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| NCT ID | NCT03839771 |
| Title | A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy (HOVON150AML) |
| Acronym | HOVON150AML |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Stichting Hemato-Oncologie voor Volwassenen Nederland |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | SWE | NOR | NLD | LUX | LTU | IRL | FRA | FIN | EST | ESP | DEU | CHE | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| AU-Adelaide-FLINDERS | Adelaide | Australia | Details | |||
| AU-Adelaide-RAH | Adelaide | Australia | Details | |||
| AU-Brisbane-PAH | Brisbane | Australia | Details | |||
| AU-Camperdown-RPA | Camperdown | Australia | Details | |||
| AU-Canberra-CANBERRAHOSPITAL | Canberra | Australia | Details | |||
| AU-Douglas-TOWNSVILLE | Douglas | Australia | Details | |||
| AU-Hobart TAS-RHOBART | Hobart | Australia | Details | |||
| AU-Launceston TAS-LAUNCESTON | Launceston | Australia | Details | |||
| AU-Melbourne-ALFRED | Melbourne | Australia | Details | |||
| AU-Melbourne-AUSTIN | Melbourne | Australia | Details | |||
| AU-Melbourne-MONASH | Melbourne | Australia | Details | |||
| AU-Melbourne-RMELBOURNE | Melbourne | Australia | Details | |||
| AU-Melbourne-SVHM | Melbourne | Australia | Details | |||
| AU-Perth-FSH | Perth | Australia | Details | |||
| AU-Perth-RPH | Perth | Australia | Details | |||
| AU-Perth-SCGH | Perth | Australia | Details | |||
| AU-Sydney-CONCORD | Sydney | Australia | Details | |||
| AU-Sydney-RNSH | Sydney | Australia | Details | |||
| AU-Sydney-SVHS | Sydney | Australia | Details | |||
| AU-Sydney-WSAH | Sydney | Australia | Details | |||
| AU-Waratah-CALVARYMATER | Waratah | Australia | Details | |||
| AT-Graz-MEDUNIGRAZ | Graz | Austria | Details | |||
| AT-Innsbruck-IMED | Innsbruck | Austria | Details | |||
| AT-Linz-ORDENSKLINIKUM | Linz | Austria | Details | |||
| AT-Vienna-HANUSCH | Vienna | Austria | Details | |||
| BE-Antwerpen-ZNASTUIVENBERG | Antwerpen | Belgium | Details | |||
| BE-Brugge-AZBRUGGE | Brugge | Belgium | Details | |||
| BE-Brussel-BORDET | Brussels | Belgium | Details | |||
| BE-Brussel-UZBRUSSEL | Brussels | Belgium | Details | |||
| BE-Bruxelles-STLUC | Brussels | Belgium | Details | |||
| BE-Gent-UZGENT | Gent | Belgium | Details | |||
| BE-Haine-Saint-Paul-JOLIMONT | Haine-Saint-Paul | Belgium | Details | |||
| BE-Hasselt-VIRGAJESSE | Hasselt | Belgium | Details | |||
| BE-Leuven-UZLEUVEN | Leuven | Belgium | Details | |||
| BE-Liege-CHRCITADELLE | Liège | Belgium | Details | |||
| BE-Liege-CHULIEGE | Liège | Belgium | Details | |||
| BE-Roeselare-AZDELTA | Roeselare | Belgium | Details | |||
| BE-Yvoir-MONTGODINNE | Yvoir | Belgium | Details | |||
| EE-Tartu-TARTU | Tartu | Estonia | Details | |||
| FI-Helsinki-HUS | Helsinki | Finland | Details | |||
| FI-Tampere-TAYS | Tampere | Finland | Details | |||
