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| NCT ID | NCT03833167 |
| Title | Pembrolizumab Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ROU | POL | NZL | NOR | ITA | ISR | IRL | HUN | GRC | GBR | FRA | ESP | DEU | CAN | BRA | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of South Alabama, Mitchell Cancer Institute ( Site 1562) | Mobile | Alabama | 36604 | United States | Details | |
| City of Hope Medical Center ( Site 1505) | Duarte | California | 91010 | United States | Details | |
| UCSD Moores Cancer Center ( Site 1561) | La Jolla | California | 92093-0698 | United States | Details | |
| UCLA Hematology/Oncology - Westwood (Building 100) ( Site 1568) | Los Angeles | California | 90095 | United States | Details | |
| University of California Davis Comprehensive Cancer Center ( Site 1560) | Sacramento | California | 95817 | United States | Details | |
| Stanford University Medical Center ( Site 1503) | Stanford | California | 94305 | United States | Details | |
| University of Colorado Cancer Center ( Site 1506) | Aurora | Colorado | 80045 | United States | Details | |
| Smilow Cancer Center at Yale-New Haven ( Site 1507) | New Haven | Connecticut | 06510 | United States | Details | |
| Boca Raton Regional Hospital ( Site 1551) | Boca Raton | Florida | 33486 | United States | Details | |
| UF Health ( Site 1511) | Gainesville | Florida | 32608 | United States | Details | |
| University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 1544) | Miami | Florida | 33136 | United States | Details | |
| Winship Cancer Institute of Emory University ( Site 1512) | Atlanta | Georgia | 30322-1013 | United States | Details | |
| Indiana University Melvin and Bren Simon Cancer Center ( Site 1515) | Indianapolis | Indiana | 46202 | United States | Details | |
| University of Iowa Hospital and Clinics ( Site 1514) | Iowa City | Iowa | 52242 | United States | Details | |
| University of Kentucky School of Medicine & Hospitals ( Site 1542) | Lexington | Kentucky | 40536 | United States | Details | |
| Massachusetts General Hospital ( Site 1518) | Boston | Massachusetts | 02114 | United States | Details | |
| Dana Farber Cancer Center ( Site 1519) | Boston | Massachusetts | 02215 | United States | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center ( Site 1526) | Hackensack | New Jersey | 07601 | United States | Details | |
| Northwell Health/ RJ Zuckerberg Cancer Center-Medical Oncology ( Site 1565) | Lake Success | New York | 11042 | United States | Details | |
| Icahn School of Medicine at Mount Sinai ( Site 1575) | New York | New York | 10029 | United States | Details | |
| Cleveland Clinic ( Site 1541) | Cleveland | Ohio | 44195 | United States | Details | |
| Providence Portland Medical Center ( Site 1530) | Portland | Oregon | 97213 | United States | Details | |
| UPMC Hillman Cancer Center ( Site 1570) | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| MUSC Hollings Cancer Center ( Site 1533) | Charleston | South Carolina | 29425 | United States | Details | |
| West Cancer Center - East Campus ( Site 1535) | Germantown | Tennessee | 38138 | United States | Details | |
| Vanderbilt Ingram Cancer Center ( Site 1543) | Nashville | Tennessee | 37232 | United States | Details | |
| The University of Texas-MD Anderson Cancer Center ( Site 1536) | Houston | Texas | 77030 | United States | Details | |
| Huntsman Cancer Institute ( Site 1537) | Salt Lake City | Utah | 84112 | United States | Details | |
| Inova Schar Cancer Institute ( Site 1538) | Fairfax | Virginia | 22031 | United States | Details | |
| West Virginia University ( Site 1569) | Morgantown | West Virginia | 26506 | United States | Details | |
| Centro de Investigaciones Metabólicas (CINME)-Oncology ( Site 0028) | Ciudad Autónoma de Buenos Aires | Buenos Aires | C1027AAP | Argentina | Details | |
| Centro Medico Privado CEMAIC ( Site 0024) | Capital | Cordoba | X5008HHW | Argentina | Details | |
