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| NCT ID | NCT03745222 |
| Title | A Study of Tislelizumab (BGB-A317) Plus Chemoradiotherapy Followed by Tislelizumab Monotherapy in Newly Diagnosed, Stage III Subjects With Locally Advanced, Unresectable Non-small Cell Lung Cancer (RATIONALE001) |
| Acronym | RATIONALE001 |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Celgene |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ROU | POL | NZL | NLD | ITA | IRL | HUN | GRC | GBR | FRA | FIN | ESP | DEU | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| Cancer Specialists of North Florida - Jacksonville | Jacksonville | Florida | 32258-5472 | United States | Details | |
| Bond Clinic, P.A. | Winter Haven | Florida | 33881 | United States | Details | |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46845 | United States | Details | |
| Appalachian Regional Healthcare, Inc. | Hazard | Kentucky | 41701 | United States | Details | |
| Norton Healthcare - Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| Center For Cancer and Blood Disorders | Bethesda | Maryland | 20817 | United States | Details | |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States | Details | |
| Dayton Physicians, LLC | Kettering | Ohio | 45409 | United States | Details | |
| Mercy Health Youngstown Hospital, LLC | Youngstown | Ohio | 44504 | United States | Details | |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
| Millennium Oncology | Houston | Texas | 77090 | United States | Details | |
| Medical Oncology Associates, P.S. | Spokane | Washington | 99208 | United States | Details | |
| Universitair Ziekenhuis Brussel | Brussels | 1090 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium | Details | ||
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Cancer Hospital Chinese Academy of Medical Sciences | Beijing | 100021 | China | Details | ||
| Chinese PLA General Hospital / 307 Hospital | Beijing | 100071 | China | Details | ||
| Beijing Cancer Hospital - Beijing Institute for Cancer Research | Beijing | 100142 | China | Details | ||
| Bengbu Medical College - First Affiliated Hospital | Bengbu Shi | 233004 | China | Details | ||
| Jilin Province Cancer Hospital | Changchun Shi | 130012 | China | Details | ||
| First Hospital of Jilin University | Changchun | 130021 | China | Details | ||
| Central South University - Xiangya School of Medicine - Hunan Cancer Hospital | Changsha-shi | 410013 | China | Details | ||
| Central South University - Xiangya School of Medicine - Hunan Cancer Hospital | Changsha | 410013 | China | Details | ||
| Sichuan Cancer Hospital & Institute | Chengdu | 610041 | China | Details | ||
| Sichuan University - West China Hospital | Chengdu | 610041 | China | Details | ||
| Foshan First People's Hospital | Foshan | 528000 | China | Details | ||
| Fujian Medical University - Fujian Provincial Cancer Hospital | Fuzhou Shi | 350014 | China | Details | ||
| Cancer Center of Guangzhou Medical University | Guangzhou | 510095 | China | Details | ||
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou | 510120 | China | Details | ||
| Zhejiang University School of Medicine - The Second Affiliated Hospital | Hangzhou | 310016 | China | Details | ||
| Zhejiang Medical University - Zhejiang Cancer Hospital | Hangzhou | 310022 | China | Details | ||
| The First Affiliated Hospital of Harbin Medical University | Harbin | 150081 | China | Details | ||
| Yunnan Cancer Hospital | Kunming Shi | 650118 | China | Details | ||
| Guangxi Tumour Institute and Hospital | Nanning | 530021 | China | Details | ||
| Nantong Tumor Hospital | Nantong | 226361 | China | Details | ||