| FR-Amiens-CHUAMIENS | Amiens | France | Details | |||
| FR-Angers-CHUANGERS | Angers | France | Details | |||
| FR-Argenteuil-CHARGENTEUIL | Argenteuil | France | Details | |||
| FR-Bayonne-CHCOTEBASQUE | Bayonne | France | Details | |||
| FR-Besançon Cedex-JEANMINJOZ | Besançon | France | Details | |||
| FR-Bobigny-AVICENNE | Bobigny | France | Details | |||
| FR-Chambery-CHMETROPOLESAVOIE | Chambéry | France | Details | |||
| FR-Le Chesnay cedex-CHVERSAILLES | Chesnay | France | Details | |||
| FR-Clamart-HIAPERCY | Clamart | France | Details | |||
| FR-Clermont-Ferrand-ESTAING | Clermont-Ferrand | France | Details | |||
| FR-Créteil cedex-CHUMONDOR | Créteil | France | Details | |||
| FR-Grenoble cedex 9-CHUGRENOBLE | Grenoble cedex 9 | France | Details | |||
| FR-Lens-CHLENS | Lens | France | Details | |||
| FR-Lille-CHULILLE | Lille | France | Details | |||
| FR-Limoges-CHULIMOGES | Limoges | France | Details | |||
| FR-Lyon Pierre Benite cedex-LYONSUD | Lyon | France | Details | |||
| FR-Lyon-LEONBERARD | Lyon | France | Details | |||
| FR-Marseille-IPC | Marseille | France | Details | |||
| FR-Montpellier-STELOI | Montpellier | France | Details | |||
| FR-Mulhouse-GHRMSA | Mulhouse | France | Details | |||
| FR-Nantes-CHUNANTES | Nantes | France | Details | |||
| FR-Nice-CAL | Nice | France | Details | |||
| FR-Nice-LARCHET | Nice | France | Details | |||
| FR-Orléans-CHORLEANS | Orléans | France | Details | |||
| FR-Paris cedex 10-SAINTLOUIS | Paris | France | Details | |||
| FR-Paris cedex 12-SAINTANTOINE | Paris | France | Details | |||
| FR-Paris cedex 15-NECKER | Paris | France | Details | |||
| FR-Pessac Cedex-CHUBORDEAUX | Pessac | France | Details | |||
| FR-Poitiers-CHUPOITERS | Poitiers | France | Details | |||
| FR-Reims-CHREIMS | Reims | France | Details | |||
| FR-Rennes cedex 9-CHURENNES | Rennes | France | Details | |||
| FR-Rouen cedex-BECQUEREL | Rouen | France | Details | |||
| FR-Strasbourg cedex-HAUTEPIERRE | Strasbourg | France | Details | |||
| FR-Toulouse-CHUTOULOUSE | Toulouse | France | Details | |||
| FR-Tours cedex-BRETONNEAU | Tours | France | Details | |||
| FR-Vandoeuvre Les Nancy-CHRUNANCY | Vandœuvre-lès-Nancy | France | Details | |||
| FR-Villejuif-GUSTAVEROUSSY | Villejuif | France | Details | |||
| DE-Bad Saarow-HELIOSBADSAAROW | Bad Saarow | Germany | Details | |||
| DE-Berlin-CAMPUSBENFRANKLIN | Berlin | Germany | Details | |||
| DE-Berlin-CAMPUSVIRCHOW | Berlin | Germany | Details | |||
| DE-Berlin-VIVANTESNEUKOLLN | Berlin | Germany | Details | |||
| DE-Berlin-VIVANTESURBAN | Berlin | Germany | Details | |||
| DE-Bochum-RUB | Bochum | Germany | Details | |||
| DE-Bonn-UNIBONN | Bonn | Germany | Details | |||
| DE-Braunschweig-KLINIKUMBRAUNSCHWEIG | Braunschweig | Germany | Details | |||
| DE-Bremen-KBM | Bremen | Germany | Details | |||
