Details | ||
| Alexandra General Hospital of Athens | Athens Attica | 115 28 | Greece | Details | ||
| Semmelweis Egyetem, I. Belgyogyaszati Klinika | Budapest N/a | 1083 | Hungary | Details | ||
| Semmelweis Egyetem I.Belgyogyaszati Klinika | Budapest | 1088 | Hungary | Details | ||
| Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely | Budapest | 1097 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Kozpont | Debrecen | 4032 | Hungary | Details | ||
| Haemek | Afula | 18101 | Israel | Details | ||
| Barzilai Medical Center | Ashkelon | 78741 | Israel | Details | ||
| Bnai Zion Medical Center | Haifa | 31048 | Israel | Details | ||
| Carmel Medical Center | Haifa | 3436212 | Israel | Details | ||
| Rambam Medical Center | Haifa | 3525408 | Israel | Details | ||
| Hadassah Medical Center | Jerusalem | 9112001 | Israel | Details | ||
| Galilee Medical Center | Nahariya | 22100 | Israel | Details | ||
| Rabin Medical Center | Petah-Tiqva | 49100 | Israel | Details | ||
| Sheba Medical Center | Ramat Gan | 52621 | Israel | Details | ||
| Sourasky Medical Center | Tel-Aviv | 6423906 | Israel | Details | ||
| Policlinico Sant'Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Businco Cancer Hospital | Cagliari | 09121 | Italy | Details | ||
| A.O. Santa Croce e Carle | Cuneo | 12100 | Italy | Details | ||
| Ospedale S. Eugenio | Roma | 00144 | Italy | Details | ||
| Università di Roma 'La Sapienza' - Ospedale Umberto 1° | Roma | 00161 | Italy | Details | ||
| A.O.U. Città della Salute e della Scienza di Torino- Divisione di Ematologia | Torino | 10126 | Italy | Details | ||
| ASST dei Sette Laghi, Ospedale di Circolo e Fonazione Macchi | Varese | 21100 | Italy | Details | ||
| Fukuoka University Hospital | Fukuoka | 814-0180 | Japan | Details | ||
| Chugoku Central Hospital | Fukuyama | 720-0001 | Japan | Details | ||
| Ogaki Municipal Hospital | Gifu | 503-8502 | Japan | Details | ||
| Kagoshima University Hospital | Kagoshima | 890-8520 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
| National Hospital Organization Osaka Minami Medical Center | Kawachi Nagano | 586 8521 | Japan | Details | ||
| Kobe City Medical Center General Hospital | Kobe City | 650 0047 | Japan | Details | ||
| National Hospital Organization Kumamoto Medical Center | Kumamoto-shi | 860-0008 | Japan | Details | ||
| Kurume University Hospital | Kurume | 830-0011 | Japan | Details | ||
| Kyoto Kuramaguchi Medical Center | Kyoto | 603-8151 | Japan | Details | ||
| National Hospital Organization Matsumoto Medical Center | Matsumoto | 399-8701 | Japan | Details | ||
| Matsuyama Red Cross Hospital | Matsuyama | 790-8524 | Japan | Details | ||
| Nagoya City University Hospital | Nagoya | 467 8602 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| National Hospital Organization Okayama Medical Center | Okayama | 701-1192 | Japan | Details | ||
| National Hospital Organization Sendai Medical Center | Sendai-City | 983-8520 | Japan | Details | ||
| National Hospital Organization Shibukawa Medical Center | Shibukawa | 377-0280 | Japan | Details | ||
| Japanese Red Cross Medical Center | Shibuya | 150-8935 | Japan | Details | ||
| iBiomed Research Unit | Aguascalientes | 20121 | Mexico | Details | ||
| JM Research, SC | Cuernavaca | 62290 | Mexico | Details | ||
| Centro de Investigación Farmacéutica Especializada | Guadalajara | 44160 | Mexico | Details | ||
| Centro de Atención e Investigación Clínica en Oncología | Merida | 97134 | Mexico | Details | ||
| Hospital Universitario de Nuevo León | Monterrey | 64460 | Mexico | Details | ||
| Gelre Ziekenhuis | Apeldoorn | 7334 DZ | Netherlands | Details | ||
