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| NCT ID | NCT03668119 |
| Title | A Study of Nivolumab Combined With Ipilimumab and Nivolumab Alone in Patients With Advanced or Metastatic Solid Tumors of High Tumor Mutational Burden (TMB-H) (CheckMate 848) |
| Acronym | CheckMate 848 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA | ROU | POL | NLD | ITA | GBR | FRA | ESP | DNK | DEU | CAN | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| John Wayne Cancer Center | Santa Monica | California | 90404 | United States | Details | |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | United States | Details | |
| Local Institution - 0093 | Minneapolis | Minnesota | 55404 | United States | Details | |
| Broome Oncology | Johnson City | New York | 13790 | United States | Details | |
| Duke Cancer Institute | Durham | North Carolina | 27710 | United States | Details | |
| Local Institution - 0079 | Portland | Oregon | 97239 | United States | Details | |
| Local Institution - 0095 | Austin | Texas | 78731 | United States | Details | |
| Local Institution - 0094 | Dallas | Texas | 75231 | United States | Details | |
| Local Institution - 0090 | Houston | Texas | 77030 | United States | Details | |
| Texas Oncology - Northeast Texas | Tyler | Texas | 75702 | United States | Details | |
| Local Institution - 0016 | Ciudad Autonoma Beunos Aires | Buenos Aires | 1431 | Argentina | Details | |
| Local Institution - 0087 | Ciudad Autónoma de Buenos Aires | Buenos Aires | 1280 | Argentina | Details | |
| Local Institution - 0078 | Caba | 1199 | Argentina | Details | ||
| Local Institution - 0015 | Caba | 1426 | Argentina | Details | ||
| Local Institution - 0119 | Cordoba | 5000 | Argentina | Details | ||
| Local Institution - 0118 | St Leonards | New South Wales | 2065 | Australia | Details | |
| Local Institution - 0062 | Sydney | New South Wales | 2010 | Australia | Details | |
| Local Institution - 0117 | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Local Institution - 0112 | Brussels | 1090 | Belgium | Details | ||
| Local Institution - 0113 | Bruxelles | 1200 | Belgium | Details | ||
| Local Institution - 0114 | Leuven | 3000 | Belgium | Details | ||
| Local Institution - 0010 | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Local Institution - 0060 | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| Local Institution - 0036 | Montreal | Quebec | H2X 3E4 | Canada | Details | |
| Local Institution - 0088 | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Local Institution - 0018 | Santiago | Metropolitana | 8330024 | Chile | Details | |
| Local Institution - 0082 | Santiago | Metropolitana | 8420383 | Chile | Details | |
| Local Institution - 0080 | Copenhagen | 2100 | Denmark | Details | ||
| Local Institution - 0081 | Herlev | 2730 | Denmark | Details | ||
| Local Institution - 0072 | Lyon Cedex 08 | 69373 | France | Details | ||
| Local Institution - 0075 | Marseille Cedex 9 | 13273 | France | Details | ||
| Local Institution - 0073 | Paris Cedex 5 | 75248 | France | Details | ||
| Local Institution - 0074 | Toulouse | 31100 | France | Details | ||
| Local Institution - 0085 | Villejuif | 94805 | France | Details | ||
| Local Institution - 0039 | Berlin | 12200 | Germany | Details | ||
| Local Institution - 0001 | Bonn | 53127 | Germany | Details | ||
| Local Institution - 0002 | Dresden | 01307 | Germany | Details | ||
| Local Institution - 0086 | Essen | 45147 | Germany | Details | ||
| Local Institution - 0043 | Wuerzburg | 97080 | Germany | Details | ||
| Local Institution - 0032 | Genova | 16132 | Italy | Details | ||
| IRCCS Istituto Nazionale Tumori Milano | Milano | 20133 | Italy | Details | ||
| Local Institution - 0029 | Napoli | 80131 | Italy | Details | ||
| Local Institution - 0031 | Siena | 53100 | Italy | Details | ||
| Local Institution - 0116 | Rotterdam | Zuid-Holland | 3015 GD | Netherlands | Details | |
| Local Institution - 0115 | Amsterdam | 1066 CX | Netherlands | Details | ||
| Local Institution - 0076 | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Local Institution - 0077 | Gdansk | 80-214 | Poland | Details | ||
| Fundacion De Investigacion | San Juan | 00927 | Puerto Rico | Details | ||
| Local Institution - 0068 | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| Local Institution - 0069 | Bucuresti | 022328 | Romania | Details | ||
| Local Institution - 0067 | Craiova | 200542 | Romania | Details | ||
| Local Institution - 0070 | Floresti | 407280 | Romania | Details | ||
| Local Institution - 0071 | Timisoara, Timis | 300239 | Romania | Details | ||
| Local Institution - 0065 | Singapore | Central Singapore | 168583 | Singapore | Details | |
| Local Institution - 0066 | Singapore | 117599 | Singapore | Details | ||
| Local Institution - 0084 | Barcelona | 08035 | Spain | Details | ||
| Local Institution - 0083 | Madrid | 28041 | Spain | Details | ||
| Local Institution - 0110 | Pamplona | 31008 | Spain | Details | ||
| Local Institution - 0106 | London | Greater London | W12 OHS | United Kingdom | Details | |
| Local Institution - 0107 | Preston | PR2 9HT | United Kingdom | Details |