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NCT ID NCT03711032
Title Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | TUR | POL | NOR | NLD | ITA | HUN | GRC | GBR | FRA | FIN | ESP | DEU | CHE | CAN | BRA | BEL | AUT | AUS

Facility Status City State Zip Country Details
Alaska Urological Institute dba Alaska Clinical Research Center ( Site 1083) Anchorage Alaska 99503 United States Details
Mayo Clinic in Arizona - Phoenix ( Site 1094) Phoenix Arizona 85054 United States Details
Arizona Urology Specialists (AUS)-Professional Park ( Site 1096) Tucson Arizona 85704 United States Details
UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro Los Angeles California 90095 United States Details
University of California Irvine Medical Center ( Site 1061) Orange California 92868 United States Details
Genesis Research LLC ( Site 1065) Torrance California 90505 United States Details
Colorado Clinical Research ( Site 1100) Lakewood Colorado 80228 United States Details
Urological Research Network ( Site 1106) Hialeah Florida 33016 United States Details
Mayo Clinic in Florida-Urology ( Site 1097) Jacksonville Florida 32224 United States Details
University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 1056) Miami Florida 33136 United States Details
Woodlands Medical Specialists, PA ( Site 8002) Pensacola Florida 32503 United States Details
Emory School of Medicine ( Site 1076) Atlanta Georgia 30322 United States Details
Advanced Urology ( Site 1092) Roswell Georgia 30076 United States Details
Northwestern Memorial Hospital ( Site 1101) Chicago Illinois 60611 United States Details
Wichita Urology Group ( Site 1086) Wichita Kansas 67226 United States Details
Ochsner LSU Health Shreveport - Regional Urology ( Site 1099) Shreveport Louisiana 71106 United States Details
Henry Ford Health System ( Site 1062) Detroit Michigan 48202 United States Details
Michigan Institute of Urology ( Site 1077) Troy Michigan 48084 United States Details
Coastal Urology Associates ( Site 1055) Brick New Jersey 08724 United States Details
Morristown Medical Center ( Site 1090) Morristown New Jersey 07960 United States Details
Rutgers Cancer Institute of New Jersey ( Site 1059) New Brunswick New Jersey 08903 United States Details
St. Peter's Hospital Cancer Care Center ( Site 1087) Albany New York 12208 United States Details
R.J. Zuckerberg Cancer Center ( Site 1080) Lake Success New York 11042 United States Details
Veterans Affairs New York Harbor Healthcare System-PCF COE ( Site 1112) New York New York 10010 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 1074) New York New York 10016 United States Details
Associated Medical Professionals of NY ( Site 1078) Syracuse New York 13210 United States Details
TriState Urologic Services PSC Inc. dba The Urology Group ( Site 1091) Cincinnati Ohio 45212 United States Details
University Hospitals Cleveland Medical Center ( Site 1066) Cleveland Ohio 44106 United States Details
Ohio State University Arthur G James Cancer Hospital & Richard J Solove Research Institute ( Site 10 Columbus Ohio 43210 United States Details
OHSU Knight Cancer Institute ( Site 1075) Portland Oregon 97210 United States Details
Oregon Urology Institute ( Site 1098) Springfield Oregon 97477 United States Details
MidLantic Urology ( Site 1071) Bala-Cynwyd Pennsylvania 19004 United States Details
Lancaster Urology ( Site 1079) Lancaster Pennsylvania 17604 United States Details
University of Pennsylvania ( Site 1088) Philadelphia Pennsylvania 19104 United States Details
Carolina Urologic Research Center ( Site 1085) Myrtle Beach South Carolina 29572 United States Details
Urology Associates [Nashville, TN] ( Site 1072) Nashville Tennessee 37209 United States Details