| Fundacion Estudios Clinicos-Oncology ( Site 0026) | Rosario | Santa Fe | S2000DEJ | Argentina | Details | |
| Centro Oncológico de Rosario ( Site 0003) | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Hospital Italiano- Sociedad Italiana de Beneficencia en Buenos Aires ( Site 0009) | Buenos Aires | C1181ACH | Argentina | Details | ||
| CEMIC ( Site 0012) | Buenos Aires | C1431FWO | Argentina | Details | ||
| Fundacion CIDEA ( Site 0001) | Caba | C1121ABE | Argentina | Details | ||
| Centro Oncologico Riojano Integral ( Site 0002) | La Rioja | F5300COE | Argentina | Details | ||
| Centro Oncologico Norte ( Site 0023) | Santiago del Estero | G4200AWD | Argentina | Details | ||
| Chris OBrien Lifehouse ( Site 0051) | Camperdown | New South Wales | 2050 | Australia | Details | |
| Lismore Base Hospital ( Site 0050) | Lismore | New South Wales | 2480 | Australia | Details | |
| Orange Health Services ( Site 0053) | Orange | New South Wales | 2800 | Australia | Details | |
| Royal North Shore Hospital ( Site 0052) | St Leonards | New South Wales | 2065 | Australia | Details | |
| Gold Coast University Hospital ( Site 0054) | Southport | Queensland | 4215 | Australia | Details | |
| Sunshine Coast University Private Hospital-Coastal Cancer Care ( Site 0056) | Sunshine Coast | Queensland | 4575 | Australia | Details | |
| Alfred Health ( Site 0055) | Melbourne | Victoria | 3004 | Australia | Details | |
| Oncocentro Ceara ( Site 0108) | Fortaleza | Ceara | 60135-237 | Brazil | Details | |
| Hospital Erasto Gaertner ( Site 0101) | Curitiba | Parana | 81520-060 | Brazil | Details | |
| Hospital Tacchini ( Site 0111) | Bento Goncalves | Rio Grande Do Sul | 95700-084 | Brazil | Details | |
| ONCOSITE - Centro de Pesquisa Clinica em Oncologia ( Site 0100) | Ijui | Rio Grande Do Sul | 98700000 | Brazil | Details | |
| Hospital Bruno Born ( Site 0107) | Lajeado | Rio Grande Do Sul | 95900-000 | Brazil | Details | |
| Hospital Sao Vicente de Paulo ( Site 0105) | Passo Fundo | Rio Grande Do Sul | 99010-080 | Brazil | Details | |
| Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA-Pesquisa Clinica HC II ( Site 0103) | Rio de Janeiro | 20220-410 | Brazil | Details | ||
| A. C. Camargo Cancer Center ( Site 0116) | Sao Paulo | 01509-010 | Brazil | Details | ||
| Tom Baker Cancer Center ( Site 0161) | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Cross Cancer Institute ( Site 0159) | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Juravinski Cancer Center ( Site 0151) | Hamilton | Ontario | L8V 1C3 | Canada | Details | |
| The Ottawa Hospital Cancer Centre ( Site 0154) | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0163) | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| McGill University Health Centre ( Site 0162) | Montréal | Quebec | H4A 3J1 | Canada | Details | |
| James Lind Centro de Investigación del Cáncer ( Site 1653) | Temuco | Araucania | 4800827 | Chile | Details | |
| Enroll SpA ( Site 1654) | Santiago | Region M. De Santiago | 7500587 | Chile | Details | |
| Bradfordhill ( Site 1651) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| Bradford Hill Norte ( Site 1652) | Antofagasta | 1240000 | Chile | Details | ||
| Oncomedica S.A. ( Site 0205) | Monteria | Cordoba | 230002 | Colombia | Details | |
| Sociedad de Cirugía de Bogotá - Hospital de San Jose ( Site 0201) | Bogota | Distrito Capital De Bogota | 111411 | Colombia | Details | |
| Instituto Nacional de Cancerologia E.S.E ( Site 0204) | Bogota | Distrito Capital De Bogota | 111511 | Colombia | Details | |
| Oncologos del Occidente S.A. ( Site 0206) | Pereira | Risaralda | 660001 | Colombia | Details | |
| Fundación Cardiovascular de Colombia ( Site 0207) | Piedecuesta | Santander | 68017 | Colombia | Details | |
| Fundación Valle del Lili ( Site 0202) | Cali | Valle Del Cauca | 760032 | Colombia | Details | |
