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| NCT ID | NCT03662126 |
| Title | KRT-232 in Subjects With PMF, Post-PV MF, or Post-ET MF Who Have Failed a JAK Inhibitor |
| Acronym | BOREAS |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Kartos Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | ROU | POL | LTU | ITA | ISR | HUN | HRV | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BGR | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The Kirklin Clinic of UAB Hospital | ACTIVE_NOT_RECRUITING | Birmingham | Alabama | 35294 | United States | Details |
| University of Southern California Norris Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING | Los Angeles | California | 90033 | United States | Details |
| Stanford Cancer Center - Palo Alto | ACTIVE_NOT_RECRUITING | Stanford | California | 94305 | United States | Details |
| Innovative Clinical Research Institute | COMPLETED | Whittier | California | 90603 | United States | Details |
| University Cancer Institute | WITHDRAWN | Boynton Beach | Florida | 33426 | United States | Details |
| Northwestern University Feinberg School of Medicine | COMPLETED | Chicago | Illinois | 60611 | United States | Details |
| University of Illinois at Chicago | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| Dana-Farber Cancer Institute | WITHDRAWN | Boston | Massachusetts | 02215 | United States | Details |
| Washington University School of Medicine | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Brookdale University Hospital and Medical Center | RECRUITING | Brooklyn | New York | 11212 | United States | Details |
| New York Presbyterian/Weill Cornell Medical Center | WITHDRAWN | New York | New York | 10021 | United States | Details |
| Mt. Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| Gabrail Cancer Center | RECRUITING | Canton | Ohio | 44718 | United States | Details |
| The Ohio State University Comprehensive Cancer Center | COMPLETED | Columbus | Ohio | 43210 | United States | Details |
| Oregon Health and Science University | COMPLETED | Portland | Oregon | 97239 | United States | Details |
| Avera Cancer Institute | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Vanderbilt University Medical Center | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| The University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Medical College of Wisconsin - Froedtert Hospital | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Sanatorio de la Mujer | RECRUITING | Rosario | Santa Fe | S2000ORE | Argentina | Details |
| Instituto Medico Alexander Fleming | RECRUITING | Buenos Aires | Argentina | Details | ||
| Centro Medico San Luis | RECRUITING | Caba | 1425 | Argentina | Details | |
| Hospital Privado - Centro Medico de Cordoba - Oncology | RECRUITING | Córdoba | X5016KEH | Argentina | Details | |
| Monash Medical Centre | RECRUITING | Clayton | Victoria | 3168 | Australia | Details |
| Fiona Stanley Hosital | RECRUITING | Murdoch | Western Australia | 6150 | Australia | Details |
| Royal Adelaide Hospital | RECRUITING | Adelaide | Australia | Details | ||
| The Alfred Hospital | RECRUITING | Melbourne | Australia | Details | ||
| South Eastern Private Hospital | RECRUITING | Noble Park | 3174 | Australia | Details | |
| Icon Cancer Center | RECRUITING | South Brisbane | Australia | Details | ||
| Centro de oncologia Leonardo da Vinci | RECRUITING | Fortaleza | Ceara | 60140-025 | Brazil | Details |
| Hospital Erasto Gaertner | RECRUITING | Curitiba | Parana | 81520 | Brazil | Details |
| UNICAMP - Universidade Estadual de Campinas Hemocentro | RECRUITING | Campinas | São Paulo | 13083 | Brazil | Details |
| Hospital das Clínicas UFG | RECRUITING | Goiânia | 74605 | Brazil | Details | |
| Fundacao Doutor Amaral Carvalho | RECRUITING | Jau | 17210-120 | Brazil | Details | |
| Hospital de Clinicas de Porto Alegre - Centro de Pesquisa Clinica | RECRUITING | Porto Alegre | 90035-903 | Brazil | Details | |
