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NCT ID NCT03553836
Title Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications
Therapies
Age Groups: senior | adult | child
Covered Countries USA | POL | ITA | ISR | GBR | FRA | ESP | DEU | CHE | CAN | BRA | BEL | AUS

Facility Status City State Zip Country Details
University of Arizona Cancer Center ( Site 0121) Tucson Arizona 85719 United States Details
UCSD Moores Cancer Center ( Site 0133) La Jolla California 92037 United States Details
The Angeles Clinic and Research Institute ( Site 0029) Los Angeles California 90025 United States Details
UCLA Hematology & Oncology ( Site 0130) Los Angeles California 90095 United States Details
John Wayne Cancer Institute ( Site 0026) Santa Monica California 90404 United States Details
University of Colorado Cancer Center ( Site 0027) Aurora Colorado 80045 United States Details
Yale University ( Site 0035) New Haven Connecticut 06511 United States Details
Mayo Clinic Florida ( Site 0024) Jacksonville Florida 32224 United States Details
Moffitt McKinley Outpatient Center ( Site 0131) Tampa Florida 33612 United States Details
Winship Cancer Institute of Emory University ( Site 0046) Atlanta Georgia 30322-1013 United States Details
Northside Hospital ( Site 0115) Atlanta Georgia 30341 United States Details
Northwestern Medical Group ( Site 0135) Chicago Illinois 60611 United States Details
The University of Chicago Medical Center ( Site 0007) Chicago Illinois 60637 United States Details
Advocate Medical Group-Park Ridge ( Site 0025) Park Ridge Illinois 60068 United States Details
University of Iowa Hospital and Clinics ( Site 0001) Iowa City Iowa 52242 United States Details
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 0047) Baltimore Maryland 21287 United States Details
Massachusetts General Hospital ( Site 0126) Boston Massachusetts 02114 United States Details
Beth Israel Deaconess Medical Center ( Site 0141) Boston Massachusetts 02215 United States Details
Dana Farber Cancer Institute ( Site 0124) Boston Massachusetts 02215 United States Details
Karmanos Cancer Institute ( Site 0111) Detroit Michigan 48201 United States Details
Mayo Clinic [Rochester, MN] ( Site 0016) Rochester Minnesota 55905 United States Details
Siteman Cancer Center ( Site 0143) Saint Louis Missouri 63110 United States Details
Memorial Sloan Kettering ( Site 0006) Harrison New York 10604 United States Details
Laura and Isaac Perlmutter Cancer Center ( Site 0137) New York New York 10016 United States Details
Memorial Sloan Kettering Cancer Center ( Site 0142) New York New York 10022 United States Details
Mount Sinai Medical Center ( Site 0038) New York New York 10029 United States Details
University of Rochester ( Site 0019) Rochester New York 14642 United States Details
The Lindner Center for Research and Education at The Christ Hospital ( Site 0004) Cincinnati Ohio 45219 United States Details
Stephenson Cancer Center ( Site 0042) Oklahoma City Oklahoma 73104 United States Details
Oregon Health & Science University ( Site 0032) Portland Oregon 97239 United States Details
Children's Hospital of Pittsburgh UPMC ( Site 0144) Pittsburgh Pennsylvania 15224 United States Details
UPMC Hillman Cancer Centers ( Site 0043) Pittsburgh Pennsylvania 15232 United States Details
West Cancer Center - East Campus ( Site 0022) Germantown Tennessee 38138 United States Details
University of Tennessee Medical Center Knoxville ( Site 0116) Knoxville Tennessee 37920 United States Details
University of Texas-MD Anderson Cancer Center ( Site 0134) Houston Texas 77030 United States Details
