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NCT ID | NCT03615326 |
Title | Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811) |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | No |
Sponsors | Merck Sharp & Dohme LLC |
Indications | |
Therapies | |
Age Groups: | adult | senior |
Covered Countries | USA | TUR | POL | NZL | ITA | ISR | IRL | GBR | FRA | ESP | DEU | BRA | AUS |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
UCLA Hematology/Oncology - Westwood (Building 200 Suite 120) ( Site 0045) | Los Angeles | California | 90095 | United States | Details | |
Pacific Cancer Care ( Site 0063) | Monterey | California | 93940 | United States | Details | |
UC Irvine Medical Center/Chao Family Comprehensive Cancer Center ( Site 0050) | Orange | California | 92868 | United States | Details | |
University of Miami Sylvester Comprehensive Cancer Center - Plantation ( Site 0026) | Miami | Florida | 33136 | United States | Details | |
Southeastern Regional Medical Center, Inc. ( Site 0058) | Newnan | Georgia | 30265 | United States | Details | |
Midwestern Regional Medical Center, Inc. ( Site 0059) | Zion | Illinois | 60099 | United States | Details | |
Beth Israel Deaconess Medical Center ( Site 0070) | Boston | Massachusetts | 02215 | United States | Details | |
Dana-Farber Cancer Institute [Boston, MA] ( Site 0010) | Boston | Massachusetts | 02215 | United States | Details | |
Minnesota Oncology Hematology, PA ( Site 8001) | Minneapolis | Minnesota | 55404 | United States | Details | |
Washington University School of Medicine ( Site 0040) | Saint Louis | Missouri | 63110 | United States | Details | |
Memorial Sloan Kettering Cancer Center- Monmouth ( Site 0071) | Middletown | New Jersey | 07748 | United States | Details | |
Memorial Sloan-Kettering Cancer Center at West Harrison ( Site 0065) | Harrison | New York | 10604 | United States | Details | |
Memorial Sloan-Kettering Cancer Center ( Site 0017) | New York | New York | 10065 | United States | Details | |
University of Rochester ( Site 0041) | Rochester | New York | 14642 | United States | Details | |
Levine Cancer Institute ( Site 0015) | Charlotte | North Carolina | 28204 | United States | Details | |
Duke Cancer Institute ( Site 0042) | Durham | North Carolina | 27710 | United States | Details | |
CTCA Southwestern ( Site 0060) | Tulsa | Oklahoma | 74133 | United States | Details | |
Cancer Treatment Centers of America-Eastern Regional Medical Center ( Site 0025) | Philadelphia | Pennsylvania | 19124 | United States | Details | |
Allegheny General Hospital ( Site 0053) | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
Sanford Hematology Oncology-Sioux Falls SD ( Site 0004) | Sioux Falls | South Dakota | 57104 | United States | Details | |
University of Texas MD Anderson Cancer Center ( Site 0001) | Houston | Texas | 77030 | United States | Details | |
Oncology & Hematology Assoc. SW Virginia, Inc., DBA Blue Ridge Cancer Care ( Site 8000) | Roanoke | Virginia | 24014 | United States | Details | |
Seattle Cancer Care Alliance ( Site 0038) | Seattle | Washington | 98109 | United States | Details | |
Liverpool Hospital ( Site 2206) | Liverpool | New South Wales | 2170 | Australia | Details | |
Westmead Hospital ( Site 2200) | Westmead | New South Wales | 2145 | Australia | Details | |