| Associação Educadora São Carlos AESC - Hospital Mãe de Deus - Centro de Pesquisa | RECRUITING | Porto Alegre | 90880-480 | Brazil | Details | |
| Instituto de Ensino e Pesquisa São Lucas | RECRUITING | Sao Paulo | 01236-030 | Brazil | Details | |
| Hospital A C Camargo - Fundacao Antonio Prudente | RECRUITING | Sao Paulo | 01509-900 | Brazil | Details | |
| Hospital das Clínicas da Universidade de São Paulo | RECRUITING | Sao Paulo | 05403-000 | Brazil | Details | |
| Instituto D'or de Pesquisa e Ensino | RECRUITING | São Paulo | 04502-001 | Brazil | Details | |
| Instituto COI São Paulo | RECRUITING | São Paulo | 1321001 | Brazil | Details | |
| University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski, Pleven | RECRUITING | Pleven | Bulgaria | Details | ||
| University Multiprofile Hospital for Active Treatment Sveti Georgi, Plovdiv | RECRUITING | Plovdiv | Bulgaria | Details | ||
| Military Medical Academy, Multiprofile for active treatment, Sofia | RECRUITING | Sofia | 1606 | Bulgaria | Details | |
| Acibadem City Clinic Tokuda Hospital, Sofia | RECRUITING | Sofia | Bulgaria | Details | ||
| Specialized Hospital for Active Therapy of Hematological Disorders | RECRUITING | Sofia | Bulgaria | Details | ||
| University Multiprofile Hospital for Active Treatment Alexandrovska, Sofia | WITHDRAWN | Sofia | Bulgaria | Details | ||
| University Multiprofile Hospital for Active Treatment Saint Ivan Rilski, Sofia | RECRUITING | Sofia | Bulgaria | Details | ||
| Princess Margaret Cancer Center | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| General Hospital Sibenik | RECRUITING | Sibenik | 22000 | Croatia | Details | |
| Clinical Hospital Centre Osijek | RECRUITING | Zagreb | 10000 | Croatia | Details | |
| KB Sestre Milosrdnice | RECRUITING | Zagreb | 10000 | Croatia | Details | |
| FN Hradec Kralove | RECRUITING | Králová | 500 05 | Czechia | Details | |
| Vseonecma fakultni nemocrince V Praze | RECRUITING | Nové Město | Czechia | Details | ||
| Fakultní Nemocnice Olomouc | WITHDRAWN | Olomouc | 779 00 | Czechia | Details | |
| Centre Hospitalier Universitaire D'Amiens (Hopital Sud) - Hématologie Clinique | RECRUITING | Amiens | 80054 | France | Details | |
| Center Hospitalier Universitaire d'Angers | RECRUITING | Angers | 49933 Cedex 09 | France | Details | |
| C.H de la Côte Basque - Serviv | RECRUITING | Bayonne | 64100 | France | Details | |
| Centre Hospitalier Regional Universitaire Brest Hopital Morvan | RECRUITING | Brest Cedex | 29609 | France | Details | |
| Centre Hospitalier Universitaire of Caen Normandie - Côte de Nacre | ACTIVE_NOT_RECRUITING | Caen | 14000 | France | Details | |
| Centre Hospitalier Le Mans | RECRUITING | Le Mans | France | Details | ||
| Centre Hospitalier Universitaire de Nîmes | ACTIVE_NOT_RECRUITING | Nîmes | 30029 Cedex 9 | France | Details | |
| Hôpital Saint-Louis | RECRUITING | Paris | 75010 | France | Details | |
| Centre Hospitalier Universitaire de Poitiers | RECRUITING | Poitiers | France | Details | ||
| Institut Universitaire du Cancer de Toulouse Oncopole | RECRUITING | Toulouse | 31059 | France | Details | |
| Hopital Paul Brousse - Aphp Hôpitaux Universitaires Paris Su | RECRUITING | Villejuif | 94800 | France | Details | |
| Klinikum Rechts der Isar der Technischen Universität München Apotheke | RECRUITING | München | Bayern | 81675 | Germany | Details |
| Universitätsklinikum Aachen | ACTIVE_NOT_RECRUITING | Aachen | Nordrhein-Westfalen | 52074 | Germany | Details |
| Universitaetsklinikum Essen | RECRUITING | Essen | Nordrhein-Westfalen | 45147 | Germany | Details |
| Universitätsklinikum Halle | RECRUITING | Halle | Sachsen-Anhalt | 06120 | Germany | Details |
| Gemeinschaftspraxis Haematologie - Onkologie - Hauptstelle | RECRUITING | Dresden | Sachsen | 01307 | Germany | Details |
| Technische Universität Dresden | RECRUITING | Dresden | Sachsen | 01307 | Germany | Details |