| Shanghai Chest Hospital | Shanghai Shi | 200030 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
| Chongqing Cancer Hospital | Shapingbaqu | 400030 | China | Details | ||
| Liaoning Cancer Hospital & Institute | Shenyang Shi | 110042 | China | Details | ||
| The First Hospital of Xinjiang Medical University | Urumqi | 830054 | China | Details | ||
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Wuhan | 430022 | China | Details | ||
| Zhongnan Hospital of Wuhan University | Wuhan | 430023 | China | Details | ||
| Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology | Wuhan | 430030 | China | Details | ||
| The First Affiliated Hospital of Xi'an Jiaotong University | Xi'an City | 710061 | China | Details | ||
| First Hospital of Xiamen | Xiamen | 361003 | China | Details | ||
| The Affiliated Hospital of Xuzhou Medical University | Xuzhou | 221002 | China | Details | ||
| Zhengzhou University (ZZU) - Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| The First Affiliated Hospital of Zhengzhou University | Zhengzhou | 450052 | China | Details | ||
| Tampereen yliopistollinen sairaala | Tampere | 33521 | Finland | Details | ||
| Turku University Hospital | Turku | 20521 | Finland | Details | ||
| Centre Francois Baclesse | Caen Cedex 5 | 14076 | France | Details | ||
| Clinique Victor Hugo | Le Mans | 72015 | France | Details | ||
| Institut de Cancerologie de l'Ouest (ICO) - Saint-Herblain | Saint Herblain | 44805 | France | Details | ||
| Medical Study Company NORD-WEST GmbH Oncology Aurich | Aurich | 26603 | Germany | Details | ||
| Helios Klinikum Emil Von Behring | Berlin | 14165 | Germany | Details | ||
| Florence Nightingale KH der Kaiserwerther Diakonie | Dusseldorf | 40489 | Germany | Details | ||
| Klinikum Esslingen GmbH | Esslingen Am Neckar | 73730 | Germany | Details | ||
| Asklepios Fachkliniken Muenchen Gauting | Gauting | 82131 | Germany | Details | ||
| Oncological practice Goslar | Goslar | 38642 | Germany | Details | ||
| Evangelisches Krankenhaus Hamm | Hamm | 59063 | Germany | Details | ||
| Health Nordhessen Holding AG - Klinikum Kassel - Medical Clinic IV | Kassel | 34125 | Germany | Details | ||
| Kliniken der Stadt Koln gGmbH - Krankenhaus Merheim | Koln | 51109 | Germany | Details | ||
| Klinik Loewenstein gGmbH | Loewenstein | 74245 | Germany | Details | ||
| LMU Klinikum der Universität | München | 81377 | Germany | Details | ||
| St. Antonius-Hospital | Schweiler | 52249 | Germany | Details | ||
| Medizinische Studiengesellschaft Nord-West | Westerstede | 26655 | Germany | Details | ||
| Sotiria Chest Hospital of Athens | Athens | 11527 | Greece | Details | ||
| IASO General | Athens | 15562 | Greece | Details | ||
| University General Hospital of Heraklion | Heraklion | 71110 | Greece | Details | ||
| Agioi Anargyroi Cancer Hospital | Kifissia | 14564 | Greece | Details | ||
| Metaxa Cancer Hospital of Piraeus | Piraeus | 18537 | Greece | Details | ||
| Interbalkan Medical Center of Thessaloniki | Pylaia | 570 01 | Greece | Details | ||
| University General Hospital of Patras | Rio Patras | 26500 | Greece | Details | ||
| Bioclinic Thessaloniki Galinos clinic | Thessaloniki | 54622 | Greece | Details | ||
| EUROMEDICA General Clinic of Thessaloniki | Thessaloniki | 54645 | Greece | Details | ||
| Papageorgiou General Hospital of Thessaloniki | Thessaloniki | 56429 | Greece | Details | ||
| Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz | Szekesfehervar | 8000 | Hungary | Details | ||
| Pulmonary Institute Torokbalint | Torokbalint | 2045 | Hungary | Details | ||
| Beacon Hospital | Dublin | D18 AK68 | Ireland | Details | ||