Urology Clinics of North Texas, PLLC ( Site 1064) Dallas Texas 75231 United States Details
University Of Texas Southwestern Medical Center ( Site 1053) Dallas Texas 75390 United States Details
Texas Oncology-Fort Worth Cancer Center ( Site 8003) Fort Worth Texas 76104 United States Details
Houston Metro Urology ( Site 1111) Houston Texas 77027 United States Details
Texas Oncology-Plano West ( Site 8001) Plano Texas 75093 United States Details
Urology San Antonio Research ( Site 1108) San Antonio Texas 78229 United States Details
University of Vermont Medical Center ( Site 1057) Burlington Vermont 05401 United States Details
Urology of Virginia ( Site 1070) Virginia Beach Virginia 23462 United States Details
GenesisCare North Shore ( Site 0010) St Leonards New South Wales 2065 Australia Details
Northern Cancer Institute. ( Site 0003) St Leonards New South Wales 2065 Australia Details
Sydney Adventist Hospital ( Site 0001) Wahroonga New South Wales 2076 Australia Details
Epworth Hospital ( Site 0009) Richmond Victoria 3121 Australia Details
Ordensklinikum Linz GmbH Elisabethinen ( Site 0052) Linz Oberosterreich 4020 Austria Details
Univ. Klinik f. Urologie Innsbruck ( Site 0051) Innsbruck Tirol 6020 Austria Details
Medizinische Universität Wien ( Site 0054) Vienna Wien 1090 Austria Details
Universitaetsklinik Salzburg ( Site 0053) Salzburg 5020 Austria Details
UZA University Hospital Antwerp ( Site 0105) Edegem Antwerpen 2650 Belgium Details
CHU UCL Namur Site de Godinne ( Site 0103) Yvoir Namur 5530 Belgium Details
O.L.V. Ziekenhuis Aalst ( Site 0106) Aalst Oost-Vlaanderen 9300 Belgium Details
AZ Maria Middelares Gent ( Site 0102) Gent Oost-Vlaanderen 9000 Belgium Details
UZ Gent ( Site 0101) Gent Oost-Vlaanderen 9000 Belgium Details
Hospital São Carlos-Oncocentro Ce ( Site 1558) Fortaleza Ceara 60135-237 Brazil Details
Hospital Erasto Gaertner-CEPEP - Pesquisa Clínica ( Site 1551) Curitiba Parana 81520060 Brazil Details
Fundação Pio XII - Hospital de Câncer de Barretos-Unidade de Pesquisa Clínica ( Site 1553) Barretos Sao Paulo 14784-400 Brazil Details
ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 1560) Sao Paulo 01246-000 Brazil Details
BP - A Beneficencia Portuguesa de São Paulo ( Site 1559) Sao Paulo 01321-001 Brazil Details
Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 1554) Sao Paulo 04014-002 Brazil Details
Exdeo Clinical Research Inc. ( Site 0165) Abbotsford British Columbia V2T 1X8 Canada Details
Silverado Resarch Inc. ( Site 0155) Victoria British Columbia V8T 2C1 Canada Details
Horizon Health Network ( Site 0160) Moncton New Brunswick E1C 6Z8 Canada Details
Princess Margaret Cancer Centre ( Site 0153) Toronto Ontario M5G 2M9 Canada Details
CIUSSS du Saguenay-Lac-St-Jean ( Site 0164) Chicoutimi Quebec G7H 5H6 Canada Details
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0157) Montreal Quebec H1T 2M4 Canada Details
CHUS - Hopital Fleurimont ( Site 0152) Sherbrooke Quebec J1H 5N4 Canada Details
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0 Quebec G1J 1Z4 Canada Details
Cancer Hospital Chinese Academy of Medical Science-Urinary Surgery ( Site 1766) Beijing Beijing 100021 China Details
Peking University First Hospital ( Site 1759) Beijing Beijing 100034 China Details
Beijing Cancer hospital-Urinary Surgery ( Site 1755) Beijing Beijing 100142 China Details
Chongqing University Cancer Hospital ( Site 1784) Chongqing Chongqing 400030 China Details
The First Affiliated hospital of Xiamen University-Urology ( Site 1776) Xiamen Fujian 361003 China Details
SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 1752) Guangzhou Guangdong 510060 China Details
The First Affiliated Hospital of Guangzhou Medical University-Urology ( Site 1777) Guangzhou Guangdong 510120 China Details