| Universitätsklinikum Jena | RECRUITING | Jena | Thuringen | 07747 | Germany | Details |
| Charité Universitätsmedizin Berlin | RECRUITING | Berlin | 13353 | Germany | Details | |
| UKE - Universitätsklinikum Hamburg-Eppendorf | RECRUITING | Hamburg | 20251 | Germany | Details | |
| Universitätsmedizin der Johannes Gutenberg Universität Mainz | ACTIVE_NOT_RECRUITING | Mainz | Germany | Details | ||
| Stauferklinikum Schwäbisch Gmünd | RECRUITING | Mutlangen | 73557 | Germany | Details | |
| Praxis für Hämatologie und Onkologie | RECRUITING | Saarbrücken | 66113 | Germany | Details | |
| University General Hospital of Ioannina | RECRUITING | Ioánnina | Ioannina | 45500 | Greece | Details |
| University Campus of Patras - Hematology | RECRUITING | Patras | 26504 | Greece | Details | |
| AHEPA General Hospital of Thessaloniki | RECRUITING | Thessaloníki | 54636 | Greece | Details | |
| Queen Mary Hospital | RECRUITING | Hong Kong | 150001 | Hong Kong | Details | |
| Prince of Wales Hospital - Medicine | RECRUITING | Shatin | Hong Kong | Details | ||
| Somogy Megyei Kaposi Mór Oktató Kórház | WITHDRAWN | Kaposvár | Somogy | 7400 | Hungary | Details |
| Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház | RECRUITING | Nyíregyháza | Szabolcs-Szatmar-Bereg | 4400 | Hungary | Details |
| Markusovszky Egyetemi Oktatókórház | RECRUITING | Szombathely | Vas | H-9700 | Hungary | Details |
| Semmelweis Egyetem | WITHDRAWN | Budapest | 1083 | Hungary | Details | |
| Dél-pesti Centrumkórház - Országos Hematológiai és Infektológiai Intézet | RECRUITING | Budapest | Hungary | Details | ||
| Debreceni Egyetem Orvos es Egeszsegtudomanyi Centrum | COMPLETED | Debrecen | 4032 | Hungary | Details | |
| Szegedi Tudományegyetem | RECRUITING | Szeged | 6725 | Hungary | Details | |
| Ha'Emek Medical Center | RECRUITING | Afula | 1834111 | Israel | Details | |
| Assuta Ashdod University Hospital | RECRUITING | Ashdod | Israel | Details | ||
| Rambam Medical Centre | RECRUITING | Haifa | 31096 | Israel | Details | |
| Carmel MC | RECRUITING | Haifa | Israel | Details | ||
| Hadassah Medical Organisation | RECRUITING | Jerusalem | 91120 | Israel | Details | |
| Hematology Institute | RECRUITING | Kfar Saba | 44281 | Israel | Details | |
| Western Galilee Hospital - Nahariya | RECRUITING | Nahariya | 22100 | Israel | Details | |
| Rabin Medical Center - Beilinson Hospital | RECRUITING | Petah Tikva | 49100 | Israel | Details | |
| Tel Aviv Sourasky Medical Center - Oncology | RECRUITING | Tel Aviv | 6423906 | Israel | Details | |
| Assuta MC | RECRUITING | Tel Aviv | 64239 | Israel | Details | |
| Assaf Harofeh Medical Center - Hematology | RECRUITING | Zerifin | 7030000 | Israel | Details | |
| A.O. San Gerardo di Monza - L'Ospedale San Gerardo di Monza e l'Università di Milano | RECRUITING | Monza | Lombardia | 20900 | Italy | Details |
| PO Civile SS.Antonio e Biagio | RECRUITING | Alessandria | 15121 | Italy | Details | |
| AOU Ospedali Riuniti Umberto I G.M. Lancisi G. Salesi | RECRUITING | Ancona | 60123 | Italy | Details | |
| A.O.di Bologna Policl.S.Orsola | RECRUITING | Bologna | 41038 | Italy | Details | |
| AO Spedali Civili di Brescia | RECRUITING | Brescia | 25123 | Italy | Details | |
| Azienda Ospedaliero Universitaria Policlinico - Vittorio Emanuele | RECRUITING | Catania | 95123 | Italy | Details | |
| AOU Careggi | RECRUITING | Firenze | 50141 | Italy | Details | |
| Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS | RECRUITING | Meldola | Italy | Details | ||
| Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda | RECRUITING | Milano | 20122 | Italy | Details | |
| ASST Grande Ospedale Metropolitano Niguarda | RECRUITING | Milano | 20162 | Italy | Details | |
| AOU Maggiore della Carità | RECRUITING | Novara | 28100 | Italy | Details | |
| Azienda Ospedaliera Ospedali Riuniti Marche Nord - Pesaro | RECRUITING | Pesaro | 61121 | Italy | Details | |
| Arcispedale S. Maria Nuova, AO di Reggio Emilia | RECRUITING | Reggio Emilia | 42123 | Italy | Details | |
