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| NCT ID | NCT03834961 |
| Title | Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Children's Oncology Group |
| Indications | |
| Therapies | |
| Age Groups: | child | adult |
| Covered Countries | USA | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Children's Hospital of Alabama | Birmingham | Alabama | 35233 | United States | Details | |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202-3591 | United States | Details | |
| Kaiser Permanente Downey Medical Center | Downey | California | 90242 | United States | Details | |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | United States | Details | |
| Children's Hospital of Orange County | Orange | California | 92868 | United States | Details | |
| UCSF Medical Center-Mission Bay | San Francisco | California | 94158 | United States | Details | |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | United States | Details | |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Denver | Colorado | 80218 | United States | Details | |
| Yale University | New Haven | Connecticut | 06520 | United States | Details | |
| Alfred I duPont Hospital for Children | Wilmington | Delaware | 19803 | United States | Details | |
| MedStar Georgetown University Hospital | Washington | District of Columbia | 20007 | United States | Details | |
| Children's National Medical Center | Washington | District of Columbia | 20010 | United States | Details | |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | United States | Details | |
| Golisano Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | United States | Details | |
| University of Florida Health Science Center - Gainesville | Gainesville | Florida | 32610 | United States | Details | |
| Nemours Children's Clinic-Jacksonville | Jacksonville | Florida | 32207 | United States | Details | |
| Jackson Memorial Hospital-Holtz Children's Hospital | Miami | Florida | 33136 | United States | Details | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | United States | Details | |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | United States | Details | |
| Nemours Children's Hospital | Orlando | Florida | 32827 | United States | Details | |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Tampa | Florida | 33607 | United States | Details | |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital | Atlanta | Georgia | 30329 | United States | Details | |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | United States | Details | |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | United States | Details | |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | United States | Details | |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | United States | Details | |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | United States | Details | |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | United States | Details | |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | United States | Details | |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| C S Mott Children's Hospital | Ann Arbor | Michigan | 48109 | United States | Details | |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | United States | Details | |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | United States | Details | |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | United States | Details | |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States | Details | |
| Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | United States | Details | |
| Cardinal Glennon Children's Medical Center | Saint Louis | Missouri | 63104 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Mercy Hospital Saint Louis | Saint Louis | Missouri | 63141 | United States | Details | |
| Children's Hospital and Medical Center of Omaha | Omaha | Nebraska | 68114 | United States | Details | |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | United States | Details | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Morristown Medical Center | Morristown | New Jersey | 07960 | United States | Details | |
| Montefiore Medical Center - Moses Campus | Bronx | New York | 10467 | United States | Details | |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | United States | Details | |
| Mission Hospital | Asheville | North Carolina | 28801 | United States | Details | |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | United States | Details | |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | United States | Details | |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | United States | Details | |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States | Details | |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | United States | Details | |
| Dayton Children's Hospital | Dayton | Ohio | 45404 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Oregon Health and Science University | Portland | Oregon | 97239 | United States | Details | |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | United States | Details | |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Saint Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | United States | Details | |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | United States | Details | |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | United States | Details | |
| BI-LO Charities Children's Cancer Center | Greenville | South Carolina | 29605 | United States | Details | |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105 | United States | Details | |
| Dell Children's Medical Center of Central Texas | Austin | Texas | 78723 | United States | Details | |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | United States | Details | |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | United States | Details | |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | United States | Details | |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | United States | Details | |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23507 | United States | Details | |
| Seattle Children's Hospital | Seattle | Washington | 98105 | United States | Details | |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99204 | United States | Details | |
| Mary Bridge Children's Hospital and Health Center | Tacoma | Washington | 98405 | United States | Details | |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | United States | Details | |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | United States | Details | |
| Children's Hospital of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| IWK Health Centre | Halifax | Nova Scotia | B3K 6R8 | Canada | Details | |
| Centre Hospitalier Universitaire Sainte-Justine | Montreal | Quebec | H3T 1C5 | Canada | Details |