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NCT ID NCT03834506
Title Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)
Recruitment Completed
Gender male
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | NLD | ITA | ISR | IRL | GBR | FRA | ESP | DEU | CAN | BRA | AUT | AUS | ARG

Facility Status City State Zip Country Details
University of South Alabama, Mitchell Cancer Institute ( Site 0065) Mobile Alabama 36604 United States Details
St. Joseph Heritage Healthcare ( Site 0069) Fullerton California 92835 United States Details
University of Southern California Norris Comprehensive Cancer Center ( Site 0061) Los Angeles California 90033 United States Details
USC Norris Oncology Hematology Newport Beach ( Site 0093) Newport Beach California 92663 United States Details
University of California San Francisco ( Site 0023) San Francisco California 94158 United States Details
University of Colorado Cancer Center ( Site 0022) Aurora Colorado 80045 United States Details
Yale Cancer Center ( Site 0038) New Haven Connecticut 06510 United States Details
Moffitt Cancer Center ( Site 0080) Tampa Florida 33612 United States Details
Georgia Cancer Center at Augusta University ( Site 0026) Augusta Georgia 30912 United States Details
Mount Sinai Hospital Medical Center ( Site 0042) Chicago Illinois 60608 United States Details
Methodist Hospital- Merriillville ( Site 0008) Merrillville Indiana 46410 United States Details
Karmanos Cancer Institute ( Site 0077) Detroit Michigan 48201 United States Details
Henry Ford Health System ( Site 0039) Detroit Michigan 48202-2608 United States Details
Cancer & Hematology Centers of Western Michigan ( Site 0013) Grand Rapids Michigan 49503 United States Details
Washington University School of Medicine ( Site 0057) Saint Louis Missouri 63110 United States Details
St. Vincent Frontier Cancer Center ( Site 0016) Billings Montana 59102 United States Details
Nebraska Cancer Specialists ( Site 0034) Omaha Nebraska 68130 United States Details
Comprehensive Cancer Centers of Nevada ( Site 0092) Las Vegas Nevada 89169 United States Details
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0004) Hackensack New Jersey 07601 United States Details
Associated Medical Professionals of NY ( Site 0060) Syracuse New York 13210 United States Details
Duke Cancer Center ( Site 0010) Durham North Carolina 27710 United States Details
W. G. Bill Hefner VA Medical Center ( Site 0029) Salisbury North Carolina 28144 United States Details
University Hospitals Cleveland Medical Center ( Site 0036) Cleveland Ohio 44106 United States Details
Oregon Health Sciences University ( Site 0031) Portland Oregon 97239 United States Details
Carolina Urologic Research Center ( Site 0070) Myrtle Beach South Carolina 29572 United States Details
Inova Schar Cancer Institute ( Site 0006) Fairfax Virginia 22031-4867 United States Details
Virginia Cancer Institute ( Site 0052) Richmond Virginia 23230 United States Details
Blue Ridge Cancer Care ( Site 0086) Roanoke Virginia 24014 United States Details
Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 1013) Berazategui Buenos Aires B1884BBF Argentina Details
Instituto de Investigaciones Clinicas ( Site 1000) Mar del Plata Buenos Aires B7600FZN Argentina Details
Centro de Diagnostico Urologico ( Site 1008) Buenos Aires Caba C1120AAT Argentina Details
Hospital Britanico de Buenos Aires ( Site 1006) Buenos Aires Caba C1280AEB Argentina Details
Sanatorio Parque ( Site 1002) Rosario Santa Fe S2000DSV Argentina Details
Instituto de Investigaciones Metabolicas [Buenos Aires, Argentina] ( Site 1011) Buenos Aires C1012AAR Argentina Details
Hospital Aleman ( Site 1004) Buenos Aires C1118AAT Argentina Details
Instituto Medico Alexander Fleming ( Site 1010) Buenos Aires C1426ANZ Argentina Details
CEMAIC ( Site 1014) Cordoba X5008HHW Argentina Details
St George Hospital ( Site 0157) Kogarah New South Wales 2217 Australia Details
