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| NCT ID | NCT03434379 |
| Title | A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma [IMbrave150] |
| Acronym | IMbrave150 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | POL | ITA | GBR | FRA | ESP | DEU | CZE | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| St. Josephs Hospital and Medical Center | Phoenix | Arizona | 85260 | United States | Details | |
| City of Hope | Duarte | California | 91010 | United States | Details | |
| Uni of California - San Diego; Cancer Center & Dept of Medicine | La Jolla | California | 92093 | United States | Details | |
| Kaiser Permanente Northern California | Novato | California | 94589 | United States | Details | |
| University of California Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| Kaiser Permanente Sacramento Medical Center | Sacramento | California | 95825 | United States | Details | |
| California Pacific Medical Center | San Francisco | California | 94115 | United States | Details | |
| Kaiser Permanente - San Francisco Medical Center | San Francisco | California | 94118 | United States | Details | |
| University of California Los Angeles | Santa Monica | California | 90404 | United States | Details | |
| Kaiser Permanente - Walnut Creek | Walnut Creek | California | 94596 | United States | Details | |
| Banner MD Anderson Cancer Center | Greeley | Colorado | 85234 | United States | Details | |
| Georgetown University | Washington | District of Columbia | 20007 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Washington University; Wash Uni. Sch. Of Med | Saint Louis | Missouri | 63110 | United States | Details | |
| University of New Mexico Comprehensive Cancer Center | Albuquerque | New Mexico | 87102 | United States | Details | |
| Laura and ISAAC Perlmutter Cancer Center at NYU Langone. | New York | New York | 10016 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| M.D Anderson Cancer Center; Uni of Texas At Houston | Houston | Texas | 77030 | United States | Details | |
| Swedish Cancer Inst. | Seattle | Washington | 98104 | United States | Details | |
| Bankstown-Lidcombe Hospital | Bankstown | New South Wales | 2200 | Australia | Details | |
| St George Hospital | Kogarah | New South Wales | 2217 | Australia | Details | |
| The Queen Elizabeth Hospital | Woodville | South Australia | 5011 | Australia | Details | |
| Sunshine Hospital | St Albans | Victoria | 3021 | Australia | Details | |
| Ottawa Hospital Research Institute | Ottawa | Ontario | K1Y 4E9 | Canada | Details | |
| Centre hospitalier de l'Universite de Montreal (CHUM) | Montreal | Quebec | H2X 0A9 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| McGill University Health Centre - Glen Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Peking Union Medical College Hospital | Beijing City | 100032 | China | Details | ||
| Beijing Friendship Hospital | Beijing | 100050 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| the First Hospital of Jilin University | Changchun | 130021 | China | Details | ||
| Jilin Cancer Hospital | Changchun | 132013 | China | Details | ||
| Hunan Cancer Hospital | Changsha CITY | 410013 | China | Details | ||
| The First People's Hospital of Foshan; Local Ethic Committee | Foshan | 510000 | China | Details | ||
| The 900th Hospital of PLA joint service support force | Fuzhou | 110016 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Nanfang Hospital, Southern Medical University | Guangzhou | 510515 | China | Details | ||
| Sir Run Run Shaw Hospital | Hangzhou City | 310018 | China | Details | ||
| Zhejiang Cancer Hospital; Zhejiang Cancer Hospital cancer department | Hangzhou City | 310022 | China | Details | ||
| The First Affiliated Hospital of College of Medicine, Zhejiang University | Hangzhou | 310003 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Anhui Province Cancer Hospital | Hefei City | 230031 | China | Details | ||
| The First Affiliated Hospital of Anhui Medical University | Hefei | 230022 | China | Details | ||
| General Hospital of Jinan Military Command of PLA | Jinan | 250031 | China | Details | ||
| The 81st Hospital of P.L.A. | Nanjing City | 210002 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Zhongshan Hospital Fudan University | Shanghai | 200032 | China | Details | ||
| Tongji Hosp, Tongji Med. Col, Huazhong Univ. of Sci. & Tech | Wuhan | 430030 | China | Details | ||
| Masarykuv onkologicky ustav | Brno | 656 53 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| Hopital Claude Huriez;Gastro Enterologie | Lille | 59037 | France | Details | ||
| Hopital De La Croix Rousse; Hepatologie Gastro Enterologie | Lyon | 69317 | France | Details | ||
| Hopital Timone Adultes; Gastro Enterologie | Marseille | 13385 | France | Details | ||
| Hopital Saint-Eloi; Hepatologie-Gastro-Enterologie | Montpellier | 34295 | France | Details | ||
| Hopital Hotel Dieu Et Hme; Hepatologie Gastro Enterologie | Nantes | 44093 | France | Details | ||
| CHU Nice - Hôpital de l'Archet 2; service Hepato gastro enterologie | Nice Cedex | 06202 | France | Details | ||
| Hopital Charles Nicolle; Gastroenterologie | Rouen | 76031 | France | Details | ||
| Hopital Hautepierre; Gastro Enterologie | Strasbourg | 67098 | France | Details | ||