| Hopital ARCHET 2 ( Site 0356) | Nice | Alpes-Maritimes | 06200 | France | Details | |
| Hopital Saint Joseph ( Site 0376) | Marseille | Bouches-du-Rhone | 13285 | France | Details | |
| Hopital La Timone ( Site 0353) | Marseille | Bouches-du-Rhone | 13385 | France | Details | |
| Centre Hospitalier Universitaire de Caen Normandie-DERMATOLOGY ( Site 0365) | Caen | Calvados | 14000 | France | Details | |
| CHU Besancon - Hopital Jean Minjoz ( Site 0359) | Besancon | Doubs | 25030 | France | Details | |
| Centre Hospitalier de Valence ( Site 0377) | Valence | Drome | 26953 | France | Details | |
| C.H.U. de Nimes. Hopital Caremeau ( Site 0368) | Nimes | Gard | 30029 | France | Details | |
| CHU de Bordeaux- Hopital Saint Andre ( Site 0370) | Bordeaux | Gironde | 33075 | France | Details | |
| Institut Claudius Regaud IUCT Oncopole ( Site 0354) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Centre Hospitalier Annecy Genevois ( Site 0361) | Pringy | Haute-Savoie | 74374 | France | Details | |
| CHU Montpellier. ( Site 0367) | Montpellier | Herault | 34295 | France | Details | |
| CHRU de Lille - Hopital Claude Huriez ( Site 0355) | Lille | Nord | 59037 | France | Details | |
| CHU Estaing ( Site 0360) | Clermont-Ferrand | Puy-de-Dome | 63003 | France | Details | |
| CH Lyon Sud Hospices Civils de Lyon ( Site 0350) | Pierre Benite | Rhone | 69495 | France | Details | |
| Hopital Avicenne ( Site 0358) | Bobigny | Seine-Saint-Denis | 93009 | France | Details | |
| Institut Gustave Roussy ( Site 0352) | Villejuif | Val-de-Marne | 94800 | France | Details | |
| CHU Poitiers ( Site 0375) | Poitiers | Vienne | 86021 | France | Details | |
| Universitaetsklinikum Tuebingen ( Site 0409) | Tuebingen | Baden-Wurttemberg | 72076 | Germany | Details | |
| Klinikum Nürnberg Nord ( Site 0415) | Nürnberg | Bayern | 90419 | Germany | Details | |
| Universitatsklinikum Giessen und Marburg GmbH ( Site 0413) | Marburg | Hessen | 35043 | Germany | Details | |
| Elbe Kliniken Stade-Buxtehude, Klinikum Buxtehude-Dermatologisches Zentrum ( Site 0411) | Buxtehude | Niedersachsen | 21614 | Germany | Details | |
| Medizinische Hochschule Hannover ( Site 0405) | Hannover | Niedersachsen | 30625 | Germany | Details | |
| Universitaetsklinikum Essen ( Site 0403) | Essen | Nordrhein-Westfalen | 45147 | Germany | Details | |
| Universitaetsklinikum Berlin - Charite - Campus Mitte ( Site 0400) | Berlin | 10117 | Germany | Details | ||
| Universitaetsklinikum Hamburg-Eppendorf ( Site 0414) | Hamburg | 20246 | Germany | Details | ||
| Andreas Syggros Hospital ( Site 0450) | Athens | Achaia | 161 21 | Greece | Details | |
| Attikon University General Hospital of Athens ( Site 0454) | Chaidari | Attiki | 124 62 | Greece | Details | |
| Metropolitan Hospital ( Site 0453) | Neo Faliro | Attiki | 185 47 | Greece | Details | |
| Papageorgiou General Hospital ( Site 0451) | Thessaloniki | 564 03 | Greece | Details | ||
| European Interbalkan Medical Center ( Site 0455) | Thessaloniki | 570 01 | Greece | Details | ||
| Pecsi Tudomanyegyetem AOK ( Site 0501) | Pecs | Baranya | 7632 | Hungary | Details | |
| Szegedi Tudomanyegyetem ( Site 0504) | Szeged | Csongrad | 6720 | Hungary | Details | |
| Szabolcs Szatmar Bereg Megyei Korhazak es Egyetemi Oktatokorhaz ( Site 0500) | Nyiregyhaza | Szabolcs-Szatmar-Bereg | 4400 | Hungary | Details | |
| Debreceni Egyetem. ( Site 0506) | Debrecen | Vas | 4032 | Hungary | Details | |
| Semmelweis Egyetem ( Site 0507) | Budapest | 1083 | Hungary | Details | ||
| Szent Imre Egyetemi Oktatokorhaz ( Site 0502) | Budapest | 1115 | Hungary | Details | ||
| St. James s Hospital ( Site 1601) | Dublin 8 | Dublin | D08 K0Y5 | Ireland | Details | |
| Soroka University Medical Center ( Site 0555) | Beer Sheva | 8410101 | Israel | Details | ||
| Rambam Health Care Campus-Oncology Division ( Site 0552) | Haifa | 3109601 | Israel | Details | ||
