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| NCT ID | NCT03322566 |
| Title | A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Incyte Corporation |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | ITA | ISR | IRL | HUN | GBR | ESP | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Southern Cancer Center, PC | Daphne | Alabama | 36526 | United States | Details | |
| Western Regional Medical Center, Inc. | Goodyear | Arizona | 85338 | United States | Details | |
| Arizona Oncology Associates PC- HOPE | Tucson | Arizona | 85704 | United States | Details | |
| Lynn Cancer Institute | Boca Raton | Florida | 33486 | United States | Details | |
| Florida Cancer Specialists (South Region) | Fort Myers | Florida | 33901-8101 | United States | Details | |
| Florida Cancer Specialists (North Region) | Saint Petersburg | Florida | 33705 | United States | Details | |
| PPG-Oncology | Fort Wayne | Indiana | 46845 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109 | United States | Details | |
| MMCORC | Saint Louis Park | Minnesota | 55416 | United States | Details | |
| St. Vincent Healthcare Frontier Cancer Center | Billings | Montana | 59102 | United States | Details | |
| New York Oncology Hematology P.C | Albany | New York | 12208 | United States | Details | |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45242 | United States | Details | |
| Southwestern Regional Medical Center, Inc. | Tulsa | Oklahoma | 74133 | United States | Details | |
| St. Luke's Hospital - Anderson Campus | Easton | Pennsylvania | 18045 | United States | Details | |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| Tennessee Oncology, PLLC/The Sarah Cannon Research Institute | Chattanooga | Tennessee | 37404 | United States | Details | |
| Tennessee Oncology, PLLC/The Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Texas Oncology-Denton South | Denton | Texas | 76210 | United States | Details | |
| Oncology & Hematology Assoc. SW Virginia, Inc., DBA Blue Ridge Cancer Care | Blacksburg | Virginia | 24060 | United States | Details | |
| Emily Couric Clinical Cancer Center | Charlottesville | Virginia | 22908 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| MNCCI Port Macquarie Base Hospital | Port Macquarie | New South Wales (Australia) | 2444 | Australia | Details | |
| Blacktown Hospital | Blacktown | New South Wales | 2148 | Australia | Details | |
| Chris OBrien Lifehouse | Camperdown | New South Wales | 2050 | Australia | Details | |
| The Crown Princess Mary Cancer Centre Westmead | Westmead | New South Wales | 2145 | Australia | Details | |
| Southern Medical Day Care Centre | Wollongong | New South Wales | 2500 | Australia | Details | |
| Cairns Base Hospital | Cairns | Queensland | 4870 | Australia | Details | |
| BCCA-Cancer Centre of the Southern Interior | Kelowna | British Columbia | V1Y 5L3 | Canada | Details | |
| Lions Gate Hospital | North Vancouver | British Columbia | V7L 2L7 | Canada | Details | |
| CISSS de la Monteregie-Centre | Greenfield Park | Quebec | J4V 2H1 | Canada | Details | |
| CSSS de Laval- Hopital de la Cite de la Sante | Laval | Quebec | H7M 3L9 | Canada | Details | |
| CIUSSS Ouest de l'Ile - St-Mary's Hospital | Montréal | Quebec | H3T 1M5 | Canada | Details | |
| CIUSSS du Nord-de-l'ILe-de-Montreal Hopital du Sacre-Coeur de Montreal | Montréal | Quebec | H4J 1C5 | Canada | Details | |
| CIUSSS de la Mauricie-et-du-Centre-du-Quebec | Trois-Rivières | Quebec | G8Z 3R9 | Canada | Details | |
| CHU de Quebec - Hotel-Dieu de Quebec | Quebec | G1R 2J6 | Canada | Details | ||
| Zala Megyei Korhaz Pozvai Telephely | Pozva | Zalaegerszeg | 8900 | Hungary | Details | |
| Orszagos Koranyi TBC es Pulmonologiai Intezet | Budapest | 1121 | Hungary | Details | ||
| Veszprem Megyei Tudogyogyintezet | Farkasgyepű | 8582 | Hungary | Details | ||
| Bekes Megyei Pandy Kalman Korhaz | Gyula | 5700 | Hungary | Details | ||
| CRU Hungary Kft. | Miskolc | 3529 | Hungary | Details | ||
| Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet | Szolnok | 5004 | Hungary | Details | ||
