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| NCT ID | NCT03729245 |
| Title | A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC) |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Nektar Therapeutics |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NZL | BRA | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alaska Urological | Anchorage | Alaska | 99503 | United States | Details | |
| Western Regional Medical Center - CTCA - PPDS | Goodyear | Arizona | 85338 | United States | Details | |
| CARTI Cancer Center | Little Rock | Arkansas | 72205 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010 | United States | Details | |
| University of California Irvine | Orange | California | 92868 | United States | Details | |
| Innovative Clinical Research Institute | Whittier | California | 90603 | United States | Details | |
| University of Miami | Miami | Florida | 33136 | United States | Details | |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | United States | Details | |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | 21201 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89106 | United States | Details | |
| North Shore Hematology Oncology Association PC | Port Jefferson Station | New York | 11776 | United States | Details | |
| Kettering Medical Center | Kettering | Ohio | 45429 | United States | Details | |
| Providence Cancer Institute, Franz Clinic | Portland | Oregon | 97213 | United States | Details | |
| Lehigh Valley Physician Group (LVPG) - Hematology Oncology | Allentown | Pennsylvania | 18103 | United States | Details | |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Eastern Regional Medical Center - CTCA | Philadelphia | Pennsylvania | 19124 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Huntsman Cancer Hospital - PPDS | Salt Lake City | Utah | 84112 | United States | Details | |
| Centro de Investigación Clínica - Clínica Viedma | Viedma | Rio Negro | R8500ACE | Argentina | Details | |
| Centro de Investigación Pergamino S.A | Buenos Aires | 2700 | Argentina | Details | ||
| Centro Médico Austral | Buenos Aires | C1019ABS | Argentina | Details | ||
| Instituto Médico Especializado Alexander Fleming | Buenos Aires | C1426ANZ | Argentina | Details | ||
| Centro Médico Privado CEMAIC | Córdoba | X5000HHW | Argentina | Details | ||
| Sanatorio Allende S.A. | Córdoba | X5000JHQ | Argentina | Details | ||
| Sanatorio Privado Duarte Quirós, de Clínica Colombo S.A. | Córdoba | X5002AOQ | Argentina | Details | ||
| Centro Oncologico Riojano Integral (cori) | La Rioja | F5300COE | Argentina | Details | ||
| Hospital Provincial Del Centenario | Rosario | S2002KDS | Argentina | Details | ||
| CAIPO Centro para la atención integral del paciente oncológico | San Miguel De Tucumán | 4000 | Argentina | Details | ||
| Sanatorio Parque de Rosario | Santa Fe | S2000DSV | Argentina | Details | ||
| Orange Cancer Centre | Orange | New South Wales | 2800 | Australia | Details | |
| Royal North Shore Hospital | Saint Leonards | New South Wales | 2065 | Australia | Details | |
| Macquarie University | Sydney | New South Wales | 2109 | Australia | Details | |
| Adelaide Cancer Centre | Kurralta Park | South Australia | 5037 | Australia | Details | |
| Barwon Health | Parkville | Victoria | 3050 | Australia | Details | |
| Centro de Oncologia Da Bahia | Salvador | Bahia | 41820-021 | Brazil | Details | |
| Ensino E Terapia de Inovação Clínica Assistência Multidiciplinar Em Oncologia Ética | Salvador | Bahia | 41950-610 | Brazil | Details | |
| Cenantron - Centro Avancado de Tratamento Oncologico Ltda | Belo Horizonte | Minas Gerais | 30190-130 | Brazil | Details | |
| Oncocentro, Belo Horizonte | Belo Horizonte | Minas Gerais | 30360-680 | Brazil | Details | |
| Liga Paranaense de Combate Ao Cancer - Hospital Erasto Gaertner | Curitiba | Parana | 80060-900 | Brazil | Details | |
| Liga Norte Riograndense Contra O Cancer | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details | |
| Associação Hospital de Caridade Ijuí | Ijuí | Rio Grande Do Sul | 98700-000 | Brazil | Details | |
| Hospital Bruno Born | Lajeado | Rio Grande Do Sul | 95900-000 | Brazil | Details | |
| Universidade Federal do Rio Grande do Sul - UFRGS | Porto Alegre | Rio Grande Do Sul | 90035-903 | Brazil | Details | |
| Irmandade Da Santa Casa de Misericordia de Porto Alegre | Porto Alegre | Rio Grande Do Sul | 90050-170 | Brazil | Details | |
| Hospital Mae de Deus | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details | |
| Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul (PUCRS) | Porto Alegre | Rio Grande Do Sul | 90610-000 | Brazil | Details | |
| Clínica de Oncologia de Porto Alegre SS Ltda | Rio Grande | Rio Grande Do Sul | 90430-090 | Brazil | Details | |
| Instituto Joinvilense de Hematologia E Oncologia | Joinville | Santa Catarina | 89201-260 | Brazil | Details | |
| Fundação Pio XII Hospital de Câncer de Barretos | Barretos | Sao Paulo | 14784-400 | Brazil | Details | |
| Hospital das Clinicas - UNICAMP | Campinas | Sao Paulo | 13083-887 | Brazil | Details | |
| Fundação do ABC - Faculdade de Medicina do ABC | Santo André | Sao Paulo | 09060-650 | Brazil | Details | |
| Hospital Amaral Carvalho | Jaú | São Paulo | 17210-120 | Brazil | Details | |
| Instituto de Pesquisas Clínicas Para Estudos Multicêntricos | Caxias Do Sul | 95070-560 | Brazil | Details | ||
| Instituto Do Câncer Do Ceará ICC | Fortaleza | 60430-230 | Brazil | Details | ||
| Animi | Lages | 88501-001 | Brazil | Details | ||
| Instituto Nacional de Câncer | Rio De Janeiro | 20231-050 | Brazil | Details | ||
| Instituto COI de Pesquisa, Educação e Gestão | Rio De Janeiro | 22793-080 | Brazil | Details | ||
| Hospital de Base Da Faculdade de Medicina de São José Do Rio Preto | São José Do Rio Preto | 15090-000 | Brazil | Details | ||
| Hospital Alemão Oswaldo Cruz | São Paulo | 01323-903 | Brazil | Details | ||
| Fundação Antônio Prudente - AC Camargo Câncer Center | São Paulo | 01508-010 | Brazil | Details | ||
| Hospital Santa Marcelina | São Paulo | 08270-120 | Brazil | Details | ||
| Corporacion de Beneficencia Osorno | Osorno | Los Lagos | 5311092 | Chile | Details | |
| Clinical Research Chile SpA | Valdivia | Los Rios | 5090000 | Chile | Details | |
| Oncovida | Santiago | 7500000 | Chile | Details | ||
| Clinica Santa Maria | Santiago | 7520349 | Chile | Details | ||
| Fundación Arturo López Pérez (FALP) - PPDS | Santiago | 7850000 | Chile | Details | ||
| Centro Investigacion Clinica Del Sur | Temuco | 4810371 | Chile | Details | ||
| Oncocentro APYS | Viña Del Mar | 2520612 | Chile | Details | ||
| Centro de Investigaciones Clínicas Vina del Mar | Viña Del Mar | 2540364 | Chile | Details | ||
| Health Pharma Professional Research S.A de C.V. | Ciudad de Mexico | Distrito Federal | 03810 | Mexico | Details | |
| Centro de Investigacion Clinica Chapultepec S.A. de C.V. | Morelia | Michoacan | 58260 | Mexico | Details | |
| Axis Heilsa S. De R.L. de C.V. | Monterrey | Nuevo León | 64060 | Mexico | Details | |
| Accelerium, S. de R.L. de C.V. | Monterrey | 64000 | Mexico | Details | ||
| Unidad Médica Onco-Hematológica | Puebla | CP 72530 | Mexico | Details | ||
| Auckland City Hospital | Auckland | 1023 | New Zealand | Details | ||
| Clinica Peruana Americana | Trujillo | La Lobertad | 13000 | Peru | Details | |
| Clinica Internacional S.A. - Sede San Borja | Lima | 15036 | Peru | Details | ||
| ONCOCARE S.A.C. (Clinica Aliada) | Lima | 15036 | Peru | Details | ||
| Hospital Nacional Cayetano Heredia | Lima | 15102 | Peru | Details | ||
| Altay Regional Oncology Center | Barnaul | 656049 | Russian Federation | Details | ||
| Chelyabinsk Regional Clinical Oncology Dispensary | Chelyabinsk | 454087 | Russian Federation | Details | ||
| LLC Evimed | Chelyabinsk | 454087 | Russian Federation | Details | ||
| Kursk Regional Oncology Centre | Kursk | 305035 | Russian Federation | Details | ||
| Central Clinical Hospital With Polyclinic of President Administration of RF | Moscow | 121359 | Russian Federation | Details | ||
| Federal State Institution Medical Radiology Research Center | Obninsk | 249036 | Russian Federation | Details | ||
| Clinical Oncology Dispensary | Omsk | 644013 | Russian Federation | Details | ||
| PMI Euromedservice | Pushkin | 196603 | Russian Federation | Details | ||
| Hospital Orkli LLC | Saint Petersburg | 194044 | Russian Federation | Details | ||
| Railway Clinical Hospital JSC RZhD | Saint Petersburg | 195271 | Russian Federation | Details | ||
| Hospital Orkli LLC | Saint Petersburg | 197136 | Russian Federation | Details | ||
| State Institution of Healthcare "Volgograd Regional Urology and Nephrology Centre" | Volzhskiy | 404120 | Russian Federation | Details | ||
| Regional Clinical Oncology Hospital | Yaroslavl | 150040 | Russian Federation | Details | ||
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| Oncocare Cancer Centre | Singapore | 258500 | Singapore | Details |