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NCT ID | NCT03911869 |
Title | An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis (POLARIS) |
Acronym | POLARIS |
Recruitment | Terminated |
Gender | both |
Phase | Phase II |
Variant Requirements | Yes |
Sponsors | Array BioPharma |
Indications | |
Therapies | |
Age Groups: | adult | senior |
Covered Countries | USA | ITA | BEL | AUS | ARG |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
The Angeles Clinic And Research Institute, A Cedars-Sinai Affiliate | Los Angeles | California | 90025 | United States | Details | |
UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94143 | United States | Details | |
The Retina Partners | Santa Monica | California | 90404 | United States | Details | |
Rocky Mountain Lions Eye Institute (RMLEI) | Aurora | Colorado | 80045 | United States | Details | |
University of Colorado Denver CTO/CTRC - Outpatient. | Aurora | Colorado | 80045 | United States | Details | |
University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) | Aurora | Colorado | 80045 | United States | Details | |
University of Colorado Hospital - Anschutz Outpatient Pavilion | Aurora | Colorado | 80045 | United States | Details | |
University of Colorado Hospital | Aurora | Colorado | 80045 | United States | Details | |
Oregon Health & Science University Center for Health & Healing 2 | Portland | Oregon | 97239-3011 | United States | Details | |
OHSU Center for Health and Healing | Portland | Oregon | 97239 | United States | Details | |
MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
Instituto Médico Especializado Alexander Fleming | Buenos Aires | Ciudad Autónoma DE Buenosaires | CP1426ANZ | Argentina | Details | |
Instituto de Oncologia de Rosario | Rosario | Santa FE | S2000KZE | Argentina | Details | |
Fundacion CIDEA | Caba | C1121ABE | Argentina | Details | ||
Crows Nest Eye Surgery | Crows Nest | New South Wales | 2065 | Australia | Details | |
Melanoma Institute Australia | North Sydney | New South Wales | 2060 | Australia | Details | |
Royal north shore center hospital dermatology clinics | st Leonards | New South Wales | 2065 | Australia | Details | |
Mater Imaging | Wollstonecraft | New South Wales | 2065 | Australia | Details | |
UZ Antwerpen | Edegem | Antwerpen | 2650 | Belgium | Details | |
Azienda Universitaria Policlinico Federico II | Napoli | Naples | 80131 | Italy | Details | |
S.C. Cardiologia | Napoli | 80131 | Italy | Details | ||
S.C. Farmacia | Napoli | 80131 | Italy | Details | ||
S.C. Medicina Nucleare e Terapia Metabolica | Napoli | 80131 | Italy | Details | ||
SC Melanoma, Immunoterapia Oncologica e Terapie Innovative | Napoli | 80131 | Italy | Details | ||
U.O. Radiodiagnostica 1 | Napoli | 80131 | Italy | Details |