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| NCT ID | NCT03336333 |
| Title | A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL (SEQUOIA) |
| Acronym | SEQUOIA |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | BeiGene |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | SWE | POL | NZL | ITA | GBR | FRA | ESP | CZE | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Augusta University | Augusta | Georgia | 30912 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Research Medical Center | Kansas City | Missouri | 64132 | United States | Details | |
| Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | United States | Details | |
| Summit Medical Group | Florham Park | New Jersey | 07932 | United States | Details | |
| Icahn School of Medicine At Mount Sinai | New York | New York | 10029 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| Duke University | Durham | North Carolina | 27710 | United States | Details | |
| Oregon Health and Science University | Portland | Oregon | 97239 | United States | Details | |
| Prairie Lakes Healthcare System | Watertown | South Dakota | 57201 | United States | Details | |
| Tennessee Oncology, Pllc Nashville | Nashville | Tennessee | 37203 | United States | Details | |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22903 | United States | Details | |
| Va Puget Sound Health Care System | Seattle | Washington | 98108 | United States | Details | |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | United States | Details | |
| Concord Repatriation General Hospital | Concord | New South Wales | 2139 | Australia | Details | |
| The Tweed Valley Hospital | Cudgen | New South Wales | 2487 | Australia | Details | |
| Calvary Mater Newcastle | Waratah | New South Wales | 2298 | Australia | Details | |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
| Icon Cancer Centre Wesley | Auchenflower | Queensland | 4066 | Australia | Details | |
| Princess Alexandra Hospital | Brisbane | Queensland | 4102 | Australia | Details | |
| Royal Brisbane and Womens Hospital | Herston | Queensland | 4029 | Australia | Details | |
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia | Details | |
| The Queen Elizabeth Hospital | Woodville South | South Australia | 5011 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Tasmania | 7000 | Australia | Details | |
| Box Hill Hospital | Box Hill | Victoria | 3128 | Australia | Details | |
| Monash Health | Clayton | Victoria | 3168 | Australia | Details | |
| St Vincents Hospital Melbourne | Fitzroy | Victoria | 3065 | Australia | Details | |
| Peninsula Private Hospital | Frankston | Victoria | 3199 | Australia | Details | |
| Peter Maccallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| Royal Perth Hospital | Perth | Western Australia | 6000 | Australia | Details | |
| Medizinische Universitatsklinik Innsbruck | Innsbruck | 6020 | Austria | Details | ||
| Krankenhaus Der Barmherzigen Schwestern Linz | Linz | 4010 | Austria | Details | ||
| Allgemeines Krankenhaus Der Stadt Linz | Linz | 4021 | Austria | Details | ||
| Universitatsklinik Fur Innere Medizin Iii Universitatsklinikum Der Pmu Landeskrankenhaus Salzburg | Salzburg | 5020 | Austria | Details | ||
| Klinikum Wels Grieskirchen | Wels | 4600 | Austria | Details | ||
| Universitair Ziekenhuis Brussel | Brussels | 1090 | Belgium | Details | ||
| Universitair Ziekenhuis Gent | Gent | 9000 | Belgium | Details | ||
| Centre Hospitalier Universitaire (Chu) de Liege Site Du Sart Tilman | Liege | 4000 | Belgium | Details | ||
| Clinique Saint Pierre | Ottignies | 1340 | Belgium | Details | ||
