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| NCT ID | NCT03631706 |
| Title | M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC) |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | EMD Serono Research & Development Institute, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | NLD | ITA | GRC | FRA | ESP | DEU | CAN | BRA | BEL | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Oncology Specialties, PC; Clearview Cancer Institute | Huntsville | Alabama | 35805 | United States | Details | |
| Cedars Sinai Medical Center - Inflammatory Bowel Disease Center (Clinic | Los Angeles | California | 90048 | United States | Details | |
| UC Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| Kaiser Permanente - Harbor City | San Diego | California | 92120 | United States | Details | |
| Sansum Clinic - Santa Barbara | Santa Barbara | California | 93105 | United States | Details | |
| Rocky Mountain Cancer Centers - Colorado Springs, N. Nevada | Colorado Springs | Colorado | 80907 | United States | Details | |
| Eastern Connecticut Hematology/Oncology Assoc. | Norwich | Connecticut | 06360 | United States | Details | |
| Cancer Specialists, LLC - Department of Clinical Research | Jacksonville | Florida | 32256 | United States | Details | |
| Woodlands Medical Specialists | Pensacola | Florida | 32503 | United States | Details | |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Decatur Memorial Hospital - Clinical Research | Decatur | Illinois | 62526 | United States | Details | |
| Baptist Health Lexington Oncology Associates | Lexington | Kentucky | 40503 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| Henry Ford Medical Center | Detroit | Michigan | 48202 | United States | Details | |
| Health Midwest Ventures Group, Inc d/b/a HCA MidAmerica Division, LLC - Menorah Medical Center - Oncology Account | Kansas City | Missouri | 64132 | United States | Details | |
| Southeast Nebraska Cancer Center | Lincoln | Nebraska | 68510 | United States | Details | |
| The Valley Hospital - Luckow Pavilion | Paramus | New Jersey | 07652 | United States | Details | |
| University of Rochester Medical Center | Rochester | New York | 14642 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| UPMC Cancer Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| SCRI - Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Texas Oncology - Bedford | Bedford | Texas | 76022 | United States | Details | |
| Texas Oncology, P.A. - Sugarland | Sugar Land | Texas | 77479 | United States | Details | |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | United States | Details | |
| Centro de Oncologia e Investigacion Buenos Aires | Berazategui | B1880BBF | Argentina | Details | ||
| Instituto Medico Especializado Alexander Fleming | Ciudad Autonoma Buenos Aires | C1426ANZ | Argentina | Details | ||
| Sanatorio Allende | Cordoba | X5000JHQ | Argentina | Details | ||
| Instituto Medico Rio Cuarto | Rio Cuarto | 5800 | Argentina | Details | ||
| Instituto de Oncología de Rosario | Rosario | S2000KZE | Argentina | Details | ||
| Centro Medico San Roque S.R.L. | San Miguel de Tucuman | 4000 | Argentina | Details | ||
| Universitair Ziekenhuis Brussel - Geriatrie | Bruxelles | 1090 | Belgium | Details | ||
| Jessa Ziekenhuis Hospital | Hasselt | 3500 | Belgium | Details | ||
| UZ Leuven | Pellenberg | 3212 | Belgium | Details | ||
| CHU Mont-Godinne | Yvoir | 5530 | Belgium | Details | ||
| Hospital de Câncer de Barretos - Fundação Pio XII | Barretos | 14784-400 | Brazil | Details | ||
| CRIO - Centro Regional Integrado de Oncologia | Fortaleza | 60336-045 | Brazil | Details | ||
| Hospital São Lucas da PUCRS | Porto Alegre | 90610-000 | Brazil | Details | ||
| INCA - Instituto Nacional de Câncer | Rio de Janeiro | 20230-230 | Brazil | Details | ||
| NOB - Núcleo de Oncologia da Bahia | Salvador | 40170-110 | Brazil | Details | ||
| CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia - Faculdade de Medicina do ABC | Santo Andre | 09060-650 | Brazil | Details | ||
| Saint John Regional Hospital | St. John | New Brunswick | E2L 4L2 | Canada | Details | |
| Tom Baker Cancer Centre | Alberta | T2N 4N2 | Canada | Details | ||
| Stronach Regional Cancer Centre - at Southlake | Ontario | L3Y 2P9 | Canada | Details | ||
| Peking University Cancer Hospital | Beijing | 100142 | China | Details | ||
| Guangdong General Hospital | Guangzhou | 510080 | China | Details | ||
| Shanghai Cancer Hospital, Fudan University | Shanghai | 200032 | China | Details | ||
| Groupe Hospitalier Sud - Hôpital Haut-Lévêque - Maison du Ha | Pessac | Gironde | 33604 | France | Details | |
| Centre Hospitalier Intercommunal de Créteil - Service de Pneumologie | Creteil Cedex | Val De Marne | 94010 | France | Details | |
| Hôpital Nord - AP-HM Marseille# - Service d'Oncologie Multidisciplinaire | Bouches-du-Rhône | 13915 | France | Details | ||
| Centre Léon Bérard | Lyon Cedex 08 | 69373 | France | Details | ||
| CHU Rennes - Hopital Pontchaillou - service de pneumologie | Rennes cedex 09 | 35033 | France | Details | ||
| ICO - Site René Gauducheau | Saint Herblain | 44805 | France | Details | ||
| CHU de Toulouse - Hôpital Larrey - Service de Pneumologie et Oncologie Pneumologique | Toulouse | 31059 | France | Details | ||
| Vivantes Klinikum Am Urban - Haematologie und Onkologie | Berlin | 10967 | Germany | Details | ||
| Asklepios Fachkliniken Muenchen-Gauting - Abteilung Internistische Onkologie | Gauting | 82131 | Germany | Details | ||
| LungenClinic Grosshansdorf | Grosshansdorf | 22927 | Germany | Details | ||