Macquarie University ( Site 0151) Macquarie University New South Wales 2109 Australia Details
Port Macquarie Base Hospital ( Site 0153) Port Macquarie New South Wales 2444 Australia Details
Calvary Mater Newcastle ( Site 0148) Waratah New South Wales 2298 Australia Details
Redcliffe Hospital ( Site 0161) Redcliffe Queensland 4020 Australia Details
John Flynn Hospital & Medical Centre ( Site 0164) Tugun Queensland 4224 Australia Details
Hollywood Private Hospital ( Site 0163) Nedlands Western Australia 6009 Australia Details
Ordensklinikum Linz GmbH Elisabethinen ( Site 0373) Linz Oberosterreich 4020 Austria Details
Medizinische Universitat Graz ( Site 0374) Graz Steiermark 8036 Austria Details
SCRI-CCCIT GesmbH ( Site 0371) Salzburg 5020 Austria Details
Medizinische Universitaet Wien ( Site 0375) Wien 1090 Austria Details
Hospital de Caridade de Ijui ( Site 1038) Ijui Rio Grande Do Sul 98700-000 Brazil Details
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 1021) Porto Alegre Rio Grande Do Sul 90610-000 Brazil Details
Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 1035) Itajai Santa Catarina 88301-215 Brazil Details
Hospital de Base de Sao Jose de Rio Preto ( Site 1022) Sao Jose do Rio Preto Sao Paulo 15090-000 Brazil Details
A.C. Camargo Cancer Center ( Site 1026) Sao Paulo 01509-900 Brazil Details
Nova Scotia Health Authority QEII-HSC ( Site 0114) Halifax Nova Scotia B3H 2Y9 Canada Details
Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0116) Hamilton Ontario L8V5C2 Canada Details
Grand River Hospital ( Site 0120) Kitchener Ontario N2G 1G3 Canada Details
Lakeridge Health ( Site 0117) Oshawa Ontario L1G 2B9 Canada Details
Sunnybrook Research Institute ( Site 0108) Toronto Ontario M4N 3M5 Canada Details
Princess Margaret Cancer Centre ( Site 0107) Toronto Ontario M5G 2M9 Canada Details
CIUSSS du Bas Saint Laurent - Hopital Regional de Rimouski ( Site 0102) Rimouski Quebec G5L 5T1 Canada Details
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0105) Sherbrooke Quebec J1H 5N4 Canada Details
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec ( Site 0103) Quebec G1R 2J6 Canada Details
Centro Investigación del Cáncer James Lind ( Site 1041) Temuco Araucania 4780000 Chile Details
Rey y Oreilly Limitada ( Site 1048) Temuco Araucania 4810148 Chile Details
Fundacion Arturo Lopez Perez ( Site 1049) Santiago Region M. De Santiago 7500921 Chile Details
Pontificia Universidad Catolica de Chile ( Site 1047) Santiago Region M. De Santiago 8330032 Chile Details
Bradford Hill Centro de Investigaciones Clinicas ( Site 1044) Santiago Region M. De Santiago 8420383 Chile Details
Centro de Investigaciones Clinicas Vina del Mar ( Site 1042) Vina del Mar Valparaiso 2540488 Chile Details
Peking University First Hospital ( Site 1303) Beijing Beijing 100034 China Details
The Fifth Medical Center of PLA General Hospital ( Site 1307) Beijing Beijing 100071 China Details
Beijing Cancer Hospital ( Site 1305) Beijing Beijing 100142 China Details
The First Affiliated Hospital of Xiamen University ( Site 1319) Xiamen Fujian 361003 China Details
Sun Yat Sen Memorial Hospital ( Site 1323) Guangzhou Guangdong 510220 China Details
The First Affiliated Hospital of Guangzhou Medical University ( Site 1330) Guangzhou Guangdong 510230 China Details
Harbin Medical University Cancer Hospital ( Site 1326) Harbin Heilongjiang 150081 China Details
Henan Cancer Hospital ( Site 1321) Zhengzhou Henan 450008 China Details
Hubei Cancer Hospital ( Site 1329) Wuhan Hubei 430079 China Details
Hunan Cancer Hospital ( Site 1320) Changsha Hunan 410013 China Details
Nanjing Drum Tower Hospital ( Site 1312) Nanjing Jiangsu 210008 China Details
Fudan University Shanghai Cancer Center ( Site 1300) Shanghai Shanghai 200032 China Details
Zhongshan Hospital Fudan University ( Site 1301) Shanghai Shanghai 200032 China Details