| Centre Hospitalier Universitaire Universite Catholique de Louvain Site Godinne | Yvoir | 5530 | Belgium | Details | ||
| Anhui Provincial Hospital | Hefei | Anhui | 230000 | China | Details | |
| Peking University Third Hospital | Beijing | Beijing | 100000 | China | Details | |
| Beijing Friendship Hospital, Capital Medical University | Beijing | Beijing | 100050 | China | Details | |
| Peking Union Medical College Hospital | Beijing | Beijing | 100730 | China | Details | |
| Second Affiliated Hospital of Army Medical University (Xinqiao Hospital) | Chongqing | Chongqing | 400037 | China | Details | |
| Fujian Medical University Union Hospital | Fuzhou | Fujian | 350001 | China | Details | |
| Quanzhou First Affliated Hospital of Fujian Medical University | Quanzhou | Fujian | 362000 | China | Details | |
| Guangdong Provincial Peoples Hospital | Guangzhou | Guangdong | 510080 | China | Details | |
| Henan Cancer Hospital | Zhengzhou | Henan | 450000 | China | Details | |
| Union Hospital of Tongji Medical College, Huazhong University of Science and Technology | Wuhan | Hubei | 430022 | China | Details | |
| Jiangsu Province Hospital | Nanjing | Jiangsu | 210029 | China | Details | |
| The First Affiliated Hospital of Soochow University Branch Shizi | Suzhou | Jiangsu | 215006 | China | Details | |
| Wuxi Peoples Hospital | Wuxi | Jiangsu | 214023 | China | Details | |
| The First Affiliated Hospital of Nanchang University Branch Donghu | Nanchang | Jiangxi | 330006 | China | Details | |
| The First Hospital of Jilin University | Changchun | Jilin | 130021 | China | Details | |
| West China Hospital, Sichuan University | Chengdu | Sichuan | 610041 | China | Details | |
| Institute of Hematology and Hospital of Blood Disease | Tianjin | Tianjin | 300020 | China | Details | |
| Tianjin Medical University Cancer Institute and Hospital | Tianjin | Tianjin | 300060 | China | Details | |
| The First Affiliated Hospital, Zhejiang University School of Medicine | Hangzhou | Zhejiang | 310003 | China | Details | |
| Fakultni Nemocnice Brno | Brno | 62500 | Czechia | Details | ||
| Fakultni Nemocnice Hradec Kralove | Hradec Kralove | 50005 | Czechia | Details | ||
| Fakultni Nemocnice Olomouc | Olomouc | 77900 | Czechia | Details | ||
| Vseobecna Fakultni Nemocnice V Praze | Praha | 10000 | Czechia | Details | ||
| Centre Hospitalier Victor Dupouy Dargenteuil | Argenteuil cedex | 95107 | France | Details | ||
| Centre de Lutte Contre Le Cancer Institut Bergonie | Bordeaux | 33076 | France | Details | ||
| Chu Caen Normandie | Caen cedex | 14033 | France | Details | ||
| Centre Hospitalier Departemental de Vendee | La Roche sur Yon | 85925 | France | Details | ||
| Centre Hospitalier Le Mans | Le Mans | 72037 | France | Details | ||
| Centre Hospitalier Universitaire Limoges Chu de Limoges | Limoges Cedex | 87042 | France | Details | ||
| Institut Paoli Calmettes | Marseille | 13009 | France | Details | ||
| Centre Hospitalier Universitaire Nantes Hotel Dieu | Nantes Cedex | 44093 | France | Details | ||
| Hopital de La Pitie Salpetriere | Paris | 75013 | France | Details | ||
| Groupe Hospitalier Du Haut Leveque | Pessac Cedex | 33604 | France | Details | ||
| Chu Hopital Lyon Sud | PierreBenite | 69495 | France | Details | ||
| Centre Hospitalier Universitaire de Poitier Hopital de La Miletrie Hopital Jean Bernard | Poitiers | 86000 | France | Details | ||
| Hopital Robert Debre | Reims Cedex | 51056 | France | Details | ||
| Hopital Pontchaillou | Rennes Cedex | 35033 | France | Details | ||
| Centre Henri Becquerel | Rouen Cedex | 76038 | France | Details | ||
| Chu Tours Hopital Bretonneau Service Pneumologie | Tours | 37000 | France | Details | ||