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-Urology Surgery ( Site 1751) Guangzhou Guangdong 510289 China Details
ShenZhen People's Hospital ( Site 1778) Shenzhen Guangdong 518020 China Details
Harbin Medical University Cancer Hospital-urology ( Site 1772) Harbin Heilongjiang 150081 China Details
Henan Cancer Hospital-Urology ( Site 1770) Zhengzhou Henan 450008 China Details
Tongji Hospital Tongji Medical,Science & Technology ( Site 1768) Wuhan Hubei 430000 China Details
Wuhan Union Hospital ( Site 1771) Wuhan Hubei 430010 China Details
Hunan Cancer Hospital ( Site 1763) Changsha Hunan 410013 China Details
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S NanJing Jiangsu 210008 China Details
The Second Affiliated Hospital of Soochow University-Urology ( Site 1773) Suzhou Jiangsu 215004 China Details
The First Affiliated Hospital of Xi'an Jiaotong University ( Site 1764) Xi'an Shaanxi 710061 China Details
West China Hospital Sichuan University ( Site 1767) Cheng Du Sichuan 610041 China Details
The Second Hospital of Tianjin Medical University ( Site 1769) Tianjin Tianjin 300211 China Details
Zhejiang Provincial People's Hospital-Urology ( Site 1762) Hangzhou Zhejiang 310014 China Details
The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 1774) Wenzhou Zhejiang 325000 China Details
Instituto de Cancerología-Oncology ( Site 1609) Medellín Antioquia 050024 Colombia Details
Fundación Hospital San Vicente de Paúl - Rionegro - Centros Especializados o de Centros Especializad Rionegro Antioquia 054047 Colombia Details
Oncomedica S.A.-Oncomedica S.A ( Site 1604) Montería Cordoba 230002 Colombia Details
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 1605) Bogota Distrito Capital De Bogota 111321 Colombia Details
Administradora Country S.A. - Clinica del Country ( Site 1607) Bogotá Distrito Capital De Bogota 110221 Colombia Details
Oncologos del Occidente ( Site 1608) Pereira Risaralda 661001 Colombia Details
Hemato Oncologos SA-Oncology ( Site 1601) Cali Valle Del Cauca 76001 Colombia Details
Clínica Imbanaco S.A.S ( Site 1611) Cali Valle Del Cauca 760042 Colombia Details
CIMCA ( Site 1550) San José San Jose 10103 Costa Rica Details
Policlinico San Bosco ( Site 0600) San Jose 10103 Costa Rica Details
Tampere University Hospital [Tampere Finland] ( Site 0201) Tampere Pirkanmaa 33520 Finland Details
Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand-Urology ( Site 1355) Dijon Bourgogne 21000 France Details
Hôpital Foch-Urology department ( Site 1351) Suresnes Hauts-de-Seine 92150 France Details
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou ( Site 1353) Rennes Ille-et-Vilaine 35000 France Details
Hopital Claude Huriez - CHU de Lille ( Site 1360) Lille Nord 59037 France Details
HENRI MONDOR HOSPITAL ( Site 1357) Créteil Seine-et-Marne 94000 France Details
Klinikum Rechts der Isar. Technischen Universitaet Muenchen ( Site 0266) Munich Bayern 81675 Germany Details
Klinikum Weiden ( Site 0259) Weiden In Der Oberpfalz Bayern 92637 Germany Details
Universitaetsklinikum Wuerzburg ( Site 0265) Wuerzburg Bayern 97080 Germany Details
Krankenhaus der Barmherzigen Brüder Trier-Abteilung für Urologie und Kinderurologie ( Site 0262) Trier Rheinland-Pfalz 54292 Germany Details
Universitaetsklinikum Jena ( Site 0252) Jena Thuringen 07747 Germany Details
Olympion General Clinic ( Site 0306) Patras Achaia 264 43 Greece Details
General University Hospital of Patras ( Site 0302) Patra Achaia 265 04 Greece Details
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0304) Chaidari Attiki 124 62 Greece Details
Antikarkiniko Nosokomeio Thessalonikis THEAGENIO ( Site 0303) Thessaloniki Kentriki Makedonia 54007 Greece Details