Southern Medical Day Care Centre ( Site 2207) | Wollongong | New South Wales | 2500 | Australia | Details | |
Monash Health ( Site 2202) | Clayton | Victoria | 3168 | Australia | Details | |
Hospital Sao Rafael ( Site 0209) | Salvador | Bahia | 41253-190 | Brazil | Details | |
Instituto do Cancer do Ceara ( Site 0208) | Fortaleza | Ceara | 60430-230 | Brazil | Details | |
CIONC - Centro Integrado de Oncologia de Curitiba ( Site 0205) | Curitiba | Parana | 80810-050 | Brazil | Details | |
Hospital de Caridade de Ijui ( Site 0202) | Ijui | Rio Grande Do Sul | 98700 000 | Brazil | Details | |
Hospital Nossa Senhora da Conceicao ( Site 0203) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
CEPON - Centro de Pesquisas Oncologicas ( Site 0200) | Florianopolis | Santa Catarina | 88034-000 | Brazil | Details | |
Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0201) | Rio de Janeiro | 20231-050 | Brazil | Details | ||
IBCC - Instituto Brasileiro de Controle do Cancer ( Site 0204) | Sao Paulo | 03102-002 | Brazil | Details | ||
Centro Investigación del Cáncer James Lind ( Site 0300) | Temuco | Araucania | 4780000 | Chile | Details | |
Clinica Universidad Catolica del Maule ( Site 0305) | Talca | Maule | 3460000 | Chile | Details | |
Fundacion Arturo Lopez Perez FALP ( Site 0302) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
Pontificia Universidad Catolica de Chile ( Site 0301) | Santiago | Region M. De Santiago | 7620002 | Chile | Details | |
Instituto Nacional del Cancer ( Site 0303) | Santiago | Region M. De Santiago | 8380455 | Chile | Details | |
Shanghai General Hospital ( Site 2404) | Shanghai | Anhui | 200080 | China | Details | |
Peking Union Medical College Hospital ( Site 2419) | Beijing | Beijing | 100032 | China | Details | |
Fifth Medical Center of CPLA General Hospital ( Site 2415) | Beijing | Beijing | 100071 | China | Details | |
Beijing Cancer Hospital ( Site 2413) | Beijing | Beijing | 100142 | China | Details | |
Fujian Provincial Cancer Hospital ( Site 2418) | Fuzhou | Fujian | 350014 | China | Details | |
900 Hospital of the Joint ( Site 2420) | Fuzhou | Fujian | 350025 | China | Details | |
The First Affiliated Hospital of Xiamen University ( Site 2431) | Xiamen | Fujian | 361003 | China | Details | |
Guangdong General Hospital ( Site 2433) | Guangzhou | Guangdong | 510080 | China | Details | |
Harbin Medical University Cancer Hospital ( Site 2407) | Harbin | Heilongjiang | 150081 | China | Details | |
Henan Cancer Hospital ( Site 2400) | Zhengzhou | Henan | 450008 | China | Details | |
Xiangya Hospital Central-South University ( Site 2426) | Changsha | Hunan | 410008 | China | Details | |
Jiangsu Cancer Hospital ( Site 2432) | Nanjing | Jiangsu | 210009 | China | Details | |
The First Hospital Of Jilin University ( Site 2402) | Chang chun | Jilin | 130021 | China | Details | |
Fudan University Shanghai Cancer Center ( Site 2424) | Shanghai | Shanghai | 200032 | China | Details | |
Zhongshan Hospital affiliated to Fudan University ( Site 2401) | Shanghai | Shanghai | 200032 | China | Details | |
Cancer Hospital Affiliated to Xinjiang Medical University ( Site 2430) | Urumqi | Xinjiang | 830001 | China | Details | |
The First Affiliated Hospital.Zhejiang University ( Site 2408) | Hangzhou | Zhejiang | 310003 | China | Details | |
Sir Run Run Shaw Hospital ( Site 2412) | Hangzhou | Zhejiang | 310016 | China | Details | |