| Haddassah Medical Organization - Ein Kerem ( Site 0553) | Jerusalem | 9112001 | Israel | Details | ||
| Meir Medical Center ( Site 0556) | Kfar-Saba | 4428132 | Israel | Details | ||
| Rabin Medical Center ( Site 0550) | Petah Tiqwa | 4941492 | Israel | Details | ||
| Chaim Sheba Medical Center ( Site 0551) | Ramat Gan | 5265601 | Israel | Details | ||
| Sourasky Medical Center ( Site 0554) | Tel-Aviv | 6423906 | Israel | Details | ||
| Instituto Tumori Giovanni Paolo II ( Site 0604) | Bari | Puglia | 70124 | Italy | Details | |
| Azienda Ospedaliero Universitaria Pisana ( Site 0603) | Pisa | Toscana | 56126 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0600) | Milano | 20133 | Italy | Details | ||
| Istituto Europeo di Oncologia ( Site 0602) | Milano | 20141 | Italy | Details | ||
| Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 0601) | Napoli | 80131 | Italy | Details | ||
| San Lucas Cardiologica del Sureste S.A de C.V. ( Site 0722) | Tuxtla Gutierrez | Chiapas | 29090 | Mexico | Details | |
| Cimab SA de CV ( Site 0708) | Torreon | Coahuila | 27000 | Mexico | Details | |
| Centro de Investigación Clínica de Alta Especialidad ( Site 0715) | Torreón | Coahuila | 27010 | Mexico | Details | |
| Onco-Hematologia de Occidente ( Site 0716) | Guadalajara | Jalisco | 44260 | Mexico | Details | |
| Hospital de Especialidades Centro Medico de Occidente ( Site 0704) | Guadalajara | Jalisco | 44349 | Mexico | Details | |
| Consultorios de Medicina Especializada del Sector Privado ( Site 0701) | Guadalajara | Jalisco | 44680 | Mexico | Details | |
| Centro de atencion e investigacion clinica en oncologia ( Site 0706) | Merida | Yucatan | 97134 | Mexico | Details | |
| Centro Estatal de Cancerologia de Chihuahua ( Site 0703) | Chihuahua | 31000 | Mexico | Details | ||
| FAICIC Clinical Research ( Site 0700) | Veracruz | 91900 | Mexico | Details | ||
| New Zealand Clinical Research (Auckland) ( Site 0800) | Auckland | 0624 | New Zealand | Details | ||
| Haukeland sykehus ( Site 0851) | Bergen | Hordaland | 5021 | Norway | Details | |
| St. Olavs Hospital HF ( Site 0852) | Trondheim | Sor-Trondelag | 7030 | Norway | Details | |
| Oslo Universitetssykehus Radiumhospitalet ( Site 0850) | Oslo | 0379 | Norway | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Oddzial w Krakowie ( Site 0959) | Krakow | Malopolskie | 31-115 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0951) | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Uniwersyteckie Centrum Kliniczne-Klinika Chirurgii Onkologicznej, Transplantacyjnej i Ogólnej ( Site | Gdańsk | Pomorskie | 80-214 | Poland | Details | |
| Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 0958) | Gliwice | Slaskie | 44-101 | Poland | Details | |
| Hospital Particular do Algarve ( Site 1005) | Faro | 8005-226 | Portugal | Details | ||
| Instituto Portugues de Oncologia de Lisboa ( Site 1003) | Lisboa | 1099-023 | Portugal | Details | ||
| Hospital CUF - Tejo ( Site 1004) | Lisboa | 1350-352 | Portugal | Details | ||
| CHLN Hospital Santa Maria ( Site 1001) | Lisboa | 1649-035 | Portugal | Details | ||
| Inst. Portugues de Oncologia de Porto Francisco Gentil EPE ( Site 1000) | Porto | 4200-072 | Portugal | Details | ||
| S C Pelican Impex SRL ( Site 1108) | Oradea | Bihor | 410469 | Romania | Details | |
| Hifu Terramed Conformal SRL ( Site 1111) | Bucharest | Bucuresti | 031864 | Romania | Details | |
| Cardiomed SRL Cluj-Napoca ( Site 1104) | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1113) | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| Spitalul Universitar CF Cluj-Napoca ( Site 1103) | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1101) | Craiova | Dolj | 200347 | Romania | Details | |
| S C Oncocenter Oncologie Medicala S R L ( Site 1106) | Timisoara | Timis | 300166 | Romania | Details | |
| Policlinica Oncomed SRL ( Site 1105) | Timisoara | Timis | 300239 | Romania | Details | |