University Hospital of Larissa ( Site 0301) Larissa Thessalia 411 10 Greece Details
Onco Go, S.A ( Site 1454) Guatemala City 01010 Guatemala Details
INTEGRA Cancer Institute ( Site 1451) Guatemala 01010 Guatemala Details
Grupo Medico Angeles ( Site 1453) Guatemala 01015 Guatemala Details
Pécsi Tudományegyetem Klinikai Központ-Urológiai Klinika ( Site 1304) Pécs Baranya 7621 Hungary Details
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Urológiai Klinika ( Site 1303) Szeged Csongrad 6725 Hungary Details
Semmelweis University-Urológiai Klinika ( Site 1301) Budapest 1082 Hungary Details
Debreceni Egyetem Klinikai Kozpont ( Site 1302) Debrecen 4032 Hungary Details
Ospedale Clinicizzato Santissima Annunziata ( Site 0361) Chieti Abruzzo 66100 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0353) Milan Milano 20133 Italy Details
Ospedale Mauriziano-SCDU ONCOLOGIA MEDICA ( Site 0366) Torino Piemonte 10128 Italy Details
Azienda Ospedaliero Universitaria Careggi ( Site 0360) Firenze Toscana 50134 Italy Details
Osp Generale Reg di Bolzano ( Site 0355) Bolzano Trentino-Sudtirol 39100 Italy Details
Azienda USL 8 di Arezzo-Medical Oncology ( Site 0363) Arezzo 52100 Italy Details
Istituto Tumori Giovanni Paolo II ( Site 0357) Bari 70124 Italy Details
Ospedale San Martino ( Site 0351) Genova 16132 Italy Details
IRCCS Ospedale San Raffaele ( Site 0362) Milano 20132 Italy Details
Ospedale Buccheri La Ferla Fatebenefratelli ( Site 0352) Palermo 90123 Italy Details
Policlinico Universitario A. Gemelli ( Site 0358) Roma 00168 Italy Details
A.O.U. di Verona - Ospedale Civile Maggiore Borgo Trento ( Site 0356) Verona 37126 Italy Details
Hirosaki University Hospital ( Site 0407) Hirosaki Aomori 036-8563 Japan Details
Ehime University Hospital ( Site 0414) Toon Ehime 791-0295 Japan Details
University of Tsukuba Hospital ( Site 0412) Tsukuba Ibaraki 305-8576 Japan Details
St. Marianna University Hospital ( Site 0415) Kawasaki Kanagawa 216-8511 Japan Details
Kitasato University Hospital ( Site 0403) Sagamihara Kanagawa 252-0375 Japan Details
Yokosuka Kyosai Hospital ( Site 0406) Yokosuka Kanagawa 238-8558 Japan Details
Nara Medical University Hospital ( Site 0411) Kashihara Nara 634-8522 Japan Details
Hamamatsu University Hospital ( Site 0416) Hamamatsu Shizuoka 431-3192 Japan Details
Chiba Cancer Center ( Site 0401) Chiba 260-8717 Japan Details
Harasanshin Hospital ( Site 0410) Fukuoka 812-0033 Japan Details
Osaka International Cancer Institute ( Site 0413) Osaka 541-8567 Japan Details
Osaka Metropolitan University Hospital ( Site 0404) Osaka 545-8586 Japan Details
Institute of Science Tokyo Hospital ( Site 0409) Tokyo 113-8519 Japan Details
Keio University Hospital ( Site 0405) Tokyo 160-8582 Japan Details
Asan Medical Center ( Site 0804) Songpagu Seoul 05505 Korea, Republic of Details
Korea University Anam Hospital ( Site 0801) Seoul 02841 Korea, Republic of Details
Seoul National University Hospital ( Site 0802) Seoul 03080 Korea, Republic of Details
Samsung Medical Center ( Site 0803) Seoul 06351 Korea, Republic of Details
University Malaya Medical Centre ( Site 1180) Kuala Lumpur 59100 Malaysia Details
Maastricht University Medical Centre ( Site 0453) Maastricht Limburg 6229 HX Netherlands Details
Erasmus MC ( Site 0451) Rotterdam Zuid-Holland 3015 GD Netherlands Details
Universitair Medisch Centrum Utrecht-Medical Oncology ( Site 0455) Utrecht 3584 CX Netherlands Details
Akershus University Hospital ( Site 0553) Lorenskog Akershus 1478 Norway Details
Stavanger universitetssykehus ( Site 0555) Stavanger Rogaland 4011 Norway Details
Hospital Nacional Guillermo Almenara Irigoyen ( Site 0601) La Victoria Lima 15033 Peru Details
Oncosalud ( Site 0603) Lima Muni Metro De Lima 15036 Peru Details