| DE-Dortmund-JOHODORTMUND | Dortmund | Germany | Details | |||
| DE-Düsseldorf-MEDUNIDUESSELDORF | Düsseldorf | Germany | Details | |||
| DE-Essen-KEM | Essen | Germany | Details | |||
| DE-Esslingen-KLINIKUMESSLINGEN | Esslingen | Germany | Details | |||
| DE-Flensburg-MALTESER | Flensburg | Germany | Details | |||
| DE-Giessen-UKGM | Gießen | Germany | Details | |||
| DE-Goch-KKLE | Goch | Germany | Details | |||
| DE-Hamburg-ASKLEPIOSSTGEORG | Hamburg | Germany | Details | |||
| DE-Hamburg-ASKLEPIOS | Hamburg | Germany | Details | |||
| DE-Hamburg-UKE | Hamburg | Germany | Details | |||
| DE-Hamm-EVKHAMM | Hamm | Germany | Details | |||
| DE-Hanau-KLINIKUMHANAU | Hanau | Germany | Details | |||
| DE-Hannover-MHHANNOVER | Hannover | Germany | Details | |||
| DE-Hannover-SILOAHKRH | Hannover | Germany | Details | |||
| DE-Herne-MARIENHOSPITALHERNE | Herne | Germany | Details | |||
| DE-Homburg-UNIKLINIKSAARLAND | Homburg | Germany | Details | |||
| DE-Karlsruhe-KLINIKUMKARLSRUHE | Karlsruhe | Germany | Details | |||
| DE-Lebach-CARITASKHLEBACH | Lebach | Germany | Details | |||
| DE-Lemgo-KLINIKUMLIPPE | Lemgo | Germany | Details | |||
| DE-Ludwigshafen-KLILU | Ludwigshafen | Germany | Details | |||
| DE-Luedenscheid-KLINIKUMLUEDENSCHEID | Lüdenscheid | Germany | Details | |||
| DE-Magdeburg-OVGU | Magdeburg | Germany | Details | |||
| DE-Mainz-KLINKUNIMAINZ | Mainz | Germany | Details | |||
| DE-Mainz-UNIMEDIZINMAINZ | Mainz | Germany | Details | |||
| DE-Meschede-HOCHSAUERLAND | Meschede | Germany | Details | |||
| DE-Minden-MUEHLENKREISKLINKEN | Minden | Germany | Details | |||
| DE-München-IRZTUM | München | Germany | Details | |||
| DE-München-MEDUNIMUNCHIN | München | Germany | Details | |||
| DE-Offenburg-ORTENAUKLINIKUM | Offenburg | Germany | Details | |||
| DE-Oldenburg-KLINIKUMOLDENBURG | Oldenburg | Germany | Details | |||
| DE-Passau-KLINIKUMPASSAU | Passau | Germany | Details | |||
| DE-Stuttgart-DIAKSTUTTGART | Stuttgart | Germany | Details | |||
| DE-Stuttgart-KLINIKUMSTUTTGART | Stuttgart | Germany | Details | |||
| DE-Traunstein-TSSOB | Traunstein | Germany | Details | |||
| DE-Trier-MUTTERHAUS | Trier | Germany | Details | |||
| DE-Tübingen-MEDUNITUEBINGEN | Tübingen | Germany | Details | |||
| DE-Ulm-UNIKLINKULM | Ulm | Germany | Details | |||
| DE-Villingen-Schwenningen-SBKVS | Villingen-Schwenningen | Germany | Details | |||
| DE-Wuppertal-HELIOSGESUNDHEIT | Wuppertal | Germany | Details | |||
| IE-Cork-CUH | Cork | Ireland | Details | |||
| IE-Dublin 8-STJAMES | Dublin | Ireland | Details | |||
| IE-Dublin 9-BEAUMONT | Dublin | Ireland | Details | |||
| IE-Galway-UHGALWAY | Galway | Ireland | Details | |||
| LT-Vilnius-SANTA | Vilnius | Lithuania | Details | |||
| LU-Luxembourg-CHL | Luxembourg | Luxembourg | Details | |||
| NL-Amersfoort-MEANDERMC | Amersfoort | Netherlands | Details | |||
