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| NCT ID | NCT03416179 |
| Title | A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia (BRIGHT AML1019) |
| Acronym | BRIGHT AML1019 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Pfizer |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | SWE | ROU | POL | ITA | ISR | HUN | GBR | FRA | ESP | DEU | CZE | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCLA Department of Medicine | Los Angeles | California | 90095 | United States | Details | |
| UCLA Drug Information/Investigational Drugs | Los Angeles | California | 90095 | United States | Details | |
| UCLA Hematology/Oncology Clinic | Los Angeles | California | 90095 | United States | Details | |
| UCLA Ronald Reagan Medical Center | Los Angeles | California | 90095 | United States | Details | |
| UC Irvine Health - Chao Family Comprehensive Cancer Center | Orange | California | 92868-3201 | United States | Details | |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94143 | United States | Details | |
| University of California, San Francisco | San Francisco | California | 94143 | United States | Details | |
| UCLA Hematology/Oncology - Westlake Village | Westlake Village | California | 91361 | United States | Details | |
| Augusta University Medical Center | Augusta | Georgia | 30912 | United States | Details | |
| Georgia Cancer Center at Augusta University | Augusta | Georgia | 30912 | United States | Details | |
| Tufts Medical Center Investigational Drug Pharmacy | Boston | Massachusetts | 02111 | United States | Details | |
| Tufts Medical Center | Boston | Massachusetts | 02111 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
| MidAmerica Division, Inc., c/o Research Medical Center | Kansas City | Missouri | 64132 | United States | Details | |
| Northwell Health/Monter Cancer Center | Lake Success | New York | 11042 | United States | Details | |
| North Shore University Hospital | Manhasset | New York | 11030 | United States | Details | |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | United States | Details | |
| University of Rochester Medical Center | Rochester | New York | 14642 | United States | Details | |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | United States | Details | |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| OHSU Center for Health and Healing | Portland | Oregon | 97239 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States | Details | |
| Centennial Medical Center | Nashville | Tennessee | 37203 | United States | Details | |
| TriStar Bone Marrow Transplant | Nashville | Tennessee | 37203 | United States | Details | |
| Baylor University Medical Center | Dallas | Texas | 75246 | United States | Details | |
| Blood Cancer and Stem Cell Transplant Clinic | San Antonio | Texas | 78229 | United States | Details | |
| Methodist Healthcare System of San Antonio | San Antonio | Texas | 78229 | United States | Details | |
| Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| Swedish Medical Center | Seattle | Washington | 98122 | United States | Details | |
| St Vincent's Hospital Sydney | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| St George Hospital | Kogarah | New South Wales | 2217 | Australia | Details | |
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia | Details | |
| Landeskrankenhaus Salzburg, Universitatsklinik fur Innere Medizin III der PMU | Salzburg | 5020 | Austria | Details | ||
| Uniklinikum Salzburg, Landeskrankenhaus Salzburg | Salzburg | 5020 | Austria | Details | ||
| Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhugel | Wien | 1130 | Austria | Details | ||
| AZ Sint-Jan Brugge-Oostende av | Brugge | B-8000 | Belgium | Details | ||
| Universitaire Ziekenhuizen Brussel (UZ Brussel) | Brussels | B-1090 | Belgium | Details | ||
| Universitaire Ziekenhuizen Brussel | Brussels | B-1090 | Belgium | Details | ||
| Universitaire Ziekenhuizen Leuven | Leuven | B-3000 | Belgium | Details | ||
| Health Sciences Centre | Winnipeg | Manitoba | R3A 1R9 | Canada | Details | |
| CancerCare Manitoba | Winnipeg | Manitoba | R3E 0V9 | Canada | Details | |
| Sunnybrook Research Institute | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| CIUSSS de l'Est-de-l'Ile-de- Montréal - Hôpital Maisonneuve-Rosemont | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Royal University Hospital | Saskatoon | Saskatchewan | S7N 0W8 | Canada | Details | |