The Second Affiliated Hospital of Zhejiang University School of Medicine ( Site 1309) Hangzhou Zhejiang 310009 China Details
Zhejiang Provincial People's Hospital ( Site 1310) Hangzhou Zhejiang 310014 China Details
Hospital Pablo Tobon Uribe ( Site 1066) Medellin Antioquia 050034 Colombia Details
Biomelab S A S ( Site 1067) Barranquilla Atlantico 080002 Colombia Details
Clinica de la Costa Ltda. ( Site 1073) Barranquilla Atlantico 080020 Colombia Details
Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 1068) Valledupar Cesar 200001 Colombia Details
Oncomedica S.A. ( Site 1057) Monteria Cordoba 230002 Colombia Details
Instituto Nacional de Cancerologia E.S.E ( Site 1061) Bogota Distrito Capital De Bogota 110321 Colombia Details
Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 1062) Bogota Distrito Capital De Bogota 111321 Colombia Details
Oncologos del Occidente S.A. ( Site 1072) Pereira Risaralda 660001 Colombia Details
Centro Medico Imbanaco de Cali S.A ( Site 1064) Cali Valle Del Cauca 760042 Colombia Details
Hemato Oncologos S.A. ( Site 1065) Cali Valle Del Cauca 760042 Colombia Details
C.H. de Saint Quentin ( Site 0481) Saint Quentin Aisne 02321 France Details
Clinique Sainte Anne ( Site 0431) Strasbourg Alsace 67000 France Details
Centre Jean Perrin ( Site 0434) Clermont-Ferrand Auvergne 63011 France Details
Centre Leon Berard ( Site 0422) Lyon Auvergne 69373 France Details
Institut Paoli Calmettes. ( Site 0419) Marseille Bouches-du-Rhone 13009 France Details
CHU Jean Minjoz ( Site 0423) Besancon Doubs 25000 France Details
CHU de Brest -Site Hopital Morvan ( Site 0441) Brest Finistere 29200 France Details
Institut Bergonie ( Site 0421) Bordeaux Gironde 33076 France Details
Institut Claudius Regaud IUCT Oncopole ( Site 0418) Toulouse Haute-Garonne 31059 France Details
Hopital Foch ( Site 0428) Suresnes Hauts-de-Seine 92151 France Details
Institut De Cancerologie De L Ouest ( Site 0448) Saint Herblain Loire-Atlantique 44805 France Details
Centre Hospitalier Regional du Orleans ( Site 0430) Orleans Loiret 45100 France Details
Centre D Oncologie de Gentilly ( Site 0432) Nancy Meurthe-et-Moselle 54100 France Details
C.H.U. Lyon Sud ( Site 0436) Pierre Benite Rhone 69310 France Details
CHU Amiens Picardie Site Sud Amiens ( Site 0438) Amiens Somme 80000 France Details
Institut Gustave Roussy ( Site 0416) Villejuif Val-de-Marne 94800 France Details
Institut Sainte Catherine ( Site 0447) Avignon Vaucluse 84000 France Details
Institut Mutualiste Montsouris ( Site 0446) Paris 75014 France Details
Universitaetsklinikum Freiburg - Medizinische Klinik ( Site 0304) Freiburg Baden-Wurttemberg 79106 Germany Details
Universitaetsklinikum in Mannheim ( Site 0314) Mannheim Baden-Wurttemberg 68167 Germany Details
Studienpraxis Urologie ( Site 0309) Nuertingen Baden-Wurttemberg 72622 Germany Details
Universitaetsklinik fuer Urologie ( Site 0307) Tuebingen Baden-Wurttemberg 72076 Germany Details
Klinikum Rechts der Isar ( Site 0300) Muenchen Bayern 81675 Germany Details
Universitaetsklinik der Paracelsus Medizinischen Privatuniversitaet ( Site 0318) Nuernberg Bayern 90419 Germany Details
Universitaetsklinikum Wuerzburg ( Site 0302) Wuerzburg Bayern 97080 Germany Details
Universitaetsklinikum Goettingen ( Site 0345) Goettingen Niedersachsen 37075 Germany Details
Uniklinik RWTH Aachen ( Site 0308) Aachen Nordrhein-Westfalen 52074 Germany Details
Universitaetsklinikum des Saarlandes ( Site 0348) Homburg Saarland 66421 Germany Details
Universitaetsklinikum Jena ( Site 0305) Jena Thuringen 07747 Germany Details
Charite Universitaetsmedizin Berlin ( Site 0301) Berlin 10117 Germany Details
Cork University Hospital ( Site 0727) Cork T12 YE02 Ireland Details
Tallaght University Hospital ( Site 0730) Dublin D24 NROA Ireland Details
Mid Western Cancer Centre ( Site 0728) Limerick Ireland Details
Soroka Medical Center ( Site 0548) Beer Sheva 8410101 Israel Details