| Policlinico Universitario Agostino Gemelli | RECRUITING | Roma | 00168 | Italy | Details | |
| A.O. Citta della Salute e della Scienza di Torino | RECRUITING | Torino | 10126 | Italy | Details | |
| Inje University Busan Paik Hospital | RECRUITING | Busan | 47392 | Korea, Republic of | Details | |
| Kyungpook National University Hospital | RECRUITING | Daegu | 41944 | Korea, Republic of | Details | |
| Yeungnam University Medical Center | RECRUITING | Daegu | 42415 | Korea, Republic of | Details | |
| Keimyung University Dongsan Medical Center | RECRUITING | Daegu | 42601 | Korea, Republic of | Details | |
| CHA Bundang Medical Center, CHA University | RECRUITING | Seongnam-si | Seongnam-si | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| The Catholic University of Korea, Seoul St. Mary's Hospital | RECRUITING | Seoul | 6591 | Korea, Republic of | Details | |
| Hospital of Lithuanian University of Health Sciences Kaunas | RECRUITING | Kaunas | LT-50161 | Lithuania | Details | |
| Universidad Autonoma de Nuevo Leon (UANL) - Hospital Universitario "Dr. Jose Eleuterio Gonzalez | RECRUITING | Monterrey | Nuevo Leon | 64460 | Mexico | Details |
| Instituto Mexicano del Seguro Social | RECRUITING | Monterrey | 64180 | Mexico | Details | |
| Oaxaca Site Management Organization OSMO | RECRUITING | Oaxaca | 6800 | Mexico | Details | |
| Sociedad de Metabolismo y Corazón S.C. - Oncology | RECRUITING | Veracruz | 91910 | Mexico | Details | |
| Perpetual Succour Hospital - Hemat/Transfusion Med | RECRUITING | Cebu City | 6000 | Philippines | Details | |
| University of the Philippines - Philippine General Hospital | RECRUITING | Manila | 1000 | Philippines | Details | |
| Dolnośląskie Centrum Transplantacji Komórkowych z Krajowym Bankiem Dawców Szpiku | RECRUITING | Wrocław | Dolnoslaskie | 53-439 | Poland | Details |
| Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im. Ks. B. Markiewicza | ACTIVE_NOT_RECRUITING | Brzozow | Podkarpackie | 36-200 | Poland | Details |
| Samodzielny Publiczny Zakład Opieki Zdrowotnej Zespół Szpitali Miejskich | RECRUITING | Chorzów | Slaskie | 41-500 | Poland | Details |
| Szpital Uniwersytecki nr 2 im dr. Jana Biziela | RECRUITING | Bydgoszcz | 86-168 | Poland | Details | |
| Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie | WITHDRAWN | Lublin | 20-081 | Poland | Details | |
| SPZOZ MSWiA z Warminsko - Mazurskim Centrum Onkologii | RECRUITING | Olsztyn | Poland | Details | ||
| Szpital Wojewódzki w Opolu | RECRUITING | Opole | 45-061 | Poland | Details | |
| Clinical Research Center Spółka z Ograniczoną Odpowiedzialnością Medic-R sp. k. | WITHDRAWN | Poznań | 60-848 | Poland | Details | |
| Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Slupsku Sp. z o.o. | RECRUITING | Słupsk | 76-200 | Poland | Details | |
| H. Infante Dom Pedro. Centro Hospitalar do Baixo Vouga | RECRUITING | Aveiro | 3814-501 | Portugal | Details | |
| Hospital de Braga | RECRUITING | Braga | 4710-243 | Portugal | Details | |
| Instituto Português de Oncologia de Coimbra | RECRUITING | Coimbra | 3000-075 | Portugal | Details | |
| H. São Francisco Xavier-Centro Hospitalar Lisboa Ocidental | RECRUITING | Lisboa | 1495-005 | Portugal | Details | |
| Champalimaud Cancer Center | RECRUITING | Lisbon | 1400-038 | Portugal | Details | |
| Cen Med de Diagn si Trat Amb NEOMED | RECRUITING | Brasov | 500283 | Romania | Details | |
| Spitalul Clinic Colentina | RECRUITING | Bucharest | 020125 | Romania | Details | |
| Spitalul Clinic Coltea | RECRUITING | Bucuresti | 030171 | Romania | Details | |
| Medicover | RECRUITING | Bucuresti | 060201 | Romania | Details | |
| Institutul Oncologic "Prof. Dr. Ion Chiricuta" | RECRUITING | Cluj-Napoca | 400015 | Romania | Details | |
| Spitalul Clinic Municipal Filantropia Craiova | RECRUITING | Craiova | 200143 | Romania | Details | |
| Institutul Regional de Oncologie Iasi | RECRUITING | Iaşi | 700483 | Romania | Details | |