| Saskatoon Cancer Centre | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| The First Affiliated Hospital of USTC, Anhui Provincial Hospital | Hefei | Anhui | 230001 | China | Details | |
| Anhui Provincial Hospital | Hefei | Anhui | 230071 | China | Details | |
| Fujian Medical University Union Hospital | Fuzhou | Fujian | 350001 | China | Details | |
| Guangdong Provincial People's Hospital | Guangzhou | Guangdong | 510080 | China | Details | |
| Guangdong Second Provincial General Hospital | Guangzhou | Guangdong | 510317 | China | Details | |
| Hebei Yanda Lu Daopei Hospital | Langfang | Hebei | 065201 | China | Details | |
| Henan Provincial People's Hospital/Hematology Department | Zhengzhou | Henan | 450003 | China | Details | |
| Henan Cancer Hospital | Zhengzhou | Henan | 450008 | China | Details | |
| Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology/Cancer Center | Wuhan | Hubei | 430030 | China | Details | |
| West China Hospital, Sichuan University | Chengdu | Sichuan | 610041 | China | Details | |
| Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences | Tianjin | Tianjin | 300020 | China | Details | |
| The First Affiliated Hospital College of Medicine, Zhejiang University | Hangzhou | Zhejiang | 310003 | China | Details | |
| Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine | Shanghai | 200025 | China | Details | ||
| Interni hematologicka a onkologicka klinika, Fakultni nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
| Nemocnicni lekarna | Brno | 625 00 | Czechia | Details | ||
| Ustavni lekarna | Ostrava - Poruba | 708 52 | Czechia | Details | ||
| Klinika hematoonkologie | Ostrava-Poruba | 708 52 | Czechia | Details | ||
| Interní hematologická klinika, Fakultni nemocnice Královské Vinohrady | Praha 10 | 100 34 | Czechia | Details | ||
| Ústavni lékárna | Praha 10 | 100 34 | Czechia | Details | ||
| CHU Henri Mondor | Créteil | 94010 | France | Details | ||
| CHU de Nantes | Nantes cedex 1 | 44093 | France | Details | ||
| CHU de Nantes Hotel Dieu | Nantes cedex | 44093 | France | Details | ||
| Hopital Saint Louis | Paris | 75010 | France | Details | ||
| Centre Hospitalier Lyon Sud - Service d'Hematologie | Pierre-Benite cedex | 69495 | France | Details | ||
| Institut Gustave Roussy | Villejuif cedex | 94805 | France | Details | ||
| Klinikum der Universitaet Muenchen | Munich | Bavaria | 81377 | Germany | Details | |
| Philipps-Universitaet Marburg | Marburg | Hesse | 35032 | Germany | Details | |
| Universitätsklinikum Köln | Koeln | North Rhine Westphalia | 50937 | Germany | Details | |
| Universitaetsklinikum Muenster | Muenster | North Rhine-westphalia | 48149 | Germany | Details | |
| Universitaetsklinikum Hamburg-Eppendorf | Hamburg | 20246 | Germany | Details | ||
| Medizinische Hochschule Hannover | Hannover | 30625 | Germany | Details | ||
| Debreceni Egyetem Klinikai Kozpont Belgyogyaszati Klinika, Hematologia Tanszek | Debrecen | 4032 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Kozpont Belgyogyaszati Klinika | Debrecen | 4032 | Hungary | Details | ||
| Petz Aladár Megyei Oktató Kórház, II. Belgyógyászat- Hematológiai Osztály | Győr | 9024 | Hungary | Details | ||
| Somogy Megyei Kaposi Mor Oktato Korhaz | Kaposvar | 7400 | Hungary | Details | ||
| Szabolcs-Szatmar Bereg Megyei Korhazak es Egyetemi Oktatokorhaz, Josa Andras Korhaz, Hematologia | Nyiregyhaza | 4400 | Hungary | Details | ||
| Szabolcs-Szatmar Bereg Megyei Korhazak es Egyetemi Oktatokorhaz, Josa Andras Korhaz, | Nyiregyhaza | 4400 | Hungary | Details | ||
| Rambam Health Care Campus | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center | Jerusalem | 9103102 | Israel | Details | ||
| Hadassah Medical Center (Ein Kerem) | Jerusalem | 91120 | Israel | Details | ||
| Hemato-oncology ambulatory Service | Petah Tikva | 4941492 | Israel | Details | ||
| Rabin Medical Center, Beilinson Hospital | Petah Tikva | 4941492 | Israel | Details | ||
| AOU Ospedali Riuniti Umberto I, G.M. Lancisi, G. Salesi, Clinica Di Ematologia | Torrette Di Ancona | Ancona | 60126 | Italy | Details | |
| SOD Farmacia-Dipt dei servizi -AOU Ospedali Riuniti Umberto I, G.M. Lancisi, G. Salesi | Torette Di Ancona | AN | 60126 | Italy | Details | |