| NL-Amsterdam-AMC | Amsterdam | Netherlands | Details | |||
| NL-Amsterdam-OLVG | Amsterdam | Netherlands | Details | |||
| NL-Amsterdam-VUMC | Amsterdam | Netherlands | Details | |||
| NL-Arnhem-RIJNSTATE | Arnhem | Netherlands | Details | |||
| NL-Breda-AMPHIA | Breda | Netherlands | Details | |||
| NL-Delft-RDGG | Delft | Netherlands | Details | |||
| NL-Den Bosch-JBZ | Den Bosch | Netherlands | Details | |||
| NL-Den Haag-HAGA | Den Haag | Netherlands | Details | |||
| NL-Dordrecht-ASZ | Dordrecht | Netherlands | Details | |||
| NL-Eindhoven-MAXIMAMC | Eindhoven | Netherlands | Details | |||
| NL-Enschede-MST | Enschede | Netherlands | Details | |||
| NL-Groningen-UMCG | Groningen | Netherlands | Details | |||
| NL-Leeuwarden-MCL | Leeuwarden | Netherlands | Details | |||
| NL-Leiden-LUMC | Leiden | Netherlands | Details | |||
| NL-Maastricht-MUMC | Maastricht | Netherlands | Details | |||
| NL-Nieuwegein-ANTONIUS | Nieuwegein | Netherlands | Details | |||
| NL-Nijmegen-RADBOUDUMC | Nijmegen | Netherlands | Details | |||
| NL-Rotterdam-ErasmusMC | Rotterdam | Netherlands | Details | |||
| NL-Utrecht-UMCUTRECHT | Utrecht | Netherlands | Details | |||
| NL-Zwolle-ISALA | Zwolle | Netherlands | Details | |||
| NO-Bergen-HELSEBERGEN | Bergen | Norway | Details | |||
| NO-Oslo-OSLOUH | Oslo | Norway | Details | |||
| NO-Stavanger-HELSESTAVANGER | Stavanger | Norway | Details | |||
| NO-Tromsø-NORTHNOORWEGEN | Tromsø | Norway | Details | |||
| NO-Trondheim-STOLAV | Trondheim | Norway | Details | |||
| ES-Barcelona-CLINICUB | Barcelona | Spain | Details | |||
| ES-Barcelona-GERMANTRIALS | Barcelona | Spain | Details | |||
| ES-Barcelona-ICODURANREYNALS | Barcelona | Spain | Details | |||
| ES-Barcelona-MUTUATERRASSA | Barcelona | Spain | Details | |||
| ES-Barcelona-PARCDESALUTMAR | Barcelona | Spain | Details | |||
| ES-Barcelona-SANTPAU | Barcelona | Spain | Details | |||
| ES-Barcelona-VHEBRON | Barcelona | Spain | Details | |||
| ES-Girona-ICSTRUETA | Girona | Spain | Details | |||
| ES-Madrid-CSGREGORIOMARANON | Madrid | Spain | Details | |||
| ES-Palma-SSIB | Palma | Spain | Details | |||
| ES-Tarragona-JOAN | Tarragona | Spain | Details | |||
| ES-Valencia-MALVARROSA | Valencia | Spain | Details | |||
| SE-Lund-SUH | Lund | Sweden | Details | |||
| SE-Stockholm-KAROLINSKAHUDDINGE | Stockholm | Sweden | Details | |||
| SE-Uppsala-UPPSALAUH | Uppsala | Sweden | Details | |||
| CH-Basel-USB | Basel | Switzerland | Details | |||
| CH-Bellinzona-IOSI | Bellinzona | Switzerland | Details | |||
| CH-Bern-INSEL | Bern | Switzerland | Details | |||
| CH-Fribourg-HFR | Fribourg | Switzerland | Details | |||
| CH-Geneve (14)-HCUGE | Geneve | Switzerland | Details | |||
| CH-Luzern-LUKS | Luzern | Switzerland | Details | |||
| CH-St. Gallen-KSSG | Saint Gallen | Switzerland | Details | |||
| CH-Zürich-USZ | Zürich | Switzerland | Details |