Zhejiang Cancer Hospital ( Site 2409) | Hangzhou | Zhejiang | 310022 | China | Details | |
CHU de Rouen ( Site 0912) | Rouen | Ain | 76000 | France | Details | |
HUS Hopital Hautepierre ( Site 0910) | Strasbourg | Bas-Rhin | 67098 | France | Details | |
Hopital Jean Minjoz Besancon ( Site 0901) | Besancon | Doubs | 25030 | France | Details | |
C.H.R.U. de Brest - Hopital Morvan ( Site 0913) | Brest | Finistere | 29200 | France | Details | |
Centre Oscar Lambret ( Site 0911) | Lille | Nord | 59000 | France | Details | |
Centre Leon Berard ( Site 0904) | Lyon | Rhone | 69008 | France | Details | |
Institut de Cancerologie de l Ouest Centre Rene Gauducheau ( Site 0902) | Saint-Herblain | Val-de-Marne | 44805 | France | Details | |
Institut Gustave Roussy ( Site 0900) | Villejuif | Val-de-Marne | 94805 | France | Details | |
CHU Hopital Saint Antoine ( Site 0905) | Paris | 75012 | France | Details | ||
SLK-Kliniken Heilbronn ( Site 1015) | Heilbronn | Baden-Wurttemberg | 74078 | Germany | Details | |
Klinikum Ludwigsburg ( Site 1014) | Ludwigsburg | Baden-Wurttemberg | Germany | Details | ||
Innere Medizin I, Universitaetsklinikum Tuebingen ( Site 1020) | Tuebingen | Baden-Wurttemberg | 72076 | Germany | Details | |
Klinikum rechts der Isar der Technischen Universitaet ( Site 1027) | Muenchen | Bayern | 81675 | Germany | Details | |
Medizinische Hochschule Hannover ( Site 1019) | Hannover | Niedersachsen | 30625 | Germany | Details | |
Universitaetsklinikum Carl Gustav Carus der Technischen Univ ( Site 1001) | Dresden | Sachsen | 01307 | Germany | Details | |
Universitaetsklinikum Leipzig AOeR ( Site 1007) | Leipzig | Sachsen | 04103 | Germany | Details | |
Charite-Universitaetsmedizin Berlin Campus Virchow-Klinikum ( Site 1026) | Berlin | 13353 | Germany | Details | ||
Klinikum Bremen Nord ( Site 1017) | Bremen | 28211 | Germany | Details | ||
Facharztzentrum Eppendorf ( Site 1025) | Hamburg | 20249 | Germany | Details | ||
Asklepios Klinik Altona ( Site 1000) | Hamburg | 22763 | Germany | Details | ||
Celan SA ( Site 0504) | Guatemala | 01010 | Guatemala | Details | ||
Oncomedica ( Site 0500) | Guatemala | 01010 | Guatemala | Details | ||
Grupo Angeles SA ( Site 0501) | Guatemala | 01015 | Guatemala | Details | ||
Nucare Center ( Site 0506) | Guatemala | 01015 | Guatemala | Details | ||
Medi-K Cayala ( Site 0505) | Guatemala | 01016 | Guatemala | Details | ||
Centro Regional de Sub Especialidades Medicas SA ( Site 0502) | Quetzaltenango | 09001 | Guatemala | Details | ||
Saint James's Hospital ( Site 1505) | Dublin | D08NHY1 | Ireland | Details | ||
Beaumont Hospital ( Site 1506) | Dublin | D09 V2N0 | Ireland | Details | ||
Tallaght University Hospital ( Site 1513) | Dublin | D24 NR0A | Ireland | Details | ||
Soroka University Medical Center ( Site 1603) | Beer Sheva | 8410101 | Israel | Details | ||
Rambam Health Care Campus ( Site 1606) | Haifa | 3109601 | Israel | Details | ||
Edith Wolfson Medical Center ( Site 1605) | Holon | 5822012 | Israel | Details | ||
Hadassah Ein Kerem Medical Center ( Site 1604) | Jerusalem | 9112001 | Israel | Details | ||
Meir Medical Center ( Site 1609) | Kfar-Saba | 4428132 | Israel | Details | ||
Rabin Medical Center ( Site 1602) | Petah Tikva | 4941492 | Israel | Details | ||