| Chu Nancy Hopital Brabois | VandoeuvrelesNancy | 54511 | France | Details | ||
| Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia | Brescia | 25123 | Italy | Details | ||
| Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori Irst | Meldola | 47014 | Italy | Details | ||
| Fondazione Irccs Ca Granda Ospedale Maggiore Policlinico | Milano | 20122 | Italy | Details | ||
| Ospedale San Raffaele | Milano | 20132 | Italy | Details | ||
| Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda | Milano | 20162 | Italy | Details | ||
| Universita Degli Studi Di Modena Azienda Ospedaliere Policlinco | Modena | 41124 | Italy | Details | ||
| Azienda Unita Sanitaria Locale Di Ravenna | Ravenna | 48121 | Italy | Details | ||
| Universita Degli Studi La Sapienza | Roma | 00161 | Italy | Details | ||
| Fondazione Policlinico Universitario Agostino Gemelli | Roma | 00168 | Italy | Details | ||
| Azienda Ospedaliera S Maria Di Terni | Terni | 05100 | Italy | Details | ||
| Ao Citta Della Salute E Della Scienza Di Torino Presidio O | Torino | 10126 | Italy | Details | ||
| Auckland City Hospital | Auckland | 1023 | New Zealand | Details | ||
| Christchurch Hospital | Christchurch | 8011 | New Zealand | Details | ||
| Palmerston North Hospital | Palmerston North | 4442 | New Zealand | Details | ||
| North Shore Hospital | Takapuna | 0622 | New Zealand | Details | ||
| Tauranga Hospital | Tauranga | 3112 | New Zealand | Details | ||
| Szpital Specjalist W Brzozowie,Podkarpacki Osrodek Onkologiczny | Brzozow | 36-200 | Poland | Details | ||
| Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich | Chorzow | 41-500 | Poland | Details | ||
| Copernicus Podmiot Leczniczy Sp Z Oo Wojewodzkie Centrum Onkologii | Gdansk | 80-219 | Poland | Details | ||
| Szpitale Pomorskie Spolka Z Ograniczona Odpowiedzialnoscia | Gdynia | 81-519 | Poland | Details | ||
| Centrum Onkologii Instytut Im Marii Sklodowskiej Curie, Oddzial W Gliwicach | Gliwice | 44-101 | Poland | Details | ||
| Malopolskie Centrum Medyczne Sc | Krakow | 30-510 | Poland | Details | ||
| Wojewodzki Szpital Specjalistyczny W Legnicy | Legnica | 59-220 | Poland | Details | ||
| Wielospecjalistyczne Centrum Onkologii I Traumatologii Im M Kopernika W Lodzi | Lodz | 93-510 | Poland | Details | ||
| Centrum Onkologii Ziemi Lubelskiej | Lublin | 20-090 | Poland | Details | ||
| Kaluga Regional Hospital | Kaluga | Kaluzhskaya Oblast' | 248000 | Russian Federation | Details | |
| State Healthcare Institution Oncologic Dispensary No Health Department of Krasnodar Region | Sochi | Krasnodarskiy Kray | 354057 | Russian Federation | Details | |
| N N Blokhin Russian Cancer Research Center Konstantin Laktionov | Moscow | Moskva | 115478 | Russian Federation | Details | |
| Russian Academy of Advanced Medical Studies, City Clinical Hospital | Moscow | Moskva | 115478 | Russian Federation | Details | |
| Nizhniy Novgorod Regional Clinical Hospital Nasemashko | Nizhniy Novgorod | Nizhegorodskaya Oblast' | 603126 | Russian Federation | Details | |
| State Budgetary Healthcare Institution Regional Clinical Dispensary | Penza | Penzenskaya Oblast' | 440071 | Russian Federation | Details | |
| State Budgetary Healthcare Institution of Perm Krai Clinical Medical Sanitary Establishment | Perm | Permskiy Kray | 614077 | Russian Federation | Details | |
| Kemerovo Regional Clinical Hospital Na Sv Belyaev | Kemerovo | Pskovskaya Oblast' | 650066 | Russian Federation | Details | |
| Ryazan Regional Clinical Hospital | Ryazan | Ryazanskaya Oblast' | 390039 | Russian Federation | Details | |