| St Vincents University Hospital | Dublin | Dublin 4 | Ireland | Details | ||
| Ha Emek Medical Center | Afula | 1834111 | Israel | Details | ||
| Soroka Medical Center | Be'er Sheva | 8457108 | Israel | Details | ||
| Rambam Medical Center | Haifa | 3525408 | Israel | Details | ||
| Meir Medical Center | Kfar Saba | 4428164 | Israel | Details | ||
| Rabin Medical Center | Petah Tikva | 5262000 | Israel | Details | ||
| Chaim Sheba Medcal Center | Ramat Gan | 52621 | Israel | Details | ||
| Centro Di Riferimento Oncologico | Aviano | 33081 | Italy | Details | ||
| A.O.U. Policlinico Vittorio Emanuele - Presidio Gaspare Rodolico | Catania | 95123 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| Ospedale San Gerardo - ASST Monza | Monza | 20900 | Italy | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Medical Care Research S.A. de C.V. | Mérida | Yucatan | 97070 | Mexico | Details | |
| Oaxaca Site Management Organization S.C. | Oaxaca | 68000 | Mexico | Details | ||
| FAICIC Clinical Research | Veracruz | 91900 | Mexico | Details | ||
| Belgorod Regional Oncology Dispensary | Belgorod | 308010 | Russian Federation | Details | ||
| Udmurtia Republic Regional Clinical Oncology Dispensary | Izhevsk | 426067 | Russian Federation | Details | ||
| Republican Clinical Oncology Dispensary of Tatarstan MoH | Kazan | 420029 | Russian Federation | Details | ||
| Central Clinical Hospital with polyclinic | Moscow | 121359 | Russian Federation | Details | ||
| Moscow Research Oncology Institute | Moscow | 125284 | Russian Federation | Details | ||
| SBI of Stavropol region Pyatigorskiy Oncologic dispensary | Pyatigorsk | 357502 | Russian Federation | Details | ||
| SBHI Leningrad Regional Clinical Hospital | Saint Petersburg | 194291 | Russian Federation | Details | ||
| SBHI Samara Regional Clinical Oncology Dispensary | Samara | 443031 | Russian Federation | Details | ||
| Oncological Dispensary #2 of Ministry of Health of Krasnodar region | Sochi | 354057 | Russian Federation | Details | ||
| Tomsk Scientific Research Institute of Oncology | Tomsk | 634028 | Russian Federation | Details | ||
| Hospital Universitario Insular de Gran Canaria | Las Palmas De Gran Canaria | Gran Canaria | 35016 | Spain | Details | |
| Hospital Juan Ramón Jimenez | Huelva | 21005 | Spain | Details | ||
| Institut Catala Oncologia de Bellvitge - ICO | L'Hospitalet De Llobregat | 08980 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Universitario La Fe | Valencia | 46026 | Spain | Details | ||
| Hospital Clinico Universitario Lozano Blesa | Zaragoza | 50009 | Spain | Details | ||
| Chang Gung Medical Foundation, Kaohsiung Branch | Kaohsiung | 833 | Taiwan | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70457 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10048 | Taiwan | Details | ||
| Chang Gung Medical Foundation, Linkou Branch | Taoyuan | 33305 | Taiwan | Details | ||
| Ege Universitesi Tip Fakultesi Hastanesi | İzmir | Bornova | 35100 | Turkey | Details | |
| Baskent Universitesi Adana Uygulama ve Arastirma Hastanesi | Adana | 01120 | Turkey | Details | ||
| Cukurova Universitesi Tıp Fakultesi Balcalı Hastanesi | Adana | 01330 | Turkey | Details | ||
| Hacettepe Universitesi Tip Fakultesi Hastanesi | Ankara | 06100 | Turkey | Details | ||
| Uludag Universitesi Tip Fakultesi | Bursa | 16059 | Turkey | Details | ||
| Pamukkale Unv. Tip Fak | Denizli | 20070 | Turkey | Details | ||
| Istanbul Universitesi Cerrahpasa Tip Fakultesi | Istanbul | 34098 | Turkey | Details | ||
| Samsun Medical Park Hastanesi | Samsun | 55200 | Turkey | Details | ||
| Namık Kemal University Medical Faculty | Tekirdağ | 59030 | Turkey | Details | ||
| Mount Vernon Cancer Centre | Northwood | Middlesex | HA6 2RN | United Kingdom | Details | |
| Western General Hospital | Edinburgh | EH42XU | United Kingdom | Details | ||
| North Middlesex Hospital | London | N18 1QX | United Kingdom | Details | ||
| Freeman Hospital Newcastle upon Tyne Foundation NHS Trust | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details |