Inova Schar Cancer Institute ( Site 0014) Fairfax Virginia 22031 United States Details
VCU Massey Cancer Center ( Site 0008) Richmond Virginia 23298 United States Details
Seattle Cancer Care Alliance ( Site 0044) Seattle Washington 98109 United States Details
University of Wisconsin Hospital and Clinics ( Site 0030) Madison Wisconsin 53792 United States Details
Melanoma Institute Australia ( Site 0856) North Sydney New South Wales 2065 Australia Details
Westmead Hospital ( Site 0853) Westmead New South Wales 2145 Australia Details
Cairns Base Hospital ( Site 0859) Cairns Queensland 4870 Australia Details
Tasman Oncology Research Pty Ltd ( Site 0858) Southport Queensland 4215 Australia Details
Princess Alexandra Hospital ( Site 0857) Woolloongabba Queensland 4102 Australia Details
Royal Adelaide Hospital ( Site 0861) Adelaide South Australia 5000 Australia Details
Ashford Cancer Centre Research ( Site 0860) Kurralta Park South Australia 5037 Australia Details
The Alfred Hospital ( Site 0852) Melbourne Victoria 3004 Australia Details
Fiona Stanley Hospital ( Site 0851) Murdoch Western Australia 6150 Australia Details
GZA Sint Augustinus ( Site 0259) Wilrijk - Antwerpen Antwerpen 2610 Belgium Details
Cliniques Universitaires Saint-Luc ( Site 0251) Brussels Bruxelles-Capitale, Region De 1200 Belgium Details
Institut Jules Bordet ( Site 0254) Bruxelles Bruxelles-Capitale, Region De 1000 Belgium Details
Jessa Ziekenhuis Campus Virga Jesse ( Site 0256) Hasselt Limburg 3500 Belgium Details
UZ Gent ( Site 0255) Gent Oost-Vlaanderen 9000 Belgium Details
UZ Leuven ( Site 0252) Leuven Vlaams-Brabant 3000 Belgium Details
Hospital Erasto Gaertner ( Site 0159) Curitiba Parana 81520-060 Brazil Details
Hospital de Caridade de Ijui ( Site 0156) Ijui Rio Grande Do Sul 98700 000 Brazil Details
Hospital Sao Vicente de Paulo ( Site 0158) Passo Fundo Rio Grande Do Sul 99010-080 Brazil Details
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 0154) Porto Alegre Rio Grande Do Sul 90610-000 Brazil Details
Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 0155) Barretos Sao Paulo 14784-400 Brazil Details
Hospital de Clinicas de Rio Preto ( Site 0162) Sao Jose Do Rio Preto - SP Sao Paulo 15090-000 Brazil Details
Instituto Nacional do Cancer II ( Site 0160) Rio de Janeiro 20220-410 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0151) Sao Paulo 01246-000 Brazil Details
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0161) Sao Paulo 01321-001 Brazil Details
A.C. Camargo Cancer Center ( Site 0164) Sao Paulo 01508-010 Brazil Details
Cross Cancer Institute ( Site 0057) Edmonton Alberta T6G 1Z2 Canada Details
CancerCare Manitoba ( Site 0053) Winnipeg Manitoba R3E 0V9 Canada Details
Moncton Hospital - Horizon Health Network ( Site 0055) Moncton New Brunswick E1C 6Z8 Canada Details
The Ottawa Hospital ( Site 0058) Ottawa Ontario K1H 8L6 Canada Details
Sunnybrook Research Institute ( Site 0060) Toronto Ontario M4N 3M5 Canada Details
Princess Margaret Cancer Centre ( Site 0059) Toronto Ontario M5G 2M9 Canada Details
Hopital Maisonneuve Rosemont ( Site 0056) Montreal Quebec H1T 2M4 Canada Details
Jewish General Hospital ( Site 0054) Montreal Quebec H3T 1E2 Canada Details
McGill University Health Centre ( Site 0062) Montreal Quebec H4A 3J1 Canada Details
CHU de Quebec - Hotel-Dieu de Quebec ( Site 0061) Quebec G1R 2J6 Canada Details
Instituto Clinico Oncologico del Sur ( Site 0203) Temuco Araucania 4810469 Chile Details
Fundacion Arturo Lopez Perez FALP ( Site 0200) Santiago Region M. De Santiago 7500921 Chile Details