| Hôpital d'Adultes; Service hépato-gastro-entérologie | Vandoeuvre-les-nancy | 54511 | France | Details | ||
| Institut Gustave Roussy; Gastro-Enterologie | Villejuif | 94805 | France | Details | ||
| Campus Virchow-Klinikum Charité Centrum 13; Medizinische Klinik; Abt.Hepatologie u.Gastroenterologie | Berlin | 13353 | Germany | Details | ||
| Klinik Johann Wolfgang von Goethe Uni; Zentrum der Inneren Medizin; Medizinische Klinik I | Frankfurt | 60590 | Germany | Details | ||
| Universitaetsklinikum Hamburg-Eppendorf; I. Medizinische Klinik - Gastroenterologie | Hamburg | 20246 | Germany | Details | ||
| Med. Hochschule Hannover; Gastroenterologie | Hannover | 30625 | Germany | Details | ||
| Universitätsklinikum Leipzig Medizinische Klinik II Gastroenterolog. u. Hepatolog. | Leipzig | 04103 | Germany | Details | ||
| Uniklinik Mainz; I. Medizinische Klinik | Mainz | 55131 | Germany | Details | ||
| Klinikum der Uni Regensburg; Klinik f.Innere Medizin I Abt. Hämatologie und Internistische Onkologie | Regensburg | 93053 | Germany | Details | ||
| Queen Mary Hospital; Dept. Of Haematology & Oncology | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hosp; Dept. Of Clinical Onc | Shatin | Hong Kong | Details | |||
| Az. Osp. Rummo; Oncologia Medica | Benevento | Campania | 82100 | Italy | Details | |
| IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica | Meldola | Emilia-Romagna | 47014 | Italy | Details | |
| Az. Osp. S. Luigi Gonzaga; Divisione Di Oncologia Medica | Orbassano | Piemonte | 10043 | Italy | Details | |
| A.O.U. Cagliari-P.O. Monserrato;U.O. Oncologia | Cagliari | Sardegna | 09100 | Italy | Details | |
| Azienda Ospedaliero - Universitaria Pisana U.O. Oncologia Medica 2 Universitaria ? Polo Oncologico | Pisa | Toscana | 56126 | Italy | Details | |
| IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Prima | Padova | Veneto | 35128 | Italy | Details | |
| Chiba University Hospital | Chiba | 260-8677 | Japan | Details | ||
| National Cancer Center Hospital East | Chiba | 277-8577 | Japan | Details | ||
| Kurume University Hospital | Fukuoka | 830-0011 | Japan | Details | ||
| Sapporo Kosei Genaral Hospital | Hokkaido | 060-0033 | Japan | Details | ||
| Hokkaido University Hospital | Hokkaido | 060-8648 | Japan | Details | ||
| Kanazawa University Hospital | Ishikawa | 920-8641 | Japan | Details | ||
| Kitasato University Hospital | Kanagawa | 252-0375 | Japan | Details | ||
| Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
| Osaka Metropolitan University Hospital | Osaka | 545-8586 | Japan | Details | ||
| Kindai University Hospital | Osaka | 589-8511 | Japan | Details | ||
| Saga-ken Medical Centre Koseikan | Saga | 840-8571 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| Japanese Red Cross Musashino Hospital | Tokyo | 180-8610 | Japan | Details | ||
| Chonnam National University Hwasun Hospital | Jeollanam-do | 58128 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Ulsan University Hosiptal | Ulsan | 44033 | Korea, Republic of | Details | ||
| Copernicus Podmiot Medyczny Sp. z o.o. Wojewodzkie Centrum Onkologii | Gdansk | 80-219 | Poland | Details | ||
| ID Clinic | Myslowice | 41-400 | Poland | Details | ||
| SP ZOZ MSWiA z WARMINSKO-MAZURSKIM CENTRUM ONKOLOGII; CLINICAL ONCOLOGY, CLINICAL IMMUNOLOGY | Olsztyn | 10-228 | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| Dolno?l?skie Centrum Onkologii; Oddzia? Onkologii Klinicznej i Chemioterapii | Wroc?aw | 53-413 | Poland | Details | ||
| FSBI "National Medical Research Center of Oncology N.N. Blokhin?; Clinical Biotechnologies | Moscow | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| GBUZ Saint Petersburg Clinical Research Center of Specialized Types of Care (Oncology) | Saint Petersburg | Sankt Petersburg | 197758 | Russian Federation | Details | |
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| Tan Tock Seng Hospital; Oncology | Singapore | 308433 | Singapore | Details | ||
| Hospital Universitari Vall d'Hebron; Oncology | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinico San Carlos; Servicio de Oncologia | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario La Paz; Servicio de Oncologia | Madrid | 28046 | Spain | Details | ||
| Centro Integral Oncologico Clara Campal; Servicio de Oncología | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario Miguel Servet; Servicio de Oncologia Medica | Zaragoza | 50009 | Spain | Details | ||
| National Cheng Kung University Hospital; Oncology | Tainan | 00704 | Taiwan | Details | ||
| Chi-Mei Medical Centre; Hematology & Oncology | Tainan | 710 | Taiwan | Details | ||
| Veterans General Hospital; Cancer Center | Taipei | 00112 | Taiwan | Details | ||
| National Taiwan Uni Hospital; Dept of Oncology | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-Linkou; Dept of Oncology | Taoyuan County | 333 | Taiwan | Details | ||
| Beatson West of Scotland Cancer Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| Royal Free Hospital; Dept of Oncology | London | NW3 2QG | United Kingdom | Details | ||
| King'S College Hospital | London | SE5 9RS | United Kingdom | Details | ||
| Christie Hospital Nhs Trust; Medical Oncology | Manchester | M2O 4BX | United Kingdom | Details |