| S.C.Focus Lab Plus S.R.L ( Site 1107) | Bucuresti | 022548 | Romania | Details | ||
| Spitalul de Psihiatrie Titan Dr. Constantin Gorgos ( Site 1112) | Bucuresti | 030447 | Romania | Details | ||
| Altay Regional Oncology Dispensary ( Site 1168) | WBarnaularsaw | Altayskiy Kray | 656045 | Russian Federation | Details | |
| GBUZ Republican Clinical Oncological Dispensary-Antitumor drug therapy department ( Site 1171) | Ufa | Baskortostan, Respublika | 450054 | Russian Federation | Details | |
| A. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological | Obninsk | Kaluzskaja Oblast | 249036 | Russian Federation | Details | |
| Oncological Dispensary #2 of Ministry of Health of Krasnodar region ( Site 1159) | Sochi | Krasnodarskiy Kray | 354057 | Russian Federation | Details | |
| Hadassah Medical-Oncology department ( Site 1173) | Moscow | Moskovskaya Oblast | 121205 | Russian Federation | Details | |
| N.N. Blokhin NMRCO ( Site 1153) | Moscow | Moskva | 115478 | Russian Federation | Details | |
| FSCC FMBA of Russia ( Site 1163) | Moscow | Moskva | 115682 | Russian Federation | Details | |
| First Moscow State Medical University n.a. I.M.Sechenov ( Site 1164) | Moscow | Moskva | 119991 | Russian Federation | Details | |
| Nizhniy Novgorod regional clinical oncological dispensary ( Site 1169) | Nizhny Novgorod | Nizhegorodskaya Oblast | 603126 | Russian Federation | Details | |
| Railway Hospital of OJSC ( Site 1161) | Saint Petersburg | Sankt-Peterburg | 195271 | Russian Federation | Details | |
| Udmurtia Republic Regional Clinical Oncology Dispensary ( Site 1158) | Izhevsk | Udmurtskaya Respublika | 426009 | Russian Federation | Details | |
| Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 1152) | Yaroslavl | Yaroslavskaya Oblast | 150054 | Russian Federation | Details | |
| Hospital Duran i Reynals ( Site 1254) | Hospitalet del Llobregat | Barcelona | 08908 | Spain | Details | |
| Hospital Universitario Marques de Valdecilla ( Site 1256) | Santander | Cantabria | 39008 | Spain | Details | |
| Hospital Clinic i Provincial Barcelona ( Site 1253) | Barcelona | Cataluna | 08036 | Spain | Details | |
| Onkologikoa - Instituto Oncologico de San Sebastian ( Site 1258) | Doniostia - San Sebastian | Gipuzkoa | 20014 | Spain | Details | |
| Hospital General Universitari Vall d Hebron ( Site 1252) | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal ( Site 1251) | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Carlos Haya ( Site 1255) | Malaga | 29010 | Spain | Details | ||
| Communal Non-Commercial Enterprise "Prykarpatski Clinical On-Department for daily treated patient ( | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
| Institute of General and Emergency Surgery named after V.T. Zaitsev NAMS of Ukraine ( Site 1450) | Kharkiv | Kharkivska Oblast | 61103 | Ukraine | Details | |
| Limited Liability Company Ukrainian Center of Tomotherapy-Department of Chemotherapy ( Site 1451) | Kropyvnytskyi | Kirovohradska Oblast | 25011 | Ukraine | Details | |
| Sumy regional clinical oncological dispensary-Oncothoracic department ( Site 1452) | Sumy | Sumska Oblast | 40022 | Ukraine | Details | |
| Universal Clinic Oberig-Oncology Center ( Site 1461) | Kyiv | 03057 | Ukraine | Details | ||
| Royal Cornwall Hospitals NHS Trust ( Site 1402) | Truro | Cornwall | TR1 3LQ | United Kingdom | Details | |
| University College Hospital London ( Site 1400) | London | London, City Of | NW1 2PG | United Kingdom | Details | |
| Guy s & St Thomas NHS Foundation Trust ( Site 1407) | London | London, City Of | SE1 9RT | United Kingdom | Details | |
| The Royal Marsden Hospital-Institute of Cancer Research ( Site 1406) | London | London, City Of | SW3 6JJ | United Kingdom | Details | |
| Royal Marsden NHS Foundation Trust ( Site 1408) | Sutton | London, City Of | SM2 5PT | United Kingdom | Details | |
| Churchill Hospital ( Site 1404) | Oxford | Oxfordshire | OX3 7LE | United Kingdom | Details |