Pontificia Universidad Catolica de Chile ( Site 0201) Santiago Region M. De Santiago 8330032 Chile Details
Sociedad Medica Aren y Bachero Limitada ( Site 0207) Santiago Region M. De Santiago 8420383 Chile Details
Oncocentro ( Site 0204) Vina del Mar Valparaiso 2520598 Chile Details
Centro Oncologico Antofagasta ( Site 0206) Antofagasta 1240000 Chile Details
Hopital La Timone ( Site 0302) Marseille Bouches-du-Rhone 13385 France Details
CHU Dijon Bourgogne ( Site 0320) Dijon Cote-d Or 21000 France Details
CHU de Bordeaux- Hopital Saint Andre ( Site 0304) Bordeaux Gironde 33075 France Details
Institut Claudius Regaud IUCT Oncopole ( Site 0306) Toulouse Haute-Garonne 31059 France Details
Hopital Ambroise Pare Boulogne ( Site 0316) Boulogne-Billancourt Hauts-de-Seine 92100 France Details
CHU Montpellier. ( Site 0312) Montpellier Herault 34295 France Details
Centre Eugene Marquis ( Site 0305) Rennes Ille-et-Vilaine 35042 France Details
CHU Angers ( Site 0321) Angers Maine-et-Loire 49933 France Details
CHU de Reims ( Site 0307) Reims Marne 51100 France Details
CHRU Lille - Hopital Claude Huriez ( Site 0301) Lille Nord 59037 France Details
C.H.U. Lyon Sud ( Site 0303) Pierre Benite Rhone 69495 France Details
CHU Amiens Picardie Hopital Nord ( Site 0317) Amiens Somme 80054 France Details
Institut Gustave Roussy ( Site 0300) Villejuif Val-de-Marne 94805 France Details
Hopital Saint Louis ( Site 0322) Paris 75475 France Details
Universitaetsklinikum in Mannheim ( Site 0351) Mannheim Baden-Wurttemberg 68135 Germany Details
Universitaetsklinikum Tuebingen ( Site 0353) Tuebingen Baden-Wurttemberg 72076 Germany Details
Klinikum der Ludwig-Maximilians-Universitaet Muenchen ( Site 0357) Muenchen Bayern 80337 Germany Details
Klinikum Nuernberg Nord ( Site 0355) Nuernberg Bayern 90419 Germany Details
Klinikum der Universitaet in Wuerzburg ( Site 0356) Wuerzburg Bayern 97080 Germany Details
Elbe Klinikum Buxtehude ( Site 0354) Buxtehude Niedersachsen 21614 Germany Details
Medizinische Hochschule Hannover ( Site 0358) Hannover Niedersachsen 30625 Germany Details
Klinik und Poliklinik fuer Dermatologie Venerologie und Allergologie ( Site 0361) Essen Nordrhein-Westfalen 45147 Germany Details
Universitaetsklinikum Schleswig-Holstein Campus Kiel ( Site 0359) Kiel Schleswig-Holstein 24105 Germany Details
SRH Wald-Klinikum Gera GmbH ( Site 0360) Gera Thuringen 07548 Germany Details
Universitaetsklinikum Hamburg Eppendorf (UKE) ( Site 0352) Hamburg 20246 Germany Details
Soroka Medical Center ( Site 0653) Beer Sheva Southern 8457108 Israel Details
Sourasky Medical Center ( Site 0656) Tel Aviv Tell Abib 6423906 Israel Details
HaEmek Medical Center ( Site 0655) Afula 1834111 Israel Details
Rambam Medical Center ( Site 0654) Haifa 3109601 Israel Details
Hadassah Ein Kerem Medical Center ( Site 0651) Jerusalem 9112001 Israel Details
Chaim Sheba Medical Center. ( Site 0652) Ramat Gan 5262000 Israel Details
Shamir Medical Center-Assaf Harofeh ( Site 0657) Zerifin 70300 Israel Details
Istituto Scientifico Romagnolo per Studio e Cura Tumori IRST ( Site 0403) Meldola Forli-Cesena 47014 Italy Details
IRCCS Giovanni Paolo II. Ospedale Oncologico ( Site 0406) Bari 70124 Italy Details
ASST Papa Giovanni XXIII ( Site 0402) Bergamo 24127 Italy Details
IRCCS A.O.U. San Martino - IST ( Site 0404) Genova 16132 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0408) Milano 20133 Italy Details
Istituto Nazionale Tumori Fondazione Pascale ( Site 0400) Napoli 80131 Italy Details
IRCCS Istituto Oncologico Veneto ( Site 0407) Padova 35128 Italy Details
IDI - Istituto Dermopatico dell'Immacolata ( Site 0405) Roma 00167 Italy Details