| Fgu Russian Scientific Research Institute of Hematology and Transfusiology | Saint Petersburg | Sankt-Peterburg | 191024 | Russian Federation | Details | |
| Sverdlovsk Regional Clinical Hospital | Ekaterinburg | Sverdlovskaya Oblast' | 620102 | Russian Federation | Details | |
| Central City Hospital | Yekaterinburg | Sverdlovskaya Oblast' | 620137 | Russian Federation | Details | |
| Clinical Oncology Dispensary | Kazan | Tambovskaya Oblast' | 420029 | Russian Federation | Details | |
| Tula Area Clinical Hospital | Tula | Tul'skaya Oblast' | 300053 | Russian Federation | Details | |
| State Budgetary Healthcare Institution Volgograd Regional Clinical Oncology Dispensary | Volgograd | Volgogradskaya Oblast' | 400138 | Russian Federation | Details | |
| Hospital Universitari Germans Trias I Pujol | Badalona | 08916 | Spain | Details | ||
| Hospital Del Mar | Barcelona | 08003 | Spain | Details | ||
| Institut Catala Doncologia | Barcelona | 08908 | Spain | Details | ||
| Hospital de La Princesa | Madrid | 28006 | Spain | Details | ||
| Clinica Universidad de Navarra | Madrid | 28027 | Spain | Details | ||
| Hospital Universitario Puerta de Hierro Majadahonda | Majadahonda | 28222 | Spain | Details | ||
| Clinica Universidad de Navarra Pamplona | Pamplona | 31008 | Spain | Details | ||
| Hospital Universitari I Politecnic La Fe | Valencia | 46026 | Spain | Details | ||
| Hospital de Dia Quironsalud Zaragoza | Zaragoza | 50009 | Spain | Details | ||
| Medicinkliniken | Boras | 501 82 | Sweden | Details | ||
| Sahlgrenska Universitetssjukhuset | Goteborg | 416 85 | Sweden | Details | ||
| Skanes Universitetssjukhus I Lund | Lund | 221 85 | Sweden | Details | ||
| Universitetssjukhuset Orebro | Orebro | 701 85 | Sweden | Details | ||
| Karolinska Universitetssjukhuset Solna | Stockholm | 171 76 | Sweden | Details | ||
| Uppsala Akademiska Sjukhus | Uppsala | 75185 | Sweden | Details | ||
| Hualien Tzu Chi Hospital | Hualien | 970 | Taiwan | Details | ||
| Taipei Medical University Shuang Ho Hospital | New Taipei City | 23561 | Taiwan | Details | ||
| National Taiwan University Hospital East Campus | Taipei | 100225 | Taiwan | Details | ||
| Birmingham Heartlands Hospital | Birmingham | B9 5SS | United Kingdom | Details | ||
| The Royal Bournemouth and Christchurch Hospitals Nhs Foundation | Bournemouth | BH7 7DW | United Kingdom | Details | ||
| Cambridge University Hospitals Nhs Foundation Trust | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Kent and Canterbury Hospital | Canterbury | CT1 3NG | United Kingdom | Details | ||
| The Christie Hospital | Greater Manchester | M20 4BX | United Kingdom | Details | ||
| The Leeds Teaching Hospitals Nhs Trust | Leeds | LS9 7TF | United Kingdom | Details | ||
| Barts and the London Nhs Trust | London | EC1M 6BQ | United Kingdom | Details | ||
| Royal Marsden Hospital | London | SW3 6JJ | United Kingdom | Details | ||
| Sarah Cannon Research Institute Uk | London | W1G 6AD | United Kingdom | Details | ||
| Maidstone and Tunbridge Wells Nhs Trust, Kent Oncology Centre, Maidstone Hospital | Maidstone | ME16 9QQ | United Kingdom | Details | ||
| Norfolk and Norwich University Hospitals Nhs Foundation Trust | Norwich | NR4 7UY | United Kingdom | Details | ||
| Nottingham University Hospitals Nhs Trust | Nottingham | NG51PB | United Kingdom | Details | ||
| Derriford Hospital | Plymouth | PL6 8DH | United Kingdom | Details | ||
| Southampton General Hospital | Southampton | SO16 6YD | United Kingdom | Details | ||
| Sunderland Royal Hospital | Sunderland | SR4 7TP | United Kingdom | Details | ||
| The Royal Wolverhampton Nhs Trust | Wolverhampton | WV10 0QP | United Kingdom | Details |