Chaim Sheba Medical Center. ( Site 1607) | Ramat Gan | 5265601 | Israel | Details | ||
Sourasky Medical Center ( Site 1601) | Tel Aviv | 6423906 | Israel | Details | ||
AUOP Ospedale Santa Chiara ( Site 1100) | Pisa | Toscana | 56126 | Italy | Details | |
Humanitas Gavazzeni ( Site 1106) | Bergamo | 24125 | Italy | Details | ||
Universita Magna Graecia di Catanzaro ( Site 1107) | Catanzaro | 88100 | Italy | Details | ||
IEO Istituto Europeo di Oncologia ( Site 1105) | Milano | 20141 | Italy | Details | ||
Azienda Ospedaliero - Universitaria Policlinico di Modena ( Site 1102) | Modena | 41124 | Italy | Details | ||
A.O.U. Universita degli Studi della Campania-Luigi Vanvitelli ( Site 1103) | Napoli | 80131 | Italy | Details | ||
Istituto Oncologico Veneto ( Site 1101) | Padova | 35128 | Italy | Details | ||
Ospedale Civile Spirito Santo ( Site 1104) | Pescara | 65100 | Italy | Details | ||
Aichi Cancer Center Hospital ( Site 2617) | Nagoya | Aichi | 464-8681 | Japan | Details | |
National Cancer Center Hospital East ( Site 2605) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
National Hospital Organization Shikoku Cancer Center ( Site 2615) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
Gunma Prefectural Cancer Center ( Site 2602) | Ohta | Gunma | 373-8550 | Japan | Details | |
Hyogo Cancer Center ( Site 2619) | Akashi | Hyogo | 673-8558 | Japan | Details | |
Kobe City Medical Center General Hospital ( Site 2614) | Kobe | Hyogo | 650-0047 | Japan | Details | |
Ibaraki Prefectural Central Hospital ( Site 2611) | Kasama | Ibaraki | 309-1793 | Japan | Details | |
Kagawa University Hospital ( Site 2604) | Kita-gun | Kagawa | 761-0793 | Japan | Details | |
Kanagawa Cancer Center ( Site 2603) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
Osaki Citizen Hospital ( Site 2626) | Osaki | Miyagi | 989-6183 | Japan | Details | |
Kansai Medical University Hospital ( Site 2618) | Hirakata | Osaka | 573-1191 | Japan | Details | |
Kindai University Hospital ( Site 2616) | Osakasayama | Osaka | 589-8511 | Japan | Details | |
Osaka University Hospital ( Site 2600) | Suita | Osaka | 565-0871 | Japan | Details | |
Saitama Cancer Center ( Site 2620) | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
Shizuoka Cancer Center Hospital and Research Institute ( Site 2607) | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
Tochigi Cancer Center ( Site 2627) | Utsunomiya | Tochigi | 320-0834 | Japan | Details | |
Kyorin University Hospital ( Site 2608) | Mitaka | Tokyo | 181-8611 | Japan | Details | |
Chiba Cancer Center ( Site 2623) | Chiba | 260-8717 | Japan | Details | ||
National Hospital Organization Kyushu Cancer Center ( Site 2609) | Fukuoka | 811-1395 | Japan | Details | ||
Gifu University Hospital ( Site 2621) | Gifu | 501-1194 | Japan | Details | ||
Hiroshima City Hiroshima Citizens Hospital ( Site 2625) | Hiroshima | 730-8518 | Japan | Details | ||
Kumamoto University Hospital ( Site 2601) | Kumamoto | 860-8556 | Japan | Details | ||
Niigata Cancer Center Hospital ( Site 2622) | Niigata | 951-8566 | Japan | Details | ||
National Hospital Organization - Osaka National Hospital - Institute For Clinical Research ( Site 26 | Osaka | 540-0006 | Japan | Details | ||
Osaka International Cancer Institute ( Site 2613) | Osaka | 541-8567 | Japan | Details | ||
Osaka General Medical Center ( Site 2624) | Osaka | 558-8558 | Japan | Details | ||