Azienda Ospedaliero Universitaria Senese ( Site 0401) Siena 53100 Italy Details
National Cancer Center Hospital ( Site 0910) Tokyo 104-0045 Japan Details
Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 0769) Bydgoszcz Kujawsko-pomorskie 85-796 Poland Details
Pratia MCM Krakow ( Site 0773) Krakow Malopolskie 30-510 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0751) Warszawa Mazowieckie 02-781 Poland Details
Instytut Pomnik Centrum Zdrowia Dziecka ( Site 0759) Warszawa Mazowieckie 04-730 Poland Details
Kliniczny Szpital Wojewodzki Nr 1 ( Site 0758) Rzeszow Podkarpackie 35-055 Poland Details
Uniwersyteckie Centrum Kliniczne ( Site 0770) Gdansk Pomorskie 80-402 Poland Details
Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 0754) Bielsko-Biala Slaskie 43-300 Poland Details
Uniwersyteckie Centrum Kliniczne Slaskiego Uniwersytetu Medycznego ( Site 0757) Katowice Slaskie 40-514 Poland Details
LIFTMED ( Site 0765) Rybnik Slaskie 44-200 Poland Details
Szpital Kliniczny im. Heliodora Swiecickiego Uniwers Medyczn ( Site 0753) Poznan Wielkopolskie 60-780 Poland Details
Cancer Care Langenhoven Drive Oncology Centre ( Site 0812) Port Elizabeth Eastern Cape 6045 South Africa Details
Sandton Oncology Medical Group PTY LTD ( Site 0801) Johannesburg Gauteng 2196 South Africa Details
Charlotte Maxeke Johannesburg Academic Hospital ( Site 0811) Parktown Gauteng 2196 South Africa Details
Wilgers Oncology Centre ( Site 0806) Pretoria Gauteng 0081 South Africa Details
MPOC ( Site 0803) Pretoria Gauteng 0181 South Africa Details
Cancercare ( Site 0810) Cape Town Limpopo 7700 South Africa Details
Cape Town Oncology Trials Pty Ltd ( Site 0807) Kraaifontein Western Cape 7570 South Africa Details
Onkologikoa - Instituto Oncologico de San Sebastian ( Site 0457) San Sebastian Gipuzkoa 20014 Spain Details
Hospital General Universitario de Valencia ( Site 0451) Valencia Valenciana, Comunitat 46014 Spain Details
Hospital General Universitari Vall d Hebron ( Site 0456) Barcelona 08035 Spain Details
Hospital Clinic de Barcelona ( Site 0452) Barcelona 08036 Spain Details
Hospital General Universitario Gregorio Maranon ( Site 0454) Madrid 28009 Spain Details
Hospital Universitario Virgen Macarena ( Site 0455) Sevilla 41009 Spain Details
Universitaetsspital Basel ( Site 0554) Basel Basel-Stadt 4031 Switzerland Details
Universitaetsspital Bern ( Site 0552) Bern Berne 3010 Switzerland Details
Hopitaux Universitaires de Geneve HUG ( Site 0556) Geneva Geneve 1211 Switzerland Details
Kantonsspital Graubuenden ( Site 0555) Chur Grisons 7000 Switzerland Details
Kantonsspital St. Gallen ( Site 0559) St. Gallen Sankt Gallen 9007 Switzerland Details
Oncological Institute of Southern Switzerland ( Site 0557) Bellinzona Ticino 6500 Switzerland Details
Centre Hospitalier Universitaire Vaudois ( Site 0553) Lausanne Vaud 1011 Switzerland Details
Hopital du Valais ( Site 0558) Sion Wallis 1951 Switzerland Details
Universitaetsspital Zuerich ( Site 0551) Zuerich Zurich 8091 Switzerland Details
Addenbrooke's Hospital in Cambridge ( Site 0600) Cambridge Cambridgeshire CB2 0QQ United Kingdom Details
Guy s & St Thomas NHS Foundation Trust ( Site 0601) London London, City Of SE1 9RT United Kingdom Details
Royal Marsden Hospital - Fulham Road London ( Site 0613) London London, City Of SW3 6JJ United Kingdom Details
The Royal Marsden NHS Foundation Trust. ( Site 0612) Sutton Surrey SM2 5PT United Kingdom Details
Christie NHS Foundation Trust ( Site 0604) Manchester M20 4GJ United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field