Assaf Harofeh MC ( Site 0547) Beer Yaakov-Zerifin 7030001 Israel Details
Rambam Medical Center ( Site 0543) Haifa 3109601 Israel Details
Hadassah Ein Kerem Medical Center ( Site 0546) Jerusalem 9112001 Israel Details
Meir Medical Center ( Site 0544) Kfar Saba 4428164 Israel Details
Rabin Medical Center ( Site 0545) Petach-Tikwa 4941492 Israel Details
Chaim Sheba Medical Center ( Site 0541) Ramat Gan 5262000 Israel Details
Sourasky Medical Center ( Site 0542) Tel Aviv 6423906 Israel Details
Istituto Clinico Humanitas Research Hospital ( Site 0452) Rozzano Milano 20089 Italy Details
Azienda Ospedaliera Cannizzaro ( Site 0458) Catania 95126 Italy Details
A.O. Universitaria di Modena ( Site 0454) Modena 41100 Italy Details
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 0457) Napoli 80131 Italy Details
Azienda Ospedaliera San Camillo Forlanini ( Site 0455) Roma 00152 Italy Details
Azienda Ospedaliera Santa Maria Terni ( Site 0456) Terni 05100 Italy Details
Presidio Ospedaliero Santa Chiara ( Site 0451) Trento 38122 Italy Details
National Cancer Center Hospital East ( Site 0702) Kashiwa Chiba 277-8577 Japan Details
Toho University Sakura Medical Center ( Site 0703) Sakura Chiba 285-8741 Japan Details
National Hospital Organization Shikoku Cancer Center ( Site 0716) Matsuyama Ehime 791-0280 Japan Details
Kanazawa University Hospital ( Site 0701) Kanazawa Ishikawa 920-8641 Japan Details
Kitasato University Hospital ( Site 0705) Sagamihara Kanagawa 252-0375 Japan Details
Yokohama City University Medical Center ( Site 0706) Yokohama Kanagawa 232-0024 Japan Details
Nara Medical University Hospital ( Site 0715) Kashihara Nara 634-8522 Japan Details
Kindai University Hospital ( Site 0714) Osakasayama Osaka 589-8511 Japan Details
Osaka University Hospital ( Site 0713) Suita Osaka 565-0871 Japan Details
Saitama Medical University International Medical Center ( Site 0708) Hidaka Saitama 1932 Japan Details
Dokkyo Medical University Saitama Medical Center ( Site 0707) Koshigaya Saitama 343-8555 Japan Details
Hamamatsu University Hospital ( Site 0720) Hamamatsu Shizuoka 431-3192 Japan Details
Yamaguchi University Hospital ( Site 0717) Ube Yamaguchi 755-8505 Japan Details
Chiba Cancer Center ( Site 0704) Chiba 260-8717 Japan Details
Kyushu University Hospital ( Site 0718) Fukuoka 812-8582 Japan Details
University of Miyazaki Hospital ( Site 0721) Miyazaki 889-1692 Japan Details
Nagasaki University Hospital ( Site 0719) Nagasaki 852-8501 Japan Details
Toranomon Hospital ( Site 0711) Tokyo 105-8470 Japan Details
Nippon Medical School Hospital ( Site 0709) Tokyo 113-8603 Japan Details
Keio University Hospital ( Site 0710) Tokyo 160-8582 Japan Details
National Cancer Center ( Site 0174) Goyang-si Kyonggi-do 10408 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 0175) Seongnam-si Kyonggi-do 13620 Korea, Republic of Details
Seoul National University Hospital ( Site 0171) Seoul 03080 Korea, Republic of Details
Asan Medical Center ( Site 0176) Seoul 05505 Korea, Republic of Details
Samsung Medical Center ( Site 0172) Seoul 06351 Korea, Republic of Details
Medisch Centrum Leeuwarden ( Site 0477) Leeuwarden Fryslan 8934 AD Netherlands Details
Ziekenhuis Gelderse Vallei ( Site 0485) Ede Gelderland 6746 RP Netherlands Details
Radboud University Medical Center ( Site 0470) Nijmegen Gelderland 6525 GA Netherlands Details
VieCuri Medisch Centrum ( Site 0487) Venlo Limburg 5912 BL Netherlands Details
Jeroen Bosch Ziekenhuis ( Site 1200) Den Bosch Noord-Brabant 5223 GZ Netherlands Details
Catharina Ziekenhuis ( Site 0472) Eindhoven Noord-Brabant 5623 EJ Netherlands Details
Antoni van Leeuwenhoek Ziekenhuis ( Site 0480) Amsterdam Noord-Holland 1066 CX Netherlands Details
Ziekenhuis Hilversum ( Site 0466) Hilversum Noord-Holland 1213 XZ Netherlands Details
Ziekenhuisgroep Twente ( Site 0469) Hengelo Overijssel 7555 DL Netherlands Details