| Spitalul Clinic Municipal de Urgenta Timisoara | RECRUITING | Timişoara | 300079 | Romania | Details | |
| Oncomed | RECRUITING | Timişoara | 300329 | Romania | Details | |
| Spitalul Clinic Judetean de Urgenta Tg Mures | RECRUITING | Târgu-Mureş | 540136 | Romania | Details | |
| Clinical oncological dispensary | WITHDRAWN | Omsk | 644013 | Russian Federation | Details | |
| Saint-Petersburg SMU I.P.Pavlov | WITHDRAWN | St Petersburg | 197089 | Russian Federation | Details | |
| Oncologic dispensary of Komi Republic | WITHDRAWN | Syktyvkar | 167904 | Russian Federation | Details | |
| Hospital Universitari Germans Trias i Pujol | RECRUITING | Badalona | Barcelona | 08916 | Spain | Details |
| Hospital Universitario de Gran Canaria Doctor Negrin | RECRUITING | Las Palmas De Gran Canaria | Las Palmas | 35010 | Spain | Details |
| Hospital Universitario Puerta de Hierro - Majadahonda | ACTIVE_NOT_RECRUITING | Majadahonda | Madrid | 28222 | Spain | Details |
| Hospital Universitario Vall d'Hebrón | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital de La Santa Creu i Sant Pau | RECRUITING | Barcelona | 8041 | Spain | Details | |
| Hospital San Pedro de Alcantara | RECRUITING | Cáceres | 1003 | Spain | Details | |
| Hospital Universitario Virgen de la Victoria | RECRUITING | Málaga | 29010 | Spain | Details | |
| Hospital Universitario Son Espases | RECRUITING | Palma de Mallorca | 07120 | Spain | Details | |
| Complejo Hospitalario de Navarra - H. de Navarra, Hematología C/ de Irunlarrea, 3, Pamplona | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Hospital Universitario de Salamanca | RECRUITING | Salamanca | 37007 | Spain | Details | |
| Hospital Universitario Doctor Peset | RECRUITING | Valencia | 46017 | Spain | Details | |
| H. Quirón Zaragoza | RECRUITING | Zaragoza | 50012 | Spain | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei City | Taipei | 100 | Taiwan | Details |
| Chang Gung Medical Foundation - ChiaYi Chang Gung Memorial Hospital - Chiayi Branch | RECRUITING | Chiayi City | Taiwan | Details | ||
| Kaohsiung Medical University - Chung-Ho Memorial Hospital | RECRUITING | Kaohsiung | 807 | Taiwan | Details | |
| China Medical University Hospital | RECRUITING | Taichung | 40447 | Taiwan | Details | |
| Ramathibodi Hospital - Mahidol University - Hematology | RECRUITING | Bangkok | 10400 | Thailand | Details | |
| Siriraj Hospital | RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Thammasat University Hospital | RECRUITING | Khlong Luang | 12120 | Thailand | Details | |
| Srinagarind Hospital (KhonKaen University) | RECRUITING | Khon Kaen | 40002 | Thailand | Details | |
| Songklanagarind Hospital | RECRUITING | Songkhla | 90110 | Thailand | Details | |
| Sakarya Research and Training Hospital | RECRUITING | Adapazarı | 54100 | Turkey | Details | |
| Ankara University Faculty of Medicine | RECRUITING | Ankara | 06500 | Turkey | Details | |
| Gazi University Medical Faculty | RECRUITING | Ankara | 06500 | Turkey | Details | |
| Pamukkale University | RECRUITING | Denizli | 20160 | Turkey | Details | |
| Gaziantep University Faculty of Medicine | RECRUITING | Gaziantep | 27100 | Turkey | Details | |
| Inonu University Turgut Ozal Medical Center | RECRUITING | Malatya | 44280 | Turkey | Details | |
| Mersin University Medical Faculty | RECRUITING | Mersin | 33110 | Turkey | Details | |
| Ondokuz Mayis University Medical Faculty - Hematology | RECRUITING | Samsun | 55280 | Turkey | Details | |
| University Hospitals Birmingham NHS Foundation Trust | ACTIVE_NOT_RECRUITING | Birmingham | United Kingdom | Details | ||
| NHS Greater Glasgow and Clyde | ACTIVE_NOT_RECRUITING | Glasgow | United Kingdom | Details | ||
| Guy's and Saint Thomas' NHS Foundation Trust | ACTIVE_NOT_RECRUITING | London | SE1 9RT | United Kingdom | Details | |
| Oxford University Hospitals NHS Foundation Trust | ACTIVE_NOT_RECRUITING | Oxford | United Kingdom | Details |