| Medizinische Hochschule Hannover - Pneumologie | Hannover | 30625 | Germany | Details | ||
| Universitaetsklinikum Schleswig- Holstein Campus Luebeck | Luebeck | 23538 | Germany | Details | ||
| Universitaetsklinikum Regensburg - Klinik und Poliklinik fuer Innere Medizin II | Regensburg | Germany | Details | |||
| 251 General Air Force Hospital | Athens | 11525 | Greece | Details | ||
| General Hospital of Athens of Chest Disease "SOTIRIA" | Athens | 11527 | Greece | Details | ||
| University General Hospital of Heraklion "PAGNI" | Heraklion | 71110 | Greece | Details | ||
| General Hospital Papageorgiou-2nd Department of Dermatalogy | Thessaloniki | 56429 | Greece | Details | ||
| Princess Margaret Hospital | Hong Kong | 00000 | Hong Kong | Details | ||
| The University of Hong Kong | Hong Kong | Hong Kong | Details | |||
| The Chinese University of Hong Kong - Emergency Medicine | Shatin | 00000 | Hong Kong | Details | ||
| Azienda Ospedaliera San Giuseppe Moscati - U.O Oncologia Medica | Avellino | 83100 | Italy | Details | ||
| IRCCS Centro di Riferimento Oncologico - Oncologia Medica A | Aviano | 33081 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi - Oncologia Medica | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera Univ. Policlinico Gaspare Rodolico - Unità Operativa di Oncologia | Catania | 95123 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Mater Domini-Campus Universitario - Centro Oncologico | Catanzaro | 88100 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori - Medicina Oncologica I | Milano | 20133 | Italy | Details | ||
| Università degli studi della Campania Luigi Vanvitelli - Dipartimento di Oncologia | Napoli | 80131 | Italy | Details | ||
| NHO Hokkaido Cancer Center - Dept of Respiratory Medicine | Sapporo-shi | Hokkaido | 003-0804 | Japan | Details | |
| National Cancer Center Hospital - Dept of Respiratory Medicine | Chuo-ku | 104-0045 | Japan | Details | ||
| Saitama Medical University International Medical Center - Dept of Respiratory Medicine | Hidaka-shi | Japan | Details | |||
| Saitama Cancer Center | Kitaadachigun | 362-0806 | Japan | Details | ||
| Cancer Institute Hospital of JFCR - Dept of Respiratory Medicine | Koto-ku | 135-8550 | Japan | Details | ||
| Kurume University Hospital | Kurume-shi | 830-0011 | Japan | Details | ||
| Osaka Medical Center for Cancer and Cardiovascular Diseases | Osaka-shi | 541-8567 | Japan | Details | ||
| Kindai University Hospital | Osakasayama-sh | 589-8511 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju-si | Chungcheongbuk-do | 28644 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 13620 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center | Incheon | 21565 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Antoni van Leeuwenhoek Ziekenhuis | Amsterdam | 1066 CX | Netherlands | Details | ||
| VU Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
| Universitair Medisch Centrum Groningen (UMCG) - Parent | Groningen | 9713 GZ | Netherlands | Details | ||
| Maastricht University Medical Center - Dept of Medical Oncology | Maastricht | 6202 AZ | Netherlands | Details | ||
| Erasmus Medisch Centrum | Rotterdam | 3015 CE | Netherlands | Details | ||
| St. Elisabeth Ziekenhuis - Parent | Tilburg | 5022 GC | Netherlands | Details | ||
| Hospital del Mar - Servicio de Oncologia | Barcelona | 08003 | Spain | Details | ||
| Hospital Universitari Quiron Dexeus - Servicio de Oncologia Medica | Barcelona | 08028 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron - Dept of Oncology | Barcelona | 08035 | Spain | Details | ||
| ICO l´Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia | L'Hospitalet de Llobregat | 08908 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon - Servicio de Oncologia Medica | Madrid | 28007 | Spain | Details | ||
| Hospital Universitario 12 de Octubre - Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital Regional Universitario de Malaga | Málaga | 29010 | Spain | Details | ||
| Hospital Universitario Virgen Macarena - Servicio de Oncologia | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio - Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe - Servicio de Oncologia Medica | Valencia | 46026 | Spain | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Tri-Service General Hospital | Taipei | 11490 | Taiwan | Details | ||
| Adana Numune Training and Research Hospital - Cardiology Department | Adana | 01370 | Turkey | Details | ||
| Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital - Oncology Department | Ankara | 06105 | Turkey | Details | ||
| Trakya University Medical Faculty - Medical Oncology | Edirne | 22030 | Turkey | Details | ||
| Kocaeli University Research and Application Hospital | Kocaeli | 41380 | Turkey | Details | ||
| CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU - Ch of Oncology and MR | Dnipro | 49102 | Ukraine | Details | ||
| CI Transcarpathian Cl Onc Center Dep of Surgery#1 SHEI Ivano-Frankivsk NMU - Chair of Oncology | Ivano-Frankivsk | 76018 | Ukraine | Details | ||
| Communal Non-profit Enterprise Regional Center of Oncology - Parent | Kharkiv | 61070 | Ukraine | Details | ||
| Medical and Preventive Treatment Institution Volyn Regional Oncological Dispensary - Dept of Oncochemotherapy | Lutsk | 43018 | Ukraine | Details | ||
| CCCH City Oncological Center SHEI Uzhgorod NU - Ch of R&O of Faculty of PGE&PUT | Uzhgorod | 88000 | Ukraine | Details | ||
| Medical center "Oncolife" | Zaporizhzhia | 69059 | Ukraine | Details |