| St James Hospital | Dublin | Dublin 8 | Ireland | Details | ||
| MidWestern Regional Hospital | Limerick | Ireland | Details | |||
| Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele - Ospedale Gaspare Rodolico | Catania | 95123 | Italy | Details | ||
| IRCCS AziendaOspedaliera Universitaria San Martino | Genova | 16132 | Italy | Details | ||
| Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori (I.R.S.T.) | Meldola | 47014 | Italy | Details | ||
| Universita Campus Bio-Medico di Roma | Roma | 00128 | Italy | Details | ||
| Istituto Nazionale Tumori Regina Elena di Roma | Roma | 00144 | Italy | Details | ||
| Osaka Prefectural Medical Center for Respiratory and Allergic Diseases | Habikino-shi | 583-8588 | Japan | Details | ||
| Kansai Medical University Hospital | Hirakata-shi | 573-1191 | Japan | Details | ||
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa-shi | Japan | Details | |||
| Matsusaka Municipal Hospital | Matsusaka-shi | 515-8544 | Japan | Details | ||
| Toranomon Hospital | Minato-ku | 105-8470 | Japan | Details | ||
| Iwate Medical University Hospital | Morioka | 020-8505 | Japan | Details | ||
| National Hospital Organization - Nagoya Medical Center | Nagoya-shi | 460-0001 | Japan | Details | ||
| Nagoya University Hospital | Nagoya-shi | 466-8560 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata-shi | 951-8566 | Japan | Details | ||
| Osaka City University Hospital | Osaka | 545-8586 | Japan | Details | ||
| Gunma Prefectural Cancer Center | Ota-ku | 373-8550 | Japan | Details | ||
| Kitasato University Hospital | Sagamihara | 252-0375 | Japan | Details | ||
| Sendai Kousei Hospital | Sendai-shi | 980-0873 | Japan | Details | ||
| Kanagawa Cardiovascular and Respiratory Center | Yokohama-shi | 236-0051 | Japan | Details | ||
| Yokohama Municipal Citizen's Hospital | Yokohama-shi | 240-8555 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju | 138-736 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 5505 | Korea, Republic of | Details | ||
| Ajou University Hospital | Suwon si | 16499 | Korea, Republic of | Details | ||
| Vrije Universiteit Medisch Centrum (VUMC) | Amsterdam | 1081 HV | Netherlands | Details | ||
| Gelre Hospitals | Zutphen | 7207 AE | Netherlands | Details | ||
| Waikato Hospital | Hamilton | 3204 | New Zealand | Details | ||
| Tauranga Hospital | Tauranga | 3112 | New Zealand | Details | ||
| Centrum Onkologii im. prof. Franciszka Lukaszczyka w Bydgoszczy | Bydgoszcz | 85796 | Poland | Details | ||
| Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie | Gliwice | 44-101 | Poland | Details | ||
| Med Polonia Sp. z o.o. NSZOZ | Poznan | 60-693 | Poland | Details | ||
| Centrum Onkologii-Instytut im.Marii Sklodowskiej-Curie | Warszawa | 02-781 | Poland | Details | ||
| Hospital Prof. Doutor Fernando Fonseca | Amadora | 2720-276 | Portugal | Details | ||
| Centro Hospitalar E Universitario de Coimbra EPE | Coimbra | 3000-075 | Portugal | Details | ||
| Centro Hospitalar do Alto Ave, Hospital da Senhora da Oliveira Guimaraes | Guimaraes | 4835-044 | Portugal | Details | ||
| CUF Descobertas Hospital | Lisboa | 1998-018 | Portugal | Details | ||
| Centro Hospitalar do Porto - Hospital de Santo António | Porto | 4099-001 | Portugal | Details | ||
| CUF Porto Hospital | Porto | 4100-180 | Portugal | Details | ||
| Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe | Porto | 4200-072 | Portugal | Details | ||
| Oncology Institute Professor Doctor Alexandru Trestioreanu | Bucharest | 022328 | Romania | Details | ||
| Prof. Dr. I. Chiricuta Institute of Oncology | Cluj-Napoca | 400015 | Romania | Details | ||