National Cancer Center Hospital ( Site 2612) | Tokyo | 104-0045 | Japan | Details | ||
Toranomon Hospital ( Site 2628) | Tokyo | 105-8470 | Japan | Details | ||
Tokyo Metropolitan Komagome Hospital ( Site 2606) | Tokyo | 113-8677 | Japan | Details | ||
The Cancer Institute Hospital of JFCR ( Site 2610) | Tokyo | 135-8550 | Japan | Details | ||
Seoul National University Hospital ( Site 2703) | Seoul | 03080 | Korea, Republic of | Details | ||
Severance Hospital Yonsei University Health System ( Site 2700) | Seoul | 03722 | Korea, Republic of | Details | ||
Asan Medical Center ( Site 2702) | Seoul | 05505 | Korea, Republic of | Details | ||
Samsung Medical Center ( Site 2701) | Seoul | 06351 | Korea, Republic of | Details | ||
Auckland City Hospital ( Site 2300) | Auckland | 1023 | New Zealand | Details | ||
Uniwersytecki Szpital Kliniczny im. J. M. Radeckiego we Wroclawiu ( Site 1705) | Wroclaw | Dolnoslaskie | 50-556 | Poland | Details | |
Dolnoslaskie Centrum Onkologii. ( Site 1712) | Wroclaw | Dolnoslaskie | 53-413 | Poland | Details | |
Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 1709) | Lublin | Lubelskie | 20-080 | Poland | Details | |
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
Szpital Morski im. PCK. Szpitale Pomorskie Sp. Z o.o ( Site 1715) | Gdynia | Pomorskie | 81-519 | Poland | Details | |
Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 1708) | Koscierzyna | Pomorskie | 83-400 | Poland | Details | |
Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 1710) | Bielsko-Biala | Slaskie | 43-300 | Poland | Details | |
Przychodnia Lekarska Komed ( Site 1716) | Konin | Wielkopolskie | 62-500 | Poland | Details | |
Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 1807) | Ufa | Baskortostan, Respublika | 450054 | Russian Federation | Details | |
Chelyabinsk Regional Clinical Oncological Dispensary ( Site 1815) | Chelyabinsk | Chelyabinskaya Oblast | 454087 | Russian Federation | Details | |
Podolsky City Clinical Hospital ( Site 1817) | Podolsk | Moskovskaya Oblast | 142110 | Russian Federation | Details | |
Blokhin National Medical Oncology ( Site 1805) | Moscow | Moskva | 115478 | Russian Federation | Details | |
Medical University REAVIZ ( Site 1816) | Samara | Samarskaya Oblast | 443011 | Russian Federation | Details | |
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 1801) | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
St Petersburg City Clinical Oncology Dispensary ( Site 1812) | Saint Petersburg | Sankt-Peterburg | 198255 | Russian Federation | Details | |
Leningrad Regional Oncology Center ( Site 1800) | Saint-Petersburg | Sankt-Peterburg | 188663 | Russian Federation | Details | |
Hospital General Universitario de Elche ( Site 1404) | Elche | Alicante | 03203 | Spain | Details | |
Hospital Universitario Central de Asturias ( Site 1402) | Oviedo | Asturias | 33011 | Spain | Details | |
Hospital Germans Trias i Pujol. ICO de Badalona ( Site 1410) | Badalona | Barcelona | 08916 | Spain | Details | |
Hospital Universitario Marques de Valdecilla ( Site 1405) | Santander | Cantabria | 39008 | Spain | Details | |
Hospital Universitario Quiron Madrid ( Site 1407) | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
Hospital General Universitari Vall d Hebron ( Site 1401) | Barcelona | 08035 | Spain | Details | ||