| A.O.U. di Ferrara- Arcispedale Sant'Anna, | Cona, Ferrara | FE | 44124 | Italy | Details | |
| AO Ospedali Riuniti Marche Nord - Presidio Ospedaliero San Salvatore di Pesaro - | Pesaro | PU | 61122 | Italy | Details | |
| Azienda Ospedaliera Universitaria Senese. | Siena | SI | 53100 | Italy | Details | |
| Azienda Ospedaliero Universitaria di Bologna Policlinico S.Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Senese | Siena | 53100 | Italy | Details | ||
| Japanese Red Cross Nagoya Daini Hospital | Nagoya | Aichi | 466-8650 | Japan | Details | |
| University of Fukui Hospital | Yoshida-gun | Fukui | 910-1193 | Japan | Details | |
| Gunma University Hospital | Maebashi | Gunma | 371-8511 | Japan | Details | |
| Kobe University Hospital | Kobe-shi | Hyogo | 650-0017 | Japan | Details | |
| Yokohama City University Medical Center | Yokohama | Kanagawa | 232-0024 | Japan | Details | |
| Tohoku University Hospital | Sendai | Miyagi | 980-8574 | Japan | Details | |
| Osaka City University Hospital | Osaka-City | Osaka | 545-8586 | Japan | Details | |
| Kindai University Hospital | Osaka-Sayama | Osaka | 589-8511 | Japan | Details | |
| Shizuoka Cancer Center | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Hospital Organization Disaster Medical Center | Tachikawa | Tokyo | 190-0014 | Japan | Details | |
| Akita University Hospital | Akita | 010-8543 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| National Hospital Organization Kumamoto Medical Center | Kumamoto | 860-0008 | Japan | Details | ||
| Nagasaki University Hospital | Nagasaki | 852-8501 | Japan | Details | ||
| Tokyo Medical University Hospital | Tokyo | 160-0023 | Japan | Details | ||
| Chonbuk National University Hospital | Jeonju-si | Jeollabuk-do | 54907 | Korea, Republic of | Details | |
| Inje University Busan Paik Hospital | Busan | 47392 | Korea, Republic of | Details | ||
| Keimyung University Dongsan Hospital | Daegu | 42601 | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Incheon | 21565 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Clinical Trial Center, Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Instituto Nacional de Cancerología | México | MÉX | 14080 | Mexico | Details | |
| Hospital Universitario "Dr. Jose Eleuterio Gonzalez" | Monterrey | Nuevo LEON | 64460 | Mexico | Details | |
| Klinika Hematologii i Transplantologii Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
| WWCOiT im. M. Kopernika w Lodzi | Lodz | 93-513 | Poland | Details | ||
| Institutul Oncologic 'Prof. Dr. Ion Chiricuta' | Cluj-Napoca | Cluj | 400124 | Romania | Details | |
| Spitalul Clinic Municipal Filantropia Craiova, Sectia Clinica Hematologie | Craiova | Dolj | 200136 | Romania | Details | |
| Sp. Clinic de Urgenta Militar Central Dr. Carol Davila | Bucharest | 010825 | Romania | Details | ||
| Spitalul Clinic Coltea, Clinica de Hematologie | Bucuresti | 030171 | Romania | Details | ||
| State Budgetary Healthcare Institution of Moscow | Moscow | 129301 | Russian Federation | Details | ||
| SBHI NNR NN RCH n. a. N.A. Semashko | Nizhniy Novgorod | 603126 | Russian Federation | Details | ||
| State Budgetary Institution of Ryazan Region 'Regional Clinical Hospital' (SBI RR RCH) | Ryazan | 390039 | Russian Federation | Details | ||
| V.A Almazov NMRC | Saint Petersburg | 197341 | Russian Federation | Details | ||
| Hospital del Mar | Barcelona | 08003 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hospital Universitario Arnau de Vilanova | Lleida | 25198 | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe | Valencia | 46026 | Spain | Details | ||
| Universitetssjukhuset Orebro | Orebro | 701 85 | Sweden | Details | ||
| Karolinska Universitetssjukhuset Huddinge | Stockholm | 141 86 | Sweden | Details | ||
| National Cheng Kung University Hospital | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center | Taipei | 112 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-Linkou Branch | Taoyuan City | 333 | Taiwan | Details | ||
| The Royal Marsden NHS Foundation Trust | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| University Hospitals Birmingham NHS Foundation Trust | Birmingham | WEST Midlands | B15 2TH | United Kingdom | Details | |
| Imperial College Healthcare NHS Trust | London | W12 0HS | United Kingdom | Details |