| Medisprof SRL | Cluj-Napoca | 400058 | Romania | Details | ||
| Sf. Apostol Andrei Constanta Emergency Clinical County Hospital | Constanta | 900591 | Romania | Details | ||
| Oncology Center Sfantul Nectarie | Craiova | Romania | Details | |||
| Life Search SRL | Timisoara | 300167 | Romania | Details | ||
| Oncocenter Clinical Oncology | Timisoara | 300210 | Romania | Details | ||
| Principal Military Clinical Hospital n.a. N.N. Burdenko | Moscow | 105229 | Russian Federation | Details | ||
| Omsk Regional Oncology Center | Omsk | 610013 | Russian Federation | Details | ||
| Ryazan State Medical University n.a. I.P. Pavlov | Ryazan | 390026 | Russian Federation | Details | ||
| Mordovia State University | Saransk | 43002 | Russian Federation | Details | ||
| Clinical Hospital of the Russian Academy of Sciences | St. Petersburg | 194017 | Russian Federation | Details | ||
| GBUZ Saint Petersburg Clinical Research Center of Specialized Types of Care (Oncology) | St. Petersburg | 197758 | Russian Federation | Details | ||
| Research Oncology Institute of Rosmed Technologies n.a. prof. N.N. Petrov | St. Petersburg | 197758 | Russian Federation | Details | ||
| National University Hospital | Singapore | 119074 | Singapore | Details | ||
| Raffles Hospital | Singapore | 188770 | Singapore | Details | ||
| Hospital Universitario a Coruna | A Coruna | 15006 | Spain | Details | ||
| Hospital General Universitario de Alicante | Alicante | 03010 | Spain | Details | ||
| Hospital Universitario Germans Trias i Pujol | Barcelona | 08916 | Spain | Details | ||
| Insular-Maternal and Child University Hospital Complex | Las Palmas de Gran Canaria | 35016 | Spain | Details | ||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario Puerta de Hierro-Majadahonda | Majadahonda, Madrid | 28222 | Spain | Details | ||
| Hospital General Carlos Haya | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario Central de Asturias | Oviedo | 33011 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | 46026 | Spain | Details | ||
| Buddhist Dalin Tzu Chi General Hospital | Dalin | 62247 | Taiwan | Details | ||
| Kaohsiung Medical University Hospital | Kaohsiung, San Ming Dist. | 807 | Taiwan | Details | ||
| E-DA Hospital | Kaohsiung | 82445 | Taiwan | Details | ||
| Chang Gung Medical Foundation, Kaohsiung Memorial Hospital | Niao-Sung Hsiang Kaohsiung County | 83301 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei, Zhongzheng Dist. | 100 | Taiwan | Details | ||
| University Hospitals Birmingham NHS Foundation Trust - Queen Elizabeth Hospital | Birmingham | B15 2TH | United Kingdom | Details | ||
| East Suffolk and North Essex NHS Foundation Trust - Colchester Hospital | Colchester | CO4 5JL | United Kingdom | Details | ||
| University College London Hospitals NHS Foundation Trust - University College Hospital | London | NW1 2BU | United Kingdom | Details | ||
| Guys Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Royal Marsden Hospital | London | SW3 6JJ | United Kingdom | Details | ||
| Maidstone and Tunbridge Wells NHS Trust - Maidstone Hospital | Maidstone | ME16 9QQ | United Kingdom | Details | ||
| Manchester University NHS Foundation Trust - Wythenshawe Hospital - North West Lung Centre | Manchester | M23 9LT | United Kingdom | Details | ||
| The Hillingdon Hospitals NHS Foundation Trust - Mount Vernon Hospital | Northwood | HA6 2RN | United Kingdom | Details | ||
| Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital | Sheffield South Yorkshire | S10 2SS | United Kingdom | Details | ||
| Royal Cornwall Hospitals Trust | Truro | TR1 3LJ | United Kingdom | Details |