| Haga ziekenhuis | Den Haag | 2545 AA | Netherlands | Details | ||
| Albert Schweitzer Ziekenhuis | Dordrecht | 3318 AT | Netherlands | Details | ||
| ETZ TweeSteden | Tilburg | 5042 AD | Netherlands | Details | ||
| Oslo University Hospital HF Ulleval sykehus | Oslo | 0450 | Norway | Details | ||
| Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza | Brzozow | 36-200 | Poland | Details | ||
| Szpital Uniwersytecki nr 2 im. Jana Biziela w Bydgoszczy | Bydgoszcz | 85-168 | Poland | Details | ||
| Wojewodzki Szpital Specjalistyczny w Legnicy | Legnica | 59-220 | Poland | Details | ||
| Clinical Research Center Sp z o o Medic R Sp k | Poznan | 61-731 | Poland | Details | ||
| Instytut Hematologii i Transfuzjologii | Warszawa | 02-776 | Poland | Details | ||
| Emergency Hospital of Dzerzhinsk | Dzerzhinsk | 606019 | Russian Federation | Details | ||
| City clinical hospital n.a. S.P.Botkin | Moscow | 125284 | Russian Federation | Details | ||
| City Clinical Hospital # 40 | Moscow | 129301 | Russian Federation | Details | ||
| Nizhniy Novgorod Region Clinical Hospital | Nizhny Novgorod | 603126 | Russian Federation | Details | ||
| Perm Medical Sanitary Unit#1 | Perm | 614078 | Russian Federation | Details | ||
| Republican Hospital n.a.V.A.Baranov | Petrozavodsk | 185019 | Russian Federation | Details | ||
| Ryazan Regional Clinical Hospital | Ryazan | 390003 | Russian Federation | Details | ||
| Clinical Research Institute of Hematology and Transfusiology | St-Petersburg | 191024 | Russian Federation | Details | ||
| Oncology Dispensary of Komi Republic | Syktyvkar | 167904 | Russian Federation | Details | ||
| Hosp. Univ. Germans Trias I Pujol | Badalona | 08916 | Spain | Details | ||
| Hosp Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hosp Univ Vall D Hebron | Barcelona | 8035 | Spain | Details | ||
| Hosp. Gral. Univ. Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Hosp. Univ. Infanta Leonor | Madrid | 28031 | Spain | Details | ||
| Hosp. Univ. Ramon Y Cajal | Madrid | 28034 | Spain | Details | ||
| Clinica Univ. de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hosp. Quiron Madrid Pozuelo | Pozuelo De Alarcon, Madrid | 28223 | Spain | Details | ||
| Hosp Clinico Univ de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hosp. Univ. Dr. Peset | Valencia | 46017 | Spain | Details | ||
| Falu Lasarett | Falun | 79182 | Sweden | Details | ||
| Sunderby Sjukhus Medicinkliniken | Luelå | 97180 | Sweden | Details | ||
| Karolinska Universitetssjukhuset Huddinge | Stockholm | 141 86 | Sweden | Details | ||
| Ankara Numune Egitim ve Arastirma Hastanesi | Ankara | 06230 | Turkey | Details | ||
| Ankara University Medical Faculty | Ankara | 6100 | Turkey | Details | ||
| Trakya University Hospital | Edirne | 22030 | Turkey | Details | ||
| Istanbul University Istanbul Medical Faculty | Istanbul | 34093 | Turkey | Details | ||
| Erciyes University Medical Faculty | Kayseri | 38030 | Turkey | Details | ||
| Ondokuz Mayis University | Samsun | 55139 | Turkey | Details | ||
| Heart of England NHS Foundation Trust | Birmingham | B9 5SS | United Kingdom | Details | ||
| University Hospitals Bristol NHS Trust | Bristol | BS2 8ED | United Kingdom | Details | ||
| Kent and Canterbury Hospital | Canterbury | CT1 3NG | United Kingdom | Details | ||
| St Bartholomew's Hospital | London | EC1A 7BE | United Kingdom | Details | ||
| Christie Hospital NHS Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Nottingham University Hospitals NHS Trust | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Royal Stoke University Hospital | Stoke-On-Trent | ST4 6QG | United Kingdom | Details |