Hospital Militar Central [Lima, Peru] ( Site 0604) Lima 15076 Peru Details
Uniwesytecki Szpital Kliniczny we Wroclawiu ( Site 0669) Wroclaw Dolnoslaskie 50-556 Poland Details
MICS Centrum Medyczne Torun ( Site 0679) Torun Kujawsko-pomorskie 87-100 Poland Details
Pratia MCM Krakow ( Site 0668) Krakow Malopolskie 30-510 Poland Details
Szpital Wojewódzki im. Świętego Lukasza SP ZOZ w Tarnowie ( Site 0681) Tarnow Malopolskie 33-100 Poland Details
Urologica Praktyka Lekarska Adam Marcheluk ( Site 0654) Siedlce Mazowieckie 08-110 Poland Details
Medical Concierge Centrum Medyczne ( Site 0676) Warsaw Mazowieckie 02-798 Poland Details
Luxmed Onkologia sp. z o. o. ( Site 0653) Warszawa Mazowieckie 01-748 Poland Details
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 0678) Przemysl Podkarpackie 37-700 Poland Details
Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0671) Koscierzyna Pomorskie 83-400 Poland Details
Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Slupsku ( Site 0655) Slupsk Pomorskie 76-200 Poland Details
LIFTMED ( Site 0652) Rybnik Slaskie 44-200 Poland Details
Clinical Research Center Sp. z o.o. ( Site 0674) Poznan Wielkopolskie 61-731 Poland Details
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 0702) Lisbon Lisboa 1649-035 Portugal Details
Unidade Local de Saude de Braga - Hospital de Braga ( Site 0705) Braga 4710-243 Portugal Details
Inst. Portugues de Oncologia de Coimbra Francisco Gentil EPE ( Site 0704) Coimbra 3000-075 Portugal Details
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0708) Lisboa 1099-023 Portugal Details
Hospital CUF Descobertas ( Site 0706) Lisboa 1998-018 Portugal Details
Inst. Portugues de Oncologia de Porto Francisco Gentil EPE ( Site 0701) Porto 4200-072 Portugal Details
Advance Urology and Laparoscopic Center ( Site 0757) Ponce 00716 Puerto Rico Details
Ad-Vance Medical Research ( Site 0756) Ponce 00717 Puerto Rico Details
Hospital Universitario Lucus Augusti ( Site 0852) Lugo La Coruna 27003 Spain Details
Hospital Universitario Quiron Madrid ( Site 0862) Pozuelo de Alarcon Madrid, Comunidad De 28223 Spain Details
Clinica Universitaria de Navarra ( Site 0863) Pamplona Navarra 31008 Spain Details
Fundacio Puigvert ( Site 0864) Barcelona 08025 Spain Details
Hospital Universitario Gregorio Maranon ( Site 0854) Madrid 28007 Spain Details
Clinica Universitaria Navarra - Madrid ( Site 0860) Madrid 28027 Spain Details
MD Anderson Cancer Center Madrid ( Site 0859) Madrid 28033 Spain Details
Hospital Universitario Ramon y Cajal ( Site 0857) Madrid 28034 Spain Details
Hospital Universitario La Paz ( Site 0866) Madrid 28046 Spain Details
Hospital La Fe de Valencia ( Site 0855) Valencia 46026 Spain Details
Universitaetsspital Basel ( Site 1201) Basel Basel-Stadt 4031 Switzerland Details
Hopitaux Universitaires de Geneve HUG ( Site 1204) Geneve 1205 Switzerland Details
Universitaetsspital Zurich ( Site 1203) Zurich 8091 Switzerland Details
Ankara Universitesi Tip Fakultesi Hastanesi ( Site 0966) Ankara 06590 Turkey Details
Eskisehir Osmangazi Universitesi Hastanesi ( Site 0953) Eskisehir 26480 Turkey Details
Memorial Sisli Hastanesi-Medical Oncology ( Site 0965) Istanbul 34385 Turkey Details
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0963) Istanbul 34722 Turkey Details
Dokuz Eylul Universitesi ( Site 0959) Izmir 35340 Turkey Details
Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 0961) Konya 42000 Turkey Details
Raigmore Hospital ( Site 1006) Inverness Highland IV2 3UJ United Kingdom Details
St Bartholomew s Hospital ( Site 1008) London London, City Of EC1A 7BE United Kingdom Details
St Georges University Hospitals NHS Foundation Trust. ( Site 1005) London London, City Of SW17 0QT United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field