Hospital Universitario Ramon y Cajal ( Site 1400) | Madrid | 28034 | Spain | Details | ||
Adana Sehir Hastanesi ( Site 2002) | Adana | 01370 | Turkey | Details | ||
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 2017) | Ankara | 06100 | Turkey | Details | ||
Abdurrahman Yurtaslan Onkoloji Egitim ve Arastirma Hastanesi ( Site 2006) | Ankara | 06200 | Turkey | Details | ||
Trakya Universitesi Tip Fakultesi ( Site 2015) | Edirne | 22030 | Turkey | Details | ||
Ataturk Universitesi Tip Fakultesi Hastanesi ( Site 2000) | Erzurum | 25240 | Turkey | Details | ||
Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 2001) | Istanbul | 34098 | Turkey | Details | ||
Dokuz Eylul Universitesi Tip Fakultesi Hastanesi ( Site 2011) | Izmir | 35340 | Turkey | Details | ||
Malatya Inonu Universitesi Tip Fakultesi Hastanesi ( Site 2009) | Malatya | 44280 | Turkey | Details | ||
Sakarya Universitesi Egitim ve Arastirma Hastanesi ( Site 2012) | Sakarya | 54290 | Turkey | Details | ||
City Clinical Hosp.4 of DCC ( Site 2102) | Dnipro | Dnipropetrovska Oblast | 49102 | Ukraine | Details | |
MI Kryviy Rih Center of Dnipropetrovsk Regional Council ( Site 2101) | Kryviy Rih | Dnipropetrovska Oblast | 50048 | Ukraine | Details | |
MI Precarpathian Clinical Oncology Center ( Site 2105) | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
Communal non profit enterprise Regional Clinical Oncology Center ( Site 2112) | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details | |
Medical Center Asklepion LLC ( Site 2115) | Khodosivka | Kyivska Oblast | 08173 | Ukraine | Details | |
Clinic of National Cancer Institute ( Site 2104) | Kyiv | Kyivska Oblast | 03022 | Ukraine | Details | |
Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 2114) | Kyiv | Kyivska Oblast | 03126 | Ukraine | Details | |
Lviv State Oncology Regional Treatment and Diagnostic Center ( Site 2106) | Lviv | Lvivska Oblast | 79031 | Ukraine | Details | |
MI Odessa Regional Oncological Centre ( Site 2108) | Odesa | Odeska Oblast | 65055 | Ukraine | Details | |
Medical Centre LLC Oncolife ( Site 2103) | Zaporizhzhya | Zaporizka Oblast | 69104 | Ukraine | Details | |
Kyiv City Clinical Oncology Centre ( Site 2110) | Kyiv | 03115 | Ukraine | Details | ||
Royal Hospital in Derby ( Site 1514) | Derby | Derbyshire | DE22 3NE | United Kingdom | Details | |
Ninewells Hospital and Medical School ( Site 1504) | Dundee | Dundee City | DD1 9SY | United Kingdom | Details | |
Castle Hill Hospital ( Site 1501) | Cottingham | East Riding Of Yorkshire | HU16 5JQ | United Kingdom | Details | |
University College London Hospital NHS Foundation Trust ( Site 1508) | London | London, City Of | NW1 2PG | United Kingdom | Details | |
St Georges University Hospitals NHS Foundation Trust. ( Site 1500) | London | London, City Of | SW17 0QT | United Kingdom | Details | |
Royal Marsden Hospital ( Site 1510) | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
Royal Marsden NHS Foundation Trust ( Site 1512) | London | SW3 6JJ | United Kingdom | Details | ||
The Christie Hospital NHS Foundation Trust ( Site 1503) | Manchester | M20 4BX | United Kingdom | Details | ||
Mount Vernon Cancer Centre ( Site 1507) | Northwood | HA6 2RN | United Kingdom | Details | ||
Manor Hospital Walsall England ( Site 1515) | Walsall | WS2 9PS | United Kingdom | Details |