Reinier de Graaf Groep ( Site 0484) Delft Zuid-Holland 2625 AD Netherlands Details
Hagaziekenhuis ( Site 1201) Den Haag Zuid-Holland 2545 AA Netherlands Details
Chelyabinsk Regional Clinical Oncological Dispensary ( Site 0565) Chelyabinsk Chelyabinskaya Oblast 454087 Russian Federation Details
Krasnoyarsk Regional Clinical Oncological Dispensary ( Site 0585) Krasnoyarsk Krasnoyarskiy Kray 660133 Russian Federation Details
SBIH City clinical hospital named after D.D. Pletniov ( Site 0575) Moscow Moskva 105077 Russian Federation Details
Russian Scientific Center of Radiology ( Site 0559) Moscow Moskva 117485 Russian Federation Details
Central Clinical Hospital with Polyclinic ( Site 0562) Moscow Moskva 121359 Russian Federation Details
National Medical Research Radiological Center ( Site 0556) Moscow Moskva 125284 Russian Federation Details
Volga District Medical Center Federal Medical and Biological Agency ( Site 0572) Nizhny Novgorod Nizhegorodskaya Oblast 603074 Russian Federation Details
Omsk Clinical Oncology Dispensary ( Site 0568) Omsk Omskaya Oblast 644013 Russian Federation Details
SBHI Samara Regional Clinical Oncology Dispensary ( Site 0576) Samara Samarskaya Oblast 443031 Russian Federation Details
Clinical Research Center of specialized types medical care-Oncology ( Site 0570) Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
Russian Scientific Center of Radiology and Surgical Technologies ( Site 0567) Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
SPb SBHI City Clinical Oncological Dispensary ( Site 0571) Saint Petersburg Sankt-Peterburg 198255 Russian Federation Details
Leningrad Regional Oncology Center ( Site 0588) Saint-Petersburg Sankt-Peterburg 188663 Russian Federation Details
Tomsk National Research Medical Center of Russian Academy of Sciences ( Site 0579) Tomsk Tomskaya Oblast 634050 Russian Federation Details
Instituto Catalan de Oncologia - ICO ( Site 0330) L Hospitalet De Llobregat Barcelona 08908 Spain Details
Hospital Consorci Sanitari Parc Tauli ( Site 0335) Sabadell Barcelona 08208 Spain Details
Hospital Universitario Marques de Valdecilla ( Site 0336) Santander Cantabria 39008 Spain Details
Hospital Josep Trueta ( Site 0321) Girona Gerona 17007 Spain Details
Hospital del Mar ( Site 0333) Barcelona 08003 Spain Details
Hospital Clinic ( Site 0323) Barcelona 08036 Spain Details
Hospital Universitario Ramon y Cajal ( Site 0328) Madrid 28034 Spain Details
Hospital Clinico San Carlos ( Site 0324) Madrid 28040 Spain Details
Hospital Universitario HM Sanchinarro ( Site 0322) Madrid 28050 Spain Details
Hospital Universitario Virgen de la Victoria ( Site 0337) Malaga 29016 Spain Details
Hospital Virgen del Rocio ( Site 0329) Sevilla 41013 Spain Details
National Cheng Kung University Hospital ( Site 0134) Tainen Tainan 704 Taiwan Details
China Medical University Hospital ( Site 0132) Taichung 40447 Taiwan Details
Taichung Veterans General Hospital ( Site 0133) Taichung 40705 Taiwan Details
National Taiwan University Hospital ( Site 0131) Taipei 10048 Taiwan Details
Taipei Veterans General Hospital ( Site 0135) Taipei 11217 Taiwan Details
University Hospitals Bristol NHS Foundation Trust ( Site 0530) Bristol Bristol, City Of BS2 8ED United Kingdom Details
Cambridge University Hospitals NHS Trust ( Site 0540) Cambridge Cambridgeshire CB2 0QQ United Kingdom Details
Torbay Hospital ( Site 0532) Torquay Devon TQ2 7AA United Kingdom Details
Weston Park Hospital ( Site 0539) Sheffield England S10 2SJ United Kingdom Details
Royal Marsden Hospital ( Site 0526) Sutton England SM2 5PT United Kingdom Details
Mount Vernon Cancer Centre ( Site 0536) Northwood Hertfordshire HA6 2RN United Kingdom Details
Barts Cancer Institute ( Site 0483) London London, City Of EC1A 7BE United Kingdom Details
University of North Midlands NHS Foundation Trust ( Site 0527) Stoke-on-Trent Staffordshire ST4 6QG United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field